Cdc5l (cell division cycle 5-like) - Rat Genome Database

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Gene: Cdc5l (cell division cycle 5-like) Rattus norvegicus
Analyze
Symbol: Cdc5l
Name: cell division cycle 5-like
RGD ID: 70892
Description: Enables enzyme binding activity; leucine zipper domain binding activity; and transcription corepressor binding activity. Involved in several processes, including cellular response to interleukin-2; cellular response to prolactin; and cellular response to wortmannin. Located in nuclear speck and perinuclear region of cytoplasm. Part of protein-DNA complex. Human ortholog(s) of this gene implicated in osteosarcoma. Orthologous to human CDC5L (cell division cycle 5 like); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 3-chloropropane-1,2-diol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CDC5 (cell division cycle 5 S. pombe homolog)-like; CDC5 (cell division cycle 5, S. pombe, homolog)-like; CDC5 cell division cycle 5-like; CDC5 cell division cycle 5-like (S. pombe); cdc5-like protein; cell division cycle 5-like (S. pombe); cell division cycle 5-like protein; cell division cycle 5-related protein; pombe Cdc5-related protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8923,062,397 - 23,100,901 (+)NCBIGRCr8
mRatBN7.2915,564,949 - 15,603,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,564,767 - 15,603,450 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,151,506 - 24,189,633 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,214,190 - 29,252,317 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,514,951 - 27,553,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,949,764 - 17,988,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,949,764 - 17,988,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,838,171 - 16,876,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,165,631 - 11,204,135 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,162,952 - 11,201,455 (+)NCBI
Celera913,308,462 - 13,346,957 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas. Bonner AE, etal., Oncogene. 2004 Feb 5;23(5):1166-76.
2. NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry. Boudrez A, etal., J Biol Chem. 2000 Aug 18;275(33):25411-7.
3. Splicing and beyond: the many faces of the Prp19 complex. Chanarat S and Strasser K, Biochim Biophys Acta. 2013 Oct;1833(10):2126-34. doi: 10.1016/j.bbamcr.2013.05.023. Epub 2013 Jun 3.
4. DAP-like kinase interacts with the rat homolog of Schizosaccharomyces pombe CDC5 protein, a factor involved in pre-mRNA splicing and required for G2/M phase transition. Engemann H, etal., Nucleic Acids Res 2002 Mar 15;30(6):1408-17.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target. Hansel DE, etal., Am J Surg Pathol. 2005 Mar;29(3):390-9.
7. Prolactin, interleukin-2 and FGF-2 stimulate expression, nuclear distribution and DNA-binding of rat homolog of pombe Cdc5 in Nb2 T lymphoma cells. Johnson LM and Too CK, Mol Cell Endocrinol. 2001 Nov 26;184(1-2):151-61.
8. Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma. Lu XY, etal., Mol Cancer Res. 2008 Jun;6(6):937-46. doi: 10.1158/1541-7786.MCR-07-2115.
9. Gene Data Set MGD Curation, June 12, 2002
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Differential expression of elongation factor-2, alpha4 phosphoprotein and Cdc5-like protein in prolactin-dependent/independent rat lymphoid cells. Too CK Mol Cell Endocrinol 1997 Aug 8;131(2):221-32.
17. Involvement of the mouse Prp19 gene in neuronal/astroglial cell fate decisions. Urano Y, etal., J Biol Chem. 2006 Mar 17;281(11):7498-514. Epub 2005 Dec 13.
18. Implication of Akt-dependent Prp19 alpha/14-3-3beta/Cdc5L complex formation in neuronal differentiation. Urano-Tashiro Y, etal., J Neurosci Res. 2010 Oct;88(13):2787-97. doi: 10.1002/jnr.22455.
Additional References at PubMed
PMID:9038199   PMID:11082045   PMID:11991638   PMID:12477932   PMID:16332694   PMID:19946888   PMID:20176811   PMID:22681889   PMID:24332808   PMID:28076346  


Genomics

Comparative Map Data
Cdc5l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8923,062,397 - 23,100,901 (+)NCBIGRCr8
mRatBN7.2915,564,949 - 15,603,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,564,767 - 15,603,450 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,151,506 - 24,189,633 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,214,190 - 29,252,317 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,514,951 - 27,553,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,949,764 - 17,988,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,949,764 - 17,988,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,838,171 - 16,876,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,165,631 - 11,204,135 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,162,952 - 11,201,455 (+)NCBI
Celera913,308,462 - 13,346,957 (+)NCBICelera
Cytogenetic Map9q12NCBI
CDC5L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,387,706 - 44,450,425 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,387,706 - 44,450,425 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,355,443 - 44,418,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,463,280 - 44,522,758 (+)NCBINCBI36Build 36hg18NCBI36
Build 34644,463,279 - 44,522,757NCBI
Celera645,908,480 - 45,967,835 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef644,077,869 - 44,140,670 (+)NCBIHuRef
CHM1_1644,358,890 - 44,421,686 (+)NCBICHM1_1
T2T-CHM13v2.0644,222,452 - 44,285,059 (+)NCBIT2T-CHM13v2.0
Cdc5l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,702,809 - 45,744,633 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,702,810 - 45,744,663 (-)EnsemblGRCm39 Ensembl
GRCm381745,391,887 - 45,433,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,391,884 - 45,433,737 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,528,836 - 45,570,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361744,855,468 - 44,897,288 (-)NCBIMGSCv36mm8
Celera1748,822,530 - 48,866,019 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.36NCBI
Cdc5l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,990,613 - 10,032,034 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,990,613 - 10,032,034 (+)NCBIChiLan1.0ChiLan1.0
CDC5L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,891,113 - 58,955,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,761,126 - 54,821,533 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,983,840 - 44,043,029 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,265,845 - 45,326,392 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,265,845 - 45,326,383 (+)Ensemblpanpan1.1panPan2
CDC5L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,779,936 - 12,822,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,780,010 - 12,822,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,807,973 - 12,851,031 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,266,108 - 13,309,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,266,132 - 13,309,158 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,791,651 - 12,835,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,879,429 - 12,922,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,973,455 - 13,016,504 (+)NCBIUU_Cfam_GSD_1.0
Cdc5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,262,000 - 48,311,662 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,648,678 - 15,698,106 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,647,470 - 15,698,095 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC5L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,384,556 - 39,431,248 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,384,397 - 39,427,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,306,065 - 45,349,669 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC5L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,727,185 - 27,785,233 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,722,819 - 27,785,268 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,437,105 - 44,495,930 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc5l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,477,193 - 15,517,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,477,188 - 15,517,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdc5l
282 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:45
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000027264
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat

Markers in Region
RH125755  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2915,603,111 - 15,603,365 (+)MAPPERmRatBN7.2
Rnor_6.0917,988,173 - 17,988,426NCBIRnor6.0
Rnor_5.0916,876,580 - 16,876,833UniSTSRnor5.0
RGSC_v3.4911,203,794 - 11,204,047UniSTSRGSC3.4
Celera913,346,616 - 13,346,869UniSTS
Cytogenetic Map9q12UniSTS
RH131317  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2915,603,052 - 15,603,233 (+)MAPPERmRatBN7.2
Rnor_6.0917,988,114 - 17,988,294NCBIRnor6.0
Rnor_5.0916,876,521 - 16,876,701UniSTSRnor5.0
RGSC_v3.4911,203,735 - 11,203,915UniSTSRGSC3.4
Celera913,346,557 - 13,346,737UniSTS
RH 3.4 Map978.6UniSTS
Cytogenetic Map9q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000027264   ⟹   ENSRNOP00000027264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl915,564,767 - 15,603,450 (+)Ensembl
Rnor_6.0 Ensembl917,949,764 - 17,988,509 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112966   ⟹   ENSRNOP00000079717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl915,564,767 - 15,591,798 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120250   ⟹   ENSRNOP00000087958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl915,566,784 - 15,603,450 (+)Ensembl
RefSeq Acc Id: NM_053527   ⟹   NP_445979
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8923,062,397 - 23,100,899 (+)NCBI
mRatBN7.2915,564,949 - 15,603,453 (+)NCBI
Rnor_6.0917,949,764 - 17,988,514 (+)NCBI
Rnor_5.0916,838,171 - 16,876,921 (+)NCBI
RGSC_v3.4911,165,631 - 11,204,135 (+)RGD
Celera913,308,462 - 13,346,957 (+)RGD
Sequence:
RefSeq Acc Id: XM_063267788   ⟹   XP_063123858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8923,080,080 - 23,100,901 (+)NCBI
RefSeq Acc Id: NP_445979   ⟸   NM_053527
- UniProtKB: O08837 (UniProtKB/Swiss-Prot),   B1WBQ0 (UniProtKB/TrEMBL),   A0A8I6A562 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027264   ⟸   ENSRNOT00000027264
Ensembl Acc Id: ENSRNOP00000079717   ⟸   ENSRNOT00000112966
Ensembl Acc Id: ENSRNOP00000087958   ⟸   ENSRNOT00000120250
RefSeq Acc Id: XP_063123858   ⟸   XM_063267788
- Peptide Label: isoform X1
Protein Domains
HTH myb-type   Myb-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08837-F1-model_v2 AlphaFold O08837 1-802 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696548
Promoter ID:EPDNEW_R7072
Type:multiple initiation site
Name:Cdc5l_1
Description:cell division cycle 5-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0917,949,752 - 17,949,812EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70892 AgrOrtholog
BioCyc Gene G2FUF-28161 BioCyc
Ensembl Genes ENSRNOG00000019975 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055007576 UniProtKB/Swiss-Prot
  ENSRNOG00060020516 UniProtKB/Swiss-Prot
  ENSRNOG00065026122 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027264.5 UniProtKB/Swiss-Prot
  ENSRNOT00000112966.1 UniProtKB/TrEMBL
  ENSRNOT00000120250.1 UniProtKB/TrEMBL
  ENSRNOT00055012680 UniProtKB/Swiss-Prot
  ENSRNOT00060035789 UniProtKB/Swiss-Prot
  ENSRNOT00065045110 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125496 IMAGE-MGC_LOAD
  IMAGE:9101355 IMAGE-MGC_LOAD
InterPro CDC5L/Cef1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc5p/Cef1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myb_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SANT/Myb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SANT_CDC5L_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:85434 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:187349 IMAGE-MGC_LOAD
  MGC:93301 IMAGE-MGC_LOAD
NCBI Gene 85434 ENTREZGENE
PANTHER CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/Swiss-Prot
  CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/Swiss-Prot
  CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/TrEMBL
  CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Myb_Cef UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myb_DNA-bind_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdc5l PhenoGen
PROSITE HTH_MYB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYB_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019975 RatGTEx
  ENSRNOG00055007576 RatGTEx
  ENSRNOG00060020516 RatGTEx
  ENSRNOG00065026122 RatGTEx
SMART SANT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZNY5_RAT UniProtKB/TrEMBL
  A0A8I6A562 ENTREZGENE, UniProtKB/TrEMBL
  B1WBQ0 ENTREZGENE, UniProtKB/TrEMBL
  CDC5L_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-23 Cdc5l  cell division cycle 5-like  Cdc5l  CDC5 cell division cycle 5-like (S. pombe)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Cdc5l  CDC5 cell division cycle 5-like (S. pombe)  Cdc5l  cell division cycle 5-like (S. pombe)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Cdc5l  cell division cycle 5-like (S. pombe)      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds the leucine zipper domain of DAP-like kinase (Dlk), binding occurs via the Cdc5l C-terminal region between residues 500 and 802 619664
gene_regulation differential display shows transcription upregulated by prolactin 61637