Acot7 (acyl-CoA thioesterase 7) - Rat Genome Database

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Gene: Acot7 (acyl-CoA thioesterase 7) Chinchilla lanigera
Analyze
Symbol: Acot7
Name: acyl-CoA thioesterase 7
RGD ID: 8821238
Description: ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); fatty-acyl-CoA binding (ortholog); identical protein binding (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); fatty acid catabolic process (ortholog); long-chain fatty-acyl-CoA catabolic process (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytosolic acyl coenzyme A thioester hydrolase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,188,102 - 6,259,110 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554866,188,102 - 6,258,230 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Acot7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,188,102 - 6,259,110 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554866,188,102 - 6,258,230 (+)NCBIChiLan1.0ChiLan1.0
ACOT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,264,272 - 6,393,767 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,264,269 - 6,393,767 (-)EnsemblGRCh38hg38GRCh38
GRCh3716,324,332 - 6,453,827 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,246,919 - 6,376,413 (-)NCBINCBI36Build 36hg18NCBI36
Celera15,438,842 - 5,568,337 (-)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,472,303 - 5,601,612 (-)NCBIHuRef
CHM1_116,312,939 - 6,442,400 (-)NCBICHM1_1
T2T-CHM13v2.015,789,916 - 5,919,409 (-)NCBIT2T-CHM13v2.0
Acot7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,258,872 - 152,356,312 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,262,591 - 152,356,312 (+)EnsemblGRCm39 Ensembl
GRCm384152,178,100 - 152,271,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,178,134 - 152,271,855 (+)EnsemblGRCm38mm10GRCm38
MGSCv374151,552,209 - 151,645,964 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364151,021,934 - 151,115,647 (+)NCBIMGSCv36mm8
Celera4154,464,405 - 154,558,717 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map482.93NCBI
Acot7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,969,284 - 168,062,033 (+)NCBIGRCr8
mRatBN7.25162,686,562 - 162,779,309 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,684,645 - 162,779,309 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,389,812 - 165,482,377 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,211,405 - 167,303,979 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,173,603 - 167,266,173 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,357,582 - 169,450,215 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,357,517 - 169,450,219 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05172,912,096 - 173,003,554 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,409,306 - 169,501,907 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,419,590 - 169,512,094 (+)NCBI
Celera5160,918,240 - 161,010,763 (+)NCBICelera
Cytogenetic Map5q36NCBI
ACOT7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,834,121 - 221,959,854 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,475,344 - 220,601,209 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015,030,488 - 5,154,800 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,287,177 - 6,402,767 (-)NCBIpanpan1.1PanPan1.1panPan2
ACOT7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,153,616 - 60,239,254 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,153,616 - 60,239,239 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha560,163,440 - 60,265,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0560,369,414 - 60,471,489 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,369,414 - 60,471,855 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,368,684 - 60,471,165 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,235,482 - 60,337,604 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,637,013 - 60,739,144 (-)NCBIUU_Cfam_GSD_1.0
Acot7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,626,783 - 30,710,871 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,112,338 - 1,191,064 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,112,021 - 1,191,190 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACOT7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,152,429 - 67,254,103 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1667,152,428 - 67,254,097 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,103,745 - 62,205,894 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACOT7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,345,636 - 125,474,650 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20125,345,670 - 125,474,690 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605429,408,450 - 29,580,377 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acot7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248185,065,995 - 5,142,558 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248185,048,410 - 5,142,135 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000018098   ⟹   ENSCLAP00000017920
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554866,188,102 - 6,259,110 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000018099   ⟹   ENSCLAP00000017921
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554866,188,635 - 6,257,935 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000018100   ⟹   ENSCLAP00000017922
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554866,197,627 - 6,259,110 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000018101   ⟹   ENSCLAP00000017923
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554866,203,239 - 6,259,110 (+)Ensembl
RefSeq Acc Id: XM_005404096   ⟹   XP_005404153
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554866,188,102 - 6,258,230 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005404097   ⟹   XP_005404154
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554866,197,627 - 6,258,230 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504310   ⟹   XP_013359764
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554866,203,752 - 6,258,230 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005404153   ⟸   XM_005404096
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YRH7 (UniProtKB/TrEMBL),   A0A8C2YRG8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404154   ⟸   XM_005404097
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VMU8 (UniProtKB/TrEMBL),   A0A8C2VV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013359764   ⟸   XM_013504310
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VV27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017922   ⟸   ENSCLAT00000018100
RefSeq Acc Id: ENSCLAP00000017923   ⟸   ENSCLAT00000018101
RefSeq Acc Id: ENSCLAP00000017920   ⟸   ENSCLAT00000018098
RefSeq Acc Id: ENSCLAP00000017921   ⟸   ENSCLAT00000018099
Protein Domains
HotDog ACOT-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012294 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018098 ENTREZGENE
  ENSCLAT00000018098.1 UniProtKB/TrEMBL
  ENSCLAT00000018099.1 UniProtKB/TrEMBL
  ENSCLAT00000018100 ENTREZGENE
  ENSCLAT00000018100.1 UniProtKB/TrEMBL
  ENSCLAT00000018101 ENTREZGENE
  ENSCLAT00000018101.1 UniProtKB/TrEMBL
Gene3D-CATH Hotdog Thioesterase UniProtKB/TrEMBL
InterPro Cytosol_ACT UniProtKB/TrEMBL
  HOTDOG_ACOT UniProtKB/TrEMBL
  HotDog_dom_sf UniProtKB/TrEMBL
  Thioestr_dom UniProtKB/TrEMBL
NCBI Gene Acot7 ENTREZGENE
PANTHER CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE UniProtKB/TrEMBL
  PTHR11049 UniProtKB/TrEMBL
Pfam 4HBT UniProtKB/TrEMBL
PROSITE HOTDOG_ACOT UniProtKB/TrEMBL
Superfamily-SCOP SSF54637 UniProtKB/TrEMBL
UniProt A0A8C2VMU8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VV27 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YRG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YRH7 ENTREZGENE, UniProtKB/TrEMBL