Slco1a5 (solute carrier organic anion transporter family, member 1A5) - Rat Genome Database

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Gene: Slco1a5 (solute carrier organic anion transporter family, member 1A5) Rattus norvegicus
Analyze
Symbol: Slco1a5
Name: solute carrier organic anion transporter family, member 1A5 (Ensembl:solute carrier organic anion transporter family, member 1a4)
RGD ID: 70985
Description: Enables bile acid transmembrane transporter activity and thyroid hormone transmembrane transporter activity. Involved in bile acid and bile salt transport; intestinal absorption; and liver regeneration. Located in brush border membrane. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: OATP-3; Oatp3; organic anion transporting polypeptide 3; organic anion-transporting polypeptide 3; Slc21a7; Slco1a2; sodium-independent organic anion transporter 3; solute carrier family 21 (fatty acid transporter) member 7; solute carrier family 21 (fatty acid transporter), member 7; solute carrier family 21 member 7; solute carrier organic anion transporter family member 1A5; solute carrier organic anion transporter family, member 1A2
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84176,903,387 - 176,985,589 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4176,903,330 - 176,985,563 (-)EnsemblGRCr8
mRatBN7.24175,172,390 - 175,254,598 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4174,710,004 - 175,254,573 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4181,467,207 - 181,527,647 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,251,502 - 177,311,914 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04175,872,042 - 175,932,471 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,445,856 - 176,528,117 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,445,858 - 176,528,110 (-)Ensemblrn6Rnor6.0
Rnor_5.04240,660,960 - 240,741,922 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44179,790,209 - 179,851,288 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4163,705,427 - 163,765,715 (-)NCBICelera
RGSC_v3.14180,035,332 - 180,096,412 (-)NCBI
Cytogenetic Map4q44NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
epilepsy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. Abe T, etal., J Biol Chem 1998 Aug 28;273(35):22395-401.
2. Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney. Deguchi T, etal., Kidney Int 2002 May;61(5):1760-8.
3. Oligonucleotide microarray analysis of differential transporter regulation in the regenerating rat liver. Dransfeld O, etal., Liver Int. 2005 Dec;25(6):1243-58.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Distribution of organic anion-transporting polypeptide 2 (oatp2) and oatp3 in the rat retina. Ito A, etal., Invest Ophthalmol Vis Sci 2002 Mar;43(3):858-63.
6. Transporter-mediated intestinal absorption of fexofenadine in rats. Kikuchi A, etal., Drug Metab Pharmacokinet. 2006 Aug;21(4):308-14.
7. Expression and functional involvement of organic anion transporting polypeptide subtype 3 (Slc21a7) in rat choroid plexus. Kusuhara H, etal., Pharm Res. 2003 May;20(5):720-7.
8. Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters. Leuthold S, etal., Am J Physiol Cell Physiol. 2009 Mar;296(3):C570-82. doi: 10.1152/ajpcell.00436.2008. Epub 2009 Jan 7.
9. Gene Data Set MGD Curation, June 12, 2002
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Involvement of organic anion transporting polypeptide 1a5 (Oatp1a5) in the intestinal absorption of endothelin receptor antagonist in rats. Tani T, etal., Pharm Res. 2008 May;25(5):1085-91. Epub 2007 Oct 24.
14. Expression, transport properties, and chromosomal location of organic anion transporter subtype 3. Walters HC, etal., Am J Physiol Gastrointest Liver Physiol 2000 Dec;279(6):G1188-200.
Additional References at PubMed
PMID:12606759   PMID:22899169   PMID:33132311  


Genomics

Comparative Map Data
Slco1a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84176,903,387 - 176,985,589 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4176,903,330 - 176,985,563 (-)EnsemblGRCr8
mRatBN7.24175,172,390 - 175,254,598 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4174,710,004 - 175,254,573 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4181,467,207 - 181,527,647 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,251,502 - 177,311,914 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04175,872,042 - 175,932,471 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,445,856 - 176,528,117 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,445,858 - 176,528,110 (-)Ensemblrn6Rnor6.0
Rnor_5.04240,660,960 - 240,741,922 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44179,790,209 - 179,851,288 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4163,705,427 - 163,765,715 (-)NCBICelera
RGSC_v3.14180,035,332 - 180,096,412 (-)NCBI
Cytogenetic Map4q44NCBI
Slco1a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396142,179,953 - 142,268,707 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6142,179,953 - 142,268,707 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386142,234,227 - 142,322,981 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6142,234,227 - 142,322,981 (-)Ensemblmm10GRCm38
MGSCv376142,182,750 - 142,271,470 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366142,191,452 - 142,280,172 (-)NCBIMGSCv36mm8
Celera6145,293,802 - 145,382,923 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map673.69NCBI

Variants

.
Variants in Slco1a5
473 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:306
Count of miRNA genes:198
Interacting mature miRNAs:226
Transcripts:ENSRNOT00000049569
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4176806581181925369Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
D4Rat86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24174,713,553 - 174,713,729 (+)MAPPERmRatBN7.2
Rnor_6.04175,973,096 - 175,973,271NCBIRnor6.0
Rnor_5.04240,198,494 - 240,198,669UniSTSRnor5.0
Celera4163,250,586 - 163,250,759UniSTS
RH 3.4 Map41033.9UniSTS
RH 3.4 Map41033.9RGD
RH 2.0 Map4893.2RGD
FHH x ACI Map4112.4RGD
Cytogenetic Map4q44UniSTS
D4Rat288  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24175,181,600 - 175,181,807 (+)MAPPERmRatBN7.2
Rnor_6.04176,455,129 - 176,455,335NCBIRnor6.0
Rnor_5.04240,670,233 - 240,670,439UniSTSRnor5.0
RGSC_v3.44179,799,414 - 179,799,620UniSTSRGSC3.4
Celera4163,714,632 - 163,714,838UniSTS
FHH x ACI Map4111.32UniSTS
FHH x ACI Map4111.32RGD
Cytogenetic Map4q44UniSTS
RH130074  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24174,710,134 - 174,710,332 (+)MAPPERmRatBN7.2
Rnor_6.04175,969,680 - 175,969,877NCBIRnor6.0
Rnor_5.04240,195,078 - 240,195,275UniSTSRnor5.0
Celera4163,247,170 - 163,247,367UniSTS
RH 3.4 Map41032.0UniSTS
Cytogenetic Map4q44UniSTS
AU046939  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24174,737,736 - 174,737,915 (+)MAPPERmRatBN7.2
Rnor_6.04175,998,460 - 175,998,638NCBIRnor6.0
Rnor_5.04240,223,858 - 240,224,036UniSTSRnor5.0
Celera4163,274,846 - 163,275,024UniSTS
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 4 8 106 57 63 34 79 34 6 204 100 3 90 56 87 29 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001439392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010065708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC144687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF041105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF083469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015112   ⟹   ENSRNOP00000015112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,903,330 - 176,937,886 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000049569   ⟹   ENSRNOP00000048288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,903,330 - 176,985,563 (-)Ensembl
Rnor_6.0 Ensembl4176,445,858 - 176,528,110 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110298   ⟹   ENSRNOP00000094123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,903,330 - 176,937,818 (-)Ensembl
RefSeq Acc Id: NM_030838   ⟹   NP_110465
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,388 - 176,963,812 (-)NCBI
mRatBN7.24175,172,390 - 175,232,822 (-)NCBI
Rnor_6.04176,445,924 - 176,506,352 (-)NCBI
Rnor_5.04240,660,960 - 240,741,922 (-)NCBI
RGSC_v3.44179,790,209 - 179,851,288 (-)RGD
Celera4163,705,427 - 163,765,715 (-)RGD
Sequence:
RefSeq Acc Id: XM_063286731   ⟹   XP_063142801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,985,585 (-)NCBI
RefSeq Acc Id: XM_063286732   ⟹   XP_063142802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,985,585 (-)NCBI
RefSeq Acc Id: XM_063286733   ⟹   XP_063142803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,985,585 (-)NCBI
RefSeq Acc Id: XM_063286734   ⟹   XP_063142804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,985,585 (-)NCBI
RefSeq Acc Id: XM_063286735   ⟹   XP_063142805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,985,585 (-)NCBI
RefSeq Acc Id: XM_063286736   ⟹   XP_063142806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,985,585 (-)NCBI
RefSeq Acc Id: XM_063286737   ⟹   XP_063142807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,903,387 - 176,919,978 (-)NCBI
RefSeq Acc Id: XR_010065708
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,910,510 - 176,985,589 (-)NCBI
RefSeq Acc Id: NP_110465   ⟸   NM_030838
- UniProtKB: Q9EQR8 (UniProtKB/Swiss-Prot),   O88397 (UniProtKB/Swiss-Prot),   A6IMT1 (UniProtKB/TrEMBL),   A0A8L2QP25 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048288   ⟸   ENSRNOT00000049569
RefSeq Acc Id: XP_063142806   ⟸   XM_063286736
- Peptide Label: isoform X1
- UniProtKB: Q9EQR8 (UniProtKB/Swiss-Prot),   O88397 (UniProtKB/Swiss-Prot),   A6IMT1 (UniProtKB/TrEMBL),   A0A8L2QP25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142802   ⟸   XM_063286732
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063142801   ⟸   XM_063286731
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063142804   ⟸   XM_063286734
- Peptide Label: isoform X1
- UniProtKB: Q9EQR8 (UniProtKB/Swiss-Prot),   O88397 (UniProtKB/Swiss-Prot),   A6IMT1 (UniProtKB/TrEMBL),   A0A8L2QP25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142805   ⟸   XM_063286735
- Peptide Label: isoform X1
- UniProtKB: Q9EQR8 (UniProtKB/Swiss-Prot),   O88397 (UniProtKB/Swiss-Prot),   A6IMT1 (UniProtKB/TrEMBL),   A0A8L2QP25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142803   ⟸   XM_063286733
- Peptide Label: isoform X1
- UniProtKB: Q9EQR8 (UniProtKB/Swiss-Prot),   O88397 (UniProtKB/Swiss-Prot),   A6IMT1 (UniProtKB/TrEMBL),   A0A8L2QP25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142807   ⟸   XM_063286737
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000015112   ⟸   ENSRNOT00000015112
Ensembl Acc Id: ENSRNOP00000094123   ⟸   ENSRNOT00000110298
Protein Domains
Kazal-like   Major facilitator superfamily (MFS) profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88397-F1-model_v2 AlphaFold O88397 1-670 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70985 AgrOrtholog
BioCyc Gene G2FUF-42500 BioCyc
Ensembl Genes ENSRNOG00000031249 Ensembl
  ENSRNOG00000047493 Ensembl
  ENSRNOG00000086993 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000015112 ENTREZGENE
  ENSRNOT00000049569 ENTREZGENE
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot
InterPro Kazal_dom UniProtKB/Swiss-Prot
  Kazal_dom_sf UniProtKB/Swiss-Prot
  MFS_dom UniProtKB/Swiss-Prot
  MFS_trans_sf UniProtKB/Swiss-Prot
  OATP UniProtKB/Swiss-Prot
KEGG Report rno:80900 UniProtKB/Swiss-Prot
NCBI Gene 80900 ENTREZGENE
PANTHER PTHR11388 UniProtKB/Swiss-Prot
  SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER-RELATED UniProtKB/Swiss-Prot
Pfam Kazal_2 UniProtKB/Swiss-Prot
  OATP UniProtKB/Swiss-Prot
PhenoGen Slco1a5 PhenoGen
PROSITE KAZAL_2 UniProtKB/Swiss-Prot
  MFS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031249 RatGTEx
  ENSRNOG00000047493 RatGTEx
  ENSRNOG00000086993 RatGTEx
Superfamily-SCOP SSF100895 UniProtKB/Swiss-Prot
  SSF103473 UniProtKB/Swiss-Prot
UniProt A0A8I6AKX8_RAT UniProtKB/TrEMBL
  A0A8L2Q774_RAT UniProtKB/TrEMBL
  A0A8L2QJT4_RAT UniProtKB/TrEMBL
  A0A8L2QP25 ENTREZGENE, UniProtKB/TrEMBL
  A6IMT1 ENTREZGENE, UniProtKB/TrEMBL
  O88397 ENTREZGENE
  Q9EQR8 ENTREZGENE
  SO1A5_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9EQR8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-17 Slco1a5  solute carrier organic anion transporter family, member 1A5  Slco1a2  solute carrier organic anion transporter family, member 1A2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Slco1a2  solute carrier organic anion transporter family, member 1A2  Slco1a5  solute carrier organic anion transporter family, member 1a5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Slco1a5  solute carrier organic anion transporter family, member 1a5  Slco1a2  solute carrier organic anion transporter family, member 1A2  Symbol and Name updated 1299863 APPROVED
2004-09-10 Slco1a2  solute carrier organic anion transporter family, member 1A2  Slco1a5  solute carrier organic anion transporter family, member 1a5  Symbol and Name updated 1299863 APPROVED
2004-01-09 Slco1a5  ssolute carrier organic anion transporter family, member 1a5  Slc21a7  solute carrier family 21 (fatty acid transporter), member 7  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-07-09 Slc21a7  solute carrier family 21 (fatty acid transporter), member 7      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA signals seen in the ganglion cells 70527
gene_expression present in the neuronal cells of the central nervous system and also in the optic nerve fiber 70527
gene_process transporter of thyroid hormones in the brain and retina 70527