Pip4k2c (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Pip4k2c (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma) Rattus norvegicus
Analyze
Symbol: Pip4k2c
Name: phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
RGD ID: 621711
Description: Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; negative regulation of insulin receptor signaling pathway; and positive regulation of autophagosome assembly. Predicted to be located in autophagosome. Predicted to be active in plasma membrane. Orthologous to human PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: phosphatidylinositol 5-phosphate 4-kinase type II gamma; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; phosphatidylinositol-4-phosphate 5-kinase, type II, gamma; phosphatidylinositol-5-phosphate 4-kinase type-2 gamma; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gamma; Pip5k2c
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,905,322 - 64,920,380 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl764,905,328 - 64,920,373 (-)EnsemblGRCr8
mRatBN7.2763,020,004 - 63,035,086 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,020,000 - 63,035,078 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx764,909,290 - 64,924,337 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,111,704 - 67,126,752 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,912,777 - 66,927,839 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,483,948 - 70,498,995 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,483,942 - 70,498,995 (-)Ensemblrn6Rnor6.0
Rnor_5.0770,661,192 - 70,676,538 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,151,468 - 67,166,564 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,161,604 - 60,176,643 (-)NCBICelera
RGSC_v3.1767,172,688 - 67,187,294 (-)NCBI
Cytogenetic Map7q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A novel phosphatidylinositol-5-phosphate 4-kinase (phosphatidylinositol-phosphate kinase IIgamma) is phosphorylated in the endoplasmic reticulum in response to mitogenic signals. Itoh T, etal., J Biol Chem 1998 Aug 7;273(32):20292-9.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:18255255   PMID:18570454   PMID:19056867   PMID:23376485   PMID:23758345   PMID:25495341   PMID:25578879  


Genomics

Comparative Map Data
Pip4k2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,905,322 - 64,920,380 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl764,905,328 - 64,920,373 (-)EnsemblGRCr8
mRatBN7.2763,020,004 - 63,035,086 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,020,000 - 63,035,078 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx764,909,290 - 64,924,337 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,111,704 - 67,126,752 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,912,777 - 66,927,839 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,483,948 - 70,498,995 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,483,942 - 70,498,995 (-)Ensemblrn6Rnor6.0
Rnor_5.0770,661,192 - 70,676,538 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,151,468 - 67,166,564 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,161,604 - 60,176,643 (-)NCBICelera
RGSC_v3.1767,172,688 - 67,187,294 (-)NCBI
Cytogenetic Map7q22NCBI
PIP4K2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,591,192 - 57,603,418 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,591,174 - 57,603,418 (+)Ensemblhg38GRCh38
GRCh371257,984,975 - 57,997,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,271,324 - 56,283,298 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341256,271,323 - 56,283,296NCBI
Celera1257,640,774 - 57,653,027 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1255,022,647 - 55,034,898 (+)NCBIHuRef
CHM1_11257,952,773 - 57,965,027 (+)NCBICHM1_1
T2T-CHM13v2.01257,559,429 - 57,571,638 (+)NCBIT2T-CHM13v2.0
Pip4k2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,032,936 - 127,047,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,032,936 - 127,047,454 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3810127,197,067 - 127,211,628 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,197,067 - 127,211,585 (-)Ensemblmm10GRCm38
MGSCv3710126,634,123 - 126,648,678 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610126,600,016 - 126,614,495 (-)NCBIMGSCv36mm8
Celera10129,590,131 - 129,604,615 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Pip4k2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,315,376 - 5,327,617 (+)Ensembl
ChiLan1.0NW_0049554585,315,083 - 5,327,617 (+)NCBIChiLan1.0ChiLan1.0
PIP4K2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,731,185 - 36,749,881 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,727,956 - 36,746,652 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,323,346 - 31,335,626 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,582,725 - 31,594,808 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,584,534 - 31,594,808 (-)EnsemblpanPan2panpan1.1
PIP4K2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,670,076 - 1,680,975 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,672,380 - 1,680,840 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha101,732,572 - 1,744,119 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0101,678,750 - 1,690,303 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,678,723 - 1,690,295 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,656,535 - 1,668,086 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,898,309 - 1,909,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0102,023,523 - 2,035,070 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pip4k2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,122,179 - 57,133,168 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,737,034 - 1,748,057 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,737,088 - 1,748,056 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP4K2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,854,316 - 22,867,028 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1522,854,142 - 22,867,032 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,821,711 - 24,826,063 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIP4K2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,499,360 - 53,511,610 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,499,432 - 53,509,799 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037192,450,528 - 192,462,783 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pip4k2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,359,888 - 10,370,909 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462480210,359,891 - 10,370,931 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pip4k2c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11205,633,708 - 205,648,195 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pip4k2c
78 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:467
Count of miRNA genes:216
Interacting mature miRNAs:270
Transcripts:ENSRNOT00000067774
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
RH137001  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,020,091 - 63,020,271 (+)MAPPERmRatBN7.2
Rnor_6.0770,484,032 - 70,484,211NCBIRnor6.0
Rnor_5.0770,661,276 - 70,661,455UniSTSRnor5.0
RGSC_v3.4767,151,552 - 67,151,731UniSTSRGSC3.4
Celera760,161,688 - 60,161,867UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000067774   ⟹   ENSRNOP00000061758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,905,328 - 64,920,373 (-)Ensembl
mRatBN7.2 Ensembl763,020,000 - 63,035,078 (-)Ensembl
Rnor_6.0 Ensembl770,483,942 - 70,498,992 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079327   ⟹   ENSRNOP00000075530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,020,140 - 63,035,078 (-)Ensembl
Rnor_6.0 Ensembl770,484,439 - 70,498,995 (-)Ensembl
RefSeq Acc Id: NM_080480   ⟹   NP_536728
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,905,325 - 64,920,373 (-)NCBI
mRatBN7.2763,020,008 - 63,035,056 (-)NCBI
Rnor_6.0770,483,948 - 70,498,995 (-)NCBI
Rnor_5.0770,661,192 - 70,676,538 (-)NCBI
RGSC_v3.4767,151,468 - 67,166,564 (-)RGD
Celera760,161,604 - 60,176,643 (-)RGD
Sequence:
RefSeq Acc Id: XM_039078315   ⟹   XP_038934243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,905,322 - 64,920,380 (-)NCBI
mRatBN7.2763,020,034 - 63,034,943 (-)NCBI
Protein Sequences
Protein RefSeqs NP_536728 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934243 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC40202 (Get FASTA)   NCBI Sequence Viewer  
  EDM16487 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061758
GenBank Protein O88370 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_536728   ⟸   NM_080480
- UniProtKB: O88370 (UniProtKB/Swiss-Prot),   G3V9W5 (UniProtKB/TrEMBL),   A6HQT5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075530   ⟸   ENSRNOT00000079327
Ensembl Acc Id: ENSRNOP00000061758   ⟸   ENSRNOT00000067774
RefSeq Acc Id: XP_038934243   ⟸   XM_039078315
- Peptide Label: isoform X1
- UniProtKB: O88370 (UniProtKB/Swiss-Prot)
Protein Domains
PIPK

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88370-F1-model_v2 AlphaFold O88370 1-420 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695253
Promoter ID:EPDNEW_R5778
Type:initiation region
Name:Pip4k2c_1
Description:phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0770,498,994 - 70,499,054EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621711 AgrOrtholog
BioCyc Gene G2FUF-33758 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
Ensembl Genes ENSRNOG00000005138 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000067774 ENTREZGENE
Gene3D-CATH 2-Layer Sandwich UniProtKB/Swiss-Prot
  3.30.800.10 UniProtKB/Swiss-Prot
InterPro PInositol-4-P-4/5-kinase_C_sf UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase_core UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase_N UniProtKB/Swiss-Prot
KEGG Report rno:140607 UniProtKB/Swiss-Prot
NCBI Gene 140607 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 GAMMA UniProtKB/Swiss-Prot
  PTHR23086 UniProtKB/Swiss-Prot
Pfam PIP5K UniProtKB/Swiss-Prot
PhenoGen Pip4k2c PhenoGen
PROSITE PIPK UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005138 RatGTEx
SMART PIPKc UniProtKB/Swiss-Prot
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot
UniProt A6HQT5 ENTREZGENE, UniProtKB/TrEMBL
  G3V9W5 ENTREZGENE, UniProtKB/TrEMBL
  O88370 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-20 Pip4k2c  phosphatidylinositol-5-phosphate 4-kinase type 2 gamma  Pip4k2c  phosphatidylinositol-5-phosphate 4-kinase, type II, gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Pip4k2c  phosphatidylinositol-5-phosphate 4-kinase, type II, gamma  Pip5k2c  phosphatidylinositol-4-phosphate 5-kinase, type II, gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Pip5k2c  phosphatidylinositol-4-phosphate 5-kinase, type II, gamma      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Pip5k2c  phosphatidylinositol-4-phosphate 5-kinase, type II, gamma      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology has similarity to phosphatidylinositol5-phosphate 4-kinase IIalpha and IIbeta isoforms 633581