Itpkc (inositol-trisphosphate 3-kinase C) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Itpkc (inositol-trisphosphate 3-kinase C) Rattus norvegicus
Analyze
Symbol: Itpkc
Name: inositol-trisphosphate 3-kinase C
RGD ID: 631336
Description: Enables kinase activity. Predicted to be involved in cellular response to calcium ion; inositol phosphate biosynthetic process; and phosphatidylinositol phosphate biosynthetic process. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human ITPKC (inositol-trisphosphate 3-kinase C); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; allethrin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inositol 1,4,5-trisphosphate 3-kinase C; insP 3-kinase C; IP3 3-kinase C; IP3K C; IP3K-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,628,606 - 91,650,182 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl191,628,608 - 91,653,350 (-)EnsemblGRCr8
mRatBN7.2182,500,957 - 82,522,533 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,500,957 - 82,522,779 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx187,904,062 - 87,925,518 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,390,711 - 96,412,265 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,659,928 - 89,681,384 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,018,857 - 84,040,433 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,018,859 - 84,040,433 (-)Ensemblrn6Rnor6.0
Rnor_5.0185,229,796 - 85,251,373 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4182,284,846 - 82,306,422 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,913,801 - 76,935,408 (-)NCBICelera
RGSC_v3.1182,362,958 - 82,384,779 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
actinomycin D  (ISO)
allethrin  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
Diisodecyl phthalate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gardiquimod  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (EXP)
methyl methanesulfonate  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
protein kinase inhibitor  (ISO)
pyrethrins  (EXP)
quercetin  (ISO)
ranitidine  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
nuclear speck  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm. Nalaskowski MM, etal., J Biol Chem 2003 May 30;278(22):19765-76.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Immune-related genes STIM1, ITPKC and PELI1 polymorphisms are associated with risk of colorectal cancer. Zhu L, etal., Eur J Cancer Prev. 2021 Sep 1;30(5):357-363. doi: 10.1097/CEJ.0000000000000641.
Additional References at PubMed
PMID:14517551  


Genomics

Comparative Map Data
Itpkc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,628,606 - 91,650,182 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl191,628,608 - 91,653,350 (-)EnsemblGRCr8
mRatBN7.2182,500,957 - 82,522,533 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,500,957 - 82,522,779 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx187,904,062 - 87,925,518 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,390,711 - 96,412,265 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,659,928 - 89,681,384 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,018,857 - 84,040,433 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,018,859 - 84,040,433 (-)Ensemblrn6Rnor6.0
Rnor_5.0185,229,796 - 85,251,373 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4182,284,846 - 82,306,422 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,913,801 - 76,935,408 (-)NCBICelera
RGSC_v3.1182,362,958 - 82,384,779 (-)NCBI
Cytogenetic Map1q21NCBI
ITPKC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,717,112 - 40,740,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,717,112 - 40,740,860 (+)Ensemblhg38GRCh38
GRCh371941,223,017 - 41,246,765 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,914,848 - 45,938,605 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341945,914,847 - 45,938,603NCBI
Celera1938,023,433 - 38,047,190 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,656,377 - 37,680,128 (+)NCBIHuRef
CHM1_11941,222,687 - 41,246,445 (+)NCBICHM1_1
T2T-CHM13v2.01943,537,804 - 43,561,551 (+)NCBIT2T-CHM13v2.0
Itpkc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39726,906,595 - 26,928,042 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl726,906,597 - 26,928,086 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38727,207,170 - 27,228,617 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,207,172 - 27,228,661 (-)Ensemblmm10GRCm38
MGSCv37727,992,189 - 28,013,616 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36726,915,930 - 26,937,357 (-)NCBIMGSCv36mm8
Celera721,784,090 - 21,805,517 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map715.85NCBI
Itpkc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578598,351 - 614,081 (-)Ensembl
ChiLan1.0NW_004955578597,105 - 614,081 (-)NCBIChiLan1.0ChiLan1.0
ITPKC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,976,610 - 46,999,354 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11948,846,416 - 48,870,305 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01937,761,221 - 37,785,118 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,267,598 - 46,292,236 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,267,754 - 46,290,935 (+)EnsemblpanPan2panpan1.1
ITPKC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,037,833 - 113,053,877 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,039,093 - 113,053,738 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1112,440,273 - 112,456,324 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01113,636,482 - 113,652,541 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,636,486 - 113,652,393 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,196,051 - 113,212,102 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,827,654 - 112,843,748 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,821,972 - 113,838,031 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Itpkc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,578,574 - 14,594,784 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366613,006,505 - 3,022,823 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366613,006,506 - 3,023,355 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPKC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,943,357 - 48,961,438 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1648,943,207 - 48,962,101 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,627,778 - 44,646,058 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITPKC
(Chlorocebus sabaeus - green monkey)		 No map positions available.
Itpkc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624925645,385 - 662,580 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624925645,528 - 663,768 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Itpkc
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12168,714,290 - 168,736,017 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Itpkc
86 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:343
Count of miRNA genes:194
Interacting mature miRNAs:239
Transcripts:ENSRNOT00000018696
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat

Markers in Region
RH132115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,501,182 - 82,501,364 (+)MAPPERmRatBN7.2
Rnor_6.0184,019,083 - 84,019,264NCBIRnor6.0
Rnor_5.0185,230,022 - 85,230,203UniSTSRnor5.0
RGSC_v3.4182,285,072 - 82,285,253UniSTSRGSC3.4
Celera176,914,027 - 76,914,208UniSTS
RH 3.4 Map1825.7UniSTS
Cytogenetic Map1q21UniSTS
RH142788  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8191,637,331 - 91,637,532 (+)Marker Load Pipeline
mRatBN7.2182,509,682 - 82,509,883 (+)MAPPERmRatBN7.2
Rnor_6.0184,027,583 - 84,027,783NCBIRnor6.0
Rnor_5.0185,238,522 - 85,238,722UniSTSRnor5.0
RGSC_v3.4182,293,572 - 82,293,772UniSTSRGSC3.4
Celera176,922,557 - 76,922,758UniSTS
RH 3.4 Map1827.7UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018696   ⟹   ENSRNOP00000018696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl191,628,608 - 91,650,074 (-)Ensembl
mRatBN7.2 Ensembl182,500,957 - 82,522,425 (-)Ensembl
Rnor_6.0 Ensembl184,018,859 - 84,040,433 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100648   ⟹   ENSRNOP00000084385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl191,628,608 - 91,650,428 (-)Ensembl
mRatBN7.2 Ensembl182,500,959 - 82,522,779 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158132   ⟹   ENSRNOP00000100160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl191,628,608 - 91,653,350 (-)Ensembl
RefSeq Acc Id: NM_178094   ⟹   NP_835195
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8191,628,606 - 91,650,182 (-)NCBI
mRatBN7.2182,500,957 - 82,522,533 (-)NCBI
Rnor_6.0184,018,857 - 84,040,433 (-)NCBI
Rnor_5.0185,229,796 - 85,251,373 (-)NCBI
RGSC_v3.4182,284,846 - 82,306,422 (-)RGD
Celera176,913,801 - 76,935,408 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_835195 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO20335 (Get FASTA)   NCBI Sequence Viewer  
  CAD29464 (Get FASTA)   NCBI Sequence Viewer  
  EDM07966 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000084385
  ENSRNOP00000084385.1
GenBank Protein Q80ZG2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_835195   ⟸   NM_178094
- UniProtKB: Q80ZG2 (UniProtKB/Swiss-Prot),   A6J9B8 (UniProtKB/TrEMBL),   A0A8L2UJ86 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018696   ⟸   ENSRNOT00000018696
Ensembl Acc Id: ENSRNOP00000084385   ⟸   ENSRNOT00000100648
Ensembl Acc Id: ENSRNOP00000100160   ⟸   ENSRNOT00000158132

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80ZG2-F1-model_v2 AlphaFold Q80ZG2 1-678 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689845
Promoter ID:EPDNEW_R370
Type:single initiation site
Name:Itpkc_1
Description:inositol-trisphosphate 3-kinase C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0184,040,349 - 84,040,409EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631336 AgrOrtholog
BioCyc Gene G2FUF-60320 BioCyc
BioCyc Pathway PWY-6361 [1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)] BioCyc
  PWY-6362 [1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)] BioCyc
  PWY-6364 [D-myo-inositol (1,3,4)-trisphosphate biosynthesis] BioCyc
BioCyc Pathway Image PWY-6361 BioCyc
  PWY-6362 BioCyc
  PWY-6364 BioCyc
Ensembl Genes ENSRNOG00000013945 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000100648 ENTREZGENE
  ENSRNOT00000100648.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.470.160 UniProtKB/Swiss-Prot
InterPro IPK UniProtKB/Swiss-Prot
  IPK_sf UniProtKB/Swiss-Prot
KEGG Report rno:308451 UniProtKB/Swiss-Prot
NCBI Gene 308451 ENTREZGENE
PANTHER INOSITOL-TRISPHOSPHATE 3-KINASE C UniProtKB/Swiss-Prot
  PTHR12400 UniProtKB/Swiss-Prot
Pfam IPK UniProtKB/Swiss-Prot
PhenoGen Itpkc PhenoGen
RatGTEx ENSRNOG00000013945 RatGTEx
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot
UniProt A0A8L2UJ86 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LFA3_RAT UniProtKB/TrEMBL
  A6J9B8 ENTREZGENE, UniProtKB/TrEMBL
  IP3KC_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Itpkc  inositol-trisphosphate 3-kinase C  Itpkc  inositol 1,4,5-trisphosphate 3-kinase C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Itpkc  inositol 1,4,5-trisphosphate 3-kinase C      Symbol and Name status set to approved 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in heart, brain, and testis with strongest expression in epidermal tissue 633165