Stc2 (stanniocalcin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Stc2 (stanniocalcin 2) Rattus norvegicus
Analyze
Symbol: Stc2
Name: stanniocalcin 2
RGD ID: 621777
Description: Predicted to enable enzyme binding activity; heme binding activity; and protein homodimerization activity. Involved in several processes, including decidualization; embryo implantation; and response to vitamin D. Acts upstream of or within intracellular calcium ion homeostasis. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Predicted to be active in extracellular space. Orthologous to human STC2 (stanniocalcin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: stanniocalcin-2; STC-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81016,755,508 - 16,765,275 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1016,755,267 - 16,767,447 (+)EnsemblGRCr8
mRatBN7.21016,251,046 - 16,260,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1016,250,853 - 16,262,973 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1020,999,993 - 21,009,760 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01020,488,943 - 20,498,710 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01015,978,545 - 15,988,328 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01016,542,909 - 16,552,675 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1016,542,882 - 16,553,295 (+)Ensemblrn6Rnor6.0
Rnor_5.01016,432,189 - 16,441,955 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41016,514,603 - 16,524,369 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1015,912,872 - 15,922,638 (+)NCBICelera
RGSC_v3.11016,515,651 - 16,525,418 (+)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(E)-thiamethoxam  (ISO)
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Bisphenol Z  (ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
Didecyldimethylammonium  (ISO)
diethylstilbestrol  (EXP,ISO)
dimethylarsinic acid  (EXP)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
diphenylcyclopropenone  (ISO)
diquat  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP,ISO)
enniatin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (EXP)
GW 4064  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
iron dichloride  (ISO)
ketoconazole  (ISO)
L-methionine  (ISO)
lamivudine  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
miconazole  (ISO)
mitomycin C  (ISO)
Moniliformin  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N(4)-hydroxycytidine  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
nicotine  (ISO)
okadaic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
picene  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
prothioconazole  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
tetrachloroethene  (ISO)
thapsigargin  (ISO)
thiamethoxam  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triacsin C  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vorinostat  (ISO)
XL147  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Regulation by 1alpha,25-dihydroxyvitamin D(3) of expression of stanniocalcin messages in the rat kidney and ovary. Honda S, etal., FEBS Lett 1999 Oct 1;459(1):119-22.
4. Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties. Ito D, etal., Mol Cell Biol. 2004 Nov;24(21):9456-69.
5. Differential gene signatures in rat mammary tumors induced by DMBA and those induced by fractionated gamma radiation. Lee HJ, etal., Radiat Res. 2008 Nov;170(5):579-90.
6. Identification of a stanniocalcin paralog, stanniocalcin-2, in fish and the paracrine actions of stanniocalcin-2 in the mammalian ovary. Luo CW, etal., Endocrinology. 2005 Jan;146(1):469-76. Epub 2004 Oct 14.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm. Wang T, etal., Front Immunol. 2022 May 27;13:843408. doi: 10.3389/fimmu.2022.843408. eCollection 2022.
14. Expression and regulation of stanniocalcin 1 and 2 in rat uterus during embryo implantation and decidualization. Xiao LJ, etal., Reproduction. 2006 Jun;131(6):1137-49.
15. Stanniocalcin 2 is a negative modulator of store-operated calcium entry. Zeiger W, etal., Mol Cell Biol. 2011 Sep;31(18):3710-22. doi: 10.1128/MCB.05140-11. Epub 2011 Jul 11.
Additional References at PubMed
PMID:9753616   PMID:16502470   PMID:18258678   PMID:22285620   PMID:22503972  


Genomics

Comparative Map Data
Stc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81016,755,508 - 16,765,275 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1016,755,267 - 16,767,447 (+)EnsemblGRCr8
mRatBN7.21016,251,046 - 16,260,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1016,250,853 - 16,262,973 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1020,999,993 - 21,009,760 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01020,488,943 - 20,498,710 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01015,978,545 - 15,988,328 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01016,542,909 - 16,552,675 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1016,542,882 - 16,553,295 (+)Ensemblrn6Rnor6.0
Rnor_5.01016,432,189 - 16,441,955 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41016,514,603 - 16,524,369 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1015,912,872 - 15,922,638 (+)NCBICelera
RGSC_v3.11016,515,651 - 16,525,418 (+)NCBI
Cytogenetic Map10q12NCBI
STC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385173,314,723 - 173,328,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5173,314,723 - 173,328,447 (-)Ensemblhg38GRCh38
GRCh375172,741,726 - 172,755,417 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365172,674,332 - 172,689,112 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345172,660,711 - 172,687,936NCBI
Celera5168,774,827 - 168,789,607 (-)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5167,836,956 - 167,851,740 (-)NCBIHuRef
CHM1_15172,174,113 - 172,188,892 (-)NCBICHM1_1
T2T-CHM13v2.05173,854,781 - 173,868,472 (-)NCBIT2T-CHM13v2.0
Stc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391131,309,441 - 31,320,061 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1131,307,307 - 31,320,074 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381131,359,441 - 31,370,061 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,357,307 - 31,370,074 (-)Ensemblmm10GRCm38
MGSCv371131,259,441 - 31,270,061 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361131,259,441 - 31,270,061 (-)NCBIMGSCv36mm8
Celera1133,778,331 - 33,788,980 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.4NCBI
Stc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540825,934,932 - 25,949,399 (-)Ensembl
ChiLan1.0NW_00495540825,937,174 - 25,950,221 (-)NCBIChiLan1.0ChiLan1.0
STC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24168,451,252 - 168,463,400 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15166,588,413 - 166,603,171 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05168,668,851 - 168,681,274 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15175,575,412 - 175,587,832 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5175,575,419 - 175,587,832 (-)EnsemblpanPan2panpan1.1
STC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1439,151,951 - 39,165,514 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl439,152,503 - 39,162,343 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha439,097,951 - 39,109,709 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0439,523,070 - 39,537,223 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl439,524,206 - 39,534,846 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1439,341,084 - 39,355,222 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0439,529,915 - 39,543,843 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0440,038,732 - 40,052,874 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Stc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721393,596,596 - 93,607,949 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366092,319,111 - 2,332,988 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366092,319,546 - 2,331,049 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1650,989,433 - 51,004,481 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11650,989,676 - 51,001,412 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21655,330,021 - 55,341,757 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12375,475,020 - 75,489,727 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2375,475,022 - 75,488,678 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660343,118,074 - 3,132,787 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473316,773,644 - 16,785,214 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473316,773,422 - 16,787,475 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Stc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v194,525,493 - 4,535,955 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Stc2
52 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:78
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000028146
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101576223019737486Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 12 66 154 90 89 58 29 58 6 275 128 11 131 69 91 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000028146   ⟹   ENSRNOP00000028146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1016,755,267 - 16,767,447 (+)Ensembl
mRatBN7.2 Ensembl1016,250,853 - 16,262,973 (+)Ensembl
Rnor_6.0 Ensembl1016,542,882 - 16,553,295 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103133   ⟹   ENSRNOP00000093400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1016,251,052 - 16,262,702 (+)Ensembl
RefSeq Acc Id: NM_022230   ⟹   NP_071566
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81016,755,508 - 16,765,275 (+)NCBI
mRatBN7.21016,251,046 - 16,260,815 (+)NCBI
Rnor_6.01016,542,909 - 16,552,675 (+)NCBI
Rnor_5.01016,432,189 - 16,441,955 (+)NCBI
RGSC_v3.41016,514,603 - 16,524,369 (+)RGD
Celera1015,912,872 - 15,922,638 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_071566 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA85251 (Get FASTA)   NCBI Sequence Viewer  
  EDM04038 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028146
  ENSRNOP00000028146.1
GenBank Protein Q9R0K8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071566   ⟸   NM_022230
- Peptide Label: precursor
- UniProtKB: Q9R0K8 (UniProtKB/Swiss-Prot),   A6HDD3 (UniProtKB/TrEMBL),   A0A8I6AKX3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028146   ⟸   ENSRNOT00000028146
Ensembl Acc Id: ENSRNOP00000093400   ⟸   ENSRNOT00000103133

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R0K8-F1-model_v2 AlphaFold Q9R0K8 1-296 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697086
Promoter ID:EPDNEW_R7610
Type:initiation region
Name:Stc2_1
Description:stanniocalcin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01016,542,915 - 16,542,975EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621777 AgrOrtholog
BioCyc Gene G2FUF-25652 BioCyc
Ensembl Genes ENSRNOG00000020729 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028146 ENTREZGENE
  ENSRNOT00000028146.4 UniProtKB/Swiss-Prot
InterPro Stanniocalcin UniProtKB/Swiss-Prot
KEGG Report rno:63878 UniProtKB/Swiss-Prot
NCBI Gene 63878 ENTREZGENE
PANTHER PTHR11245 UniProtKB/Swiss-Prot
  STANNIOCALCIN-2 UniProtKB/Swiss-Prot
Pfam Stanniocalcin UniProtKB/Swiss-Prot
PhenoGen Stc2 PhenoGen
RatGTEx ENSRNOG00000020729 RatGTEx
UniProt A0A8I6AKX3 ENTREZGENE
  A6HDD3 ENTREZGENE, UniProtKB/TrEMBL
  Q9R0K8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Stc2  stanniocalcin 2    stanniocalcin-2  Name updated 1299863 APPROVED
2002-08-07 Stc2  stanniocalcin-2      Symbol and Name status set to provisional 70820 PROVISIONAL