Advanced Search (OLGA)

Gene: Khdrbs2 (KH RNA binding domain containing, signal transduction associated 2) Rattus norvegicus

Analyze

Symbol:

Khdrbs2

Name:

KH RNA binding domain containing, signal transduction associated 2

RGD ID:

621738

Description:

Predicted to enable RNA binding activity and protein domain specific binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to human KHDRBS2 (KH RNA binding domain containing, signal transduction associated 2); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

KH domain containing, RNA binding, signal transduction associated 2; KH domain-containing, RNA-binding, signal transduction-associated protein 2; rSLM-1; Sam68-like mammalian protein 1; SLM-1; Slm1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	41,943,029 - 42,449,687 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	41,943,050 - 42,412,905 (+)	Ensembl				GRCr8
mRatBN7.2	9	34,447,023 - 34,953,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	34,447,056 - 34,915,530 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	42,939,773 - 43,410,674 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	48,075,177 - 48,543,663 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	46,357,022 - 46,825,573 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	39,501,431 - 40,008,707 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	39,539,530 - 40,008,680 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	39,171,658 - 39,679,421 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	30,918,047 - 31,404,074 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	32,245,972 - 32,715,211 (+)	NCBI		Celera
RGSC_v3.1	9	30,919,460 - 31,405,485 (+)	NCBI
Cytogenetic Map	9	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

melanoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

chlorpyrifos (EXP)

ethanol (ISO)

fonofos (ISO)

genistein (EXP,ISO)

levetiracetam (EXP)

linsidomine (EXP)

maneb (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

parathion (ISO)

phenytoin (EXP)

rotenone (ISO)

terbufos (ISO)

testosterone (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

mRNA processing (IEA)

regulation of alternative mRNA splicing, via spliceosome (IBA)

regulation of mRNA splicing, via spliceosome (IEA,ISO)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

mRNA binding (IBA)

nucleic acid binding (IEA)

poly(A) binding (IBA,IEA,ISO)

poly(U) RNA binding (IEA,ISO)

protein binding (IPI,ISO)

RNA binding (IEA)

SH2 domain binding (IEA,ISO)

SH3 domain binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis.	Di Fruscio M, etal., Proc Natl Acad Sci U S A 1999 Mar 16;96(6):2710-5.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA.	Heinrich B, etal., J Biol Chem. 2009 May 22;284(21):14303-15. Epub 2009 Mar 12.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1.	Stoss O, etal., Mol Cell Neurosci 2004 Sep;27(1):8-21.

Additional References at PubMed

PMID:21516116	PMID:22196734	PMID:25416956

Genomics

Comparative Map Data

Khdrbs2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	41,943,029 - 42,449,687 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	41,943,050 - 42,412,905 (+)	Ensembl				GRCr8
mRatBN7.2	9	34,447,023 - 34,953,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	34,447,056 - 34,915,530 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	42,939,773 - 43,410,674 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	48,075,177 - 48,543,663 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	46,357,022 - 46,825,573 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	39,501,431 - 40,008,707 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	39,539,530 - 40,008,680 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	39,171,658 - 39,679,421 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	30,918,047 - 31,404,074 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	32,245,972 - 32,715,211 (+)	NCBI		Celera
RGSC_v3.1	9	30,919,460 - 31,405,485 (+)	NCBI
Cytogenetic Map	9	q21	NCBI

KHDRBS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	61,542,670 - 62,286,225 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	61,630,234 - 62,286,225 (-)	Ensembl			hg38	GRCh38
GRCh37	6	62,252,575 - 62,996,130 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	62,447,824 - 63,054,091 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	62,447,823 - 63,054,091	NCBI
Celera	6	60,547,513 - 61,153,711 (-)	NCBI		Celera
Cytogenetic Map	6	q11.1	NCBI
HuRef	6	59,556,167 - 60,162,759 (-)	NCBI		HuRef
CHM1_1	6	62,556,127 - 63,162,398 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	62,687,495 - 63,431,119 (-)	NCBI		T2T-CHM13v2.0

Khdrbs2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	32,211,683 - 32,744,305 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	32,211,795 - 32,697,649 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	32,172,602 - 32,705,224 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	32,172,714 - 32,658,568 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	32,229,651 - 32,714,583 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	32,117,352 - 32,602,284 (+)	NCBI		MGSCv36	mm8
Celera	1	31,966,556 - 32,446,126 (+)	NCBI		Celera
Cytogenetic Map	1	B	NCBI
cM Map	1	11.86	NCBI

Khdrbs2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955502	1,509,237 - 1,943,297 (+)	Ensembl
ChiLan1.0	NW_004955502	1,486,799 - 1,944,298 (+)	NCBI	ChiLan1.0	ChiLan1.0

KHDRBS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	76,335,683 - 77,131,007 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	70,997,531 - 71,791,120 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	59,161,367 - 59,954,702 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	64,550,407 - 65,228,125 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	64,624,694 - 65,227,850 (-)	Ensembl			panPan2	panpan1.1

KHDRBS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	25,544,069 - 26,142,284 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	25,585,694 - 26,142,337 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	25,455,103 - 26,052,270 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	26,081,733 - 26,679,733 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	26,105,536 - 26,679,783 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	25,626,421 - 26,181,127 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	25,664,086 - 26,261,662 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	25,795,120 - 26,364,939 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Khdrbs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	60,940,318 - 61,490,805 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	2,469,349 - 3,000,993 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	2,469,396 - 3,001,997 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KHDRBS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	27,390,918 - 27,895,597 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	27,348,614 - 27,895,572 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	31,958,286 - 32,322,254 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KHDRBS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	12,522,386 - 13,150,784 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	12,522,531 - 12,898,201 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666058	18,836,350 - 19,478,329 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Khdrbs2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624753	20,209,485 - 20,757,679 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624753	20,174,101 - 20,757,402 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Khdrbs2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	108,539,225 - 108,988,719 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Khdrbs2
4123 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	262
Count of miRNA genes:	174
Interacting mature miRNAs:	201
Transcripts:	ENSRNOT00000016578
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5346479	50346479	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	40029925	85029925	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	8750492	53750492	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	31250432	68875676	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	29567664	74567664	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	29567664	83835942	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	41720295	86720295	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	496645	45496645	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	6214995	51214995	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	8750492	53750492	Rat
7207805	Bmd88	Bone mineral density QTL 88	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	9	31250432	65651574	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5346479	50416711	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	496645	45496645	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	21031430	49025574	Rat
1581517	Bp284	Blood pressure QTL 284			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	39220186	84220186	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	496645	45496645	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	40029925	85029925	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	6214995	51214995	Rat
1598823	Memor16	Memory QTL 16	1.9		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	31456061	57460683	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	34960590	79960590	Rat

Markers in Region

AU047600

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	42,255,665 - 42,255,831 (+)	Marker Load Pipeline
mRatBN7.2	9	34,759,659 - 34,759,825 (-)	MAPPER	mRatBN7.2
Rnor_6.0	9	39,696,010 - 39,696,175	NCBI	Rnor6.0
Rnor_5.0	9	39,366,544 - 39,366,709	UniSTS	Rnor5.0
RGSC_v3.4	9	31,246,578 - 31,246,743	UniSTS	RGSC3.4
Celera	9	32,559,074 - 32,559,239	UniSTS
Cytogenetic Map	9	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	6	42	153	37	26	13	9	13	3	168	70	4	138	70	88	13	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001839640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005488844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005488845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005488846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF305618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000016578 ⟹ ENSRNOP00000016579

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	41,943,050 - 42,411,839 (+)	Ensembl
mRatBN7.2 Ensembl	9	34,447,056 - 34,915,530 (+)	Ensembl
Rnor_6.0 Ensembl	9	39,539,530 - 40,008,680 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107830 ⟹ ENSRNOP00000095124

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	41,943,050 - 42,066,980 (+)	Ensembl
mRatBN7.2 Ensembl	9	34,447,056 - 34,570,970 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113927 ⟹ ENSRNOP00000076472

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	41,943,050 - 42,014,432 (+)	Ensembl
mRatBN7.2 Ensembl	9	34,447,056 - 34,518,418 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000146709 ⟹ ENSRNOP00000101510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	41,943,050 - 42,412,905 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154861 ⟹ ENSRNOP00000100781

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	41,943,050 - 42,411,913 (+)	Ensembl

RefSeq Acc Id:

NM_133318 ⟹ NP_579852

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,070 - 42,411,545 (+)	NCBI
mRatBN7.2	9	34,447,056 - 34,915,540 (+)	NCBI
Rnor_6.0	9	39,539,520 - 40,008,680 (-)	NCBI
Rnor_5.0	9	39,171,658 - 39,679,421 (-)	NCBI
RGSC_v3.4	9	30,918,047 - 31,404,074 (+)	RGD
Celera	9	32,245,972 - 32,715,211 (+)	RGD

Sequence:

show sequence

AGGCGGGAGAGGCAGGTACCAGCGCGGTCTGCGCAGCCCGAGGCGCTAGAGCTGCGCTCACCGC
AGGAAGGACGGTTCCTGGGGGAACCAGGGACCGAGGCGTCCGAGCAGGCGGGATTTGCGCCTGG
CCGGCCACGGTCCGAAGTCCGCGCTATGGGAGAAGAGAAATACTTGCCTGAGCTGATGGCAGAG
AAGGATAGCCTTGATCCATCTTTTGTGCACGCGTCGCGCCTTCTGGCGGAAGAAATTGAGAAAT
TCCAAGGCTCGGATGGAAGAAAAGAAGATGAGGAAAAGAAGTATCTCGATGTCATCAGCAACAA
AAACATAAAGCTCTCGGAAAGGGTATTGATCCCCGTGAAACAGTATCCAAAGTTCAATTTTGTG
GGGAAATTGCTTGGACCAAGAGGAAACTCCTTGAAGAGGCTACAAGAAGAAACGGGTGCTAAAA
TGTCTATCCTGGGCAAAGGATCGATGCGTGACAAGGCAAAGGAAGAAGAGCTGAGGAAGAGTGG
GGAGGCCAAGTATGCCCACCTGAGTGACGAACTGCACGTATTAATTGAAGTGTTTGCTCCACCC
GGGGAAGCTTACTCACGGATGAGTCATGCTTTGGAAGAGATTAAAAAATTCCTGGTTCCTGACT
ACAATGATGAAATTCGTCAAGAGCAACTCCGGGAGTTGTCTTACTTGAATGGCTCAGAAGAGTC
TGGCCGGGGCCGAGGTATTAGAGGCAGAGGGATCAGAATAACTCCCACAGCTCCTTCAAGGGGC
CGTGGGGGTGCTGTTCCACCACCACCACCACCTGGACGAGGTGTTCTTACCCCTCGGGGAACCA
CTGTGACCCGCGGAGCTCTCCCAGTACCCCCAGTAGCAAGAGGTGTCCCAACACCTCGAGCCCG
GGGAACAGCAGCGGTCCCAGGATACAGAGCGCCCCCACCTCCAGCTCCTGAGGCTTATGAAGAG
TATGGGTACGATGATGGCTATGGGGGTGAATATGATGACCAGACCTATGAGGCTTATGATAATA
GCTACGTGACCCCGACACAAAGTGTGCCTGAATACTATGACTATGGTCATGGAGTAAATGAGGA
TGCCTATGACAGCTACGCACCAGAAGAATGGACCACAACCCGCTCCAGCCTGAAGGCACCACCA
CCAAGGTCAGCCAGAGGGGGATACAGGGAACACCCCTATGGTAGATATTGAAGGTCCTCTTCAC
CTGGTGACCTCCTCAAAGACAATTCATAGCCTGTGCTCTTCACATTAAACAGCAACAAGACAAG
TAATAGTCTTTTTTGTTTGTTTTGTTTTTTCTATCCTAGGGGGATAACTGCTCATAATTACTCC
CACCCTATTCTTGTATTCTCTTAATACTGGTTAACGTTGACATGGACATTAGTATTATTTTATA
AAACAGACTGGAAAAAAAAGAGACTGGCAAGCATAGTTTATAAACCATTCTGTAGGTTGATATT
CTCTTGATTGTTTTTTTTTTTAATTGTTGTGTGTAAACCGCCAACCCCTTCCCTTTCCTTTTCG
GTTTCCTTTCTCCTTTTTCTTTTGTAGAAAAAAAAAGAGCATGAACCTGTTAGATTTTGAGTCT
CAACCAACTAGCCGAACCTTTGTTTAGGGTTGTTAAAAGACTGTAATATGATTTTGAACTAGCT
GATAACACAGTTGTAGATAAGATGTTTTAACCTGTCTTTTAATATCTGTTAGTCAGATGGAGAT
GTTCAATATTAAGTTGTAAATTTAATTTTTAAATGCTGTTTTAATGGGGTGGAAAACAAGCAGC
TACTGTATGTATGTAGCTAACTGAATTTGTTCAGTGTTTTAACCTGTATTTGTTAAAAAAAGAA
AAAAGAAAAAAACACACATGAAGTTCCATGTGTAAGCTTCTCTAAATAGGAACCACAATTTGTC
AAATATGTTTGCCATAATTTGTCAATAAAGCTGAAGGCTTTTGTAAAAACTAAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039082989 ⟹ XP_038938917

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,029 - 42,411,818 (+)	NCBI
mRatBN7.2	9	34,447,024 - 34,915,815 (+)	NCBI

RefSeq Acc Id:

XR_005488844

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,029 - 42,449,560 (+)	NCBI
mRatBN7.2	9	34,447,024 - 34,953,684 (+)	NCBI

RefSeq Acc Id:

XR_005488845

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,029 - 42,449,687 (+)	NCBI
mRatBN7.2	9	34,447,023 - 34,953,684 (+)	NCBI

RefSeq Acc Id:

XR_005488846

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,029 - 42,449,687 (+)	NCBI
mRatBN7.2	9	34,447,023 - 34,953,684 (+)	NCBI

RefSeq Acc Id:

XR_010054563

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,029 - 42,449,687 (+)	NCBI

RefSeq Acc Id:

XR_010054564

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	41,943,029 - 42,449,687 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_579852	(Get FASTA)	NCBI Sequence Viewer
	XP_038938917	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL09360	(Get FASTA)	NCBI Sequence Viewer
	EDL99324	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000016579
	ENSRNOP00000016579.3
	ENSRNOP00000100781
GenBank Protein	Q920F3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_579852 ⟸ NM_133318

- UniProtKB:

Q920F3 (UniProtKB/Swiss-Prot), A6IN86 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGRKEDEEKKYLDVISNKNIKLSERV
LIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLS
DELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSEESGRGRGIRG
RGIRITPTAPSRGRGGAVPPPPPPGRGVLTPRGTTVTRGALPVPPVARGVPTPRARGTAAVPGY
RAPPPPAPEAYEEYGYDDGYGGEYDDQTYEAYDNSYVTPTQSVPEYYDYGHGVNEDAYDSYAPE
EWTTTRSSLKAPPPRSARGGYREHPYGRY

hide sequence

Ensembl Acc Id:

ENSRNOP00000016579 ⟸ ENSRNOT00000016578

RefSeq Acc Id:	XP_038938917 ⟸ XM_039082989
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000076472 ⟸ ENSRNOT00000113927

Ensembl Acc Id:

ENSRNOP00000095124 ⟸ ENSRNOT00000107830

Ensembl Acc Id:

ENSRNOP00000100781 ⟸ ENSRNOT00000154861

Ensembl Acc Id:

ENSRNOP00000101510 ⟸ ENSRNOT00000146709

Protein Domains

K Homology KH KHDRBS Qua1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q920F3-F1-model_v2	AlphaFold	Q920F3	1-349	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621738	AgrOrtholog
BioCyc Gene	G2FUF-27887	BioCyc
Ensembl Genes	ENSRNOG00000012284	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000016578	ENTREZGENE
	ENSRNOT00000016578.6	UniProtKB/Swiss-Prot
	ENSRNOT00000154861	ENTREZGENE
Gene3D-CATH	3.30.1370.10	UniProtKB/Swiss-Prot
InterPro	BBP-like	UniProtKB/Swiss-Prot
	KH_1_KHDC4/BBP-like	UniProtKB/Swiss-Prot
	KH_dom	UniProtKB/Swiss-Prot
	KH_dom_type_1_sf	UniProtKB/Swiss-Prot
	Qua1_dom	UniProtKB/Swiss-Prot
	Sam68-YY	UniProtKB/Swiss-Prot
KEGG Report	rno:170843	UniProtKB/Swiss-Prot
NCBI Gene	170843	ENTREZGENE
PANTHER	KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 2	UniProtKB/Swiss-Prot
	PTHR11208	UniProtKB/Swiss-Prot
Pfam	KH-I_KHDC4-BBP	UniProtKB/Swiss-Prot
	Qua1	UniProtKB/Swiss-Prot
	Sam68-YY	UniProtKB/Swiss-Prot
PhenoGen	Khdrbs2	PhenoGen
PROSITE	KH_TYPE_1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000012284	RatGTEx
SMART	SM00322	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54791	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y5X2_RAT	UniProtKB/TrEMBL
	A0A8I6AM17_RAT	UniProtKB/TrEMBL
	A0ABK0L0F6_RAT	UniProtKB/TrEMBL
	A0ABK0L7C9_RAT	UniProtKB/TrEMBL
	A6IN86	ENTREZGENE, UniProtKB/TrEMBL
	KHDR2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-01	Khdrbs2	KH RNA binding domain containing, signal transduction associated 2	Khdrbs2	KH domain containing, RNA binding, signal transduction associated 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Khdrbs2	KH domain containing, RNA binding, signal transduction associated 2	Slm1	Sam68-like mammalian protein 1	Symbol and Name updated	1299863	APPROVED
2002-08-07	Slm1	Sam68-like mammalian protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed primarily in brain and to a lesser degree in testis	1358238

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - CTD