Copb2 (coat protein complex I subunit beta 2) - Rat Genome Database

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Gene: Copb2 (coat protein complex I subunit beta 2) Rattus norvegicus
Analyze
Symbol: Copb2
Name: coat protein complex I subunit beta 2 (Ensembl:COPI coat complex subunit beta 2)
RGD ID: 628746
Description: Enables protein kinase C binding activity. Predicted to be involved in Golgi vesicle transport and intracellular protein transport. Located in Golgi membrane. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 19. Orthologous to human COPB2 (COPI coat complex subunit beta 2); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta prime COP; beta'-coat protein; beta'-COP; coatomer protein complex subunit beta 2; coatomer protein complex, subunit beta 2 (beta prime); coatomer subunit beta'; COPI coat complex subunit beta 2; MGC93460; p102; Rack2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,040,687 - 108,062,810 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8108,040,693 - 108,064,550 (+)EnsemblGRCr8
mRatBN7.2899,161,324 - 99,183,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,161,350 - 99,185,197 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8104,829,033 - 104,851,106 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,028,302 - 103,050,376 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,870,802 - 100,892,876 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,582,339 - 106,603,763 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,024,920 - 106,047,170 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera898,569,531 - 98,591,507 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
caffeine  (ISO)
captan  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
methamphetamine  (EXP)
methidathion  (ISO)
methimazole  (EXP)
miconazole  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
picoxystrobin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
Salinomycin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sulfadimethoxine  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
trichloroethene  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation. Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2. Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic. Burman JL, etal., J Biol Chem. 2008 Aug 15;283(33):22774-86. doi: 10.1074/jbc.M801869200. Epub 2008 Jun 13.
3. The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon. Csukai M, etal., J Biol Chem 1997 Nov 14;272(46):29200-6.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. Loh E, etal., J Cell Sci. 2005 Mar 15;118(Pt 6):1209-22. Epub 2005 Feb 22.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8335000   PMID:8947846   PMID:12477932   PMID:14729954   PMID:15358183   PMID:16854843   PMID:18434597   PMID:18504258   PMID:19631211   PMID:20724702   PMID:20801885   PMID:22871113  
PMID:23716698   PMID:24625528   PMID:25002582  


Genomics

Comparative Map Data
Copb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,040,687 - 108,062,810 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8108,040,693 - 108,064,550 (+)EnsemblGRCr8
mRatBN7.2899,161,324 - 99,183,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,161,350 - 99,185,197 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8104,829,033 - 104,851,106 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,028,302 - 103,050,376 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,870,802 - 100,892,876 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,582,339 - 106,603,763 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,024,920 - 106,047,170 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera898,569,531 - 98,591,507 (+)NCBICelera
Cytogenetic Map8q31NCBI
COPB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,357,406 - 139,389,680 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,353,942 - 139,389,736 (-)Ensemblhg38GRCh38
GRCh373139,076,248 - 139,108,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,559,123 - 140,591,151 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343140,559,132 - 140,591,159NCBI
Celera3137,499,384 - 137,531,480 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,451,880 - 136,483,977 (-)NCBIHuRef
CHM1_13139,039,998 - 139,072,089 (-)NCBICHM1_1
T2T-CHM13v2.03142,104,959 - 142,137,239 (-)NCBIT2T-CHM13v2.0
Copb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,445,784 - 98,470,428 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,445,774 - 98,470,435 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38998,563,731 - 98,588,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,563,721 - 98,588,382 (+)Ensemblmm10GRCm38
MGSCv37998,464,150 - 98,488,794 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36998,373,083 - 98,397,727 (+)NCBIMGSCv36mm8
Celera998,109,355 - 98,134,004 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.4NCBI
Copb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555086,201,989 - 6,231,845 (+)Ensembl
ChiLan1.0NW_0049555086,201,989 - 6,231,840 (+)NCBIChiLan1.0ChiLan1.0
COPB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,271,754 - 137,303,751 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,272,816 - 137,308,481 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,394,480 - 136,426,544 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13143,994,312 - 144,026,277 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3143,994,312 - 144,020,117 (-)EnsemblpanPan2panpan1.1
COPB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,536,520 - 35,604,708 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,536,615 - 35,566,569 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2335,524,048 - 35,592,583 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02336,075,179 - 36,143,336 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,074,618 - 36,143,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,755,206 - 35,823,768 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02335,828,808 - 35,896,988 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,070,552 - 36,139,285 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Copb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,727,380 - 74,753,469 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,467,169 - 1,493,258 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,467,169 - 1,493,218 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COPB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,218,989 - 80,264,762 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11380,220,460 - 80,264,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21387,894,952 - 87,931,027 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COPB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11551,165,275 - 51,197,971 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604124,142,863 - 24,183,665 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Copb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473015,908,551 - 15,936,856 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473015,908,551 - 15,936,886 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Copb2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1889,937,156 - 89,959,290 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Copb2
96 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:22
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000075603
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)897492344116428905Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH129978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2899,183,240 - 99,183,443 (+)MAPPERmRatBN7.2
Rnor_6.08106,603,550 - 106,603,754NCBIRnor6.0
Celera898,591,295 - 98,591,498UniSTS
RH 3.4 Map81051.7UniSTS
AU048956  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2899,163,041 - 99,163,284 (+)MAPPERmRatBN7.2
Rnor_6.08106,584,071 - 106,584,313NCBIRnor6.0
Celera898,571,234 - 98,571,480UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 52 67 138 95 11 51 36 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000080434   ⟹   ENSRNOP00000071536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8108,045,022 - 108,060,888 (+)Ensembl
mRatBN7.2 Ensembl899,165,660 - 99,181,530 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101351   ⟹   ENSRNOP00000094254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8108,040,693 - 108,064,550 (+)Ensembl
mRatBN7.2 Ensembl899,161,350 - 99,185,197 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115328   ⟹   ENSRNOP00000088501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8108,044,883 - 108,064,550 (+)Ensembl
mRatBN7.2 Ensembl899,165,521 - 99,185,197 (+)Ensembl
RefSeq Acc Id: NM_021765   ⟹   NP_068533
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,040,687 - 108,062,810 (+)NCBI
mRatBN7.2899,161,324 - 99,183,452 (+)NCBI
Rnor_6.08106,582,339 - 106,603,763 (+)NCBI
Rnor_5.08106,024,920 - 106,047,170 (+)NCBI
Celera898,569,531 - 98,591,507 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_068533 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB38315 (Get FASTA)   NCBI Sequence Viewer  
  AAB88018 (Get FASTA)   NCBI Sequence Viewer  
  AAH88397 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000094254
GenBank Protein O35142 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068533   ⟸   NM_021765
- UniProtKB: A0A8I6GKN2 (UniProtKB/TrEMBL),   A6I2B6 (UniProtKB/TrEMBL),   Q5M7X1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071536   ⟸   ENSRNOT00000080434
Ensembl Acc Id: ENSRNOP00000094254   ⟸   ENSRNOT00000101351
Ensembl Acc Id: ENSRNOP00000088501   ⟸   ENSRNOT00000115328
Protein Domains
COPA/B second beta-propeller   COPA/B TPR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0P9-F1-model_v2 AlphaFold A0A0G2K0P9 1-733 view protein structure
AF-O35142-F1-model_v2 AlphaFold O35142 1-905 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628746 AgrOrtholog
BioCyc Gene G2FUF-29416 BioCyc
Ensembl Genes ENSRNOG00000060723 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000101351 ENTREZGENE
Gene3D-CATH 1.25.40.470 UniProtKB/Swiss-Prot
  2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7190660 IMAGE-MGC_LOAD
InterPro Coatomer_complex_subunit UniProtKB/Swiss-Prot
  Coatomer_WD-assoc_reg UniProtKB/Swiss-Prot
  COPB2 UniProtKB/Swiss-Prot
  G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  TPR_COPA_B UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:60384 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93460 IMAGE-MGC_LOAD
NCBI Gene 60384 ENTREZGENE
PANTHER COATOMER UniProtKB/Swiss-Prot
  COATOMER SUBUNIT BETA UniProtKB/Swiss-Prot
Pfam Coatomer_WDAD UniProtKB/Swiss-Prot
  TPR_COPA_B UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Copb2 PhenoGen
PIRSF Coatomer_beta'_subunit UniProtKB/Swiss-Prot
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060723 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A0G2K0P9_RAT UniProtKB/TrEMBL
  A0A8I6AA32_RAT UniProtKB/TrEMBL
  A0A8I6GKN2 ENTREZGENE, UniProtKB/TrEMBL
  A6I2B6 ENTREZGENE, UniProtKB/TrEMBL
  COPB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5M7X1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Copb2  coat protein complex I subunit beta 2  Copb2  COPI coat complex subunit beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-11-11 Copb2  COPI coat complex subunit beta 2  Copb2  coatomer protein complex subunit beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-13 Copb2  coatomer protein complex subunit beta 2  Copb2  coatomer protein complex, subunit beta 2 (beta prime)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Copb2  coatomer protein complex, subunit beta 2 (beta prime)    beta prime COP  Name updated 1299863 APPROVED
2003-02-27 Copb2  beta prime COP      Symbol and Name status set to provisional 70820 PROVISIONAL