Kcnq5 (potassium voltage-gated channel subfamily Q member 5) - Rat Genome Database

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Pathways
Gene: Kcnq5 (potassium voltage-gated channel subfamily Q member 5) Rattus norvegicus
Analyze
Symbol: Kcnq5
Name: potassium voltage-gated channel subfamily Q member 5
RGD ID: 628848
Description: Enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential and voltage-gated potassium channel activity. Involved in potassium ion transport. Is active in calyx of Held and presynaptic membrane. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 46. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Kcnq5l; LOC689123; potassium channel, voltage-gated KQT-like subfamily Q, member 5; potassium voltage-gated channel subfamily KQT member 5; potassium voltage-gated channel, KQT-like subfamily, member 5; potassium voltage-gated channel, subfamily Q, member 5; potassium voltage-gated channel, subfamily Q, member 5-like; similar to Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel alpha subunit KvLQT5) (KQT-like 5)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8931,326,595 - 31,892,399 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl931,329,497 - 31,891,304 (-)EnsemblGRCr8
mRatBN7.2923,830,185 - 24,395,984 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx932,326,367 - 32,887,878 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0937,447,044 - 38,008,537 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0935,762,286 - 36,323,828 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0927,565,869 - 28,141,114 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl927,562,959 - 27,761,733 (-)Ensemblrn6Rnor6.0
Rnor_5.0926,413,162 - 26,986,457 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4920,181,402 - 20,767,644 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera921,408,169 - 21,967,095 (-)NCBICelera
RGSC_v3.1920,293,226 - 20,293,677 (-)NCBI
Cytogenetic Map9q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. The potassium channel KCNQ5/Kv7.5 is localized in synaptic endings of auditory brainstem nuclei of the rat. Caminos E, etal., J Comp Neurol. 2007 Dec 1;505(4):363-78. doi: 10.1002/cne.21497.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KCNQ5 channels control resting properties and release probability of a synapse. Huang H and Trussell LO, Nat Neurosci. 2011 Jun 12;14(7):840-7. doi: 10.1038/nn.2830.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Molecular correlates of the M-current in cultured rat hippocampal neurons. Shah MM, etal., J Physiol 2002 Oct 1;544(Pt 1):29-37.
9. The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels. Yus-Najera E, etal., J Biol Chem 2002 Aug 9;277(32):28545-53.
Additional References at PubMed
PMID:8889548   PMID:10787416   PMID:11159685   PMID:15632090   PMID:15963599   PMID:17071736   PMID:17322297   PMID:18048450   PMID:18331828   PMID:18786918   PMID:19246091   PMID:20151361  
PMID:20624791   PMID:21750731   PMID:24297175   PMID:24446351   PMID:24558103   PMID:24855057   PMID:25421809   PMID:25616413   PMID:28189443   PMID:28669405   PMID:31570602   PMID:32739272  
PMID:33667331  


Genomics

Comparative Map Data
Kcnq5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8931,326,595 - 31,892,399 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl931,329,497 - 31,891,304 (-)EnsemblGRCr8
mRatBN7.2923,830,185 - 24,395,984 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx932,326,367 - 32,887,878 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0937,447,044 - 38,008,537 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0935,762,286 - 36,323,828 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0927,565,869 - 28,141,114 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl927,562,959 - 27,761,733 (-)Ensemblrn6Rnor6.0
Rnor_5.0926,413,162 - 26,986,457 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4920,181,402 - 20,767,644 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera921,408,169 - 21,967,095 (-)NCBICelera
RGSC_v3.1920,293,226 - 20,293,677 (-)NCBI
Cytogenetic Map9q13NCBI
KCNQ5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38672,622,064 - 73,198,853 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl672,621,792 - 73,198,853 (+)Ensemblhg38GRCh38
GRCh37673,331,792 - 73,908,576 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36673,388,556 - 73,962,301 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34673,388,555 - 73,962,301NCBI
Celera673,724,971 - 74,301,723 (+)NCBICelera
Cytogenetic Map6q13NCBI
HuRef670,530,024 - 71,107,055 (+)NCBIHuRef
CHM1_1673,498,230 - 74,075,278 (+)NCBICHM1_1
T2T-CHM13v2.0673,798,716 - 74,375,478 (+)NCBIT2T-CHM13v2.0
Kcnq5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39121,468,623 - 22,032,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl121,468,627 - 22,032,166 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38121,398,399 - 21,962,650 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl121,398,403 - 21,961,942 (-)Ensemblmm10GRCm38
MGSCv37121,388,484 - 21,952,023 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36121,387,314 - 21,946,732 (-)NCBIMGSCv36mm8
Celera121,280,293 - 21,849,214 (-)NCBICelera
Cytogenetic Map1A4NCBI
cM Map16.67NCBI
Kcnq5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554887,406,635 - 7,927,532 (+)Ensembl
ChiLan1.0NW_0049554887,406,633 - 7,928,526 (+)NCBIChiLan1.0ChiLan1.0
KCNQ5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2592,601,093 - 93,177,834 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1690,526,540 - 91,103,615 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0670,448,161 - 71,025,173 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1673,741,208 - 74,315,757 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl673,742,191 - 74,312,344 (+)EnsemblpanPan2panpan1.1
KCNQ5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11234,872,514 - 35,364,794 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1234,872,581 - 35,362,349 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1234,737,803 - 35,233,429 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01235,413,242 - 35,916,493 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1235,413,242 - 35,913,762 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11234,948,630 - 35,457,677 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01234,986,659 - 35,479,229 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01235,098,552 - 35,603,898 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kcnq5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494670,125,573 - 70,658,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366184,283,349 - 4,812,036 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366184,283,240 - 4,815,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNQ5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl152,435,235 - 52,939,823 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1152,435,332 - 52,939,705 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2158,773,511 - 59,277,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNQ5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,932,962 - 2,495,926 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl171,930,803 - 2,128,570 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660587,855,745 - 8,424,719 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnq5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248196,889,658 - 7,365,537 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248196,886,328 - 7,365,537 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Kcnq5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1498,752,531 - 99,302,666 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kcnq5
5255 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:162
Count of miRNA genes:70
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000018552, ENSRNOT00000040034
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9141763315Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)92103143049025574Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat

Markers in Region
D9Rat180  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8931,613,165 - 31,613,400 (+)Marker Load Pipeline
mRatBN7.2924,116,762 - 24,116,997 (+)MAPPERmRatBN7.2
mRatBN7.2924,116,078 - 24,116,997 (+)MAPPERmRatBN7.2
Rnor_6.0927,858,560 - 27,859,505NCBIRnor6.0
Rnor_6.0927,859,271 - 27,859,505NCBIRnor6.0
Rnor_5.0926,705,889 - 26,706,123UniSTSRnor5.0
Rnor_5.0926,705,178 - 26,706,123UniSTSRnor5.0
RGSC_v3.4920,474,389 - 20,474,623UniSTSRGSC3.4
RGSC_v3.4920,474,388 - 20,474,623RGDRGSC3.4
Celera921,690,031 - 21,690,263UniSTS
RGSC_v3.1920,475,802 - 20,476,037RGD
SHRSP x BN Map920.1098UniSTS
SHRSP x BN Map920.1098RGD
Cytogenetic Map9q13UniSTS
D9Got31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,297,837 - 24,298,072 (+)MAPPERmRatBN7.2
Rnor_6.0928,045,520 - 28,045,754NCBIRnor6.0
Rnor_5.0926,890,948 - 26,891,182UniSTSRnor5.0
Celera921,870,523 - 21,870,757UniSTS
RH 3.4 Map9224.5UniSTS
RH 3.4 Map9224.5RGD
RH 2.0 Map9187.0RGD
Cytogenetic Map9q13UniSTS
RH138014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,075,461 - 24,075,696 (+)MAPPERmRatBN7.2
Rnor_6.0927,817,440 - 27,817,674NCBIRnor6.0
Rnor_5.0926,665,206 - 26,665,440UniSTSRnor5.0
Celera921,649,469 - 21,649,703UniSTS
RH 3.4 Map9229.29UniSTS
Cytogenetic Map9q13UniSTS
RH131959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,387,590 - 24,387,771 (+)MAPPERmRatBN7.2
Rnor_6.0928,133,826 - 28,134,006NCBIRnor6.0
Rnor_5.0926,979,169 - 26,979,349UniSTSRnor5.0
RGSC_v3.4920,760,376 - 20,760,556UniSTSRGSC3.4
Celera921,959,807 - 21,959,987UniSTS
RH 3.4 Map9237.0UniSTS
Cytogenetic Map9q13UniSTS
BE106461  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8931,410,920 - 31,411,070 (+)Marker Load Pipeline
mRatBN7.2923,914,507 - 23,914,657 (+)MAPPERmRatBN7.2
Rnor_6.0927,647,434 - 27,647,583NCBIRnor6.0
Rnor_5.0926,494,727 - 26,494,876UniSTSRnor5.0
RGSC_v3.4920,262,523 - 20,262,672UniSTSRGSC3.4
Celera921,489,344 - 21,489,493UniSTS
RH 3.4 Map9229.5UniSTS
Cytogenetic Map9q13UniSTS
RH141099  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,833,570 - 23,833,750 (+)MAPPERmRatBN7.2
Rnor_6.0927,566,353 - 27,566,532NCBIRnor6.0
Rnor_5.0926,413,646 - 26,413,825UniSTSRnor5.0
RGSC_v3.4920,181,586 - 20,181,765UniSTSRGSC3.4
Celera921,408,653 - 21,408,832UniSTS
RH 3.4 Map9229.6UniSTS
Cytogenetic Map9q13UniSTS
AU049631  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,970,175 - 23,970,321 (+)MAPPERmRatBN7.2
mRatBN7.2923,970,175 - 23,970,479 (+)MAPPERmRatBN7.2
Rnor_6.0927,703,085 - 27,703,228NCBIRnor6.0
Rnor_6.0927,703,085 - 27,703,411NCBIRnor6.0
Rnor_5.0926,550,378 - 26,550,704UniSTSRnor5.0
Rnor_5.0926,550,378 - 26,550,521UniSTSRnor5.0
RGSC_v3.4920,318,182 - 20,318,327UniSTSRGSC3.4
Celera921,544,941 - 21,545,086UniSTS
Cytogenetic Map9q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 66 146 86 85 54 83 54 6 332 182 11 122 78 92 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000018552   ⟹   ENSRNOP00000018552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl931,329,497 - 31,891,304 (-)Ensembl
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
Rnor_6.0 Ensembl927,565,869 - 27,761,365 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097073   ⟹   ENSRNOP00000079928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl931,329,497 - 31,891,304 (-)Ensembl
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098049   ⟹   ENSRNOP00000097404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl931,329,497 - 31,891,304 (-)Ensembl
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106244   ⟹   ENSRNOP00000084442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl931,329,497 - 31,891,304 (-)Ensembl
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
RefSeq Acc Id: NM_001134643   ⟹   NP_001128115
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,329,497 - 31,891,281 (-)NCBI
mRatBN7.2923,833,087 - 24,394,880 (-)NCBI
Rnor_6.0927,565,869 - 28,141,114 (-)NCBI
Rnor_5.0926,413,162 - 26,986,457 (-)NCBI
Celera921,408,169 - 21,967,095 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083094   ⟹   XP_038939022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,326,595 - 31,892,376 (-)NCBI
mRatBN7.2923,830,185 - 24,395,887 (-)NCBI
RefSeq Acc Id: XM_039083095   ⟹   XP_038939023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,326,595 - 31,892,377 (-)NCBI
mRatBN7.2923,830,185 - 24,395,887 (-)NCBI
RefSeq Acc Id: XM_039083097   ⟹   XP_038939025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,404,772 - 31,892,399 (-)NCBI
mRatBN7.2923,906,602 - 24,395,984 (-)NCBI
RefSeq Acc Id: NP_001128115   ⟸   NM_001134643
- UniProtKB: F1LY25 (UniProtKB/TrEMBL),   A6JJ99 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018552   ⟸   ENSRNOT00000018552
RefSeq Acc Id: XP_038939023   ⟸   XM_039083095
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNI9 (UniProtKB/TrEMBL),   A6JJ99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939022   ⟸   XM_039083094
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXW9 (UniProtKB/TrEMBL),   A6JJ99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939025   ⟸   XM_039083097
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000084442   ⟸   ENSRNOT00000106244
Ensembl Acc Id: ENSRNOP00000079928   ⟸   ENSRNOT00000097073
Ensembl Acc Id: ENSRNOP00000097404   ⟸   ENSRNOT00000098049
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LY25-F1-model_v2 AlphaFold F1LY25 1-821 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628848 AgrOrtholog
BioCyc Gene G2FUF-27994 BioCyc
Ensembl Genes ENSRNOG00000013781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018552 ENTREZGENE
  ENSRNOT00000018552.10 UniProtKB/TrEMBL
  ENSRNOT00000097073.2 UniProtKB/TrEMBL
  ENSRNOT00000098049.2 UniProtKB/TrEMBL
  ENSRNOT00000106244 ENTREZGENE
  ENSRNOT00000106244.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  6.10.140.1910 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ_C UniProtKB/TrEMBL
KEGG Report rno:259273 UniProtKB/TrEMBL
NCBI Gene 259273 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 UniProtKB/TrEMBL
  POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  KCNQ_channel UniProtKB/TrEMBL
PhenoGen Kcnq5 PhenoGen
PRINTS KCHANNEL UniProtKB/TrEMBL
  KCNQCHANNEL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013781 RatGTEx
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8I5ZNI9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AWB8_RAT UniProtKB/TrEMBL
  A6JJ99 ENTREZGENE, UniProtKB/TrEMBL
  F1LY25 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3W7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Kcnq5  potassium voltage-gated channel subfamily Q member 5  Kcnq5  potassium channel, voltage-gated KQT-like subfamily Q, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-26 Kcnq5  potassium channel, voltage-gated KQT-like subfamily Q, member 5  Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-18 Kcnq5l  potassium voltage-gated channel, subfamily Q, member 5-like  Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Data merged from RGD:1596181 737654 APPROVED
2012-07-18 Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Kcnq5l  potassium voltage-gated channel, subfamily Q, member 5-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Kcnq5  potassium voltage-gated channel, subfamily Q, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Kcnq5  potassium voltage-gated channel, subfamily Q, member 5  LOC689123  similar to Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel alpha subunit KvLQT5) (KQT-like 5)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Kcnq5l  potassium voltage-gated channel, subfamily Q, member 5-like  Kcnq5  potassium voltage-gated channel, subfamily Q, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689123  similar to Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel alpha subunit KvLQT5) (KQT-like 5)      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Kcnq5  potassium voltage-gated channel, subfamily Q, member 5    potassium voltage-gated channel, KQT-like subfamily, member 5  Name updated 1299863 APPROVED
2003-02-27 Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5      Symbol and Name status set to provisional 70820 PROVISIONAL