Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Plcl1 | Rat | 1,1-dichloroethene | decreases expression | ISO | Plcl1 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of PLCL1 mRNA | CTD | PMID:26682919 | Plcl1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Plcl1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of PLCL1 mRNA | CTD | PMID:28960355 | Plcl1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of PLCL1 mRNA | CTD | PMID:29097150 | Plcl1 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Estradiol] results in increased expression of PLCL1 mRNA | CTD | PMID:32741896 | Plcl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Plcl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PLCL1 mRNA | CTD | PMID:19933214 | Plcl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PLCL1 mRNA | CTD | PMID:33387578|PMID:34747641 | Plcl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PLCL1 mRNA | CTD | PMID:32109520 | Plcl1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCL1 mRNA | CTD | PMID:23196670 | Plcl1 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | PLCL1 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of PLCL1 gene | CTD | PMID:31601247 | Plcl1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PLCL1 mRNA | CTD | PMID:24780913 | Plcl1 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of PLCL1 mRNA | CTD | PMID:31881176 | Plcl1 | Rat | aflatoxin B1 | affects expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of PLCL1 protein | CTD | PMID:20106945 | Plcl1 | Rat | aflatoxin B1 | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of PLCL1 mRNA | CTD | PMID:22100608 | Plcl1 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PLCL1 mRNA | CTD | PMID:35163327 | Plcl1 | Rat | amphibole asbestos | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Asbestos, Amphibole results in decreased expression of PLCL1 mRNA | CTD | PMID:20831825 | Plcl1 | Rat | Aroclor 1254 | decreases expression | ISO | Plcl1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of PLCL1 mRNA | CTD | PMID:23650126 | Plcl1 | Rat | arsenous acid | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PLCL1 mRNA | CTD | PMID:24356939 | Plcl1 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of PLCL1 gene | CTD | PMID:28931070 | Plcl1 | Rat | benzo[a]pyrene | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PLCL1 mRNA | CTD | PMID:20106945 | Plcl1 | Rat | benzo[a]pyrene | increases methylation | ISO | PLCL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PLCL1 promoter | CTD | PMID:27901495 | Plcl1 | Rat | benzo[a]pyrene | increases methylation | ISO | Plcl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of PLCL1 3' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Plcl1 | Rat | benzo[a]pyrene | increases expression | ISO | Plcl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PLCL1 mRNA | CTD | PMID:27195522 | Plcl1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PLCL1 mRNA | CTD | PMID:25181051 | Plcl1 | Rat | bisphenol A | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PLCL1 mRNA | CTD | PMID:27685785 | Plcl1 | Rat | bisphenol F | increases expression | ISO | Plcl1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of PLCL1 mRNA | CTD | PMID:30951980 | Plcl1 | Rat | bisphenol F | multiple interactions | ISO | PLCL1 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of PLCL1 gene | CTD | PMID:31601247 | Plcl1 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Plcl1 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of PLCL1 intron | CTD | PMID:28392331 | Plcl1 | Rat | carbon nanotube | decreases expression | ISO | Plcl1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of PLCL1 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Plcl1 | Rat | CGP 52608 | multiple interactions | ISO | PLCL1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PLCL1 gene] | CTD | PMID:28238834 | Plcl1 | Rat | clothianidin | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | clothianidin results in decreased expression of PLCL1 mRNA | CTD | PMID:31626844 | Plcl1 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of PLCL1 mRNA | CTD | PMID:24386269 | Plcl1 | Rat | cobalt dichloride | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of PLCL1 mRNA | CTD | PMID:19320972 | Plcl1 | Rat | crocidolite asbestos | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in decreased expression of PLCL1 mRNA | CTD | PMID:20831825 | Plcl1 | Rat | cyclosporin A | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PLCL1 mRNA | CTD | PMID:20106945 | Plcl1 | Rat | diarsenic trioxide | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PLCL1 mRNA | CTD | PMID:24356939 | Plcl1 | Rat | Dibutyl phosphate | affects expression | ISO | PLCL1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of PLCL1 mRNA | CTD | PMID:37042841 | Plcl1 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PLCL1 mRNA | CTD | PMID:21266533 | Plcl1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PLCL1 mRNA | CTD | PMID:29391264 | Plcl1 | Rat | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of PLCL1 mRNA | CTD | PMID:20655511 | Plcl1 | Rat | ethanol | affects expression | ISO | Plcl1 (Mus musculus) | 6480464 | Ethanol affects the expression of PLCL1 mRNA | CTD | PMID:30319688 | Plcl1 | Rat | ethanol | multiple interactions | EXP | | 6480464 | N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid inhibits the reaction [Ethanol results in decreased expression of PLCL1 mRNA] | CTD | PMID:20655511 | Plcl1 | Rat | fluoxetine | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Fluoxetine results in increased expression of PLCL1 mRNA | CTD | PMID:24356939 | Plcl1 | Rat | folic acid | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of PLCL1 mRNA | CTD | PMID:21867686 | Plcl1 | Rat | fulvestrant | multiple interactions | ISO | PLCL1 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of PLCL1 gene | CTD | PMID:31601247 | Plcl1 | Rat | fulvestrant | decreases methylation | ISO | PLCL1 (Homo sapiens) | 6480464 | Fulvestrant results in decreased methylation of PLCL1 gene | CTD | PMID:31601247 | Plcl1 | Rat | gamma-hexachlorocyclohexane | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Hexachlorocyclohexane results in increased expression of PLCL1 mRNA | CTD | PMID:24356939 | Plcl1 | Rat | glyphosate | increases expression | ISO | Plcl1 (Mus musculus) | 6480464 | Glyphosate results in increased expression of PLCL1 mRNA | CTD | PMID:35897073 | Plcl1 | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of PLCL1 mRNA | CTD | PMID:20080153 | Plcl1 | Rat | mifepristone | decreases expression | EXP | | 6480464 | Mifepristone results in decreased expression of PLCL1 mRNA | CTD | PMID:25972201 | Plcl1 | Rat | ozone | multiple interactions | ISO | Plcl1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Plcl1 | Rat | paclitaxel | increases expression | EXP | | 6480464 | Paclitaxel analog results in increased expression of PLCL1 mRNA; Paclitaxel results in increased expression of more ... | CTD | PMID:15585946 | Plcl1 | Rat | paracetamol | affects expression | ISO | Plcl1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PLCL1 mRNA | CTD | PMID:17562736 | Plcl1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PLCL1 mRNA | CTD | PMID:33387578 | Plcl1 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PLCL1 mRNA | CTD | PMID:35163327 | Plcl1 | Rat | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of PLCL1 mRNA | CTD | PMID:20345932 | Plcl1 | Rat | pirinixic acid | decreases expression | ISO | Plcl1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of PLCL1 mRNA | CTD | PMID:23811191 | Plcl1 | Rat | prednisolone | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Prednisolone results in increased expression of PLCL1 mRNA | CTD | PMID:24356939 | Plcl1 | Rat | sirolimus | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Sirolimus results in increased expression of PLCL1 mRNA | CTD | PMID:24356939 | Plcl1 | Rat | sodium arsenite | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PLCL1 mRNA | CTD | PMID:25879800 | Plcl1 | Rat | sulforaphane | decreases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of PLCL1 mRNA | CTD | PMID:31838189 | Plcl1 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Estradiol] results in increased expression of PLCL1 mRNA | CTD | PMID:32741896 | Plcl1 | Rat | thiram | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Thiram results in increased expression of PLCL1 mRNA | CTD | PMID:38568856 | Plcl1 | Rat | titanium dioxide | decreases methylation | ISO | Plcl1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PLCL1 gene | CTD | PMID:35295148 | Plcl1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PLCL1 mRNA | CTD | PMID:33387578 | Plcl1 | Rat | trimellitic anhydride | increases expression | ISO | Plcl1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of PLCL1 mRNA | CTD | PMID:19042947 | Plcl1 | Rat | triptonide | increases expression | ISO | Plcl1 (Mus musculus) | 6480464 | triptonide results in increased expression of PLCL1 mRNA | CTD | PMID:33045310 | Plcl1 | Rat | urethane | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Urethane results in increased expression of PLCL1 mRNA | CTD | PMID:28818685 | Plcl1 | Rat | valproic acid | increases expression | ISO | PLCL1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PLCL1 mRNA | CTD | PMID:23179753 | Plcl1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of PLCL1 mRNA | CTD | PMID:23555832 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















