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Gene: Rbck1 (RANBP2-type and C3HC4-type zinc finger containing 1) Rattus norvegicus

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Symbol:

Rbck1

Name:

RANBP2-type and C3HC4-type zinc finger containing 1

RGD ID:

708404

Description:

Enables double-stranded DNA binding activity and protein kinase C binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of LUBAC complex. Human ortholog(s) of this gene implicated in glycogen storage disease. Orthologous to human RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; allethrin.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

heme-oxidized IRP2 ubiquitin ligase 1 homolog; HOIL-1; LOC60383; Pkcbpb15; protein kinase C-binding protein beta-15; protein kinase C-binding protein Beta15; RanBP-type and C3HC4-type zinc finger containing 1; ranBP-type and C3HC4-type zinc finger-containing protein 1; RBCC protein interacting with PKC 1; RING-type E3 ubiquitin transferase HOIL-1; ubiquitin-conjugating enzyme 7-interacting protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	161,249,389 - 161,266,321 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	161,249,390 - 161,266,032 (-)	Ensembl				GRCr8
mRatBN7.2	3	140,789,079 - 140,806,017 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	140,789,080 - 140,806,005 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	144,693,960 - 144,710,813 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	153,277,793 - 153,294,653 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	151,018,228 - 151,034,882 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	147,793,014 - 147,809,941 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	147,793,017 - 147,809,919 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	154,141,154 - 154,158,071 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	142,644,156 - 142,660,799 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	139,541,427 - 139,557,526 (-)	NCBI		Celera
RGSC_v3.1	3	142,549,729 - 142,566,372 (-)	NCBI
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiomegaly (ISO)

genetic disease (ISO)

glycogen storage disease IV (ISO)

Polyglucosan Body Myopathy 1 with or without Immunodeficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

3,4-dichloroaniline (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Bufotalin (ISO)

butan-1-ol (ISO)

Butylbenzyl phthalate (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

dexamethasone (ISO)

diazinon (EXP)

dibutyl phthalate (EXP)

disodium selenite (ISO)

diuron (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

fenvalerate (EXP)

gentamycin (EXP)

hydroquinone (ISO)

hypochlorous acid (ISO)

indometacin (ISO)

isobutanol (ISO)

methidathion (ISO)

methoxychlor (EXP)

N-methyl-N-nitrosourea (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

nicotine (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

phenylephrine (EXP)

pyrethrins (EXP)

quercetin (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to bacterium (IEA,ISO,ISS)

negative regulation of necroptotic process (ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of canonical NF-kappaB signal transduction (IBA,IEA,ISO,ISS)

positive regulation of extrinsic apoptotic signaling pathway (ISO)

positive regulation of macromolecule metabolic process (IEA)

positive regulation of metabolic process (IEA)

positive regulation of non-canonical NF-kappaB signal transduction (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IDA)

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA,IEA,ISO)

protein linear polyubiquitination (IBA,IEA,ISO,ISS)

protein polyubiquitination (IEA,ISO)

protein ubiquitination (IEA)

regulation of primary metabolic process (IEA)

T cell receptor signaling pathway (IEA,ISO)

Cellular Component

LUBAC complex (IBA,IEA,ISO,ISS)

Molecular Function

double-stranded DNA binding (IDA)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

protein binding (IPI,ISO)

protein kinase C binding (IPI)

protein sequestering activity (ISO)

transcription coactivator activity (ISO)

transferase activity (IEA)

ubiquitin binding (IBA,IEA,ISO,ISS)

ubiquitin ligase activator activity (IEA,ISO)

ubiquitin protein ligase activity (IEA)

ubiquitin-protein transferase activity (IBA,IEA,ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

nuclear factor kappa B signaling pathway (ISO)

tumor necrosis factor mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Tumor necrosis factor.	Chu WM, Cancer Lett. 2013 Jan 28;328(2):222-5. doi: 10.1016/j.canlet.2012.10.014. Epub 2012 Oct 22.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
6.	Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins.	Tokunaga C, etal., Biochem Biophys Res Commun 1998 Mar 17;244(2):353-9.
7.	Molecular cloning and characterization of RBCK2, a splicing variant of a RBCC family protein, RBCK1.	Tokunaga C, etal., FEBS Lett 1998 Sep 11;435(1):11-5.
8.	Accumulation of polyubiquitinated proteins by overexpression of RBCC protein interacting with protein kinase C2, a splice variant of ubiquitin ligase RBCC protein interacting with protein kinase C1.	Yoshimoto N, etal., FEBS J. 2009 Nov;276(21):6375-85. doi: 10.1111/j.1742-4658.2009.07350.x. Epub 2009 Oct 1.

Additional References at PubMed

PMID:12629548	PMID:15833741	PMID:17006537	PMID:17121852	PMID:17449468	PMID:19028597	PMID:19136968	PMID:20005846	PMID:21455173	PMID:21455180	PMID:21455181	PMID:22089168
PMID:23453807	PMID:24726323	PMID:25416956	PMID:27523608	PMID:30561431

Genomics

Comparative Map Data

Rbck1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	161,249,389 - 161,266,321 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	161,249,390 - 161,266,032 (-)	Ensembl				GRCr8
mRatBN7.2	3	140,789,079 - 140,806,017 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	140,789,080 - 140,806,005 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	144,693,960 - 144,710,813 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	153,277,793 - 153,294,653 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	151,018,228 - 151,034,882 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	147,793,014 - 147,809,941 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	147,793,017 - 147,809,919 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	154,141,154 - 154,158,071 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	142,644,156 - 142,660,799 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	139,541,427 - 139,557,526 (-)	NCBI		Celera
RGSC_v3.1	3	142,549,729 - 142,566,372 (-)	NCBI
Cytogenetic Map	3	q41	NCBI

RBCK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	408,299 - 432,139 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	407,498 - 432,139 (+)	Ensembl			hg38	GRCh38
GRCh37	20	388,943 - 412,783 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	336,709 - 359,610 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	336,755 - 359,610	NCBI
Celera	20	483,557 - 506,462 (+)	NCBI		Celera
Cytogenetic Map	20	p13	NCBI
HuRef	20	340,142 - 362,963 (+)	NCBI		HuRef
CHM1_1	20	388,711 - 411,612 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	451,838 - 475,908 (+)	NCBI		T2T-CHM13v2.0

Rbck1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	152,158,254 - 152,174,592 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	152,158,254 - 152,174,573 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	152,316,334 - 152,332,663 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	152,316,334 - 152,332,653 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	152,142,070 - 152,158,375 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	152,007,778 - 152,024,076 (-)	NCBI		MGSCv36	mm8
Celera	2	158,130,477 - 158,146,782 (-)	NCBI		Celera
Cytogenetic Map	2	G3	NCBI
cM Map	2	74.83	NCBI

Rbck1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955597	271,897 - 289,348 (+)	Ensembl
ChiLan1.0	NW_004955597	272,352 - 289,348 (+)	NCBI	ChiLan1.0	ChiLan1.0

RBCK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	1,496,107 - 1,519,662 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	1,493,162 - 1,516,494 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	615,987 - 639,366 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	386,569 - 409,587 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	386,569 - 409,580 (+)	Ensembl			panPan2	panpan1.1

RBCK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	20,423,378 - 20,440,985 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	20,423,988 - 20,441,114 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	20,077,323 - 20,094,821 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	21,116,652 - 21,134,123 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	21,116,180 - 21,134,273 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	20,391,937 - 20,409,382 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	20,497,899 - 20,515,382 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	20,928,435 - 20,945,897 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rbck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	169,626,204 - 169,641,220 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	18,057,534 - 18,071,816 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	18,057,569 - 18,071,787 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RBCK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	34,784,016 - 34,801,230 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	34,784,018 - 34,801,228 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	39,566,871 - 39,579,566 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RBCK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	35,537,387 - 35,559,628 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	35,538,127 - 35,560,129 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
ChlSab1.1 Ensembl	2	35,538,127 - 35,560,129 (+)	NCBI		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666571	11,131 - 28,078 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rbck1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	1,502,942 - 1,523,675 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	1,503,017 - 1,523,542 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rbck1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	131,641,110 - 131,657,817 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rbck1
263 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	332
Count of miRNA genes:	198
Interacting mature miRNAs:	240
Transcripts:	ENSRNOT00000045314
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	141508991	166376254	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	141508991	177728348	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	160357340	167835660	Rat

Markers in Region

BE109253

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	140,802,339 - 140,802,509 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	147,806,273 - 147,806,442	NCBI	Rnor6.0
Rnor_5.0	3	154,154,414 - 154,154,583	UniSTS	Rnor5.0
RGSC_v3.4	3	142,657,415 - 142,657,584	UniSTS	RGSC3.4
RH 3.4 Map	3	1271.3	UniSTS
Cytogenetic Map	3	q41	UniSTS

AU048771

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	140,797,885 - 140,798,142 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	147,801,822 - 147,802,076	NCBI	Rnor6.0
Rnor_5.0	3	154,149,963 - 154,150,217	UniSTS	Rnor5.0
RGSC_v3.4	3	142,652,963 - 142,653,217	UniSTS	RGSC3.4
Celera	3	139,550,233 - 139,550,487	UniSTS
Cytogenetic Map	3	q41	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB007133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB011369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U48248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000045314 ⟹ ENSRNOP00000047637

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	161,255,083 - 161,266,032 (-)	Ensembl
mRatBN7.2 Ensembl	3	140,789,081 - 140,805,726 (-)	Ensembl
Rnor_6.0 Ensembl	3	147,793,017 - 147,809,658 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085849 ⟹ ENSRNOP00000075043

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	140,789,080 - 140,806,005 (-)	Ensembl
Rnor_6.0 Ensembl	3	147,793,329 - 147,809,919 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085995 ⟹ ENSRNOP00000072645

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	161,249,390 - 161,266,032 (-)	Ensembl
mRatBN7.2 Ensembl	3	140,789,080 - 140,805,722 (-)	Ensembl
Rnor_6.0 Ensembl	3	147,793,017 - 147,809,658 (-)	Ensembl

RefSeq Acc Id:

NM_021764 ⟹ NP_068532

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	161,249,389 - 161,266,032 (-)	NCBI
mRatBN7.2	3	140,789,080 - 140,805,726 (-)	NCBI
Rnor_6.0	3	147,793,016 - 147,809,658 (-)	NCBI
Rnor_5.0	3	154,141,154 - 154,158,071 (-)	NCBI
RGSC_v3.4	3	142,644,156 - 142,660,799 (-)	RGD
Celera	3	139,541,427 - 139,557,526 (-)	RGD

Sequence:

show sequence

CGCCCGCCCGCCTCCCTCCGTCTCTTGCTTTTGGGTCGTGGTTACCCATCGCCCTTTGCGGCCT
TGGCCCTGTGTCTCCTTCGCTTTCTGTGTTCCTCGCAGGGCCCTACTGGGTCCCAATGCCAGAC
TTTGGCCCTTCGGCAGTGTGATGCTGCCCGAGTGTAGACCGGGACACACGCACAAGGCCGACTA
GGACTGAGTTGCTTCTGCCCTCCCTCCCTCTCCCAGGTTACCCCAAGGTAGCGTTTCCCGGAAG
CAGCAGCCCTTTCTGAGGGGATGGGCGCAGCCAGGCCAGATGGACGAGAAGACCAAGAAAGCAG
AGGAGATGGCCCTGAGCCTTGCCCGGGCAGTGACTGGCGGAGATGAACAGGCTGCAATCAAGTA
TGCCACCTGGCTGGCAGAGCAGAAGGTACCCCTCAGGGTGCAAGTAAAACCCGAGGTTTCCCCA
ACACAAGACATCAGGCTTTGTGTGAGTGTGGAAGATGCTTACATGCACACTGTCACCATTTGGC
TCACAGTACGCCCTGATATGACAGTGGCCTCCCTTAAGGACATGGTATTCCTGGACTATGGCTT
TCCACCCAGCCTGCAGCAGTGGGTGGTTGGACAGAGGCTGGCACGAGACCAGGAGACCTTGCAT
TCACATGGCATTCGACGGAATGGAGACAGTGCTTATCTCTACCTGCTGTCAGCCCGCAACACAT
CACTCAACCCTCAAGAGCTGCAGCGGCAGCGGCAGCTGCGCATGTTGGAAGATTTGGGCTTCAA
GGACCTCACCCTGCAGCCACGGGGTCCCTTGGAACCTGTCCTTCCCAAGCCCAGGACCCACCAG
GAGACGGGGCAGCCAGATGCAGCCCCAGAGTCACCACCGGTGGGCTGGCAGTGCCCTGGCTGCA
CGTTCATCAACAAACCCACACGGCCTGGGTGTGAGATGTGCTGCCGTGCAAGGCCTGAGGCCTA
CCAGATCCCTGCCTCGTACCAGCCTGATGAGGAGGAGCGAGCACGCCTGGCTGGTGAGGAGGAG
GCGCTGCGCCAGTATGAGCAGCGGAAACAGCAGCAGCAGGAGGGGAACTACCTGCAGCACGTGC
AGCTGGAGCAGAGGAGCCTGGTGCTGAACACCGAACCTGCTGAGTGCCCTGTGTGCTACTCAGT
GCTGGCACCCGGTGAGGCCGTGGTGCTGCGTGAGTGTCTGCACACCTTCTGCAGGGAGTGCCTG
CAGGGTACCATCCGAAACAGCCAGGAGGCGGAGGTATCCTGCCCCTTCATTGACAACACCTACT
CATGCCCTGGCAAGCTGCTGGAGAGGGAGATCCGGGCGCTCCTGTCCCCTGAGGACTACCAGCG
TTTCCTGGACCTGGGTGTGTCCATCGCAGAGAATCGAAGCACCTTGAGCTACCACTGCAAGACC
CCCGACTGCAGGGGCTGGTGCTTCTTTGAGGATGACGTCAACGAGTTCACCTGTCCTGTGTGCA
CCCGCGTCAACTGTCTGCTCTGCAAGGCCATCCACGAGCGCATGAATTGCAGAGAGTACCAGGA
TGACCTGGCCCATCGGGCTCGGAATGATGTGGCTGCCCAGCAGACAACTGAGATGCTGAGGGTG
ATGCTGCAGCAAGGCGAGGCCATGTACTGCCCACAGTGCCGGATTGTGGTGCAGAAGAAGGATG
GCTGTGACTGGATCCGCTGTACTGTCTGCCACACTGAGATCTGCTGGGTCACCAAGGGTCCACG
CTGGGGCCCTGGGGGCCCAGGGGACACCAGTGGTGGCTGCCGCTGCCGGGTCAATGGGATTCCA
TGCCATCCAAGCTGTCAAAACTGCCACTAAGTCAAAGATGGTGGCTCTCAGACTGACCCAGCCG
CACATGTATAGCAGTGAACATCAGGGCCAGGCCAAGGGCTTTAGCTCTGGTTTGGCCACAATAC
CTTCAAGCTTGGTAAGGGAGAAAGACTGAGCTGTACTGCAGTCTGATTGCTGTGTTACAAGAAC
CCAGCTGAGCTGATGTCAGCCGCACTGCCTCTGTTGCTTCAAGGGCTTGCTGACCAGACCTCAT
GGCCCTGAGCTAGCTTCCCTACCCTTACTAGCCACCAGCCTTAAACACAGCCTTGGCCTAAGGC
CTGGCGGCTAGTGCTCTGAGCCTCCTGGTGACTCTATTTCCCCTCAGCTTGCTCCCTGAGGACC
CACAGCCGCATCTGTTGCCTTGCTGGCTTTCTGGGTACTTTTTAAAGCTGATGTGAATCCATCC
AGGGCCCAGGTAGACTGGTAGGTCAGGAAACAGCCCATGGGGTCCAGCTCTGCATCCCCCTCTC
TAAGTGAATTAAAGTGTTTTTCCAGGAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235252 ⟹ XP_006235314

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	161,249,389 - 161,266,321 (-)	NCBI
mRatBN7.2	3	140,789,080 - 140,806,017 (-)	NCBI
Rnor_6.0	3	147,793,014 - 147,809,941 (-)	NCBI
Rnor_5.0	3	154,141,154 - 154,158,071 (-)	NCBI

Sequence:

show sequence

CGCCCTCTCAGAGCTTGGCGTTGCCTGGAATTAGTGGTCGGCCAAGGGGCACCTAAACCAAGTG
TCTCTGGTCCGCCAGACCATGTGGTGGAGCGTGCGTGCCAGGAACAGTCTAGTGGTCTGCTCCA
GCGGGTGACCCTGCTCTGTCTCGGGTTACCCCAAGGTAGCGTTTCCCGGAAGCAGCAGCCCTTT
CTGAGGGGATGGGCGCAGCCAGGCCAGATGGACGAGAAGACCAAGAAAGCAGAGGAGATGGCCC
TGAGCCTTGCCCGGGCAGTGGCTGGCGGAGATGAACAGGCTGCAATCAAGTATGCCACCTGGCT
GGCAGAGCAGAAGGTACCCCTCAGGGTGCAAGTAAAACCCGAGGTTTCCCCAACACAAGACATC
AGGCTTTGTGTGAGTGTGGAAGATGCTTACATGCACACTGTCACCATTTGGCTCACAGTACGCC
CTGATATGACAGTGGCCTCCCTTAAGGACATGGTATTCCTGGACTATGGCTTTCCACCCAGCCT
GCAGCAGTGGGTGGTTGGACAGAGGCTGGCACGAGACCAGGAGACCTTGCATTCACATGGCATT
CGACGGAATGGAGACAGTGCTTATCTCTACCTGCTGTCAGCCCGCAACACATCACTCAACCCTC
AAGAGCTGCAGCGGCAGCGGCAGCTGCGCATGTTGGAAGATTTGGGCTTCAAGGACCTCACCCT
GCAGCCACGGGGTCCCTTGGAACCTGTCCTTCCCAAGCCCAGGACCCACCAGGAGACGGGGCAG
CCAGATGCAGCCCCAGAGTCACCACCGGTGGGCTGGCAGTGCCCTGGCTGCACGTTCATCAACA
AACCCACACGGCCTGGGTGTGAGATGTGCTGCCGTGCAAGGCCTGAGGCCTACCAGATCCCTGC
CTCGTACCAGCCTGATGAGGAGGAGCGAGCACGCCTGGCTGGTGAGGAGGAGGCGCTGCGCCAG
TATGAGCAGCGGAAACAGCAGCAGCAGGAGGGGAACTACCTGCAGCACGTGCAGCTGGAGCAGA
GGAGCCTGGTGCTGAACACCGAACCTGCTGAGTGCCCTGTGTGCTACTCAGTGCTGGCACCCGG
TGAGGCCGTGGTGCTGCGTGAGTGTCTGCACACCTTCTGCAGGGAGTGCCTGCAGGGTACCATC
CGAAACAGCCAGGAGGCGGAGGTATCCTGCCCCTTCATTGACAACACCTACTCATGCCCTGGCA
AGCTGCTGGAGAGGGAGATCCGGGCGCTCCTGTCCCCTGAGGACTACCAGCGTTTCCTGGACCT
GGGTGTGTCCATCGCAGAGAATCGAAGCACCTTGAGCTACCACTGCAAGACCCCCGACTGCAGG
GGCTGGTGCTTCTTTGAGGATGACGTCAACGAGTTCACCTGTCCTGTGTGCACCCGCGTCAACT
GTCTGCTCTGCAAGGCCATCCACGAGCGCATGAATTGCAGAGAGTACCAGGATGACCTGGCCCA
TCGGGCTCGGAATGATGTGGCTGCCCAGCAGACAACTGAGATGCTGAGGGTGATGCTGCAGCAA
GGCGAGGCCATGTACTGCCCACAGTGCCGGATTGTGGTGCAGAAGAAGGATGGCTGTGACTGGA
TCCGCTGTACTGTCTGCCACACTGAGATCTGCTGGGTCACCAAGGGTCCACGCTGGGGCCCTGG
GGGCCCAGGGGACACCAGTGGTGGCTGCCGCTGCCGGGTCAATGGGATTCCATGCCATCCAAGC
TGTCAAAACTGCCACTAAGTCAAAGATGGTGGCTCTCAGACTGACCCAGCCGCACATGTATAGC
AGTGAACATCAGGGCCAGGCCAAGGGCTTTAGCTCTGGTTTGGCCACAATACCTTCAAGCTTGG
TAAGGGAGAAAGACTGAGCTGTACTGCAGTCTGATTGCTGTGTTACAAGAACCCAGCTGAGCTG
ATGTCAGCCGCACTGCCTCTGTTGCTTCAAGGGCTTGCTGACCAGACCTCATGGCCCTGAGCTA
GCTTCCCTACCCTTACTAGCCACCAGCCTTAAACACAGCCTTGGCCTAAGGCCTGGCGGCTAGT
GCTCTGAGCCTCCTGGTGACTCTATTTCCCCTCAGCTTGCTCCCTGAGGACCCACAGCCGCATC
TGTTGCCTTGCTGGCTTTCTGGGTACTTTTTAAAGCTGATGTGAATCCATCCAGGGCCCAGGTA
GACTGGTAGGTCAGGAAACAGCCCATGGGGTCCAGCTCTGCATCCCCCTCTCTAAGTGAATTAA
AGTGTTTTTCCAGGAGG

hide sequence

RefSeq Acc Id:

XM_039105766 ⟹ XP_038961694

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	161,256,262 - 161,266,112 (-)	NCBI
mRatBN7.2	3	140,796,076 - 140,805,781 (-)	NCBI

RefSeq Acc Id:

XM_063284455 ⟹ XP_063140525

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	161,249,389 - 161,266,319 (-)	NCBI

RefSeq Acc Id:

XM_063284456 ⟹ XP_063140526

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	161,249,389 - 161,259,307 (-)	NCBI

RefSeq Acc Id:

XM_063284457 ⟹ XP_063140527

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	161,252,283 - 161,266,112 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_068532	(Get FASTA)	NCBI Sequence Viewer
	XP_006235314	(Get FASTA)	NCBI Sequence Viewer
	XP_038961694	(Get FASTA)	NCBI Sequence Viewer
	XP_063140525	(Get FASTA)	NCBI Sequence Viewer
	XP_063140526	(Get FASTA)	NCBI Sequence Viewer
	XP_063140527	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC72243	(Get FASTA)	NCBI Sequence Viewer
	AAH61723	(Get FASTA)	NCBI Sequence Viewer
	BAA33953	(Get FASTA)	NCBI Sequence Viewer
	BAA33954	(Get FASTA)	NCBI Sequence Viewer
	BAA33957	(Get FASTA)	NCBI Sequence Viewer
	EDL86076	(Get FASTA)	NCBI Sequence Viewer
	EDL86077	(Get FASTA)	NCBI Sequence Viewer
	EDL86078	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000047637
	ENSRNOP00000072645
GenBank Protein	Q62921	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_068532 ⟸ NM_021764

- UniProtKB:

Q9QWN4 (UniProtKB/Swiss-Prot), Q9Z334 (UniProtKB/Swiss-Prot), Q62921 (UniProtKB/Swiss-Prot), A0A0G2K3H9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDEKTKKAEEMALSLARAVTGGDEQAAIKYATWLAEQKVPLRVQVKPEVSPTQDIRLCVSVEDA
YMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPSLQQWVVGQRLARDQETLHSHGIRRNGDSAYL
YLLSARNTSLNPQELQRQRQLRMLEDLGFKDLTLQPRGPLEPVLPKPRTHQETGQPDAAPESPP
VGWQCPGCTFINKPTRPGCEMCCRARPEAYQIPASYQPDEEERARLAGEEEALRQYEQRKQQQQ
EGNYLQHVQLEQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVS
CPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDV
NEFTCPVCTRVNCLLCKAIHERMNCREYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQC
RIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH

hide sequence

RefSeq Acc Id:	XP_006235314 ⟸ XM_006235252
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K9L6 (UniProtKB/TrEMBL), A6KHM8 (UniProtKB/TrEMBL), A0A0G2K3H9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDEKTKKAEEMALSLARAVAGGDEQAAIKYATWLAEQKVPLRVQVKPEVSPTQDIRLCVSVEDA YMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPSLQQWVVGQRLARDQETLHSHGIRRNGDSAYL YLLSARNTSLNPQELQRQRQLRMLEDLGFKDLTLQPRGPLEPVLPKPRTHQETGQPDAAPESPP VGWQCPGCTFINKPTRPGCEMCCRARPEAYQIPASYQPDEEERARLAGEEEALRQYEQRKQQQQ EGNYLQHVQLEQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVS CPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDV NEFTCPVCTRVNCLLCKAIHERMNCREYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQC RIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH hide sequence

Ensembl Acc Id:

ENSRNOP00000047637 ⟸ ENSRNOT00000045314

Ensembl Acc Id:

ENSRNOP00000072645 ⟸ ENSRNOT00000085995

Ensembl Acc Id:

ENSRNOP00000075043 ⟸ ENSRNOT00000085849

RefSeq Acc Id:	XP_038961694 ⟸ XM_039105766
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063140525 ⟸ XM_063284455
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K3H9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140526 ⟸ XM_063284456
- Peptide Label:	isoform X3
- UniProtKB:	A6KHM9 (UniProtKB/TrEMBL), D4A367 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140527 ⟸ XM_063284457
- Peptide Label:	isoform X4

Protein Domains

RanBP2-type RING-type Ubiquitin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62921-F1-model_v2	AlphaFold	Q62921	1-508	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692537

Promoter ID:

EPDNEW_R3058

Type:

initiation region

Name:

Rbck1_1

Description:

RANBP2-type and C3HC4-type zinc finger containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R3059

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	147,809,587 - 147,809,647	EPDNEW

RGD ID:

13692542

Promoter ID:

EPDNEW_R3059

Type:

initiation region

Name:

Rbck1_2

Description:

RANBP2-type and C3HC4-type zinc finger containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R3058

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	147,809,909 - 147,809,969	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708404	AgrOrtholog
BioCyc Gene	G2FUF-47275	BioCyc
Ensembl Genes	ENSRNOG00000006695	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000045314	ENTREZGENE
	ENSRNOT00000085995	ENTREZGENE
Gene3D-CATH	1.20.120.1750	UniProtKB/Swiss-Prot
	3.30.40.10	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/Swiss-Prot
	Zn-finger domain of Sec23/24	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:5598480	IMAGE-MGC_LOAD
InterPro	BRcat_RBR_HOIL1	UniProtKB/Swiss-Prot
	HOIL1_RBR_mRING-HC-C3HC3D	UniProtKB/Swiss-Prot
	LUBAC_E3_Ligases	UniProtKB/Swiss-Prot
	Rcat_RBR_HOIL1	UniProtKB/Swiss-Prot
	TRIAD_supradom	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
	Ubiquitin_dom	UniProtKB/Swiss-Prot
	Znf-RING_LisH	UniProtKB/Swiss-Prot
	Znf_RanBP2	UniProtKB/Swiss-Prot
	Znf_RanBP2_sf	UniProtKB/Swiss-Prot
	Znf_RING	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot
	Znf_RING_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:60383	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72463	IMAGE-MGC_LOAD
NCBI Gene	60383	ENTREZGENE
PANTHER	PTHR22770:SF35	UniProtKB/Swiss-Prot
	UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED	UniProtKB/Swiss-Prot
Pfam	LTM	UniProtKB/Swiss-Prot
	zf-RING_UBOX	UniProtKB/Swiss-Prot
PhenoGen	Rbck1	PhenoGen
PROSITE	TRIAD	UniProtKB/Swiss-Prot
	UBIQUITIN_2	UniProtKB/Swiss-Prot
	ZF_RANBP2_1	UniProtKB/Swiss-Prot
	ZF_RANBP2_2	UniProtKB/Swiss-Prot
	ZF_RING_1	UniProtKB/Swiss-Prot
	ZF_RING_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000006695	RatGTEx
SMART	RING	UniProtKB/Swiss-Prot
	ZnF_RBZ	UniProtKB/Swiss-Prot
Superfamily-SCOP	RING/U-box	UniProtKB/Swiss-Prot
	SSF54236	UniProtKB/Swiss-Prot
	SSF90209	UniProtKB/Swiss-Prot
UniProt	A0A0G2K3H9	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2K9L6	ENTREZGENE
	A6KHM8	ENTREZGENE, UniProtKB/TrEMBL
	A6KHM9	ENTREZGENE, UniProtKB/TrEMBL
	D4A367	ENTREZGENE, UniProtKB/TrEMBL
	HOIL1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6P7C9_RAT	UniProtKB/TrEMBL
	Q9QWN4	ENTREZGENE
	Q9Z334	ENTREZGENE
UniProt Secondary	Q9QWN4	UniProtKB/Swiss-Prot
	Q9Z334	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Rbck1	RANBP2-type and C3HC4-type zinc finger containing 1	Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	Pkcbpb15	protein kinase C-binding protein Beta15	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-12-14	Pkcbpb15	protein kinase C-binding protein Beta15	LOC60383		Symbol updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations