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Gene: Cadps (calcium dependent secretion activator) Rattus norvegicus

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Symbol:

Cadps

Name:

calcium dependent secretion activator

RGD ID:

708573

Description:

Enables calcium ion binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in calcium-ion regulated exocytosis and positive regulation of dense core granule exocytosis. Located in cytosol and dense core granule. Is active in glutamatergic synapse and presynapse. Is extrinsic component of neuronal dense core vesicle membrane. Orthologous to human CADPS (calcium dependent secretion activator); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Ca++-dependent secretion activator; Ca2+ dependent secretion activator; Ca2+-dependent activator protein; Ca2+-dependent secretion activator; Ca<2+-dependent activator protein for secretion; calcium-dependent activator protein for secretion 1; calcium-dependent secretion activator 1; calcium-dependent secretion activator 1-like; Caps; CAPS-1; Caps1; Caps2; LOC103690082; rCAPS

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CADPS (calcium dependent secretion activator)	HGNC	Ensembl, HomoloGene, Inparanoid, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Cadps (Ca2+-dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cadps (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CADPS (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CADPS (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cadps (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CADPS (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CADPS (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cadps (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cadps (calcium dependent secretion activator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DEDD (death effector domain containing)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Cadps (Ca2+-dependent secretion activator)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CADPS (calcium dependent secretion activator)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cadpsa (Ca2+-dependent activator protein for secretion a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cadpsa (Ca2+-dependent activator protein for secretion a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cadpsb (Ca2+-dependent activator protein for secretion b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Cadps	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Cadps	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-31	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cadps	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cadps	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Candidate Gene For:

Kidm51

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl				GRCr8
mRatBN7.2	15	12,289,803 - 12,742,786 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	14,405,013 - 14,871,376 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	15,363,441 - 15,829,833 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	13,618,231 - 14,084,627 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	15,275,489 - 15,690,575 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	15,275,541 - 15,667,778 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	19,278,581 - 19,669,176 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	15	16,777,584 - 16,823,679 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	13,859,286 - 14,319,814 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	12,289,818 - 12,740,628 (+)	NCBI		Celera
RGSC_v3.1	15	13,859,285 - 14,319,814 (+)	NCBI
Cytogenetic Map	15	p15	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

arsenite(3-) (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP)

cadmium atom (ISO)

choline (ISO)

copper atom (EXP)

copper(0) (EXP)

DDT (EXP)

dibutyl phthalate (EXP)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dorsomorphin (ISO)

ethanol (ISO)

fenamidone (ISO)

folic acid (ISO)

furan (EXP)

ivermectin (ISO)

L-methionine (ISO)

lead(0) (ISO)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenobarbital (EXP)

phenylephrine (EXP)

pirinixic acid (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

succimer (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (EXP)

zinc sulfate (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium-ion regulated exocytosis (IMP)

catecholamine secretion (ISO)

dense core granule exocytosis (IEA)

exocytosis (IBA,IEA)

neuronal dense core vesicle exocytosis (IMP)

positive regulation of exocytosis (IBA,IMP)

presynaptic dense core vesicle exocytosis (IEA,ISO)

protein transport (IEA)

regulated exocytosis (IEA,TAS)

synaptic vesicle exocytosis (IEA)

synaptic vesicle priming (IEA,ISO)

vesicle organization (ISO)

Cellular Component

cytoplasmic vesicle (IEA,ISO)

cytoplasmic vesicle membrane (IEA)

cytosol (IDA)

dense core granule (IDA)

extrinsic component of neuronal dense core vesicle membrane (IDA,IEP)

glutamatergic synapse (IBA,IDA,IEA,IEP,ISO)

neuronal dense core vesicle membrane (IEA)

presynapse (IDA,IEA,IEP)

synapse (IEA)

Molecular Function

calcium ion binding (IDA)

lipid binding (IEA)

metal ion binding (IEA)

phosphatidylinositol-4,5-bisphosphate binding (IDA,TAS)

protein binding (IPI,ISO)

protein kinase binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Novel Ca2+-binding protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis.	Ann K, etal., J Biol Chem 1997 Aug 8;272(32):19637-40.
2.	CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis.	Berwin B, etal., Neuron. 1998 Jul;21(1):137-45.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	CAPS drives trans-SNARE complex formation and membrane fusion through syntaxin interactions.	James DJ, etal., Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17308-13. doi: 10.1073/pnas.0900755106. Epub 2009 Sep 29.
5.	CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis.	Kabachinski G, etal., Mol Biol Cell. 2014 Feb;25(4):508-21. doi: 10.1091/mbc.E12-11-0829. Epub 2013 Dec 19.
6.	Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis.	Loyet KM, etal., J Biol Chem. 1998 Apr 3;273(14):8337-43.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function.	Speidel D, etal., J Biol Chem. 2003 Dec 26;278(52):52802-9. doi: 10.1074/jbc.M304727200. Epub 2003 Oct 6.
12.	A novel 145 kd brain cytosolic protein reconstitutes Ca(2+)-regulated secretion in permeable neuroendocrine cells.	Walent JH, etal., Cell 1992 Sep 4;70(5):765-75.
13.	Role of CAPS in dense-core vesicle exocytosis.	Wassenberg JJ and Martin TF, Ann N Y Acad Sci 2002 Oct;971:201-9.
14.	Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.	Zhou H, etal., Cell Rep. 2019 Mar 19;26(12):3347-3359.e6. doi: 10.1016/j.celrep.2019.02.064.

Additional References at PubMed

PMID:9162085	PMID:9697859	PMID:10792045	PMID:11927595	PMID:15312653	PMID:15820695	PMID:15857609	PMID:15866726	PMID:17540763	PMID:18022372	PMID:19008227	PMID:19460754
PMID:19896969	PMID:20826818	PMID:20921225	PMID:21040848	PMID:21307259	PMID:21803295	PMID:23801330	PMID:25374362	PMID:25719439	PMID:26700319	PMID:27528604	PMID:28131823
PMID:29476059	PMID:30053369	PMID:33580180

Genomics

Comparative Map Data

Cadps
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl				GRCr8
mRatBN7.2	15	12,289,803 - 12,742,786 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	14,405,013 - 14,871,376 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	15,363,441 - 15,829,833 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	13,618,231 - 14,084,627 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	15,275,489 - 15,690,575 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	15,275,541 - 15,667,778 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	19,278,581 - 19,669,176 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	15	16,777,584 - 16,823,679 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	13,859,286 - 14,319,814 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	12,289,818 - 12,740,628 (+)	NCBI		Celera
RGSC_v3.1	15	13,859,285 - 14,319,814 (+)	NCBI
Cytogenetic Map	15	p15	NCBI

CADPS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	62,398,348 - 62,875,416 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	62,398,346 - 62,875,563 (-)	Ensembl			hg38	GRCh38
GRCh37	3	62,384,023 - 62,861,091 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	62,359,061 - 62,836,094 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	62,359,061 - 62,836,094	NCBI
Celera	3	62,401,123 - 62,879,063 (-)	NCBI		Celera
Cytogenetic Map	3	p14.2	NCBI
HuRef	3	62,482,129 - 62,959,100 (-)	NCBI		HuRef
CHM1_1	3	62,335,136 - 62,812,174 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	62,441,892 - 62,919,090 (-)	NCBI		T2T-CHM13v2.0

Cadps
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	9,646,424 - 10,097,203 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	9,646,684 - 10,097,200 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	12,372,560 - 12,823,339 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	12,372,563 - 12,823,079 (-)	Ensembl			mm10	GRCm38
MGSCv37	14	13,205,077 - 13,655,593 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	11,165,830 - 11,616,320 (-)	NCBI		MGSCv36	mm8
Celera	14	8,001,668 - 8,456,520 (-)	NCBI		Celera
Cytogenetic Map	14	A1	NCBI
cM Map	14	6.37	NCBI

Cadps
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955517	2,966,679 - 3,419,126 (+)	Ensembl
ChiLan1.0	NW_004955517	2,965,471 - 3,420,183 (+)	NCBI	ChiLan1.0	ChiLan1.0

CADPS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	62,342,099 - 62,817,146 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	62,346,887 - 62,821,881 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	62,321,496 - 62,797,298 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	63,708,293 - 64,181,768 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

CADPS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	28,221,150 - 28,680,844 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	28,221,843 - 28,680,131 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	28,144,566 - 28,609,081 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	28,444,589 - 28,915,736 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	28,444,992 - 28,915,733 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	27,941,382 - 28,401,452 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	28,298,223 - 28,759,372 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	28,394,230 - 28,859,360 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cadps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	165,154,804 - 165,634,154 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936637	3,545,211 - 4,022,630 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936637	3,543,615 - 4,023,710 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CADPS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	13	43,979,694 - 44,482,985 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	48,085,695 - 48,367,520 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CADPS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	23,471,616 - 23,948,694 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666041	142,910,744 - 143,393,718 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cadps
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624888	2,985,966 - 3,443,542 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cadps
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	82,442,605 - 82,885,244 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cadps
2565 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	170
Count of miRNA genes:	123
Interacting mature miRNAs:	136
Transcripts:	ENSRNOT00000012153
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	32342855	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
1300142	Bp191	Blood pressure QTL 191	3.14		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	15	1	15177511	Rat

Markers in Region

D15Rat54

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	14,926,594 - 14,926,817 (+)	Marker Load Pipeline
mRatBN7.2	15	12,496,141 - 12,496,364 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,492,360 - 15,492,582	NCBI	Rnor6.0
Rnor_5.0	15	19,494,318 - 19,494,540	UniSTS	Rnor5.0
RGSC_v3.4	15	14,072,030 - 14,072,252	UniSTS	RGSC3.4
RGSC_v3.4	15	14,072,029 - 14,072,252	RGD	RGSC3.4
Celera	15	12,495,261 - 12,495,483	UniSTS
RGSC_v3.1	15	14,072,030 - 14,072,252	RGD
RH 3.4 Map	15	103.3	UniSTS
RH 3.4 Map	15	103.3	RGD
RH 2.0 Map	15	43.8	RGD
SHRSP x BN Map	15	9.5998	RGD
FHH x ACI Map	15	8.0599	UniSTS
FHH x ACI Map	15	8.0199	RGD
Cytogenetic Map	15	p16	UniSTS

D15Rat159

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	15	19,494,317 - 19,494,540	NCBI	Rnor5.0
RGSC_v3.4	15	14,072,030 - 14,072,252	UniSTS	RGSC3.4
Celera	15	12,495,261 - 12,495,483	UniSTS
RGSC_v3.1	15	14,072,029 - 14,072,252	RGD
RH 3.4 Map	15	103.3	UniSTS
FHH x ACI Map	15	8.0599	RGD

D15Rat137

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	14,775,892 - 14,776,045 (+)	Marker Load Pipeline
mRatBN7.2	15	12,345,430 - 12,345,585 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,330,772 - 15,330,924	NCBI	Rnor6.0
Rnor_5.0	15	19,333,571 - 19,333,723	UniSTS	Rnor5.0
RGSC_v3.4	15	13,915,114 - 13,915,266	UniSTS	RGSC3.4
RGSC_v3.4	15	13,915,113 - 13,915,266	RGD	RGSC3.4
Celera	15	12,344,951 - 12,345,103	UniSTS
RGSC_v3.1	15	13,915,113 - 13,915,266	RGD
SHRSP x BN Map	15	9.5698	RGD
SHRSP x BN Map	15	9.5698	UniSTS
Cytogenetic Map	15	p16	UniSTS

BF388496

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,624,913 - 12,625,084 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,620,473 - 15,620,643	NCBI	Rnor6.0
Rnor_5.0	15	19,622,093 - 19,622,263	UniSTS	Rnor5.0
RGSC_v3.4	15	14,200,391 - 14,200,561	UniSTS	RGSC3.4
Celera	15	12,622,841 - 12,623,011	UniSTS
RH 3.4 Map	15	95.4	UniSTS
Cytogenetic Map	15	p16	UniSTS

RH134048

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,372,228 - 12,372,410 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,357,873 - 15,358,054	NCBI	Rnor6.0
Rnor_5.0	15	19,360,381 - 19,360,562	UniSTS	Rnor5.0
RGSC_v3.4	15	13,945,942 - 13,946,123	UniSTS	RGSC3.4
Celera	15	12,371,725 - 12,371,906	UniSTS
RH 3.4 Map	15	96.6	UniSTS
Cytogenetic Map	15	p16	UniSTS

BF388503

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,720,057 - 12,720,192 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	12,773,740 - 12,773,874	NCBI	Rnor6.0
Rnor_5.0	15	16,800,959 - 16,801,093	UniSTS	Rnor5.0
RGSC_v3.4	15	14,297,094 - 14,297,228	UniSTS	RGSC3.4
Celera	15	12,717,901 - 12,718,035	UniSTS
RH 3.4 Map	15	95.8	UniSTS
Cytogenetic Map	15	p16	UniSTS

AU048310

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,527,434 - 12,527,551 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,523,610 - 15,523,726	NCBI	Rnor6.0
Rnor_5.0	15	19,525,568 - 19,525,684	UniSTS	Rnor5.0
RGSC_v3.4	15	14,103,287 - 14,103,403	UniSTS	RGSC3.4
Celera	15	12,526,110 - 12,526,226	UniSTS
Cytogenetic Map	15	p16	UniSTS

RH135013

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,741,868 - 12,742,083 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	12,795,550 - 12,795,764	NCBI	Rnor6.0
Rnor_5.0	15	16,822,769 - 16,822,983	UniSTS	Rnor5.0
RGSC_v3.4	15	14,318,904 - 14,319,118	UniSTS	RGSC3.4
Celera	15	12,739,718 - 12,739,932	UniSTS
RH 3.4 Map	15	99.0	UniSTS
Cytogenetic Map	15	p16	UniSTS

RH136728

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	15,172,842 - 15,173,080 (+)	Marker Load Pipeline
mRatBN7.2	15	12,742,410 - 12,742,648 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	12,796,092 - 12,796,329	NCBI	Rnor6.0
Rnor_5.0	15	16,823,311 - 16,823,548	UniSTS	Rnor5.0
RGSC_v3.4	15	14,319,446 - 14,319,683	UniSTS	RGSC3.4
Celera	15	12,740,260 - 12,740,497	UniSTS
RH 3.4 Map	15	110.0	UniSTS
Cytogenetic Map	15	p16	UniSTS

RH138000

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,605,556 - 12,605,705 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,601,116 - 15,601,264	NCBI	Rnor6.0
Rnor_5.0	15	19,602,736 - 19,602,884	UniSTS	Rnor5.0
RGSC_v3.4	15	14,181,034 - 14,181,182	UniSTS	RGSC3.4
Celera	15	12,603,472 - 12,603,620	UniSTS
RH 3.4 Map	15	95.2	UniSTS
Cytogenetic Map	15	p16	UniSTS

AW531782

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	12,288,885 - 12,289,050 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	15,274,113 - 15,274,277	NCBI	Rnor6.0
Rnor_5.0	15	19,277,205 - 19,277,369	UniSTS	Rnor5.0
RGSC_v3.4	15	13,857,907 - 13,858,071	UniSTS	RGSC3.4
Celera	15	12,288,442 - 12,288,606	UniSTS
RH 3.4 Map	15	97.8	UniSTS
Cytogenetic Map	15	p16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	9	66	156	82	80	50	40	50	6	284	132	7	132	78	92	30	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_013219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U16802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000012153 ⟹ ENSRNOP00000012153

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl
Rnor_6.0 Ensembl	15	15,275,541 - 15,667,778 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094744 ⟹ ENSRNOP00000076873

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	14,720,726 - 15,173,199 (+)	Ensembl
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094787 ⟹ ENSRNOP00000095628

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098925 ⟹ ENSRNOP00000092113

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099157 ⟹ ENSRNOP00000095354

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105737 ⟹ ENSRNOP00000093742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115067 ⟹ ENSRNOP00000086566

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	14,720,726 - 15,173,211 (+)	Ensembl
mRatBN7.2 Ensembl	15	12,290,262 - 12,742,779 (+)	Ensembl

RefSeq Acc Id:

NM_013219 ⟹ NP_037351

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,720,726 - 15,173,211 (+)	NCBI
mRatBN7.2	15	12,290,262 - 12,742,779 (+)	NCBI
Rnor_6.0	15	15,275,489 - 15,690,575 (+)	NCBI
Rnor_5.0	15	16,777,584 - 16,823,679 (+)	NCBI
Rnor_5.0	15	19,278,581 - 19,669,176 (+)	NCBI
RGSC_v3.4	15	13,859,286 - 14,319,814 (+)	RGD
Celera	15	12,289,818 - 12,740,628 (+)	RGD

Sequence:

show sequence

GAATTCCGGTTTTGCACCCCAAGCCGAGGACTCCGGGGACCCTCCTCTCCCAGGCGCCACCATG
CTGGACCCTTCGTCCAGCGAAGAGGAATCGGATGAGATCCTGGAAGAGGAGAGCGGCAAGGAGG
TGCTGGGCTCGGCCGCGTCCGGAGCGCGCCTGTCTCCAAGCCGCACCAACGAGGGCTCGGCGGG
CAGCGCCGGCATGGGGGGCAGTGGCGCCGGGGCCGGGGTGGGCGCCGGCGGCGGTGGGGGTAGC
GGCGCGAGCAGCGGCGGCGGGGCCGGGGGGCTGCAGCCCAGCAGCCGCGCCGGCGGCGGCCGGC
CCTCCAGCCCCAGCCCGTCGGTGGTGAGCGAGAAGGAGAAGGAAGAGTTGGAGCGGCTGCAGAA
GGAAGAGGAGGAGAGGAAGAAGAGGCTGCAGCTGTACGTGTTCGTGATGCGCTGCATTGCCTAC
CCCTTCAACGCCAAGCAGCCCACCGACATGGCTCGGCGGCCAAGGAAGATCAGCAAACAGCAGC
TGCAGACTGTCAAGGACCGATTCCAGGCTTTCCTCAATGGGGAGACCCAAATCGTGGCAGATGA
AGCCTTTATGAATGCTGTCCAGAGCTACTATGAGGTGTTTCTCAAGAGTGACCGTGTGGCCCGC
ATGGTACAGAGTGGGGGCTGCTCAGCCAACGACTCTCGGGAGGTCTTCAAGAAACACATCGAGA
AGAGGGTACGCAGCCTACCTGAGATTGATGGCCTCAGCAAGGAGACTGTGCTAAGCTCCTGGAT
GGCTAAGTTTGACGCCATCTACCGTGGTGAGGAGGACCCCAGGAAGCAGCAAGCCCGGATGACA
GCCAGTGCAGCTTCTGAGTTGATTCTGAGCAAGGAACAGCTCTATGAGATGTTCCAGAACATTC
TTGGGATCAAGAAATTTGAACATCAACTCCTATATAATGCGTGTCAGCTGGACAATCCAGATGA
GCAGGCAGCCCAGATCAGACGAGAGCTGGACGGACGTCTCCAAATGGCAGACCAAATAGCCAGG
GAACGCAAATTTCCTAAGTTCGTATCCAAAGAAATGGAAAATATGTACATCGAGGAGCTGAAGT
CCTCCGTCAACCTACTCATGGCCAACTTGGAGAGCATGCCGGTGTCCAAGGGTGGAGAGTTCAA
GCTGCAGAAACTGAAACGCAGTCACAACGCGTCCATCATTGACATGGGTGAGGAGAGCGAGAAC
CAGCTGTCCAAGTCGGATGTCCTGCTGTCCTTCTCCTTGGAGGTTGTCATCATGGAAGTCCAAG
GCCTTAAGTCCTTGGCTCCAAACCGAATCGTGTACTGCACAATGGAGGTGGAGGGTGGAGAGAA
ACTTCAGACTGATCAAGCAGAGGCTTCTAAACCAACCTGGGGCACTCAAGGCGACTTCTCTACA
ACCCACGCGCTGCCAGCTGTTAAAGTAAAGCTATTCACAGAGAGCACTGGTGTCCTGGCCTTGG
AAGACAAGGAACTCGGGCGGGTTATCCTCCATCCCACCCCAAACAGCCCCAAACAATCCGAGTG
GCACAAAATGACAGTCTCCAAAAACTGCCCCGATCAAGACCTCAAAATCAAACTCGCTGTCCGA
ATGGATAAGCCTCAAAACATGAAGCACTCTGGGTACTTATGGACCATTGGTAAGAATGTGTGGA
AGAGGTGGAAGAAAAGGTTCTTTGTGTTGGTGCAGGTCAGCCAGTACACTTTTGCCATGTGCAG
CTATCGAGAAAAGAAAGCAGAACCTCAGGAACTCCTACAGCTGGATGGCTACACCGTGGATTAC
ACCGACCCTCAGCCAGGTTTGGAGGGTGGCCGAGCCTTCTTCAATGCAGTCAAAGAAGGAGACA
CGGTGATATTTGCCAGTGACGATGAGCAAGATCGAATCCTGTGGGTCCAAGCTATGTACAGGGC
CACCGGGCAGTCGCACAAACCTGTGCCCCCTACCCAGGTGCAGAAGCTCAAGCCAAGGGCGGAA
ACGTGCCTCAGCATGGATGCCCCCATCTCCCAGTTTTACGCAGATAGAGCTCAAAAGCATGGCA
TGGATGAATTTATCTCGTCCAACCCCTGTAACTTTGACCACGCTTCCCTCTTTGAGATGGTACA
GCGGCTGACTTTGGATCACAGACTAAACGATTCCTATTCTTGCCTGGGCTGGTTCAGTCCTGGC
CAGGTGTTTGTGTTAGACGAGTACTGCGCTCGGAATGGAGTCCGAGGATGTCATCGGCATCTCT
GTTACCTTAGAGACTTGCTGGAACGGGCAGAAAATGGCGCCATGATCGACCCCACGCTTCTTCA
TTACAGCTTTGCCTTCTGCGCATCCCATGTCCACGGGAACAGGCCTGATGGAATCGGAACTGTG
ACTGTTGAAGAAAAAGAGCGCTTTGAAGAAATCAAAGAGAGACTCCGAGTTCTGCTGGAAAATC
AAATTACACATTTCAGGTACTGCTTTCCGTTTGGTCGACCTGAAGGTGCTTTGAAAGCGACTCT
CTCACTTTTGGAACGGGTTTTGATGAAAGATATTGTCACTCCAGTACCCCAAGAGGAGGTCAAA
ACTGTCATCCGTAAATGCCTAGAGCAGGCTGCTCTAGTCAACTACTCTCGCCTATCTGAGTATG
CCAAAATCGAAGAAAATGTAGGCCGCTTAATCACTCCCGCCAAAAAGCTCGAAGACACAATCCG
TCTTGCTGAACTAGTCATTGAAGTGCTGCAACAAAACGAAGAGCACCACGCCGAGGCCTTTGCG
TGGTGGTCAGACTTAATGGTGGAGCACGCGGAGACGTTCCTGTCACTCTTTGCAGTGGACATGG
ATGCAGCATTAGAGGTGCAACCCCCAGACACGTGGGACAGTTTCCCACTCTTCCAGCTGCTGAA
TGACTTTCTCCGTACAGACTATAACTTGTGCAATGGAAAGTTTCACAAACACCTGCAGGATCTG
TTCGCCCCACTCGTTGTTAGATACGTGGATCTGATGGAGTCCTCAATTGCACAATCTATCCACA
GGGGCTTTGAGCGGGAGTCATGGGAACCAGTCAATAACGGATCGGGTACATCAGAAGATTTGTT
CTGGAAACTTGATGCCCTTCAGACTTTCATCCGTGACCTACACTGGCCTGAGGAAGAGTTTGGA
AAGCACTTAGAGCAGCGGCTAAAACTAATGGCAAGCGACATGATTGAGTCCTGCGTCAAGAGAA
CCAGGATTGCATTTGAAGTTAAGCTGCAAAAAACCAGTCGATCAACAGATTTTCGAGTCCCACA
GTCAATATGCACCATGTTTAATGTTATGGTTGATGCCAAAGCTCAATCAACAAAACTTTGCAGC
ATGGAAATGGGCCAGGAGCATCAATACCATTCAAAAATAGACGAACTAATTGAAGAAACCGTTA
AGGAAATGATCACACTCTTGGTGGCAAAGTTTGTAACTATATTGGAAGGCGTACTGGCAAAGTT
ATCCAGATACGACGAGGGGACTTTGTTTTCTTCGTTTCTGTCATTTACGGTGAAGGCGGCATCT
AAGTATGTGGACGTACCTAAACCCGGGATGGATGTGGCCGACGCCTACGTGACTTTCGTCCGCC
ACTCTCAGGATGTCCTTCGTGATAAGGTCAATGAGGAGATGTATATAGAAAGGTTATTTGATCA
ATGGTACAACAGCTCCATGAACGTCATCTGCACCTGGCTGACCGACCGGATGGACCTCCAGCTT
CACATTTATCAGCTGAAAACACTAATTAGGATGGTAAAGAAAACCTACAGAGATTTCCGATTGC
AAGGGGTCCTGGATTCCACCTTAAACAGCAAGACCTATGAGACCATTCGAAATCGGCTCACTGT
AGAGGAACGTACCGCGTCCGTGAGTGAGGGAGGGGGCTTGCAAGGCATCAGCATGAAGGACAGT
GACGAGGAAGATGAAGAAGACGACTAGATCATTCTCTGGGTCCAAGAGTCCACTGGGATGGAGT
CCTGTAATCAATGCATGTCTTTAGTCTGTTAGTTAACCCCATTAGGGAATTTTCTGTCAACCAC
CATGCCCATGAGATGTTTACCAATACAGACACCATTTTAGCTGCGTGGTACCAAGATTAGCACA
TTGGTTTAATGCAAGACTGGCATTACCCAATTCTTAAACACAGTTCCATGGAGAGACACATAGT
TCAGCTGCTAGGTGTGTCCCTTTTGTTAGCAGAACAAAACGATGCTTCACCCTGTGCTCCGTAT
GTACTGATAGGAAGCAGACGTGGGAGCCAGTGTGTTTCCAAGTCTCTGTTTCACATATGTGGGT
ATCAGGTACTTAAATTAGTACATAAATAAATTAATTTAAGCACATAGATCTGCTTGGTTTTGGT
CTCCGTTTTGTTCTCATCCCCCGAAACTGAAAGCAATGGGCGTTTGTGTCCTGGCAAACACAGC
TTTGCATTTTTCCTTGTAGTTTCCCCCCACCACCAAAAAAGTTAATTATTGATTAACTTGGATT
AATAATAAAGTGAATTAATTATTTTAATTGTCATGGTCAAGGGGCCATGTGATCAGACGTAGCA
TCAAGCAAGGTTCAGACCAATTGTCTTCTGTGGAAGTTTATCCTAGTACATGTCACGTTTTCTG
TTTCAATAACTGTATATGTAAAAAAAAAGTATCGAAATGACAACCCTAGACTATAAATGTATTT
ATAATAAGATATGGATATCTCCTCCAGTAGACTGTAACCATGATTTCCATTATTTTGTTCCACA
CTGTTTTTATATCTGTCACGTACATTGCACTCTGATCTGTAACTGAGCGACCCTGGGGTCCTCT
GTAGAGCTGTTTCTTTCTGTGGAAAGTAGTGGATCCATCTTGCTTTTTGCCTTATATAAAAGCC
TACAGTTGTAAAAGTGTGGGGAACTGTGGCTTCTCAATAAACAATTATTCAAACGTCAAAAA

hide sequence

RefSeq Acc Id:

XM_039093050 ⟹ XP_038948978

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI
mRatBN7.2	15	12,290,314 - 12,741,766 (+)	NCBI

RefSeq Acc Id:

XM_039093055 ⟹ XP_038948983

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI
mRatBN7.2	15	12,290,314 - 12,741,766 (+)	NCBI

RefSeq Acc Id:

XM_039093060 ⟹ XP_038948988

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI
mRatBN7.2	15	12,290,314 - 12,741,766 (+)	NCBI

RefSeq Acc Id:

XM_039093064 ⟹ XP_038948992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI
mRatBN7.2	15	12,290,314 - 12,741,766 (+)	NCBI

RefSeq Acc Id:

XM_039093067 ⟹ XP_038948995

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI
mRatBN7.2	15	12,290,314 - 12,741,766 (+)	NCBI

RefSeq Acc Id:

XM_039093071 ⟹ XP_038948999

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI
mRatBN7.2	15	12,289,803 - 12,742,786 (+)	NCBI

RefSeq Acc Id:

XM_063274046 ⟹ XP_063130116

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274048 ⟹ XP_063130118

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274049 ⟹ XP_063130119

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274050 ⟹ XP_063130120

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274051 ⟹ XP_063130121

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274052 ⟹ XP_063130122

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274054 ⟹ XP_063130124

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,173,218 (+)	NCBI

RefSeq Acc Id:

XM_063274055 ⟹ XP_063130125

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 15,032,985 (+)	NCBI

RefSeq Acc Id:

XM_063274056 ⟹ XP_063130126

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	14,719,078 - 14,976,244 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_037351	(Get FASTA)	NCBI Sequence Viewer
	XP_038948978	(Get FASTA)	NCBI Sequence Viewer
	XP_038948983	(Get FASTA)	NCBI Sequence Viewer
	XP_038948988	(Get FASTA)	NCBI Sequence Viewer
	XP_038948992	(Get FASTA)	NCBI Sequence Viewer
	XP_038948995	(Get FASTA)	NCBI Sequence Viewer
	XP_038948999	(Get FASTA)	NCBI Sequence Viewer
	XP_063130116	(Get FASTA)	NCBI Sequence Viewer
	XP_063130118	(Get FASTA)	NCBI Sequence Viewer
	XP_063130119	(Get FASTA)	NCBI Sequence Viewer
	XP_063130120	(Get FASTA)	NCBI Sequence Viewer
	XP_063130121	(Get FASTA)	NCBI Sequence Viewer
	XP_063130122	(Get FASTA)	NCBI Sequence Viewer
	XP_063130124	(Get FASTA)	NCBI Sequence Viewer
	XP_063130125	(Get FASTA)	NCBI Sequence Viewer
	XP_063130126	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB88635	(Get FASTA)	NCBI Sequence Viewer
	EDL94133	(Get FASTA)	NCBI Sequence Viewer
	EDL94134	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076873
	ENSRNOP00000092113
	ENSRNOP00000093742
	ENSRNOP00000095354
GenBank Protein	Q62717	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_037351 ⟸ NM_013219

- UniProtKB:

A0A8I5Y0W4 (UniProtKB/TrEMBL), A6K086 (UniProtKB/TrEMBL), F1LLX6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLDPSSSEEESDEILEEESGKEVLGSAASGARLSPSRTNEGSAGSAGMGGSGAGAGVGAGGGGG
SGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQLYVFVMRCIA
YPFNAKQPTDMARRPRKISKQQLQTVKDRFQAFLNGETQIVADEAFMNAVQSYYEVFLKSDRVA
RMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARM
TASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIA
RERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESE
NQLSKSDVLLSFSLEVVIMEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFS
TTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAV
RMDKPQNMKHSGYLWTIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVD
YTDPQPGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLKPRA
ETCLSMDAPISQFYADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSP
GQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGT
VTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEV
KTVIRKCLEQAALVNYSRLSEYAKIEENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEAF
AWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQD
LFAPLVVRYVDLMESSIAQSIHRGFERESWEPVNNGSGTSEDLFWKLDALQTFIRDLHWPEEEF
GKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLC
SMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAA
SKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQ
LHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEERTASVSEGGGLQGISMKD
SDEEDEEDD

hide sequence

Ensembl Acc Id:

ENSRNOP00000012153 ⟸ ENSRNOT00000012153

RefSeq Acc Id:	XP_038948999 ⟸ XM_039093071
- Peptide Label:	isoform X15
- UniProtKB:	F1LLX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948992 ⟸ XM_039093064
- Peptide Label:	isoform X9
- UniProtKB:	F1LLX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948978 ⟸ XM_039093050
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A5K7 (UniProtKB/TrEMBL), A0A8I6ATV6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948995 ⟸ XM_039093067
- Peptide Label:	isoform X11
- UniProtKB:	F1LLX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948983 ⟸ XM_039093055
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6AGZ8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948988 ⟸ XM_039093060
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6AGZ8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095628 ⟸ ENSRNOT00000094787

Ensembl Acc Id:

ENSRNOP00000076873 ⟸ ENSRNOT00000094744

Ensembl Acc Id:

ENSRNOP00000095354 ⟸ ENSRNOT00000099157

Ensembl Acc Id:

ENSRNOP00000092113 ⟸ ENSRNOT00000098925

Ensembl Acc Id:

ENSRNOP00000093742 ⟸ ENSRNOT00000105737

Ensembl Acc Id:

ENSRNOP00000086566 ⟸ ENSRNOT00000115067

RefSeq Acc Id:	XP_063130116 ⟸ XM_063274046
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AGZ8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130119 ⟸ XM_063274049
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AGZ8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130122 ⟸ XM_063274052
- Peptide Label:	isoform X10
- UniProtKB:	F1LLX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130118 ⟸ XM_063274048
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ATV6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130120 ⟸ XM_063274050
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6AGZ8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130124 ⟸ XM_063274054
- Peptide Label:	isoform X12
- UniProtKB:	F1LLX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130121 ⟸ XM_063274051
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6AGZ8 (UniProtKB/TrEMBL), A0A8I6AI45 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130125 ⟸ XM_063274055
- Peptide Label:	isoform X13

RefSeq Acc Id:	XP_063130126 ⟸ XM_063274056
- Peptide Label:	isoform X14

Protein Domains

C2 MHD1 PH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62717-F1-model_v2	AlphaFold	Q62717	1-1289	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708573	AgrOrtholog
BioCyc Gene	G2FUF-14357	BioCyc
Ensembl Genes	ENSRNOG00000008570	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000094744	ENTREZGENE
	ENSRNOT00000098925	ENTREZGENE
	ENSRNOT00000099157	ENTREZGENE
	ENSRNOT00000105737	ENTREZGENE
Gene3D-CATH	1.10.357.50	UniProtKB/Swiss-Prot
	2.30.29.30	UniProtKB/Swiss-Prot
InterPro	C2_dom	UniProtKB/Swiss-Prot
	CAPS	UniProtKB/Swiss-Prot
	CAPS_dom	UniProtKB/Swiss-Prot
	Munc13_1	UniProtKB/Swiss-Prot
	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PH_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:26989	UniProtKB/Swiss-Prot
NCBI Gene	26989	ENTREZGENE
PANTHER	CALCIUM-DEPENDENT SECRETION ACTIVATOR 1	UniProtKB/Swiss-Prot
	PTHR12166	UniProtKB/Swiss-Prot
Pfam	C2_CAPS	UniProtKB/Swiss-Prot
	DUF1041	UniProtKB/Swiss-Prot
	PF00169	UniProtKB/Swiss-Prot
PhenoGen	Cadps	PhenoGen
PROSITE	MHD1	UniProtKB/Swiss-Prot
	PH_DOMAIN	UniProtKB/Swiss-Prot
	PS50004	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008570	RatGTEx
SMART	DUF1041	UniProtKB/Swiss-Prot
	SM00233	UniProtKB/Swiss-Prot
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y0W4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A5K7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AGZ8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AI45	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ATV6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B2G7_RAT	UniProtKB/TrEMBL
	A6K086	ENTREZGENE, UniProtKB/TrEMBL
	A6K087_RAT	UniProtKB/TrEMBL
	CAPS1_RAT	UniProtKB/Swiss-Prot
	F1LLX6	ENTREZGENE
	Q62717	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Cadps	calcium dependent secretion activator	LOC103690082	calcium-dependent secretion activator 1-like	Data merged from RGD:9360488	737654	PROVISIONAL
2016-06-22	Cadps	calcium dependent secretion activator	Cadps	Ca2+ dependent secretion activator	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Cadps	Ca2+ dependent secretion activator	Cadps	Ca++-dependent secretion activator	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103690082	calcium-dependent secretion activator 1-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-09-29	Cadps	Ca++-dependent secretion activator	Cadps	Ca2+-dependent secretion activator	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-06-27			Cadps	Ca2+-dependent secretion activator	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Cadps	Ca2+-dependent secretion activator		Ca<2+-dependent activator protein for secretion	Name updated	1299863	APPROVED
2004-12-14	Cadps	Ca<2+-dependent activator protein for secretion	Caps	Ca2+-dependent activator protein	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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