Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ppm1f | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Ppm1f (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PPM1F mRNA | CTD | PMID:22206623 | Ppm1f | Rat | 17beta-estradiol | affects expression | ISO | PPM1F (Homo sapiens) | 6480464 | Estradiol affects the expression of PPM1F mRNA | CTD | PMID:22574217 | Ppm1f | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PPM1F mRNA | CTD | PMID:22298810 | Ppm1f | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PPM1F mRNA | CTD | PMID:34747641 | Ppm1f | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ppm1f (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PPM1F mRNA | CTD | PMID:21570461 | Ppm1f | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Ppm1f (Mus musculus) | 6480464 | bisphenol S affects the methylation of PPM1F gene | CTD | PMID:31683443 | Ppm1f | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | Fenretinide results in increased expression of PPM1F mRNA | CTD | PMID:28973697 | Ppm1f | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PPM1F mRNA | CTD | PMID:24780913 and PMID:30047161 | Ppm1f | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of PPM1F mRNA | CTD | PMID:31881176 | Ppm1f | Rat | acrylamide | decreases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PPM1F mRNA | CTD | PMID:32763439 | Ppm1f | Rat | aflatoxin B1 | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PPM1F mRNA | CTD | PMID:19770486 | Ppm1f | Rat | aflatoxin B1 | increases methylation | ISO | PPM1F (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of PPM1F gene | CTD | PMID:27153756 | Ppm1f | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PPM1F mRNA | CTD | PMID:30047161 | Ppm1f | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PPM1F mRNA | CTD | PMID:16483693 | Ppm1f | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of PPM1F mRNA | CTD | PMID:30779732 | Ppm1f | Rat | aristolochic acid A | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PPM1F mRNA | CTD | PMID:33212167 | Ppm1f | Rat | benzatropine | decreases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Benztropine results in decreased expression of PPM1F protein | CTD | PMID:34122009 | Ppm1f | Rat | benzo[a]pyrene | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of PPM1F mRNA] | CTD | PMID:19152381 | Ppm1f | Rat | benzo[a]pyrene | decreases methylation | ISO | PPM1F (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PPM1F 3' UTR and Benzo(a)pyrene results in decreased methylation of PPM1F 5' UTR | CTD | PMID:27901495 | Ppm1f | Rat | benzo[a]pyrene | affects methylation | ISO | PPM1F (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PPM1F promoter | CTD | PMID:27901495 | Ppm1f | Rat | benzo[a]pyrene | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PPM1F mRNA | CTD | PMID:22610609 | Ppm1f | Rat | benzo[a]pyrene | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PPM1F mRNA | CTD | PMID:19152381 | Ppm1f | Rat | beta-naphthoflavone | decreases expression | ISO | PPM1F (Homo sapiens) | 6480464 | beta-Naphthoflavone results in decreased expression of PPM1F mRNA | CTD | PMID:32858204 | Ppm1f | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PPM1F mRNA | CTD | PMID:30816183 | Ppm1f | Rat | bisphenol A | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | bisphenol A results in increased expression of PPM1F mRNA | CTD | PMID:33221593 | Ppm1f | Rat | Bisphenol B | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | bisphenol B results in increased expression of PPM1F protein | CTD | PMID:34186270 | Ppm1f | Rat | bisphenol F | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of PPM1F gene | CTD | PMID:31601247 | Ppm1f | Rat | bisphenol F | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | bisphenol F results in increased expression of PPM1F mRNA | CTD | PMID:38685157 | Ppm1f | Rat | bisphenol F | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PPM1F protein | CTD | PMID:34186270 | Ppm1f | Rat | bisphenol F | decreases methylation | ISO | PPM1F (Homo sapiens) | 6480464 | bisphenol F results in decreased methylation of PPM1F gene | CTD | PMID:31601247 | Ppm1f | Rat | bortezomib | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Bortezomib results in increased expression of PPM1F mRNA | CTD | PMID:20977926 | Ppm1f | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of PPM1F mRNA | CTD | PMID:19167457 | Ppm1f | Rat | cadmium dichloride | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PPM1F mRNA | CTD | PMID:38568856 | Ppm1f | Rat | caffeine | decreases phosphorylation | ISO | PPM1F (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PPM1F protein | CTD | PMID:35688186 | Ppm1f | Rat | carbon nanotube | decreases expression | ISO | Ppm1f (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of PPM1F mRNA | CTD | PMID:25554681 | Ppm1f | Rat | CGP 52608 | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PPM1F gene] | CTD | PMID:28238834 | Ppm1f | Rat | cisplatin | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | Cisplatin promotes the reaction [jinfukang results in increased expression of PPM1F mRNA] and jinfukang promotes the reaction [Cisplatin results in increased expression of PPM1F mRNA] | CTD | PMID:27392435 | Ppm1f | Rat | copper(II) chloride | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | cupric chloride results in increased expression of PPM1F mRNA | CTD | PMID:38568856 | Ppm1f | Rat | Cuprizon | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | [Cuprizone co-treated with Haloperidol] results in decreased expression of PPM1F protein | CTD | PMID:34122009 | Ppm1f | Rat | diazinon | decreases methylation | ISO | PPM1F (Homo sapiens) | 6480464 | Diazinon results in decreased methylation of PPM1F gene | CTD | PMID:22964155 | Ppm1f | Rat | dibenz[a,h]anthracene | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | Ppm1f | Rat | folic acid | multiple interactions | ISO | Ppm1f (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PPM1F mRNA | CTD | PMID:22206623 | Ppm1f | Rat | fulvestrant | increases methylation | ISO | PPM1F (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of PPM1F gene | CTD | PMID:31601247 | Ppm1f | Rat | fulvestrant | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of PPM1F gene | CTD | PMID:31601247 | Ppm1f | Rat | haloperidol | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | [Cuprizone co-treated with Haloperidol] results in decreased expression of PPM1F protein | CTD | PMID:34122009 | Ppm1f | Rat | ivermectin | decreases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PPM1F protein | CTD | PMID:32959892 | Ppm1f | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of PPM1F mRNA | CTD | PMID:30047161 | Ppm1f | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of PPM1F gene | CTD | PMID:35440735 | Ppm1f | Rat | nickel dichloride | decreases expression | ISO | PPM1F (Homo sapiens) | 6480464 | nickel chloride results in decreased expression of PPM1F mRNA | CTD | PMID:17312168 | Ppm1f | Rat | ozone | multiple interactions | ISO | Ppm1f (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PPM1F mRNA | CTD | PMID:34911549 | Ppm1f | Rat | ozone | multiple interactions | ISO | PPM1F (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of PPM1F mRNA | CTD | PMID:35430440 | Ppm1f | Rat | serpentine asbestos | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Asbestos and Serpentine results in increased expression of PPM1F mRNA | CTD | PMID:21148743 | Ppm1f | Rat | silicon dioxide | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PPM1F mRNA and Silicon Dioxide results in increased expression of PPM1F mRNA | CTD | PMID:25351596 and PMID:25895662 | Ppm1f | Rat | sodium arsenite | increases expression | ISO | PPM1F (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PPM1F mRNA | CTD | PMID:34032870 | Ppm1f | Rat | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of PPM1F mRNA | CTD | PMID:21515302 | Ppm1f | Rat | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of PPM1F mRNA | CTD | PMID:12734012 | Ppm1f | Rat | triphenyl phosphate | affects expression | ISO | PPM1F (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PPM1F mRNA | CTD | PMID:37042841 | Ppm1f | Rat | trovafloxacin | increases expression | ISO | Ppm1f (Mus musculus) | 6480464 | trovafloxacin results in increased expression of PPM1F mRNA | CTD | PMID:35537566 | Ppm1f | Rat | urethane | decreases expression | ISO | PPM1F (Homo sapiens) | 6480464 | Urethane results in decreased expression of PPM1F mRNA | CTD | PMID:28818685 | Ppm1f | Rat | valproic acid | affects expression | ISO | Ppm1f (Mus musculus) | 6480464 | Valproic Acid affects the expression of PPM1F mRNA | CTD | PMID:17963808 | Ppm1f | Rat | valproic acid | increases methylation | ISO | PPM1F (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PPM1F gene | CTD | PMID:29154799 | Ppm1f | Rat | vinclozolin | decreases methylation | EXP | | 6480464 | vinclozolin results in decreased methylation of PPM1F gene | CTD | PMID:31682807 | |