Gene: Kcnmb2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2) Rattus norvegicus
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Symbol:
Kcnmb2
Name:
potassium calcium-activated channel subfamily M regulatory beta subunit 2
RGD ID:
631398
Description:
Enables potassium channel activity. Predicted to be involved in detection of calcium ion; neuronal action potential; and potassium ion transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Orthologous to human KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
BK channel subunit beta-2; BKbeta2; calcium-activated potassium channel beta 2; calcium-activated potassium channel subunit beta-2; calcium-activated potassium channel, subfamily M subunit beta-2; charybdotoxin receptor subunit beta-2; k(VCA)beta-2; Kcmb2; maxi K channel subunit beta-2; potassium channel subfamily M regulatory beta subunit 2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; rbeta3; slo-beta-2
RGD Orthologs
Alliance Orthologs
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Kcnmb2 (potassium large conductance calcium-activated channel, subfamily M, beta member 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Kcnmb2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Kcnmb2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Kcnmb2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Kcnmb2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
UPF3A (UPF3A regulator of nonsense mediated mRNA decay)
HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Kcnmb2 (potassium large conductance calcium-activated channel, subfamily M, beta member 2)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2)
Alliance
DIOPT (HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
kcnmb2 (potassium large conductance calcium-activated channel, subfamily M, beta member 2)
Alliance
DIOPT (InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
si:ch211-247n2.1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
kcnmb2
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Candidate Gene For:
Cm49
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 116,598,511 - 116,903,886 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 116,599,387 - 116,903,854 (+) Ensembl GRCr8 mRatBN7.2 2 114,670,027 - 114,975,374 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 114,935,976 - 114,975,173 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 2 121,544,723 - 121,583,077 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 119,657,353 - 119,695,703 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 114,367,754 - 114,404,847 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 118,276,298 - 118,585,321 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 118,546,829 - 118,586,699 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 2 138,219,013 - 138,256,373 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 118,363,702 - 118,401,375 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 110,048,414 - 110,085,833 (+) NCBI Celera RGSC_v3.1 2 118,308,663 - 118,346,337 (+) NCBI Cytogenetic Map 2 q24 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Kcnmb2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Kcnmb2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcnmb2 Rat 1,2-dichloroethane decreases expression ISO Kcnmb2 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of KCNMB2 mRNA CTD PMID:28960355 Kcnmb2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Kcnmb2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcnmb2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Kcnmb2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcnmb2 Rat 2,3',4,4',5-Pentachlorobiphenyl decreases expression ISO Kcnmb2 (Mus musculus) 6480464 2,3',4,4',5-pentachlorobiphenyl results in decreased expression of KCNMB2 mRNA CTD PMID:31388691 Kcnmb2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KCNMB2 mRNA CTD PMID:32109520 Kcnmb2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Kcnmb2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcnmb2 Rat 4,4'-sulfonyldiphenol increases methylation ISO KCNMB2 (Homo sapiens) 6480464 bisphenol S results in increased methylation of KCNMB2 gene CTD PMID:31601247 Kcnmb2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of KCNMB2 mRNA CTD PMID:24780913 Kcnmb2 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of KCNMB2 mRNA CTD PMID:30047161 Kcnmb2 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of KCNMB2 mRNA CTD PMID:28959563 Kcnmb2 Rat aflatoxin B1 increases methylation ISO KCNMB2 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of KCNMB2 intron CTD PMID:30157460 Kcnmb2 Rat Aflatoxin B2 alpha increases methylation ISO KCNMB2 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of KCNMB2 intron CTD PMID:30157460 Kcnmb2 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of KCNMB2 mRNA CTD PMID:30047161 Kcnmb2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of KCNMB2 mRNA CTD PMID:16483693 Kcnmb2 Rat benzo[a]pyrene affects methylation ISO KCNMB2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of KCNMB2 5' UTR CTD PMID:27901495 Kcnmb2 Rat benzo[a]pyrene decreases methylation ISO KCNMB2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of KCNMB2 promoter CTD PMID:27901495 Kcnmb2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of KCNMB2 mRNA CTD PMID:25181051|PMID:34947998 Kcnmb2 Rat bisphenol A decreases methylation ISO KCNMB2 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of KCNMB2 gene CTD PMID:31601247 Kcnmb2 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of KCNMB2 gene CTD PMID:28505145 Kcnmb2 Rat bisphenol F increases expression ISO KCNMB2 (Homo sapiens) 6480464 bisphenol F results in increased expression of KCNMB2 mRNA CTD PMID:33476716 Kcnmb2 Rat bisphenol F decreases methylation ISO KCNMB2 (Homo sapiens) 6480464 bisphenol F results in decreased methylation of KCNMB2 gene CTD PMID:31601247 Kcnmb2 Rat Butylbenzyl phthalate increases methylation ISO Kcnmb2 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of KCNMB2 intron CTD PMID:28392331 Kcnmb2 Rat carbon nanotube decreases expression ISO Kcnmb2 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of KCNMB2 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Kcnmb2 Rat CGP 52608 multiple interactions ISO KCNMB2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to KCNMB2 gene] CTD PMID:28238834 Kcnmb2 Rat chlorpyrifos increases methylation EXP 6480464 Chlorpyrifos results in increased methylation of KCNMB2 gene CTD PMID:32905263 Kcnmb2 Rat chlorpyrifos decreases expression ISO Kcnmb2 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of KCNMB2 mRNA CTD PMID:37019170 Kcnmb2 Rat Cuprizon affects expression EXP 6480464 Cuprizone affects the expression of KCNMB2 mRNA CTD PMID:26577399 Kcnmb2 Rat curcumin decreases expression ISO KCNMB2 (Homo sapiens) 6480464 Curcumin results in decreased expression of KCNMB2 mRNA CTD PMID:17198877 Kcnmb2 Rat cyclosporin A decreases methylation ISO KCNMB2 (Homo sapiens) 6480464 Cyclosporine results in decreased methylation of KCNMB2 promoter CTD PMID:27989131 Kcnmb2 Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of KCNMB2 mRNA CTD PMID:31464424 Kcnmb2 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of KCNMB2 mRNA CTD PMID:30047161 Kcnmb2 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNMB2 mRNA CTD PMID:20360939 Kcnmb2 Rat okadaic acid decreases expression ISO KCNMB2 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of KCNMB2 mRNA CTD PMID:38832940 Kcnmb2 Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of KCNMB2 mRNA CTD PMID:32680482 Kcnmb2 Rat PCB138 multiple interactions ISO Kcnmb2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Kcnmb2 Rat perfluorohexanesulfonic acid increases expression ISO Kcnmb2 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of KCNMB2 mRNA CTD PMID:37315490 Kcnmb2 Rat phenethyl caffeate multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNMB2 mRNA CTD PMID:20360939 Kcnmb2 Rat progesterone decreases expression ISO KCNMB2 (Homo sapiens) 6480464 Progesterone results in decreased expression of KCNMB2 mRNA CTD PMID:21795739 Kcnmb2 Rat rotenone increases expression ISO KCNMB2 (Homo sapiens) 6480464 Rotenone results in increased expression of KCNMB2 mRNA CTD PMID:29955902 Kcnmb2 Rat sodium arsenite decreases expression ISO Kcnmb2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of KCNMB2 mRNA CTD PMID:37682722 Kcnmb2 Rat sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of KCNMB2 mRNA CTD PMID:30047161 Kcnmb2 Rat Tesaglitazar decreases expression EXP 6480464 tesaglitazar results in decreased expression of KCNMB2 mRNA CTD PMID:21515302 Kcnmb2 Rat titanium dioxide decreases expression ISO Kcnmb2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of KCNMB2 mRNA CTD PMID:23557971 Kcnmb2 Rat titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of KCNMB2 mRNA CTD PMID:30012374 Kcnmb2 Rat troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of KCNMB2 mRNA CTD PMID:21515302 Kcnmb2 Rat tunicamycin increases expression ISO Kcnmb2 (Mus musculus) 6480464 Tunicamycin results in increased expression of KCNMB2 mRNA CTD PMID:17127020 Kcnmb2 Rat valproic acid increases expression ISO KCNMB2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of KCNMB2 mRNA CTD PMID:27188386