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Gene: Acot7 (acyl-CoA thioesterase 7) Rattus norvegicus

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Symbol:

Acot7

Name:

acyl-CoA thioesterase 7

RGD ID:

628856

Description:

Enables fatty acyl-CoA hydrolase activity. Predicted to be involved in fatty acid metabolic process and nucleoside phosphate metabolic process. Predicted to be located in mitochondrial matrix; neuron projection; and neuronal cell body. Predicted to be active in cytosol. Orthologous to human ACOT7 (acyl-CoA thioesterase 7); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ACH1; ACT; Bach; brain acyl-CoA hydrolase; CTE-II; CTE-IIa; CTE-IIb; cytosolic acyl coenzyme A thioester hydrolase; LACH1; long chain acyl-CoA thioester hydrolase; MGC105261; MTE-II; Rbach

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACOT7 (acyl-CoA thioesterase 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ACOT7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ACOT7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Acot7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acot7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acot7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acot7	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	167,969,284 - 168,062,033 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	167,968,895 - 168,062,033 (+)	Ensembl				GRCr8
mRatBN7.2	5	162,686,562 - 162,779,309 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,684,645 - 162,779,309 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	165,389,812 - 165,482,377 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,211,405 - 167,303,979 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	167,173,603 - 167,266,173 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	169,357,582 - 169,450,215 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,357,517 - 169,450,219 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	160,918,240 - 161,010,763 (+)	NCBI		Celera
RGSC_v3.1	5	169,419,590 - 169,512,094 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime (ISO)

acetamide (EXP)

aconitine (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bisphenol F (ISO)

bortezomib (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

clofibrate (EXP)

clofibric acid (EXP)

clozapine (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (EXP,ISO)

Dibutyl phosphate (ISO)

dichlorine (EXP)

diethylstilbestrol (ISO)

endosulfan (EXP)

Enterolactone (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

fenofibrate (EXP)

fenthion (ISO)

finasteride (EXP)

folic acid (ISO)

fulvestrant (ISO)

furfural (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

GW 4064 (ISO)

hydrogen peroxide (ISO)

indometacin (EXP,ISO)

ivermectin (ISO)

lead diacetate (ISO)

leflunomide (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Muraglitazar (EXP)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

okadaic acid (ISO)

oleic acid (ISO)

ozone (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (EXP,ISO)

progesterone (ISO)

quinoline (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

Tesaglitazar (EXP)

thapsigargin (ISO)

theophylline (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

troglitazone (EXP)

tunicamycin (ISO)

valproic acid (ISO)

zinc atom (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acyl-CoA metabolic process (IBA)

coenzyme A biosynthetic process (IEA,ISO)

fatty acid catabolic process (IBA,ISO)

fatty acid metabolic process (IEA)

lipid metabolic process (IEA)

long-chain fatty-acyl-CoA catabolic process (IEA,ISO)

medium-chain fatty acid biosynthetic process (IEA,ISO)

medium-chain fatty-acyl-CoA catabolic process (IEA,ISO)

palmitic acid biosynthetic process (IEA,ISO)

Cellular Component

cell body (ISO)

cytoplasm (IBA,IEA,ISO)

cytosol (IBA,IEA,ISO)

mitochondrial matrix (ISO)

neuron projection (ISO)

Molecular Function

carboxylic ester hydrolase activity (IEA)

fatty acyl-CoA hydrolase activity (IDA,IEA)

fatty-acyl-CoA binding (IEA,ISO)

hydrolase activity (IEA)

identical protein binding (ISO)

long-chain fatty acyl-CoA binding (IEA,ISO)

long-chain fatty acyl-CoA hydrolase activity (IBA,IEA,ISO)

protein binding (ISO)

protein homodimerization activity (IEA,ISO)

thiolester hydrolase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

unsaturated fatty acid biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular cloning and expression of cDNA encoding rat brain cytosolic acyl-coenzyme A thioester hydrolase.	Broustas CG, etal., J Biol Chem 1996 May 3;271(18):10470-6.
2.	Peroxisome proliferator-induced acyl-CoA thioesterase from rat liver cytosol: molecular cloning and functional expression in Chinese hamster ovary cells.	Engberg ST, etal., Biochem J 1997 Apr 15;323 ( Pt 2):525-31.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Molecular cloning and expression of cDNAs encoding rat brain and liver cytosolic long-chain acyl-CoA hydrolases.	Yamada J, etal., Biochem Biophys Res Commun 1997 Mar 6;232(1):198-203.

Additional References at PubMed

PMID:7906114	PMID:10578051	PMID:11755680	PMID:11834298	PMID:12435388	PMID:12477932	PMID:15489334	PMID:16103133	PMID:17563367	PMID:18324622	PMID:19056867

Genomics

Comparative Map Data

Acot7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	167,969,284 - 168,062,033 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	167,968,895 - 168,062,033 (+)	Ensembl				GRCr8
mRatBN7.2	5	162,686,562 - 162,779,309 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,684,645 - 162,779,309 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	165,389,812 - 165,482,377 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,211,405 - 167,303,979 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	167,173,603 - 167,266,173 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	169,357,582 - 169,450,215 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,357,517 - 169,450,219 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	160,918,240 - 161,010,763 (+)	NCBI		Celera
RGSC_v3.1	5	169,419,590 - 169,512,094 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

ACOT7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	6,264,272 - 6,393,767 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	6,264,268 - 6,393,767 (-)	Ensembl			hg38	GRCh38
GRCh37	1	6,324,332 - 6,453,827 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	6,246,919 - 6,376,413 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	5,438,842 - 5,568,337 (-)	NCBI		Celera
Cytogenetic Map	1	p36.31	NCBI
HuRef	1	5,472,303 - 5,601,612 (-)	NCBI		HuRef
CHM1_1	1	6,312,939 - 6,442,400 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	5,789,916 - 5,919,409 (-)	NCBI		T2T-CHM13v2.0

Acot7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	152,258,872 - 152,356,312 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	152,262,591 - 152,356,312 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	152,178,100 - 152,271,855 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	152,178,134 - 152,271,855 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	151,552,209 - 151,645,964 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	151,021,934 - 151,115,647 (+)	NCBI		MGSCv36	mm8
Celera	4	154,464,405 - 154,558,717 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	82.93	NCBI

Acot7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	6,188,102 - 6,259,110 (+)	Ensembl
ChiLan1.0	NW_004955486	6,188,102 - 6,258,230 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACOT7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	221,834,121 - 221,959,854 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	220,475,344 - 220,601,209 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	5,030,488 - 5,154,800 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	6,287,177 - 6,402,767 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

ACOT7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	60,153,616 - 60,239,254 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	60,153,616 - 60,239,239 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	60,163,440 - 60,265,782 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	60,369,414 - 60,471,489 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	60,369,414 - 60,471,855 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	60,368,684 - 60,471,165 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	60,235,482 - 60,337,604 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	60,637,013 - 60,739,144 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Acot7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	30,626,783 - 30,710,871 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936623	1,112,338 - 1,191,064 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936623	1,112,021 - 1,191,190 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACOT7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	67,152,429 - 67,254,103 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	67,152,428 - 67,254,097 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	62,103,745 - 62,205,894 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACOT7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	125,345,636 - 125,474,650 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	125,345,670 - 125,474,690 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	29,408,450 - 29,580,377 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acot7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	5,065,995 - 5,142,558 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624818	5,048,410 - 5,142,135 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Acot7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	8,471,544 - 8,562,634 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	346
Count of miRNA genes:	126
Interacting mature miRNAs:	142
Transcripts:	ENSRNOT00000000079, ENSRNOT00000014213
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149642129	171146538	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	160111176	171146538	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	156289283	171137955	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	160071170	172129029	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat

Markers in Region

RH129039

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	162,779,058 - 162,779,275 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	169,449,965 - 169,450,181	NCBI	Rnor6.0
Rnor_5.0	5	173,003,304 - 173,003,520	UniSTS	Rnor5.0
RGSC_v3.4	5	169,501,657 - 169,501,873	UniSTS	RGSC3.4
Celera	5	161,010,513 - 161,010,729	UniSTS
RH 3.4 Map	5	1139.3	UniSTS
Cytogenetic Map	5	q36	UniSTS

AW557066

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	162,778,914 - 162,779,065 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	169,449,821 - 169,449,971	NCBI	Rnor6.0
Rnor_5.0	5	173,003,160 - 173,003,310	UniSTS	Rnor5.0
RGSC_v3.4	5	169,501,513 - 169,501,663	UniSTS	RGSC3.4
Celera	5	161,010,369 - 161,010,519	UniSTS
Cytogenetic Map	5	q36	UniSTS

D1S2335E

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	162,768,913 - 162,769,030 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	169,439,820 - 169,439,936	NCBI	Rnor6.0
Rnor_5.0	5	172,993,159 - 172,993,275	UniSTS	Rnor5.0
RGSC_v3.4	5	169,491,512 - 169,491,628	UniSTS	RGSC3.4
Celera	5	161,000,368 - 161,000,484	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001146061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429474	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_013214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC135674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK469690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D88891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY317682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U49694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y09332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000000079 ⟹ ENSRNOP00000000079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	167,990,542 - 168,062,033 (+)	Ensembl
mRatBN7.2 Ensembl	5	162,707,818 - 162,779,309 (+)	Ensembl
Rnor_6.0 Ensembl	5	169,357,517 - 169,450,219 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000014213 ⟹ ENSRNOP00000014213

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	167,976,051 - 168,062,032 (+)	Ensembl
mRatBN7.2 Ensembl	5	162,693,306 - 162,779,309 (+)	Ensembl
Rnor_6.0 Ensembl	5	169,364,306 - 169,450,214 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118204 ⟹ ENSRNOP00000089356

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	167,968,895 - 168,062,032 (+)	Ensembl
mRatBN7.2 Ensembl	5	162,684,645 - 162,779,309 (+)	Ensembl

RefSeq Acc Id:

NM_001146061 ⟹ NP_001139533

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	167,976,126 - 168,062,033 (+)	NCBI
mRatBN7.2	5	162,693,400 - 162,779,309 (+)	NCBI
Rnor_6.0	5	169,364,306 - 169,450,215 (+)	NCBI
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	RGD
Celera	5	160,924,964 - 161,010,763 (+)	NCBI

Sequence:

show sequence

CAGCTGCTAAGCTTGGTGCTGTGAGGGAAGAGAAAGGCTTTGTCCCATTCCTAGAATGAAGCTG
CTTGCTAGGACTCTGTACCTCTGGGAGGTGGGGAGACAGGTAGCCTCTTGGAGCCTGACGTCTG
GCCAGGAGTGTTTGGTGCTCAGGGAAACATGGTGGGCTTCGATGAGGGCTGTCAGAACCAGAGC
AGTTCATCACAAGCCTGGACATTGCATCGCCATGGGAAGGATCATGCGTCCGGATGATGCCAAC
GTGGCCGGCAATGTTCACGGAGGGACCATTCTAAAGATGATCGAGGAGGCTGGGGTCATCATCA
GCACCCGGCACTGTAACAGCCAGAATGGGGAGCGCTGTGTGGCTGCCCTGGCCCGGGTGGAGCG
CACTGACTTCCTGTCGCCCATGTGCATCGGTGAGGTGGCTCACGTCAGCGCAGAGATCACCTAT
ACTTCCAAGCACTCTGTGGAGGTCCAGGTCCACGTGTTGTCGGAGAACATCCTCACAGGTACCA
AAAAGCTGACCAATAAGGCCACCTTGTGGTATGTGCCCCTGTCATTGAAGAATGTGGACAAGGT
CCTTGAGGTGCCTCCTATTGTGTATTTACGGCAGGAACAGGAGGAGGAGGGTCGGAAACGCTAT
GAAGCCCAGAAGCTAGAACGCATGGAGACCAAGTGGAGGAACGGAGACATTGTCCAGCCCATCC
TGAACCCAGAGCCGAACACAGTGAGCTACAGCCAGTCCAGCCTGATCCACCTGGTGGGGCCCTC
AGACTGCACTCTTCATGGCTTCGTGCACGGAGGTGTCACCATGAAGCTCATGGATGAGGTGGCC
GGGATTGTGGCTGCGCGCCACTGCAAGACCAATATAGTGACTGCCTCTGTGGATGCTATTAATT
TCCATGACAAGATCCGGAAAGGCTGTGTCATCACCATCTCTGGACGCATGACCTTCACAAGCAA
TAAGTCTATGGAAATTGAGGTCCTGGTGGACGCTGACCCTGTGGTGGACAACTCACAGAAGCGC
TACCGGGCTGCCAGTGCCTTCTTCACCTACGTGTCCCTGAATCAGGAGGGCAAGCCGCTGCCTG
TGCCTCAGCTTGTGCCGGAGACGGAGGACGAGAAGAAGCGTTTTGAAGAAGGCAAAGGCCGCTA
TCTGCAGATGAAGGCGAAGCGACAGGGCCATACAGAGCCTCAGCCCTAGATGTCTTCCTCCCTC
CCATCCTGTCCCGTCCTGGGTCAGCACAGTTGTGGCAGTAGTCCTGTGTGCAGTCACTTAGAAG
TCGCCCCCTTGGCCAAACCCCGATTTCCTTTGAGAGCTGGTGTTGTGAAGTACCGTGTGGCAGT
GTTACCTGTGGCCTGTTCCCAAAACCTGTGCACCAAAGCTTTATTTATATCCCTCCAGTCCCTG
CTCCCATGTTGTCCCAAAGGCCATCGTGGACACCAGAGCACACTGACTGGCCTGGAGAAGCCAG
CACCACTAATAAAGCTGCTGTCTGGCTGGAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_013214 ⟹ NP_037346

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	167,969,402 - 168,062,033 (+)	NCBI
mRatBN7.2	5	162,686,676 - 162,779,309 (+)	NCBI
Rnor_6.0	5	169,357,582 - 169,450,215 (+)	NCBI
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	RGD
Celera	5	160,918,240 - 161,010,763 (+)	RGD

Sequence:

show sequence

CTCCTCTTTTATGGCGCCTCCCAGGCTCATTCATTCGGCGCCGGGCCTGCTGGACACCTGTTCT
CAGATCCCGCCGCCGCCGTCGCCGCCGCCGCCCGCCGTCGCAGCCAAGATGTCCGGTCCCACCA
CCGACACGCCGGCCGCCATCCAGATCTGCCGGATCATGCGTCCGGATGATGCCAACGTGGCCGG
CAATGTTCACGGAGGGACCATTCTAAAGATGATCGAGGAGGCTGGGGTCATCATCAGCACCCGG
CACTGTAACAGCCAGAATGGGGAGCGCTGTGTGGCTGCCCTGGCCCGGGTGGAGCGCACTGACT
TCCTGTCGCCCATGTGCATCGGTGAGGTGGCTCACGTCAGCGCAGAGATCACCTATACTTCCAA
GCACTCTGTGGAGGTCCAGGTCCACGTGTTGTCGGAGAACATCCTCACAGGTACCAAAAAGCTG
ACCAATAAGGCCACCTTGTGGTATGTGCCCCTGTCATTGAAGAATGTGGACAAGGTCCTTGAGG
TGCCTCCTATTGTGTATTTACGGCAGGAACAGGAGGAGGAGGGTCGGAAACGCTATGAAGCCCA
GAAGCTAGAACGCATGGAGACCAAGTGGAGGAACGGAGACATTGTCCAGCCCATCCTGAACCCA
GAGCCGAACACAGTGAGCTACAGCCAGTCCAGCCTGATCCACCTGGTGGGGCCCTCAGACTGCA
CTCTTCATGGCTTCGTGCACGGAGGTGTCACCATGAAGCTCATGGATGAGGTGGCCGGGATTGT
GGCTGCGCGCCACTGCAAGACCAATATAGTGACTGCCTCTGTGGATGCTATTAATTTCCATGAC
AAGATCCGGAAAGGCTGTGTCATCACCATCTCTGGACGCATGACCTTCACAAGCAATAAGTCTA
TGGAAATTGAGGTCCTGGTGGACGCTGACCCTGTGGTGGACAACTCACAGAAGCGCTACCGGGC
TGCCAGTGCCTTCTTCACCTACGTGTCCCTGAATCAGGAGGGCAAGCCGCTGCCTGTGCCTCAG
CTTGTGCCGGAGACGGAGGACGAGAAGAAGCGTTTTGAAGAAGGCAAAGGCCGCTATCTGCAGA
TGAAGGCGAAGCGACAGGGCCATACAGAGCCTCAGCCCTAGATGTCTTCCTCCCTCCCATCCTG
TCCCGTCCTGGGTCAGCACAGTTGTGGCAGTAGTCCTGTGTGCAGTCACTTAGAAGTCGCCCCC
TTGGCCAAACCCCGATTTCCTTTGAGAGCTGGTGTTGTGAAGTACCGTGTGGCAGTGTTACCTG
TGGCCTGTTCCCAAAACCTGTGCACCAAAGCTTTATTTATATCCCTCCAGTCCCTGCTCCCATG
TTGTCCCAAAGGCCATCGTGGACACCAGAGCACACTGACTGGCCTGGAGAAGCCAGCACCACTA
ATAAAGCTGCTGTCTGGCTGGAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239448 ⟹ XP_006239510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	167,990,626 - 168,062,033 (+)	NCBI
mRatBN7.2	5	162,707,899 - 162,779,309 (+)	NCBI
Rnor_6.0	5	169,378,805 - 169,450,215 (+)	NCBI
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI

Sequence:

show sequence

TGAGTTAGGAACTGGGCGGAGCTGGGGCTTCCCTGAGTGGGAGAAGTGTTGAGACCTGCTTTGG
TACCTGAGTGGTCAGATCTGTGGTGGTCTGACCTTGGGTGGTCTGACCTTTGGCTTGGGGTCCT
GGGATGCTTTGGTGTCCTTTCCTCTGACTTGAAGGATCATGCGTCCGGATGATGCCAACGTGGC
CGGCAATGTTCACGGAGGGACCATTCTAAAGATGATCGAGGAGGCTGGGGTCATCATCAGCACC
CGGCACTGTAACAGCCAGAATGGGGAGCGCTGTGTGGCTGCCCTGGCCCGGGTGGAGCGCACTG
ACTTCCTGTCGCCCATGTGCATCGGTGAGGTGGCTCACGTCAGCGCAGAGATCACCTATACTTC
CAAGCACTCTGTGGAGGTCCAGGTCCACGTGTTGTCGGAGAACATCCTCACAGGTACCAAAAAG
CTGACCAATAAGGCCACCTTGTGGTATGTGCCCCTGTCATTGAAGAATGTGGACAAGGTCCTTG
AGGTGCCTCCTATTGTGTATTTACGGCAGGAACAGGAGGAGGAGGGTCGGAAACGCTATGAAGC
CCAGAAGCTAGAACGCATGGAGACCAAGTGGAGGAACGGAGACATTGTCCAGCCCATCCTGAAC
CCAGAGCCGAACACAGTGAGCTACAGCCAGTCCAGCCTGATCCACCTGGTGGGGCCCTCAGACT
GCACTCTTCATGGCTTCGTGCACGGAGGTGTCACCATGAAGCTCATGGATGAGGTGGCCGGGAT
TGTGGCTGCGCGCCACTGCAAGACCAATATAGTGACTGCCTCTGTGGATGCTATTAATTTCCAT
GACAAGATCCGGAAAGGCTGTGTCATCACCATCTCTGGACGCATGACCTTCACAAGCAATAAGT
CTATGGAAATTGAGGTCCTGGTGGACGCTGACCCTGTGGTGGACAACTCACAGAAGCGCTACCG
GGCTGCCAGTGCCTTCTTCACCTACGTGTCCCTGAATCAGGAGGGCAAGCCGCTGCCTGTGCCT
CAGCTTGTGCCGGAGACGGAGGACGAGAAGAAGCGTTTTGAAGAAGGCAAAGGCCGCTATCTGC
AGATGAAGGCGAAGCGACAGGGCCATACAGAGCCTCAGCCCTAGATGTCTTCCTCCCTCCCATC
CTGTCCCGTCCTGGGTCAGCACAGTTGTGGCAGTAGTCCTGTGTGCAGTCACTTAGAAGTCGCC
CCCTTGGCCAAACCCCGATTTCCTTTGAGAGCTGGTGTTGTGAAGTACCGTGTGGCAGTGTTAC
CTGTGGCCTGTTCCCAAAACCTGTGCACCAAAGCTTTATTTATATCCCTCCAGTCCCTGCTCCC
ATGTTGTCCCAAAGGCCATCGTGGACACCAGAGCACACTGACTGGCCTGGAGAAGCCAGCACCA
CTAATAAAGCTGCTGTCTGGCTGGA

hide sequence

RefSeq Acc Id:

XM_039109339 ⟹ XP_038965267

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	167,976,110 - 168,062,033 (+)	NCBI
mRatBN7.2	5	162,693,418 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_039109340 ⟹ XP_038965268

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	167,969,284 - 168,062,033 (+)	NCBI
mRatBN7.2	5	162,686,562 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_039109343 ⟹ XP_038965271

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,016,111 - 168,062,033 (+)	NCBI
mRatBN7.2	5	162,733,399 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_063287218 ⟹ XP_063143288

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	167,976,097 - 168,051,772 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001139533	(Get FASTA)	NCBI Sequence Viewer
	NP_001416401	(Get FASTA)	NCBI Sequence Viewer
	NP_001416402	(Get FASTA)	NCBI Sequence Viewer
	NP_001416403	(Get FASTA)	NCBI Sequence Viewer
	NP_001416404	(Get FASTA)	NCBI Sequence Viewer
	NP_001416405	(Get FASTA)	NCBI Sequence Viewer
	NP_037346	(Get FASTA)	NCBI Sequence Viewer
	XP_006239510	(Get FASTA)	NCBI Sequence Viewer
	XP_038965267	(Get FASTA)	NCBI Sequence Viewer
	XP_038965268	(Get FASTA)	NCBI Sequence Viewer
	XP_038965271	(Get FASTA)	NCBI Sequence Viewer
	XP_063143288	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC53202	(Get FASTA)	NCBI Sequence Viewer
	AAH87716	(Get FASTA)	NCBI Sequence Viewer
	BAA19627	(Get FASTA)	NCBI Sequence Viewer
	CAA70512	(Get FASTA)	NCBI Sequence Viewer
	EDL81226	(Get FASTA)	NCBI Sequence Viewer
	EDL81227	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000000079
	ENSRNOP00000014213
	ENSRNOP00000089356
GenBank Protein	Q64559	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_037346 ⟸ NM_013214
- Peptide Label:	isoform 2
- UniProtKB:	A6IUH5 (UniProtKB/TrEMBL), A0A8I6ACH7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPPRLIHSAPGLLDTCSQIPPPPSPPPPAVAAKMSGPTTDTPAAIQICRIMRPDDANVAGNVH GGTILKMIEEAGVIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSV EVQVHVLSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLE RMETKWRNGDIVQPILNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAAR HCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASA FFTYVSLNQEGKPLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQP hide sequence

RefSeq Acc Id:	NP_001139533 ⟸ NM_001146061
- Peptide Label:	isoform 1
- UniProtKB:	O08652 (UniProtKB/Swiss-Prot), O09041 (UniProtKB/Swiss-Prot), Q64559 (UniProtKB/Swiss-Prot), A6IUH6 (UniProtKB/TrEMBL), A0A8L2Q6N9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLLARTLYLWEVGRQVASWSLTSGQECLVLRETWWASMRAVRTRAVHHKPGHCIAMGRIMRPD DANVAGNVHGGTILKMIEEAGVIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAE ITYTSKHSVEVQVHVLSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGR KRYEAQKLERMETKWRNGDIVQPILNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMD EVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNS QKRYRAASAFFTYVSLNQEGKPLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQP hide sequence

RefSeq Acc Id:

XP_006239510 ⟸ XM_006239448

- Peptide Label:

isoform X3

- Sequence:

show sequence

MRPDDANVAGNVHGGTILKMIEEAGVIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAH
VSAEITYTSKHSVEVQVHVLSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQE
EEGRKRYEAQKLERMETKWRNGDIVQPILNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTM
KLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPV
VDNSQKRYRAASAFFTYVSLNQEGKPLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQ
P

hide sequence

Ensembl Acc Id:

ENSRNOP00000000079 ⟸ ENSRNOT00000000079

Ensembl Acc Id:

ENSRNOP00000014213 ⟸ ENSRNOT00000014213

RefSeq Acc Id:	XP_038965268 ⟸ XM_039109340
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038965267 ⟸ XM_039109339
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038965271 ⟸ XM_039109343
- Peptide Label:	isoform X5

Ensembl Acc Id:

ENSRNOP00000089356 ⟸ ENSRNOT00000118204

RefSeq Acc Id:	XP_063143288 ⟸ XM_063287218
- Peptide Label:	isoform X4

Protein Domains

HotDog ACOT-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64559-F1-model_v2	AlphaFold	Q64559	1-381	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694303

Promoter ID:

EPDNEW_R4824

Type:

initiation region

Name:

Acot7_1

Description:

acyl-CoA thioesterase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4825

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	169,357,614 - 169,357,674	EPDNEW

RGD ID:

13694301

Promoter ID:

EPDNEW_R4825

Type:

initiation region

Name:

Acot7_2

Description:

acyl-CoA thioesterase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4824

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	169,364,301 - 169,364,361	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628856	AgrOrtholog
BioCyc Gene	G2FUF-39018	BioCyc
BioCyc Pathway	PWY-5148 [acyl-CoA hydrolysis]	BioCyc
	PWY-5972 [stearate biosynthesis I (animals)]	BioCyc
	PWY-5996 [oleate biosynthesis II (animals and fungi)]	BioCyc
	PWY-8042 [acylceramide biosynthesis]	BioCyc
	PWY3O-1801 [palmitoleate biosynthesis IV (fungi and animals)]	BioCyc
BioCyc Pathway Image	PWY-5148	BioCyc
	PWY-5972	BioCyc
	PWY-5996	BioCyc
	PWY-8042	BioCyc
	PWY3O-1801	BioCyc
Ensembl Genes	ENSRNOG00000010580	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000000079	ENTREZGENE
	ENSRNOT00000014213	ENTREZGENE
	ENSRNOT00000118204	ENTREZGENE
Gene3D-CATH	Hotdog Thioesterase	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7316866	IMAGE-MGC_LOAD
InterPro	Cytosol_ACT	UniProtKB/Swiss-Prot
	HOTDOG_ACOT	UniProtKB/Swiss-Prot
	HotDog_dom_sf	UniProtKB/Swiss-Prot
	Thioestr_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:26759	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105261	IMAGE-MGC_LOAD
NCBI Gene	26759	ENTREZGENE
PANTHER	CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE	UniProtKB/Swiss-Prot
	PTHR11049	UniProtKB/Swiss-Prot
Pfam	4HBT	UniProtKB/Swiss-Prot
PhenoGen	Acot7	PhenoGen
PROSITE	HOTDOG_ACOT	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000010580	RatGTEx
Superfamily-SCOP	SSF54637	UniProtKB/Swiss-Prot
UniProt	A0A8I6ACH7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2Q6N9	ENTREZGENE, UniProtKB/TrEMBL
	A6IUH5	ENTREZGENE, UniProtKB/TrEMBL
	A6IUH6	ENTREZGENE, UniProtKB/TrEMBL
	BACH_RAT	UniProtKB/Swiss-Prot
	F8WG67	ENTREZGENE, UniProtKB/TrEMBL
	O08652	ENTREZGENE
	O09041	ENTREZGENE
	Q64559	ENTREZGENE
UniProt Secondary	O08652	UniProtKB/Swiss-Prot
	O09041	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Acot7	acyl-CoA thioesterase 7	Bach	brain acyl-CoA hydrolase	Symbol and Name updated	1299863	APPROVED
2005-01-20	Bach	brain acyl-CoA hydrolase			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Bach	brain acyl-CoA hydrolase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Annotations - KEGG (archival)

BioCyc Pathways