Gabrg3 (gamma-aminobutyric acid type A receptor subunit gamma 3) - Rat Genome Database

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Gene: Gabrg3 (gamma-aminobutyric acid type A receptor subunit gamma 3) Rattus norvegicus
Analyze
Symbol: Gabrg3
Name: gamma-aminobutyric acid type A receptor subunit gamma 3
RGD ID: 621735
Description: Enables GABA-A receptor activity and GABA-gated chloride ion channel activity. Involved in response to xenobiotic stimulus. Predicted to be located in microtubule cytoskeleton; nucleolus; and postsynaptic membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in several cellular components, including GABA-ergic synapse; dendrite membrane; and synaptic membrane. Orthologous to human GABRG3 (gamma-aminobutyric acid type A receptor subunit gamma3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GABA(A) receptor subunit gamma-3; GABA-alpha receptor gamma-3 subunit; GABAAR subunit gamma-3; gamma-aminobutyric acid (GABA) A receptor, gamma 3; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3; gamma-aminobutyric acid A receptor, gamma 3; gamma-aminobutyric acid receptor subunit gamma-3; gamma-aminobutyric acid type A receptor gamma 3 subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81116,763,332 - 117,386,770 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1116,763,129 - 117,382,536 (-)EnsemblGRCr8
mRatBN7.21107,627,450 - 108,247,483 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1107,627,390 - 108,246,763 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1113,001,526 - 113,624,939 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01121,473,413 - 122,097,448 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01114,722,366 - 115,345,770 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01112,158,525 - 112,812,267 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1112,158,519 - 112,811,936 (-)Ensemblrn6Rnor6.0
Rnor_5.01113,167,714 - 113,822,248 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41108,189,311 - 108,821,051 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1101,806,875 - 102,419,541 (-)NCBICelera
RGSC_v3.11108,267,653 - 108,899,394 (-)NCBI
Cytogenetic Map1q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The third gamma subunit of the gamma-aminobutyric acid type A receptor family. Herb A, etal., Proc Natl Acad Sci U S A 1992 Feb 15;89(4):1433-7.
4. The gamma 3-subunit of the GABAA-receptor confers sensitivity to benzodiazepine receptor ligands. Knoflach F, etal., FEBS Lett 1991 Nov 18;293(1-2):191-4.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Incorporation of the pi subunit into functional gamma-aminobutyric Acid(A) receptors. Neelands TR and Macdonald RL, Mol Pharmacol. 1999 Sep;56(3):598-610. doi: 10.1124/mol.56.3.598.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:27681   PMID:10536013  


Genomics

Comparative Map Data
Gabrg3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81116,763,332 - 117,386,770 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1116,763,129 - 117,382,536 (-)EnsemblGRCr8
mRatBN7.21107,627,450 - 108,247,483 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1107,627,390 - 108,246,763 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1113,001,526 - 113,624,939 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01121,473,413 - 122,097,448 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01114,722,366 - 115,345,770 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01112,158,525 - 112,812,267 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1112,158,519 - 112,811,936 (-)Ensemblrn6Rnor6.0
Rnor_5.01113,167,714 - 113,822,248 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41108,189,311 - 108,821,051 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1101,806,875 - 102,419,541 (-)NCBICelera
RGSC_v3.11108,267,653 - 108,899,394 (-)NCBI
Cytogenetic Map1q22NCBI
GABRG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381526,971,181 - 27,541,984 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1526,971,181 - 27,541,984 (+)Ensemblhg38GRCh38
GRCh371527,216,328 - 27,787,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361524,799,263 - 25,168,899 (+)NCBIBuild 36Build 36hg18NCBI36
Build 361525,399,391 - 25,451,729 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341525,399,390 - 25,451,722NCBI
Celera155,377,602 - 5,938,310 (+)NCBICelera
Cytogenetic Map15q12NCBI
HuRef155,344,440 - 5,905,082 (+)NCBIHuRef
CHM1_11527,165,969 - 27,727,967 (+)NCBICHM1_1
T2T-CHM13v2.01524,712,759 - 25,284,426 (+)NCBIT2T-CHM13v2.0
Gabrg3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39756,366,211 - 57,037,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl756,366,213 - 57,036,936 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38756,716,463 - 57,387,215 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl756,716,465 - 57,387,188 (-)Ensemblmm10GRCm38
MGSCv37763,979,612 - 64,642,241 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36756,592,261 - 57,254,817 (-)NCBIMGSCv36mm8
Celera754,048,949 - 54,699,615 (-)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.48NCBI
Gabrg3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555331,962,273 - 2,495,876 (-)Ensembl
ChiLan1.0NW_0049555331,962,175 - 2,495,877 (-)NCBIChiLan1.0ChiLan1.0
GABRG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2167,748,343 - 8,306,630 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11511,389,636 - 11,947,679 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0152,371,468 - 2,932,250 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11524,703,846 - 24,960,913 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1524,409,611 - 24,959,987 (+)EnsemblpanPan2panpan1.1
GABRG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1332,956,061 - 33,641,971 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl332,964,122 - 33,642,686 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha335,646,875 - 36,332,262 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0333,293,570 - 33,977,676 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl333,300,191 - 33,978,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1332,834,310 - 33,518,364 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0333,083,854 - 33,780,951 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0333,186,801 - 33,927,787 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gabrg3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640121,329,746 - 121,903,607 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647139,185,702 - 39,751,187 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647139,184,683 - 39,256,439 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1139,857,095 - 140,464,579 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11139,855,461 - 140,464,592 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21156,085,367 - 156,136,061 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12654,570,497 - 55,126,712 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605437,445,615 - 37,956,789 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabrg3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248961,392,932 - 1,973,363 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Gabrg3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12141,912,705 - 142,512,196 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gabrg3
4261 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:33
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000019971
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1112521556157521556Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)1108680016153680016Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
631569Bp93Blood pressure QTL 930.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611131244255Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1112521556157521556Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1111949780160574007Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1111404407142582336Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat

Markers in Region
D1Rat345  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81117,263,673 - 117,263,798 (+)Marker Load Pipeline
mRatBN7.21108,127,943 - 108,128,068 (+)MAPPERmRatBN7.2
Rnor_6.01112,693,166 - 112,693,290NCBIRnor6.0
Rnor_5.01113,693,987 - 113,694,113NCBIRnor5.0
Rnor_5.01113,693,988 - 113,694,113NCBIRnor5.0
RGSC_v3.41108,699,830 - 108,699,954UniSTSRGSC3.4
RGSC_v3.41108,699,829 - 108,699,954RGDRGSC3.4
Celera1102,301,254 - 102,301,378UniSTS
RGSC_v3.11108,778,172 - 108,778,297RGD
SHRSP x BN Map153.8RGD
SHRSP x BN Map153.8UniSTS
Cytogenetic Map1q22UniSTS
AU048232  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81117,214,226 - 117,214,390 (+)Marker Load Pipeline
mRatBN7.21108,078,502 - 108,078,666 (+)MAPPERmRatBN7.2
Rnor_6.01112,643,721 - 112,643,884NCBIRnor6.0
Rnor_5.01113,645,289 - 113,645,452UniSTSRnor5.0
RGSC_v3.41108,650,341 - 108,650,504UniSTSRGSC3.4
Celera1102,251,910 - 102,252,073UniSTS
Cytogenetic Map1q22UniSTS
RH137869  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21108,105,589 - 108,105,812 (+)MAPPERmRatBN7.2
Rnor_6.01112,670,810 - 112,671,032NCBIRnor6.0
Rnor_5.01113,672,280 - 113,672,502UniSTSRnor5.0
RGSC_v3.41108,677,430 - 108,677,652UniSTSRGSC3.4
Celera1102,278,999 - 102,279,221UniSTS
RH 3.4 Map11617.6UniSTS
Cytogenetic Map1q22UniSTS
BF391052  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21107,801,019 - 107,801,173 (+)MAPPERmRatBN7.2
Rnor_6.01112,369,060 - 112,369,213NCBIRnor6.0
Rnor_5.01113,370,477 - 113,370,630UniSTSRnor5.0
RGSC_v3.41108,369,216 - 108,369,369UniSTSRGSC3.4
Celera1101,974,047 - 101,974,200UniSTS
RH 3.4 Map11616.3UniSTS
Cytogenetic Map1q22UniSTS
BM387166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21108,060,638 - 108,060,801 (+)MAPPERmRatBN7.2
Rnor_6.01112,625,868 - 112,626,030NCBIRnor6.0
Rnor_5.01113,627,460 - 113,627,622UniSTSRnor5.0
RGSC_v3.41108,632,357 - 108,632,519UniSTSRGSC3.4
Celera1102,234,027 - 102,234,189UniSTS
RH 3.4 Map1964.11UniSTS
Cytogenetic Map1q22UniSTS
AU048805  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21108,237,671 - 108,237,797 (+)MAPPERmRatBN7.2
Rnor_6.01112,802,889 - 112,803,014NCBIRnor6.0
Rnor_5.01113,813,434 - 113,813,559UniSTSRnor5.0
RGSC_v3.41108,811,957 - 108,812,082UniSTSRGSC3.4
Celera1102,410,471 - 102,410,596UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 16 118 33 33 20 10 20 1 87 32 111 26 59 13 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000019971   ⟹   ENSRNOP00000019971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1116,763,129 - 117,382,536 (-)Ensembl
mRatBN7.2 Ensembl1107,627,390 - 107,869,277 (-)Ensembl
Rnor_6.0 Ensembl1112,158,530 - 112,436,794 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093339   ⟹   ENSRNOP00000076184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1116,763,129 - 117,382,430 (-)Ensembl
mRatBN7.2 Ensembl1107,627,390 - 108,246,763 (-)Ensembl
Rnor_6.0 Ensembl1112,158,519 - 112,811,936 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112854   ⟹   ENSRNOP00000085675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1117,183,188 - 117,382,430 (-)Ensembl
mRatBN7.2 Ensembl1108,047,464 - 108,246,763 (-)Ensembl
RefSeq Acc Id: NM_024370   ⟹   NP_077346
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81116,763,358 - 117,382,457 (-)NCBI
mRatBN7.21107,627,619 - 108,246,737 (-)NCBI
Rnor_6.01112,158,530 - 112,811,954 (-)NCBI
Rnor_5.01113,167,714 - 113,822,248 (-)NCBI
RGSC_v3.41108,189,311 - 108,821,051 (-)RGD
Celera1101,806,875 - 102,419,541 (-)RGD
Sequence:
RefSeq Acc Id: XM_017589765   ⟹   XP_017445254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81116,763,332 - 117,386,770 (-)NCBI
mRatBN7.21107,627,450 - 108,247,483 (-)NCBI
Rnor_6.01112,158,525 - 112,812,267 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_077346 (Get FASTA)   NCBI Sequence Viewer  
  XP_017445254 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41181 (Get FASTA)   NCBI Sequence Viewer  
  CAA44930 (Get FASTA)   NCBI Sequence Viewer  
  EDL86452 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019971
  ENSRNOP00000076184
  ENSRNOP00000076184.1
GenBank Protein P28473 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077346   ⟸   NM_024370
- Peptide Label: precursor
- UniProtKB: P28473 (UniProtKB/Swiss-Prot),   A6KD36 (UniProtKB/TrEMBL),   A0A0A0MXX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445254   ⟸   XM_017589765
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000076184   ⟸   ENSRNOT00000093339
Ensembl Acc Id: ENSRNOP00000019971   ⟸   ENSRNOT00000019971
Ensembl Acc Id: ENSRNOP00000085675   ⟸   ENSRNOT00000112854
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28473-F1-model_v2 AlphaFold P28473 1-467 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621735 AgrOrtholog
BioCyc Gene G2FUF-59447 BioCyc
Ensembl Genes ENSRNOG00000014862 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019971 ENTREZGENE
  ENSRNOT00000093339 ENTREZGENE
  ENSRNOT00000093339.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot
  2.70.170.10 UniProtKB/Swiss-Prot
InterPro GABAA/Glycine_rcpt UniProtKB/Swiss-Prot
  GABBAg3_rcpt UniProtKB/Swiss-Prot
  GABBAg_rcpt UniProtKB/Swiss-Prot
  Neur_chan_lig-bd UniProtKB/Swiss-Prot
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot
  Neur_channel UniProtKB/Swiss-Prot
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot
  Neuro_actylchol_rec UniProtKB/Swiss-Prot
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot
KEGG Report rno:79211 UniProtKB/Swiss-Prot
NCBI Gene 79211 ENTREZGENE
PANTHER PTHR18945 UniProtKB/Swiss-Prot
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot
  Neur_chan_memb UniProtKB/Swiss-Prot
PhenoGen Gabrg3 PhenoGen
PRINTS GABAARECEPTR UniProtKB/Swiss-Prot
  GABAARGAMMA UniProtKB/Swiss-Prot
  GABAARGAMMA3 UniProtKB/Swiss-Prot
  NRIONCHANNEL UniProtKB/Swiss-Prot
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014862 RatGTEx
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot
  SSF90112 UniProtKB/Swiss-Prot
UniProt A0A0A0MXX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZR3_RAT UniProtKB/TrEMBL
  A6KD36 ENTREZGENE, UniProtKB/TrEMBL
  GBRG3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Gabrg3  gamma-aminobutyric acid type A receptor subunit gamma 3  Gabrg3  gamma-aminobutyric acid type A receptor gamma 3 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Gabrg3  gamma-aminobutyric acid type A receptor gamma 3 subunit  Gabrg3  gamma-aminobutyric acid (GABA) A receptor, gamma 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-04 Gabrg3  gamma-aminobutyric acid (GABA) A receptor, gamma 3  Gabrg3  gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Gabrg3  gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3    GABA-alpha receptor gamma-3 subunit  Name updated 1299863 APPROVED
2002-08-07 Gabrg3  GABA-alpha receptor gamma-3 subunit      Symbol and Name status set to provisional 70820 PROVISIONAL