Sh3gl1 (SH3 domain containing GRB2 like 1, endophilin A2) - Rat Genome Database

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Gene: Sh3gl1 (SH3 domain containing GRB2 like 1, endophilin A2) Rattus norvegicus
Analyze
Symbol: Sh3gl1
Name: SH3 domain containing GRB2 like 1, endophilin A2
RGD ID: 708456
Description: Enables several functions, including SH3 domain binding activity; beta-1 adrenergic receptor binding activity; and enzyme binding activity. Involved in modulation of excitatory postsynaptic potential and positive regulation of synaptic vesicle endocytosis. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density, intracellular component. Used to study high grade glioma. Human ortholog(s) of this gene implicated in acute myeloid leukemia and high grade glioma. Orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: endophilin-2; endophilin-A2; LOC81922; SH3 domain protein 2B; SH3 domain-containing GRB2-like 1; SH3 domain-containing GRB2-like protein 1; SH3-domain GRB2-like 1; SH3P8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89929,459 - 956,922 (-)NCBIGRCr8
mRatBN7.29842,285 - 869,753 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9842,288 - 869,716 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,293,680 - 1,316,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,640,221 - 6,663,407 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,598,716 - 5,621,903 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0911,031,847 - 11,055,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl911,031,841 - 11,055,285 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0910,018,274 - 10,040,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,637,327 - 7,660,492 (+)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Formation of an endophilin-Ca2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis. Chen Y, etal., Cell. 2003 Oct 3;115(1):37-48.
2. Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. Chowdhury S, etal., Neuron. 2006 Nov 9;52(3):445-59.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomas. Matsutani T, etal., J Exp Clin Cancer Res. 2012 Oct 11;31:85. doi: 10.1186/1756-9966-31-85.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals. Nemoto Y, etal., J Biol Chem 2001 Nov 2;276(44):41133-42.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Differential expression of endophilin 1 and 2 dimers at central nervous system synapses. Ringstad N, etal., J Biol Chem. 2001 Nov 2;276(44):40424-30. doi: 10.1074/jbc.M106338200. Epub 2001 Aug 22.
13. The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. Ringstad N, etal., Proc Natl Acad Sci U S A 1997 Aug 5;94(16):8569-74.
14. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
16. Endophilin isoforms have distinct characteristics in interactions with N-type Ca2+ channels and dynamin I. Tian Q, etal., Neurosci Bull. 2012 Oct;28(5):483-92. doi: 10.1007/s12264-012-1257-z. Epub 2012 Jul 13.
17. Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis. Vehlow A, etal., EMBO J. 2013 Oct 16;32(20):2722-34. doi: 10.1038/emboj.2013.212. Epub 2013 Sep 27.
18. Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling. Voglmaier SM, etal., Neuron. 2006 Jul 6;51(1):71-84. doi: 10.1016/j.neuron.2006.05.027.
19. A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains. Wuertenberger S and Groemping Y, FEBS Lett. 2015 Apr 28;589(10):1156-63. doi: 10.1016/j.febslet.2015.03.014. Epub 2015 Mar 24.
20. Characterization of two distinct modes of endophilin in clathrin-mediated endocytosis. Zhang J, etal., Cell Signal. 2012 Nov;24(11):2043-50. doi: 10.1016/j.cellsig.2012.06.006. Epub 2012 Jun 27.
Additional References at PubMed
PMID:15489334   PMID:15659545   PMID:16115810   PMID:16189514   PMID:21900206   PMID:22099461   PMID:25468996   PMID:25517096   PMID:28235806   PMID:28758034   PMID:29574155   PMID:29923351  
PMID:30053369   PMID:33504785  


Genomics

Comparative Map Data
Sh3gl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89929,459 - 956,922 (-)NCBIGRCr8
mRatBN7.29842,285 - 869,753 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9842,288 - 869,716 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,293,680 - 1,316,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,640,221 - 6,663,407 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,598,716 - 5,621,903 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0911,031,847 - 11,055,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl911,031,841 - 11,055,285 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0910,018,274 - 10,040,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,637,327 - 7,660,492 (+)NCBICelera
Cytogenetic Map9q11NCBI
SH3GL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,360,370 - 4,400,547 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,360,370 - 4,400,547 (-)EnsemblGRCh38hg38GRCh38
GRCh37194,360,367 - 4,400,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,311,367 - 4,351,471 (-)NCBINCBI36Build 36hg18NCBI36
Build 34194,311,367 - 4,351,471NCBI
Celera194,298,613 - 4,338,694 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,122,883 - 4,162,918 (-)NCBIHuRef
CHM1_1194,360,010 - 4,400,159 (-)NCBICHM1_1
T2T-CHM13v2.0194,343,819 - 4,383,971 (-)NCBIT2T-CHM13v2.0
Sh3gl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,323,750 - 56,343,659 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,323,750 - 56,343,635 (-)EnsemblGRCm39 Ensembl
GRCm381756,016,750 - 56,036,659 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,016,750 - 56,036,635 (-)EnsemblGRCm38mm10GRCm38
MGSCv371756,156,173 - 56,175,999 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,610,043 - 55,629,869 (-)NCBIMGSCv36mm8
Celera1759,435,412 - 59,455,238 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.11NCBI
Sh3gl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,502,173 - 4,531,758 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,502,173 - 4,531,758 (+)NCBIChiLan1.0ChiLan1.0
SH3GL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,758,290 - 8,798,179 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,987,387 - 8,027,288 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,383,267 - 3,423,165 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,329,750 - 4,336,356 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,329,750 - 4,340,121 (-)Ensemblpanpan1.1panPan2
SH3GL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,279,622 - 55,311,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,279,621 - 55,311,536 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,007,793 - 55,039,737 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,938,684 - 55,970,631 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,938,677 - 55,980,136 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,999,266 - 55,031,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,480,162 - 55,512,107 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,678,880 - 55,710,790 (+)NCBIUU_Cfam_GSD_1.0
Sh3gl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,298,810 - 215,330,409 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,504,374 - 2,536,011 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,504,372 - 2,535,993 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3GL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,414,466 - 74,445,447 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,414,453 - 74,445,450 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2274,907,406 - 74,938,402 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SH3GL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,090,800 - 4,130,566 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl64,091,359 - 4,130,578 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,072,672 - 4,112,482 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3gl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,305,070 - 5,330,440 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,304,887 - 5,330,440 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sh3gl1
47 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:383
Count of miRNA genes:195
Interacting mature miRNAs:225
Transcripts:ENSRNOT00000074695
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat

Markers in Region
RH137013  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29846,570 - 846,720 (-)MAPPERmRatBN7.2
Rnor_6.0911,055,096 - 11,055,245NCBIRnor6.0
Rnor_5.0910,040,385 - 10,040,534UniSTSRnor5.0
Celera97,660,303 - 7,660,452UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000074695   ⟹   ENSRNOP00000066789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9846,578 - 869,691 (-)Ensembl
Rnor_6.0 Ensembl911,031,841 - 11,055,285 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105687   ⟹   ENSRNOP00000094441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9842,288 - 869,716 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107608   ⟹   ENSRNOP00000083818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9846,578 - 855,251 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110808   ⟹   ENSRNOP00000084032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9846,578 - 869,691 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117244   ⟹   ENSRNOP00000078072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9846,578 - 850,438 (-)Ensembl
RefSeq Acc Id: NM_031239   ⟹   NP_112518
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89933,704 - 956,890 (-)NCBI
mRatBN7.29846,530 - 869,716 (-)NCBI
Rnor_6.0911,031,847 - 11,055,285 (+)NCBI
Rnor_5.0910,018,274 - 10,040,574 (+)NCBI
Celera97,637,327 - 7,660,492 (+)RGD
Sequence:
RefSeq Acc Id: XM_039084253   ⟹   XP_038940181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89929,459 - 956,920 (-)NCBI
mRatBN7.29842,285 - 869,750 (-)NCBI
RefSeq Acc Id: XM_039084254   ⟹   XP_038940182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89933,704 - 956,921 (-)NCBI
mRatBN7.29846,530 - 869,752 (-)NCBI
RefSeq Acc Id: XM_063267775   ⟹   XP_063123845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89929,459 - 956,922 (-)NCBI
RefSeq Acc Id: NP_112518   ⟸   NM_031239
- UniProtKB: O35964 (UniProtKB/Swiss-Prot),   A6KR11 (UniProtKB/TrEMBL),   A0A8I5YC58 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066789   ⟸   ENSRNOT00000074695
RefSeq Acc Id: XP_038940181   ⟸   XM_039084253
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YC58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940182   ⟸   XM_039084254
- Peptide Label: isoform X2
- UniProtKB: A0A8I5YC58 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083818   ⟸   ENSRNOT00000107608
Ensembl Acc Id: ENSRNOP00000094441   ⟸   ENSRNOT00000105687
Ensembl Acc Id: ENSRNOP00000084032   ⟸   ENSRNOT00000110808
Ensembl Acc Id: ENSRNOP00000078072   ⟸   ENSRNOT00000117244
RefSeq Acc Id: XP_063123845   ⟸   XM_063267775
- Peptide Label: isoform X3
Protein Domains
BAR   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35964-F1-model_v2 AlphaFold O35964 1-368 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696472
Promoter ID:EPDNEW_R6997
Type:initiation region
Name:Sh3gl1_1
Description:SH3 domain containing GRB2 like 1, endophilin A2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0911,031,802 - 11,031,862EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708456 AgrOrtholog
BIND 130567
  134433
BioCyc Gene G2FUF-28567 BioCyc
Ensembl Genes ENSRNOG00000049683 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055014991 UniProtKB/Swiss-Prot
  ENSRNOG00065013351 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074695.3 UniProtKB/Swiss-Prot
  ENSRNOT00000105687.1 UniProtKB/TrEMBL
  ENSRNOT00000107608.1 UniProtKB/TrEMBL
  ENSRNOT00000110808.1 UniProtKB/Swiss-Prot
  ENSRNOT00000117244.1 UniProtKB/TrEMBL
  ENSRNOT00055025695 UniProtKB/Swiss-Prot
  ENSRNOT00065022026 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7099223 IMAGE-MGC_LOAD
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin_A_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin_SH3RF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81922 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91401 IMAGE-MGC_LOAD
NCBI Gene 81922 ENTREZGENE
PANTHER PTHR14167:SF63 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sh3gl1 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049683 RatGTEx
  ENSRNOG00055014991 RatGTEx
  ENSRNOG00065013351 RatGTEx
SMART BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YC58 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0Q5_RAT UniProtKB/TrEMBL
  A0A8I6AHS1_RAT UniProtKB/TrEMBL
  A6KR11 ENTREZGENE, UniProtKB/TrEMBL
  A6KR13_RAT UniProtKB/TrEMBL
  O35964 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-19 Sh3gl1  SH3 domain containing GRB2 like 1, endophilin A2  Sh3gl1  SH3 domain-containing GRB2-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-04 Sh3gl1  SH3 domain-containing GRB2-like 1  Sh3gl1  SH3-domain GRB2-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Sh3gl1  SH3-domain GRB2-like 1  LOC81922    Symbol updated 1299863 APPROVED