Plcl1 (phospholipase C like 1 (inactive)) - Rat Genome Database

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Gene: Plcl1 (phospholipase C like 1 (inactive)) Ictidomys tridecemlineatus
Analyze
Symbol: Plcl1
Name: phospholipase C like 1 (inactive)
RGD ID: 12464450
Description: ENCODES a protein that exhibits GABA receptor binding (ortholog); INVOLVED IN gamma-aminobutyric acid signaling pathway (ortholog); regulation of synaptic transmission, GABAergic (ortholog); ASSOCIATED WITH Experimental Liver Neoplasms (ortholog); Neurodevelopmental Disorders (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive phospholipase C-like protein 1; phospholipase C like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303155,380,223 - 155,713,949 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365061,125,806 - 1,457,316 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365061,124,318 - 1,457,842 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Plcl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303155,380,223 - 155,713,949 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365061,125,806 - 1,457,316 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365061,124,318 - 1,457,842 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382197,804,593 - 198,149,863 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2197,804,593 - 198,572,581 (+)EnsemblGRCh38hg38GRCh38
GRCh372198,669,317 - 199,014,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362198,539,545 - 198,721,293 (+)NCBINCBI36Build 36hg18NCBI36
Build 342198,656,805 - 198,838,554NCBI
Celera2192,425,193 - 192,770,374 (+)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2190,521,603 - 190,866,928 (+)NCBIHuRef
CHM1_12198,675,428 - 199,020,595 (+)NCBICHM1_1
T2T-CHM13v2.02198,288,252 - 198,633,649 (+)NCBIT2T-CHM13v2.0
Plcl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39155,442,722 - 55,793,444 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl155,445,080 - 55,793,444 (+)EnsemblGRCm39 Ensembl
GRCm38155,405,946 - 55,754,285 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl155,405,921 - 55,754,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv37155,462,790 - 55,811,129 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36155,653,237 - 56,014,883 (+)NCBIMGSCv36mm8
Celera155,926,260 - 56,273,512 (+)NCBICelera
Cytogenetic Map1C1.2NCBI
cM Map128.15NCBI
Plcl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8964,395,976 - 64,733,171 (+)NCBIGRCr8
mRatBN7.2956,901,573 - 57,238,782 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl956,901,534 - 57,238,782 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx965,406,716 - 65,743,988 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0970,522,633 - 70,859,895 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0968,828,156 - 69,179,166 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0962,016,112 - 62,349,244 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl962,291,405 - 62,349,309 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0961,824,561 - 62,158,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4954,207,542 - 54,546,228 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1954,335,647 - 54,676,737 (+)NCBI
Celera954,380,510 - 54,712,666 (+)NCBICelera
Cytogenetic Map9q31NCBI
Plcl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554032,641,360 - 2,693,352 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554032,643,092 - 2,904,651 (-)NCBIChiLan1.0ChiLan1.0
PLCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213100,423,115 - 100,771,724 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B100,438,108 - 100,786,717 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B85,054,907 - 85,397,171 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B202,947,931 - 203,286,656 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B202,947,927 - 203,286,649 (+)Ensemblpanpan1.1panPan2
PLCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1377,235,403 - 7,575,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl377,235,424 - 7,562,708 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha378,181,566 - 8,509,686 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0377,125,882 - 7,454,891 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl377,125,882 - 7,455,347 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1377,124,391 - 7,452,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0377,090,950 - 7,418,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0377,115,313 - 7,444,018 (+)NCBIUU_Cfam_GSD_1.0
PLCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15101,840,806 - 101,951,106 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115101,602,336 - 102,424,225 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215112,689,632 - 113,486,939 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11083,291,683 - 83,640,634 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1083,574,894 - 83,642,768 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040115,809,308 - 116,157,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248892,271,043 - 2,559,396 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248892,225,082 - 2,559,379 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005324334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000027363   ⟹   ENSSTOP00000019801
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365061,125,806 - 1,457,316 (-)Ensembl
RefSeq Acc Id: XM_005324334   ⟹   XP_005324391
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303155,380,223 - 155,713,949 (+)NCBI
SpeTri2.0NW_0049365061,124,318 - 1,457,842 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005324391 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019801.2
GenBank Protein KAG3274928 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005324391   ⟸   XM_005324334
- UniProtKB: I3N605 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000019801   ⟸   ENSSTOT00000027363
Protein Domains
C2   PH   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026164 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000027363.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
NCBI Gene Plcl1 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF102 UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt I3N605 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-16 Plcl1  phospholipase C like 1 (inactive)    phospholipase C like 1  Symbol and/or name change 5135510 APPROVED