Ptbp3 (polypyrimidine tract binding protein 3) - Rat Genome Database

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Pathways
Gene: Ptbp3 (polypyrimidine tract binding protein 3) Rattus norvegicus
Analyze
Symbol: Ptbp3
Name: polypyrimidine tract binding protein 3
RGD ID: 621671
Description: Predicted to enable mRNA binding activity. Involved in regulation of cell differentiation. Predicted to be active in nucleus. Orthologous to human PTBP3 (polypyrimidine tract binding protein 3); INTERACTS WITH 1,2-dimethylhydrazine; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: polypyrimidine tract-binding protein 3; regulator of differentiation (in S. pombe) 1; regulator of differentiation 1; Rod1; ROD1 regulator of differentiation 1; ROD1 regulator of differentiation 1 (S. pombe)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8579,108,376 - 79,194,533 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl579,108,376 - 79,194,508 (-)EnsemblGRCr8
mRatBN7.2574,313,367 - 74,399,439 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl574,315,101 - 74,399,791 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx576,218,248 - 76,304,318 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0578,039,883 - 78,125,953 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0578,012,048 - 78,098,119 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0576,670,074 - 76,756,196 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl576,673,990 - 76,756,147 (-)Ensemblrn6Rnor6.0
Rnor_5.0580,807,961 - 80,893,974 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4577,551,329 - 77,635,122 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera573,136,368 - 73,217,909 (-)NCBICelera
RGSC_v3.1577,556,441 - 77,640,235 (-)NCBI
Cytogenetic Map5q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4,6-tribromophenol  (ISO)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
alpha-phellandrene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
hypochlorous acid  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
rimonabant  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
troglitazone  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Isolation of a mammalian homologue of a fission yeast differentiation regulator. Yamamoto H, etal., Mol Cell Biol 1999 May;19(5):3829-41.
Additional References at PubMed
PMID:18335065   PMID:22658674   PMID:22681889   PMID:23636947  


Genomics

Comparative Map Data
Ptbp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8579,108,376 - 79,194,533 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl579,108,376 - 79,194,508 (-)EnsemblGRCr8
mRatBN7.2574,313,367 - 74,399,439 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl574,315,101 - 74,399,791 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx576,218,248 - 76,304,318 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0578,039,883 - 78,125,953 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0578,012,048 - 78,098,119 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0576,670,074 - 76,756,196 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl576,673,990 - 76,756,147 (-)Ensemblrn6Rnor6.0
Rnor_5.0580,807,961 - 80,893,974 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4577,551,329 - 77,635,122 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera573,136,368 - 73,217,909 (-)NCBICelera
RGSC_v3.1577,556,441 - 77,640,235 (-)NCBI
Cytogenetic Map5q24NCBI
PTBP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389112,217,715 - 112,379,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9112,215,071 - 112,333,695 (-)Ensemblhg38GRCh38
GRCh379114,979,995 - 115,095,944 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369114,020,536 - 114,135,733 (-)NCBIBuild 36Build 36hg18NCBI36
Build 349112,064,495 - 112,175,460NCBI
Celera985,479,714 - 85,594,900 (-)NCBICelera
Cytogenetic Map9q32NCBI
HuRef984,578,801 - 84,694,587 (-)NCBIHuRef
CHM1_19115,126,396 - 115,242,542 (-)NCBICHM1_1
T2T-CHM13v2.09124,388,866 - 124,504,825 (-)NCBIT2T-CHM13v2.0
Ptbp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39459,471,868 - 59,549,288 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl459,471,868 - 59,549,364 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38459,471,868 - 59,549,378 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl459,471,868 - 59,549,364 (-)Ensemblmm10GRCm38
MGSCv37459,484,740 - 59,562,236 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36459,569,120 - 59,643,340 (-)NCBIMGSCv36mm8
Celera459,388,969 - 59,466,480 (-)NCBICelera
Cytogenetic Map4B3NCBI
cM Map432.57NCBI
Ptbp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541915,000,072 - 15,101,588 (+)Ensembl
ChiLan1.0NW_00495541915,002,780 - 15,101,588 (+)NCBIChiLan1.0ChiLan1.0
PTBP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21127,053,960 - 27,213,681 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1927,056,557 - 27,216,931 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0983,348,909 - 83,508,736 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19111,506,100 - 111,664,928 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9111,511,371 - 111,563,893 (-)EnsemblpanPan2panpan1.1
PTBP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11166,727,670 - 66,847,755 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1166,732,583 - 66,847,303 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1165,136,112 - 65,291,068 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01167,861,465 - 68,012,011 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1167,861,472 - 67,980,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11166,375,784 - 66,528,469 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01166,399,432 - 66,551,921 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01167,143,518 - 67,296,220 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ptbp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947182,076,874 - 182,174,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365591,091,494 - 1,186,440 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365591,091,575 - 1,186,452 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTBP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,986,564 - 253,093,063 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11252,986,716 - 253,093,059 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21283,772,669 - 283,878,514 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTBP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11227,179,727 - 27,295,046 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1227,179,747 - 27,289,764 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603515,489,829 - 15,605,815 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptbp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476022,632,048 - 22,747,156 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476022,632,125 - 22,751,823 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ptbp3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1191,886,503 - 91,967,503 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ptbp3
572 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:368
Count of miRNA genes:218
Interacting mature miRNAs:244
Transcripts:ENSRNOT00000022107
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)573779642103472210Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 172 91 90 59 92 59 6 358 192 11 151 83 93 31 23 23

Sequence


Ensembl Acc Id: ENSRNOT00000022107   ⟹   ENSRNOP00000022107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl579,108,376 - 79,194,437 (-)Ensembl
mRatBN7.2 Ensembl574,315,101 - 74,399,791 (-)Ensembl
Rnor_6.0 Ensembl576,673,990 - 76,756,140 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089251   ⟹   ENSRNOP00000069354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl579,108,376 - 79,194,508 (-)Ensembl
mRatBN7.2 Ensembl574,315,101 - 74,372,181 (-)Ensembl
Rnor_6.0 Ensembl576,674,886 - 76,756,147 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116337   ⟹   ENSRNOP00000092713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl579,108,376 - 79,194,387 (-)Ensembl
mRatBN7.2 Ensembl574,315,101 - 74,399,791 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118205   ⟹   ENSRNOP00000084394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl574,360,980 - 74,398,690 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000136659   ⟹   ENSRNOP00000098748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl579,108,376 - 79,193,982 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000157596   ⟹   ENSRNOP00000104044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl579,108,376 - 79,194,437 (-)Ensembl
RefSeq Acc Id: NM_031346   ⟹   NP_112636
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8579,108,376 - 79,194,440 (-)NCBI
mRatBN7.2574,313,367 - 74,399,438 (-)NCBI
Rnor_6.0576,673,990 - 76,756,140 (-)NCBI
Rnor_5.0580,807,961 - 80,893,974 (-)NCBI
RGSC_v3.4577,551,329 - 77,635,122 (-)RGD
Celera573,136,368 - 73,217,909 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238206   ⟹   XP_006238268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8579,108,376 - 79,194,532 (-)NCBI
mRatBN7.2574,313,536 - 74,399,439 (-)NCBI
Rnor_6.0576,670,074 - 76,756,196 (-)NCBI
Rnor_5.0580,807,961 - 80,893,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238207   ⟹   XP_006238269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8579,108,376 - 79,194,533 (-)NCBI
mRatBN7.2574,313,536 - 74,399,439 (-)NCBI
Rnor_6.0576,670,074 - 76,756,196 (-)NCBI
Rnor_5.0580,807,961 - 80,893,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110848   ⟹   XP_038966776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8579,108,376 - 79,194,533 (-)NCBI
mRatBN7.2574,313,536 - 74,399,353 (-)NCBI
RefSeq Acc Id: XM_063288481   ⟹   XP_063144551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8579,108,376 - 79,191,332 (-)NCBI
RefSeq Acc Id: NP_112636   ⟸   NM_031346
- UniProtKB: Q9Z118 (UniProtKB/Swiss-Prot),   A0A8L2UJS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238269   ⟸   XM_006238207
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JV54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238268   ⟸   XM_006238206
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JV54 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069354   ⟸   ENSRNOT00000089251
Ensembl Acc Id: ENSRNOP00000022107   ⟸   ENSRNOT00000022107
RefSeq Acc Id: XP_038966776   ⟸   XM_039110848
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AIH3 (UniProtKB/TrEMBL),   A6KDW6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092713   ⟸   ENSRNOT00000116337
Ensembl Acc Id: ENSRNOP00000084394   ⟸   ENSRNOT00000118205
RefSeq Acc Id: XP_063144551   ⟸   XM_063288481
- Peptide Label: isoform X3
- UniProtKB: A0A8L2UJS5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000098748   ⟸   ENSRNOT00000136659
Ensembl Acc Id: ENSRNOP00000104044   ⟸   ENSRNOT00000157596
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z118-F1-model_v2 AlphaFold Q9Z118 1-523 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693771
Promoter ID:EPDNEW_R4295
Type:multiple initiation site
Name:Ptbp3_1
Description:polypyrimidine tract binding protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0576,756,140 - 76,756,200EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621671 AgrOrtholog
BioCyc Gene G2FUF-41150 BioCyc
Ensembl Genes ENSRNOG00000016334 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022107 ENTREZGENE
  ENSRNOT00000089251 ENTREZGENE
  ENSRNOT00000116337 ENTREZGENE
  ENSRNOT00000157596 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
InterPro HnRNP-L/PTB UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  PTBP1_RRM UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  ROD1_RRM1 UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
KEGG Report rno:83515 UniProtKB/Swiss-Prot
NCBI Gene 83515 ENTREZGENE
PANTHER MATRIN 3/NUCLEAR PROTEIN 220-RELATED UniProtKB/Swiss-Prot
Pfam RRM_1 UniProtKB/Swiss-Prot
  RRM_5 UniProtKB/Swiss-Prot
  RRM_8 UniProtKB/Swiss-Prot
PhenoGen Ptbp3 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016334 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt A0A0G2JV54 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIH3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UJS5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LDE8_RAT UniProtKB/TrEMBL
  A0ABK0LGZ4_RAT UniProtKB/TrEMBL
  A6KDW6 ENTREZGENE, UniProtKB/TrEMBL
  PTBP3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-06 Ptbp3  polypyrimidine tract binding protein 3  Rod1  ROD1 regulator of differentiation 1 (S. pombe)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rod1  ROD1 regulator of differentiation 1 (S. pombe)    regulator of differentiation (in S. pombe) 1  Name updated 1299863 APPROVED
2002-08-07 Rod1  regulator of differentiation (in S. pombe) 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains four RNA binding domains 704461
gene_expression expressed in hematopoetic cells and tissues 704461