Psip1 (PC4 and SRSF1 interacting protein 1) - Rat Genome Database

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Gene: Psip1 (PC4 and SRSF1 interacting protein 1) Rattus norvegicus
Analyze
Symbol: Psip1
Name: PC4 and SRSF1 interacting protein 1
RGD ID: 631439
Description: Enables supercoiled DNA binding activity. Predicted to be involved in several processes, including mRNA 5'-splice site recognition; positive regulation of transcription by RNA polymerase II; and response to heat. Located in euchromatin and heterochromatin. Orthologous to human PSIP1 (PC4 and SRSF1 interacting protein 1); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ledgf; lens epithelium-derived growth factor; PC4 and SFRS1 interacting protein 1; PC4 and SFRS1 interacting protein 2; PC4 and SFRS1-interacting protein; Psip2; SBP75; supercoiled DNA binding protein 75
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85102,892,929 - 102,925,191 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5102,892,932 - 102,925,170 (-)EnsemblGRCr8
mRatBN7.2597,847,010 - 97,879,280 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl597,847,015 - 97,879,257 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5100,239,507 - 100,270,774 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05102,032,078 - 102,063,318 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05102,050,380 - 102,081,647 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05101,555,691 - 101,588,659 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5101,555,694 - 101,588,598 (-)Ensemblrn6Rnor6.0
Rnor_5.05105,568,304 - 105,601,260 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45102,304,948 - 102,336,608 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera596,399,960 - 96,431,195 (-)NCBICelera
RGSC_v3.15102,310,173 - 102,341,834 (-)NCBI
Cytogenetic Map5q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
deoxynivalenol  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydroxyurea  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
levetiracetam  (EXP)
lithium atom  (ISO)
lithium hydride  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
miconazole  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-anisidine  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
senecionine  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (EXP)
Tributyltin oxide  (ISO)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
euchromatin  (IDA)
heterochromatin  (IDA,ISO,ISS)
nuclear periphery  (ISO,ISS)
nucleolus  (IDA,ISO)
nucleoplasm  (IEA,ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells. Kubo E, etal., Histochem Cell Biol 2003 Apr;119(4):289-99.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain. Tsutsui KM, etal., Nucleic Acids Res. 2011 Jul;39(12):5067-81. doi: 10.1093/nar/gkr088. Epub 2011 Feb 23.
Additional References at PubMed
PMID:3366776   PMID:9822615   PMID:9885563   PMID:11027629   PMID:11512661   PMID:12477932   PMID:12796494   PMID:18652779   PMID:20974633   PMID:22658674   PMID:22681889   PMID:26721387  


Genomics

Comparative Map Data
Psip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85102,892,929 - 102,925,191 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5102,892,932 - 102,925,170 (-)EnsemblGRCr8
mRatBN7.2597,847,010 - 97,879,280 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl597,847,015 - 97,879,257 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5100,239,507 - 100,270,774 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05102,032,078 - 102,063,318 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05102,050,380 - 102,081,647 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05101,555,691 - 101,588,659 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5101,555,694 - 101,588,598 (-)Ensemblrn6Rnor6.0
Rnor_5.05105,568,304 - 105,601,260 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45102,304,948 - 102,336,608 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera596,399,960 - 96,431,195 (-)NCBICelera
RGSC_v3.15102,310,173 - 102,341,834 (-)NCBI
Cytogenetic Map5q31NCBI
PSIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38915,464,066 - 15,510,970 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl915,464,065 - 15,511,202 (-)Ensemblhg38GRCh38
GRCh37915,464,064 - 15,510,968 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36915,454,064 - 15,500,982 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34915,454,065 - 15,500,982NCBI
Celera915,397,404 - 15,444,340 (-)NCBICelera
Cytogenetic Map9p22.3NCBI
HuRef915,427,681 - 15,474,611 (-)NCBIHuRef
CHM1_1915,464,652 - 15,511,590 (-)NCBICHM1_1
T2T-CHM13v2.0915,475,998 - 15,522,882 (-)NCBIT2T-CHM13v2.0
Psip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39483,373,917 - 83,404,700 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl483,373,917 - 83,404,696 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38483,455,680 - 83,486,463 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl483,455,680 - 83,486,459 (-)Ensemblmm10GRCm38
MGSCv37483,101,584 - 83,132,294 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36482,926,911 - 82,957,621 (-)NCBIMGSCv36mm8
Celera481,990,132 - 82,020,322 (-)NCBICelera
Cytogenetic Map4C3NCBI
cM Map439.46NCBI
Psip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543418,312,646 - 18,357,761 (-)Ensembl
ChiLan1.0NW_00495543418,312,646 - 18,357,753 (-)NCBIChiLan1.0ChiLan1.0
PSIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211109,043,050 - 109,090,002 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19109,049,057 - 109,095,949 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0915,280,947 - 15,327,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1915,784,740 - 15,831,449 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl915,784,740 - 15,831,449 (-)EnsemblpanPan2panpan1.1
PSIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11135,746,064 - 35,788,473 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1135,747,341 - 35,789,110 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1134,390,775 - 34,437,103 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01136,648,900 - 36,657,415 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1136,655,123 - 36,657,665 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11135,350,549 - 35,396,865 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01135,141,417 - 35,187,689 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01135,799,567 - 35,846,055 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Psip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947150,438,959 - 150,488,118 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365398,892,841 - 8,940,871 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365398,894,285 - 8,940,831 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1207,173,540 - 207,214,773 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11207,173,264 - 207,216,437 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21230,981,479 - 231,024,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11264,086,611 - 64,137,298 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1264,087,189 - 64,140,661 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603852,279,543 - 52,330,223 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473619,618,417 - 19,665,896 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Psip1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1170,286,741 - 70,318,598 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Psip1
248 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:253
Count of miRNA genes:190
Interacting mature miRNAs:220
Transcripts:ENSRNOT00000016130
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)573779642103472210Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat

Markers in Region
AU022012  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22020,419,348 - 20,419,572 (+)MAPPERmRatBN7.2
mRatBN7.2597,847,027 - 97,847,249 (+)MAPPERmRatBN7.2
Rnor_6.02021,813,663 - 21,813,886NCBIRnor6.0
Rnor_6.05101,555,709 - 101,555,930NCBIRnor6.0
Rnor_5.02023,912,313 - 23,912,536UniSTSRnor5.0
Rnor_5.05105,568,322 - 105,568,543UniSTSRnor5.0
RGSC_v3.42021,236,905 - 21,237,128UniSTSRGSC3.4
RGSC_v3.45102,304,459 - 102,304,680UniSTSRGSC3.4
Celera596,399,471 - 96,399,692UniSTS
Celera2021,783,150 - 21,783,373UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map20p11UniSTS
RH134944  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2597,868,158 - 97,868,340 (+)MAPPERmRatBN7.2
Rnor_6.05101,576,837 - 101,577,018NCBIRnor6.0
Rnor_5.05105,589,450 - 105,589,631UniSTSRnor5.0
RGSC_v3.45102,325,587 - 102,325,768UniSTSRGSC3.4
Celera596,420,602 - 96,420,783UniSTS
RH 3.4 Map11140.78UniSTS
Cytogenetic Map5q31UniSTS
RH137948  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22020,419,448 - 20,419,672 (+)MAPPERmRatBN7.2
mRatBN7.2597,847,120 - 97,847,349 (+)MAPPERmRatBN7.2
Rnor_6.05101,555,802 - 101,556,030NCBIRnor6.0
Rnor_5.05105,568,415 - 105,568,643UniSTSRnor5.0
RGSC_v3.45102,304,552 - 102,304,780UniSTSRGSC3.4
Celera596,399,564 - 96,399,792UniSTS
Cytogenetic Map5q31UniSTS
BE118042  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2597,870,730 - 97,870,886 (+)MAPPERmRatBN7.2
Rnor_6.05101,579,409 - 101,579,564NCBIRnor6.0
Rnor_5.05105,592,022 - 105,592,177UniSTSRnor5.0
RGSC_v3.45102,328,159 - 102,328,314UniSTSRGSC3.4
Celera596,423,174 - 96,423,329UniSTS
RH 3.4 Map5745.1UniSTS
Cytogenetic Map5q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001436769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB285525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF339084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF372090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016130   ⟹   ENSRNOP00000016130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5102,892,932 - 102,924,573 (-)Ensembl
mRatBN7.2 Ensembl597,847,015 - 97,878,738 (-)Ensembl
Rnor_6.0 Ensembl5101,555,694 - 101,588,001 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082239   ⟹   ENSRNOP00000068629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5102,898,614 - 102,925,170 (-)Ensembl
mRatBN7.2 Ensembl597,853,035 - 97,879,257 (-)Ensembl
Rnor_6.0 Ensembl5101,561,716 - 101,588,598 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094774   ⟹   ENSRNOP00000077371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5102,895,414 - 102,924,670 (-)Ensembl
mRatBN7.2 Ensembl597,849,495 - 97,878,757 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108041   ⟹   ENSRNOP00000094095
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl597,847,519 - 97,879,257 (-)Ensembl
RefSeq Acc Id: NM_175765   ⟹   NP_786941
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,893,436 - 102,924,670 (-)NCBI
mRatBN7.2597,847,517 - 97,878,757 (-)NCBI
Rnor_6.05101,556,198 - 101,588,098 (-)NCBI
Rnor_5.05105,568,304 - 105,601,260 (-)NCBI
RGSC_v3.45102,304,948 - 102,336,608 (-)RGD
Celera596,399,960 - 96,431,195 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238353   ⟹   XP_006238415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,892,929 - 102,925,191 (-)NCBI
mRatBN7.2597,847,010 - 97,878,757 (-)NCBI
Rnor_6.05101,555,909 - 101,588,659 (-)NCBI
Rnor_5.05105,568,304 - 105,601,260 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008763779   ⟹   XP_008762001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,898,944 - 102,925,191 (-)NCBI
mRatBN7.2597,853,025 - 97,879,280 (-)NCBI
Rnor_6.05101,561,706 - 101,588,657 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593365   ⟹   XP_017448854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,898,944 - 102,925,191 (-)NCBI
mRatBN7.2597,853,025 - 97,878,757 (-)NCBI
Rnor_6.05101,561,706 - 101,588,658 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593366   ⟹   XP_017448855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,898,944 - 102,925,191 (-)NCBI
mRatBN7.2597,853,025 - 97,878,757 (-)NCBI
Rnor_6.05101,561,706 - 101,588,657 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109886   ⟹   XP_038965814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,898,944 - 102,925,191 (-)NCBI
mRatBN7.2597,853,025 - 97,878,757 (-)NCBI
RefSeq Acc Id: XM_039109887   ⟹   XP_038965815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,898,944 - 102,925,191 (-)NCBI
mRatBN7.2597,853,025 - 97,878,757 (-)NCBI
RefSeq Acc Id: XM_039109888   ⟹   XP_038965816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,898,944 - 102,925,191 (-)NCBI
mRatBN7.2597,853,025 - 97,878,757 (-)NCBI
RefSeq Acc Id: XM_063287634   ⟹   XP_063143704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85102,892,929 - 102,925,191 (-)NCBI
RefSeq Acc Id: NP_786941   ⟸   NM_175765
- UniProtKB: Q812D1 (UniProtKB/Swiss-Prot),   Q7TNY0 (UniProtKB/Swiss-Prot),   F1SW39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238415   ⟸   XM_006238353
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008762001   ⟸   XM_008763779
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017448854   ⟸   XM_017593365
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017448855   ⟸   XM_017593366
- Peptide Label: isoform X8
- Sequence:
Ensembl Acc Id: ENSRNOP00000016130   ⟸   ENSRNOT00000016130
Ensembl Acc Id: ENSRNOP00000068629   ⟸   ENSRNOT00000082239
RefSeq Acc Id: XP_038965814   ⟸   XM_039109886
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038965815   ⟸   XM_039109887
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038965816   ⟸   XM_039109888
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000094095   ⟸   ENSRNOT00000108041
Ensembl Acc Id: ENSRNOP00000077371   ⟸   ENSRNOT00000094774
RefSeq Acc Id: XP_063143704   ⟸   XM_063287634
- Peptide Label: isoform X2
Protein Domains
PWWP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q812D1-F1-model_v2 AlphaFold Q812D1 1-528 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693823
Promoter ID:EPDNEW_R4344
Type:initiation region
Name:Psip1_1
Description:PC4 and SFRS1 interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05101,588,622 - 101,588,682EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631439 AgrOrtholog
BioCyc Gene G2FUF-40874 BioCyc
Ensembl Genes ENSRNOG00000011498 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000016130 ENTREZGENE
  ENSRNOT00000082239 ENTREZGENE
  ENSRNOT00000094774 ENTREZGENE
Gene3D-CATH 1.20.930.10 UniProtKB/Swiss-Prot
  2.30.30.140 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7317952 IMAGE-MGC_LOAD
InterPro HIVI-bd_sf UniProtKB/Swiss-Prot
  LEDGF_IBD UniProtKB/Swiss-Prot
  PWWP_dom UniProtKB/Swiss-Prot
  TFIIS/LEDGF_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:313323 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105284 IMAGE-MGC_LOAD
NCBI Gene 313323 ENTREZGENE
PANTHER HEPATOMA-DERIVED GROWTH FACTOR-RELATED UniProtKB/Swiss-Prot
  PC4 AND SFRS1-INTERACTING PROTEIN UniProtKB/Swiss-Prot
Pfam LEDGF UniProtKB/Swiss-Prot
  PWWP UniProtKB/Swiss-Prot
PhenoGen Psip1 PhenoGen
PRINTS TREACLE UniProtKB/Swiss-Prot
PROSITE PWWP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011498 RatGTEx
SMART PWWP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF140576 UniProtKB/Swiss-Prot
  Tudor/PWWP/MBT UniProtKB/Swiss-Prot
UniProt A0A0G2JTA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y7G7_RAT UniProtKB/TrEMBL
  A0A8I6AK62 ENTREZGENE
  F1SW39 ENTREZGENE, UniProtKB/TrEMBL
  F7FJ14 ENTREZGENE, UniProtKB/TrEMBL
  PSIP1_RAT UniProtKB/Swiss-Prot
  Q566D6 ENTREZGENE, UniProtKB/TrEMBL
  Q7TNY0 ENTREZGENE
  Q812D1 ENTREZGENE
UniProt Secondary Q7TNY0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-13 Psip1  PC4 and SRSF1 interacting protein 1  Psip1  PC4 and SFRS1 interacting protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Psip1  PC4 and SFRS1 interacting protein 1  Psip2  PC4 and SFRS1 interacting protein 2  Symbol and Name updated 1299863 APPROVED
2004-02-11 Psip2  PC4 and SFRS1 interacting protein 2  Ledgf  lens epithelium-derived growth factor  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the ocular tissues, lens, cornea, iris, ciliary body, and retina 724425