Obscn (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF) - Rat Genome Database

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Gene: Obscn (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF) Rattus norvegicus
Analyze
Symbol: Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
RGD ID: 631335
Description: Predicted to enable several functions, including cytoskeletal protein binding activity; phosphatidylinositol phosphate binding activity; and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in M band and Z disc. Orthologous to human OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical LOC287353; LOC108352087; LOC287353; Obscnl; obscurin; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF-like; obscurin-like; RGD1305774
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81044,273,686 - 44,419,275 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1044,288,866 - 44,419,297 (-)EnsemblGRCr8
mRatBN7.21043,774,113 - 43,919,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1043,789,293 - 43,919,723 (-)EnsemblmRatBN7.2
Rnor_6.01045,353,185 - 45,483,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,338,009 - 45,481,008 (-)Ensemblrn6Rnor6.0
Rnor_5.01045,094,419 - 45,240,049 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41045,286,791 - 45,432,832 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1043,040,464 - 43,184,409 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cocaine  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP,ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
glucose  (ISO)
glyphosate  (EXP,ISO)
GSK-J4  (ISO)
hydralazine  (ISO)
ivermectin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pioglitazone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
tebuconazole  (ISO)
testosterone  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
extracellular space  (ISO)
intercalated disc  (ISO)
M band  (IBA,IDA,ISO)
nucleus  (IEA)
plasma membrane  (ISO)
sarcolemma  (IBA,ISO)
sarcomere  (IDA)
Z disc  (IBA,IDA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Obscurin: a multitasking muscle giant. Kontrogianni-Konstantopoulos A and Bloch RJ, J Muscle Res Cell Motil. 2005;26(6-8):419-26.
3. Obscurin is a ligand for small ankyrin 1 in skeletal muscle. Kontrogianni-Konstantopoulos A, etal., Mol Biol Cell 2003 Mar;14(3):1138-48.
4. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts. Makarenko I, etal., Circ Res. 2004 Oct 1;95(7):708-16. Epub 2004 Sep 2.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11717165   PMID:15013951   PMID:15314079   PMID:16205939   PMID:17012262   PMID:18219491   PMID:18477606   PMID:18782775   PMID:19002483   PMID:19403693   PMID:19605563   PMID:22416964  
PMID:23392350   PMID:24516603   PMID:28826662   PMID:38127465  


Genomics

Comparative Map Data
Obscn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81044,273,686 - 44,419,275 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1044,288,866 - 44,419,297 (-)EnsemblGRCr8
mRatBN7.21043,774,113 - 43,919,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1043,789,293 - 43,919,723 (-)EnsemblmRatBN7.2
Rnor_6.01045,353,185 - 45,483,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,338,009 - 45,481,008 (-)Ensemblrn6Rnor6.0
Rnor_5.01045,094,419 - 45,240,049 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41045,286,791 - 45,432,832 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1043,040,464 - 43,184,409 (-)NCBICelera
Cytogenetic Map10q22NCBI
OBSCN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381228,208,044 - 228,378,876 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1228,208,044 - 228,378,876 (+)Ensemblhg38GRCh38
GRCh371228,395,745 - 228,566,577 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,462,484 - 226,633,198 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341224,702,595 - 224,855,685NCBI
Celera1201,585,880 - 201,756,652 (+)NCBICelera
Cytogenetic Map1q42.13NCBI
HuRef1198,910,669 - 199,081,449 (+)NCBIHuRef
CHM1_11229,668,122 - 229,838,939 (+)NCBICHM1_1
T2T-CHM13v2.01227,396,836 - 227,567,714 (+)NCBIT2T-CHM13v2.0
Obscn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,885,082 - 59,027,201 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,885,082 - 59,029,996 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381158,994,256 - 59,136,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,994,256 - 59,139,170 (-)Ensemblmm10GRCm38
MGSCv371158,807,758 - 58,949,877 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361158,810,527 - 58,824,805 (-)NCBIMGSCv36mm8
Celera1163,760,680 - 63,901,312 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.4NCBI
Obscn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955581148,571 - 265,062 (-)NCBIChiLan1.0ChiLan1.0
OBSCN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2121,227,144 - 21,396,608 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1121,165,336 - 21,378,948 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01203,605,558 - 203,781,491 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11208,821,882 - 208,992,327 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1208,825,607 - 208,992,246 (+)EnsemblpanPan2panpan1.1
OBSCN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.114664,404 - 782,376 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha14368,668 - 495,174 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.014380,493 - 503,404 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.114566,842 - 694,225 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.014327,479 - 475,088 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.014337,710 - 460,914 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101962737
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721387,601,725 - 87,686,594 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936864619 - 33,574 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OBSCN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,285,488 - 51,534,236 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1251,317,538 - 51,534,246 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,786,998 - 53,794,594 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OBSCN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,356,567 - 1,520,517 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl251,366,179 - 1,514,668 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660551,236,221 - 1,403,869 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Obscn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624937926,090 - 1,060,233 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Obscn
1156 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:345
Count of miRNA genes:199
Interacting mature miRNAs:233
Transcripts:ENSRNOT00000033222, ENSRNOT00000058419
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
RH127871  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21043,789,403 - 43,789,605 (+)MAPPERmRatBN7.2
Rnor_6.01045,353,296 - 45,353,497NCBIRnor6.0
Rnor_5.01045,109,710 - 45,109,911UniSTSRnor5.0
RGSC_v3.41045,302,220 - 45,302,421UniSTSRGSC3.4
Celera1043,055,755 - 43,055,956UniSTS
RH 3.4 Map10501.6UniSTS
Cytogenetic Map10q22UniSTS
RH134278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21043,773,999 - 43,774,199 (+)MAPPERmRatBN7.2
Rnor_6.01045,337,892 - 45,338,091NCBIRnor6.0
Rnor_5.01045,094,306 - 45,094,505UniSTSRnor5.0
RGSC_v3.41045,286,816 - 45,287,015UniSTSRGSC3.4
Celera1043,040,351 - 43,040,550UniSTS
RH 3.4 Map10489.3UniSTS
Cytogenetic Map10q22UniSTS
RH140532  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21043,790,935 - 43,791,040 (+)MAPPERmRatBN7.2
Rnor_6.01045,354,828 - 45,354,932NCBIRnor6.0
Rnor_5.01045,111,242 - 45,111,346UniSTSRnor5.0
RGSC_v3.41045,303,752 - 45,303,856UniSTSRGSC3.4
Celera1043,057,287 - 43,057,391UniSTS
RH 3.4 Map10502.6UniSTS
Cytogenetic Map10q22UniSTS
AA800048  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21043,791,878 - 43,792,014 (+)MAPPERmRatBN7.2
Rnor_6.01045,355,771 - 45,355,906NCBIRnor6.0
Rnor_5.01045,112,185 - 45,112,320UniSTSRnor5.0
RGSC_v3.41045,304,695 - 45,304,830UniSTSRGSC3.4
Celera1043,058,230 - 43,058,365UniSTS
RH 3.4 Map10501.59UniSTS
Cytogenetic Map10q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 67 157 89 88 57 72 57 6 312 172 11 136 65 91 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_017597640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039087250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY167411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000078353   ⟹   ENSRNOP00000074671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1045,338,062 - 45,480,999 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084697   ⟹   ENSRNOP00000069172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1044,288,866 - 44,419,297 (-)Ensembl
mRatBN7.2 Ensembl1043,789,293 - 43,919,723 (-)Ensembl
Rnor_6.0 Ensembl1045,353,714 - 45,480,999 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087926   ⟹   ENSRNOP00000072721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1045,338,009 - 45,481,008 (-)Ensembl
RefSeq Acc Id: XM_039087219   ⟹   XP_038943147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087220   ⟹   XP_038943148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087241   ⟹   XP_038943169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087243   ⟹   XP_038943171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087245   ⟹   XP_038943173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087246   ⟹   XP_038943174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087248   ⟹   XP_038943176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087249   ⟹   XP_038943177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_039087250   ⟹   XP_038943178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
mRatBN7.21043,774,113 - 43,919,716 (-)NCBI
RefSeq Acc Id: XM_063270104   ⟹   XP_063126174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270105   ⟹   XP_063126175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270106   ⟹   XP_063126176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270107   ⟹   XP_063126177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270108   ⟹   XP_063126178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270109   ⟹   XP_063126179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270110   ⟹   XP_063126180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270111   ⟹   XP_063126181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270112   ⟹   XP_063126182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270113   ⟹   XP_063126183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270114   ⟹   XP_063126184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270115   ⟹   XP_063126185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270116   ⟹   XP_063126186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270117   ⟹   XP_063126187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270118   ⟹   XP_063126188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,273,686 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270119   ⟹   XP_063126189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,288,866 - 44,419,275 (-)NCBI
RefSeq Acc Id: XM_063270120   ⟹   XP_063126190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,288,866 - 44,419,275 (-)NCBI
RefSeq Acc Id: XM_063270121   ⟹   XP_063126191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,288,866 - 44,419,274 (-)NCBI
RefSeq Acc Id: XM_063270122   ⟹   XP_063126192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81044,288,866 - 44,419,274 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038943147 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943148 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943169 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943171 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943173 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943174 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943176 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943177 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943178 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126174 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126175 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126176 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126177 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126178 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126179 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126180 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126181 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126182 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126183 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126184 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126185 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126186 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126187 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126188 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126189 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126190 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126191 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126192 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO34127 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069172
  ENSRNOP00000069172.3
Ensembl Acc Id: ENSRNOP00000069172   ⟸   ENSRNOT00000084697
Ensembl Acc Id: ENSRNOP00000072721   ⟸   ENSRNOT00000087926
Ensembl Acc Id: ENSRNOP00000074671   ⟸   ENSRNOT00000078353
RefSeq Acc Id: XP_038943178   ⟸   XM_039087250
- Peptide Label: isoform X24
RefSeq Acc Id: XP_038943174   ⟸   XM_039087246
- Peptide Label: isoform X21
RefSeq Acc Id: XP_038943177   ⟸   XM_039087249
- Peptide Label: isoform X23
RefSeq Acc Id: XP_038943173   ⟸   XM_039087245
- Peptide Label: isoform X20
RefSeq Acc Id: XP_038943176   ⟸   XM_039087248
- Peptide Label: isoform X22
RefSeq Acc Id: XP_038943171   ⟸   XM_039087243
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038943169   ⟸   XM_039087241
- Peptide Label: isoform X18
RefSeq Acc Id: XP_038943148   ⟸   XM_039087220
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038943147   ⟸   XM_039087219
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063126186   ⟸   XM_063270116
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063126182   ⟸   XM_063270112
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063126185   ⟸   XM_063270115
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063126188   ⟸   XM_063270118
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063126179   ⟸   XM_063270109
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063126184   ⟸   XM_063270114
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063126180   ⟸   XM_063270110
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063126181   ⟸   XM_063270111
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063126176   ⟸   XM_063270106
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063126187   ⟸   XM_063270117
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063126178   ⟸   XM_063270108
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063126175   ⟸   XM_063270105
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063126177   ⟸   XM_063270107
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063126183   ⟸   XM_063270113
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063126174   ⟸   XM_063270104
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126190   ⟸   XM_063270120
- Peptide Label: isoform X25
- UniProtKB: A0A0G2JUP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126189   ⟸   XM_063270119
- Peptide Label: isoform X25
- UniProtKB: A0A0G2JUP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126192   ⟸   XM_063270122
- Peptide Label: isoform X27
- UniProtKB: A0A0G2JUP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126191   ⟸   XM_063270121
- Peptide Label: isoform X26
- UniProtKB: A0A0G2JUP3 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631335 AgrOrtholog
BioCyc Gene G2FUF-24915 BioCyc
Ensembl Genes ENSRNOG00000058068 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084697 ENTREZGENE
  ENSRNOT00000084697.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Obscurin/Obscurin-like_Reg UniProtKB/TrEMBL
  Obscurin_SH3 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/TrEMBL
NCBI Gene 338458 ENTREZGENE
PANTHER OBSCURIN LIKE CYTOSKELETAL ADAPTOR 1 UniProtKB/TrEMBL
  SI:DKEY-31G6.6 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/TrEMBL
PhenoGen Obscn PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058068 RatGTEx
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A0G2JUP3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Obscn  obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF  LOC108352087  obscurin-like  Data merged from RGD:11493377 737654 PROVISIONAL
2016-08-02 LOC108352087  obscurin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2015-11-06 Obscn  obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF  Obscnl  obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF-like  Data merged from RGD:1305774 737654 APPROVED
2008-03-18 Obscnl  obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF-like  RGD1305774_predicted  hypothetical LOC287353 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1305774_predicted  hypothetical LOC287353 (predicted)  LOC287353_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC287353_predicted  hypothetical LOC287353 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-11 Obscn  obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF      Symbol and Name status set to approved 625702 APPROVED