Tpm3 (tropomyosin 3) - Rat Genome Database

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Gene: Tpm3 (tropomyosin 3) Rattus norvegicus
Analyze
Symbol: Tpm3
Name: tropomyosin 3
RGD ID: 621546
Description: Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization and muscle contraction. Located in brush border. Human ortholog(s) of this gene implicated in congenital myopathy 4A and nemaline myopathy 1. Orthologous to human TPM3 (tropomyosin 3); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; thyroid cancer pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: gamma-tropomyosin; nonmuscle tropomyosin 5; TM30nm; Tpm5; tropomyosin 3, gamma; tropomyosin alpha-3 chain; tropomyosin non-muscle; tropomyosin-3; tropomyosin-5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Tpm3_v1   Tpm3_v3   Tpm3_v2  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,812,534 - 177,842,661 (+)NCBIGRCr8
mRatBN7.22175,517,198 - 175,545,014 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,517,226 - 175,545,013 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,663,687 - 182,691,187 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,686,074 - 180,713,576 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,286,696 - 175,314,195 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,423,534 - 189,451,340 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,423,559 - 189,451,029 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,856,598 - 208,884,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,303,994 - 182,324,994 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12182,254,141 - 182,273,295 (+)NCBI
Celera2169,456,120 - 169,483,632 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
acetamide  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
buspirone  (EXP)
butanal  (ISO)
caffeine  (ISO)
cannabidiol  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
ciglitazone  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
clozapine  (ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dimethyl sulfoxide  (EXP)
diuron  (ISO)
doxorubicin  (EXP,ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gallic acid  (ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (ISO)
gentamycin  (EXP)
hyaluronic acid  (EXP)
hydrazine  (EXP)
hydrogen peroxide  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
levofloxacin  (EXP)
lipopolysaccharide  (EXP)
mesalamine  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
ochratoxin A  (EXP,ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
penconazole  (ISO)
perfluorooctanoic acid  (EXP)
phenethyl isothiocyanate  (ISO)
PhIP  (EXP)
pirinixic acid  (EXP,ISO)
ranitidine  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sulfasalazine  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
triticonazole  (EXP)
trovafloxacin  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification of novel alternatively spliced isoforms of the tropomyosin-encoding gene, TMnm, in the rat cochlea. Beisel KW and Kennedy JE, Gene 1994 Jun 10;143(2):251-6.
2. WNT10A/ß-catenin pathway in tumorigenesis of papillary thyroid carcinoma. Dong T, etal., Oncol Rep. 2017 Aug;38(2):1287-1294. doi: 10.3892/or.2017.5777. Epub 2017 Jul 3.
3. Splicing of two internal and four carboxyl-terminal alternative exons in nonmuscle tropomyosin 5 pre-mRNA is independently regulated during development. Dufour C, etal., J Biol Chem 1998 Jul 17;273(29):18547-55.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. A mutation in the alpha tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy. Laing NG, etal., Nat Genet. 1995 Jan;9(1):75-9.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Revenu C, etal., Mol Biol Cell. 2012 Jan;23(2):324-36. doi: 10.1091/mbc.E11-09-0765. Epub 2011 Nov 23.
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8674141   PMID:9473354   PMID:15068339   PMID:15888546   PMID:16236705   PMID:16765662   PMID:16854843   PMID:20131911   PMID:20458337   PMID:21036167   PMID:22749829   PMID:22871113  
PMID:24625528   PMID:25369766   PMID:25931508   PMID:29476059   PMID:30053369   PMID:33341060   PMID:35352799   PMID:36880246  


Genomics

Comparative Map Data
Tpm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,812,534 - 177,842,661 (+)NCBIGRCr8
mRatBN7.22175,517,198 - 175,545,014 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,517,226 - 175,545,013 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,663,687 - 182,691,187 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,686,074 - 180,713,576 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,286,696 - 175,314,195 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,423,534 - 189,451,340 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,423,559 - 189,451,029 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,856,598 - 208,884,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,303,994 - 182,324,994 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12182,254,141 - 182,273,295 (+)NCBI
Celera2169,456,120 - 169,483,632 (+)NCBICelera
Cytogenetic Map2q34NCBI
TPM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,155,308 - 154,192,100 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,155,308 - 154,194,648 (-)EnsemblGRCh38hg38GRCh38
GRCh371154,127,784 - 154,164,576 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,394,404 - 152,431,233 (-)NCBINCBI36Build 36hg18NCBI36
Celera1127,199,522 - 127,236,328 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1125,491,124 - 125,527,939 (-)NCBIHuRef
CHM1_11155,524,124 - 155,560,933 (-)NCBICHM1_1
T2T-CHM13v2.01153,292,536 - 153,329,333 (-)NCBIT2T-CHM13v2.0
Tpm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,979,958 - 90,008,209 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,979,956 - 90,008,209 (+)EnsemblGRCm39 Ensembl
GRCm38390,072,651 - 90,100,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl390,072,649 - 90,100,902 (+)EnsemblGRCm38mm10GRCm38
MGSCv37389,876,616 - 89,904,526 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36390,158,621 - 90,186,531 (+)NCBIMGSCv36mm8
Celera390,109,227 - 90,137,142 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.2NCBI
Tpm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955545715,280 - 746,575 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955545715,860 - 746,580 (-)NCBIChiLan1.0ChiLan1.0
LOC100977130
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2195,647,935 - 95,677,160 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,383,171 - 95,413,437 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,511,914 - 129,538,703 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,126,641 - 133,153,318 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,126,641 - 133,161,894 (-)Ensemblpanpan1.1panPan2
TPM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1743,039,360 - 43,067,297 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl743,039,382 - 43,067,296 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha742,535,529 - 42,557,676 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,909,915 - 42,937,862 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,885,880 - 42,937,862 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,694,385 - 42,716,552 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,747,421 - 42,769,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0743,031,793 - 43,053,953 (+)NCBIUU_Cfam_GSD_1.0
Tpm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505824,829,962 - 24,859,535 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365803,860,190 - 3,889,978 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365803,860,185 - 3,893,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,542,473 - 95,572,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1495,542,329 - 95,572,946 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24104,459,666 - 104,490,146 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TPM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,630,056 - 9,669,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,638,678 - 9,653,039 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,999,639 - 9,027,826 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248853,109,436 - 3,139,789 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248853,109,360 - 3,139,664 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tpm3
111 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:793
Count of miRNA genes:298
Interacting mature miRNAs:374
Transcripts:ENSRNOT00000023567, ENSRNOT00000023605, ENSRNOT00000029076
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921175950118Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921184114403Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2172982062175950118Rat
61457Niddm8Non-insulin dependent diabetes mellitus QTL 84.10.01blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2174543008175950118Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat

Markers in Region
RH133983  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2q34UniSTS
U04541  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,535,863 - 175,535,990 (+)MAPPERmRatBN7.2
Rnor_6.02189,442,192 - 189,442,318NCBIRnor6.0
Rnor_5.02208,875,232 - 208,875,358UniSTSRnor5.0
RGSC_v3.42182,316,145 - 182,316,271UniSTSRGSC3.4
Celera2169,474,783 - 169,474,909UniSTS
Cytogenetic Map2q34UniSTS
AW529957  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,542,718 - 175,542,893 (+)MAPPERmRatBN7.2
Rnor_6.02189,449,045 - 189,449,219NCBIRnor6.0
Rnor_5.02208,882,085 - 208,882,259UniSTSRnor5.0
RGSC_v3.42182,322,998 - 182,323,172UniSTSRGSC3.4
Celera2169,481,636 - 169,481,810UniSTS
RH 3.4 Map21164.6UniSTS
Cytogenetic Map2q34UniSTS
RH141892  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001301285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_057208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_173111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF053359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF053360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF053361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L24775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L24776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L24777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S82383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X72859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000023567   ⟹   ENSRNOP00000023567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,523,702 - 175,545,013 (+)Ensembl
Rnor_6.0 Ensembl2189,430,041 - 189,451,029 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000023605   ⟹   ENSRNOP00000023605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,523,752 - 175,542,897 (+)Ensembl
Rnor_6.0 Ensembl2189,430,083 - 189,449,223 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000029076   ⟹   ENSRNOP00000035561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,517,226 - 175,535,991 (+)Ensembl
Rnor_6.0 Ensembl2189,423,559 - 189,442,319 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101614   ⟹   ENSRNOP00000094091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,517,226 - 175,545,013 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101991   ⟹   ENSRNOP00000097306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,523,725 - 175,545,006 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112248   ⟹   ENSRNOP00000079275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,527,429 - 175,545,006 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114156   ⟹   ENSRNOP00000085183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,517,226 - 175,545,006 (+)Ensembl
RefSeq Acc Id: NM_001301285   ⟹   NP_001288214
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,814,883 - 177,833,647 (+)NCBI
mRatBN7.22175,517,226 - 175,535,995 (+)NCBI
Rnor_6.02189,423,559 - 189,442,323 (+)NCBI
Celera2169,456,120 - 169,474,914 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001301286   ⟹   NP_001288215
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,821,407 - 177,833,647 (+)NCBI
mRatBN7.22175,523,752 - 175,535,995 (+)NCBI
Rnor_6.02189,430,083 - 189,442,323 (+)NCBI
Celera2169,462,644 - 169,474,914 (+)NCBI
Sequence:
RefSeq Acc Id: NM_057208   ⟹   NP_476556
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,821,407 - 177,840,560 (+)NCBI
mRatBN7.22175,523,752 - 175,542,910 (+)NCBI
Rnor_6.02189,430,083 - 189,449,236 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
RGSC_v3.42182,303,994 - 182,324,994 (+)RGD
Celera2169,462,644 - 169,481,827 (+)NCBI
Sequence:
RefSeq Acc Id: NM_173111   ⟹   NP_775134
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,821,365 - 177,842,365 (+)NCBI
mRatBN7.22175,523,710 - 175,544,715 (+)NCBI
Rnor_6.02189,430,041 - 189,451,041 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
RGSC_v3.42182,303,994 - 182,324,994 (+)RGD
Celera2169,462,602 - 169,483,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232568   ⟹   XP_006232630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,842,661 (+)NCBI
mRatBN7.22175,517,207 - 175,545,014 (+)NCBI
Rnor_6.02189,423,535 - 189,451,340 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232569   ⟹   XP_006232631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,842,661 (+)NCBI
mRatBN7.22175,517,204 - 175,545,014 (+)NCBI
Rnor_6.02189,423,536 - 189,450,110 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232570   ⟹   XP_006232632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,833,647 (+)NCBI
mRatBN7.22175,517,206 - 175,537,734 (+)NCBI
Rnor_6.02189,423,536 - 189,443,459 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232572   ⟹   XP_006232634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,842,661 (+)NCBI
mRatBN7.22175,517,204 - 175,545,014 (+)NCBI
Rnor_6.02189,423,535 - 189,451,340 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232573   ⟹   XP_006232635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,842,661 (+)NCBI
mRatBN7.22175,517,199 - 175,545,014 (+)NCBI
Rnor_6.02189,423,534 - 189,450,110 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232576   ⟹   XP_006232638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,840,572 (+)NCBI
mRatBN7.22175,517,203 - 175,542,924 (+)NCBI
Rnor_6.02189,423,536 - 189,449,989 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232577   ⟹   XP_006232639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,840,572 (+)NCBI
mRatBN7.22175,517,198 - 175,542,924 (+)NCBI
Rnor_6.02189,423,534 - 189,449,989 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232581   ⟹   XP_006232643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,820,351 - 177,842,661 (+)NCBI
mRatBN7.22175,523,324 - 175,545,014 (+)NCBI
Rnor_6.02189,429,984 - 189,451,340 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232584   ⟹   XP_006232646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,820,319 - 177,840,572 (+)NCBI
mRatBN7.22175,522,643 - 175,542,924 (+)NCBI
Rnor_6.02189,429,980 - 189,449,989 (+)NCBI
Rnor_5.02208,856,598 - 208,884,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101595   ⟹   XP_038957523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,820,384 - 177,833,647 (+)NCBI
mRatBN7.22175,523,335 - 175,537,734 (+)NCBI
RefSeq Acc Id: XM_039101596   ⟹   XP_038957524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,820,365 - 177,842,661 (+)NCBI
mRatBN7.22175,523,326 - 175,545,014 (+)NCBI
RefSeq Acc Id: XM_039101597   ⟹   XP_038957525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,825,068 - 177,842,661 (+)NCBI
mRatBN7.22175,527,393 - 175,545,014 (+)NCBI
RefSeq Acc Id: XM_063281193   ⟹   XP_063137263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,833,647 (+)NCBI
RefSeq Acc Id: XM_063281194   ⟹   XP_063137264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,812,534 - 177,833,647 (+)NCBI
RefSeq Acc Id: XM_063281195   ⟹   XP_063137265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,820,272 - 177,833,647 (+)NCBI
RefSeq Acc Id: XM_063281196   ⟹   XP_063137266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,817,563 - 177,833,647 (+)NCBI
RefSeq Acc Id: XM_063281197   ⟹   XP_063137267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,820,257 - 177,842,661 (+)NCBI
RefSeq Acc Id: XM_063281198   ⟹   XP_063137268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,824,060 - 177,833,647 (+)NCBI
RefSeq Acc Id: XM_063281199   ⟹   XP_063137269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,825,046 - 177,833,647 (+)NCBI
RefSeq Acc Id: XM_063281200   ⟹   XP_063137270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,821,489 - 177,842,661 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001288214 (Get FASTA)   NCBI Sequence Viewer  
  NP_001288215 (Get FASTA)   NCBI Sequence Viewer  
  NP_476556 (Get FASTA)   NCBI Sequence Viewer  
  NP_775134 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232630 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232631 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232632 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232634 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232635 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232638 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232639 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232643 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232646 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957523 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957524 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957525 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137263 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137264 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137265 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137266 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137267 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137268 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137269 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137270 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA21721 (Get FASTA)   NCBI Sequence Viewer  
  AAA42263 (Get FASTA)   NCBI Sequence Viewer  
  AAA42264 (Get FASTA)   NCBI Sequence Viewer  
  AAB37701 (Get FASTA)   NCBI Sequence Viewer  
  AAC27290 (Get FASTA)   NCBI Sequence Viewer  
  AAC27291 (Get FASTA)   NCBI Sequence Viewer  
  AAC27292 (Get FASTA)   NCBI Sequence Viewer  
  CAA51382 (Get FASTA)   NCBI Sequence Viewer  
  EDM00587 (Get FASTA)   NCBI Sequence Viewer  
  EDM00588 (Get FASTA)   NCBI Sequence Viewer  
  EDM00589 (Get FASTA)   NCBI Sequence Viewer  
  EDM00590 (Get FASTA)   NCBI Sequence Viewer  
  EDM00591 (Get FASTA)   NCBI Sequence Viewer  
  EDM00592 (Get FASTA)   NCBI Sequence Viewer  
  EDM00593 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023567
  ENSRNOP00000023567.6
  ENSRNOP00000023605
  ENSRNOP00000023605.4
  ENSRNOP00000035561
  ENSRNOP00000035561.5
  ENSRNOP00000079275
  ENSRNOP00000079275.1
  ENSRNOP00000085183
  ENSRNOP00000085183.1
  ENSRNOP00000094091
  ENSRNOP00000094091.1
  ENSRNOP00000097306
  ENSRNOP00000097306.1
  ENSRNOP00055030448
  ENSRNOP00060042706
  ENSRNOP00065040566
GenBank Protein Q63610 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_775134   ⟸   NM_173111
- Peptide Label: isoform Tpm3.1cy
- UniProtKB: Q63610 (UniProtKB/Swiss-Prot),   Q63600 (UniProtKB/Swiss-Prot),   Q63599 (UniProtKB/Swiss-Prot),   Q63601 (UniProtKB/Swiss-Prot),   A6J6J6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_476556   ⟸   NM_057208
- Peptide Label: isoform Tpm3.4cy
- UniProtKB: A6J6J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232639   ⟸   XM_006232577
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006232635   ⟸   XM_006232573
- Peptide Label: isoform X7
- UniProtKB: A0A140TAF0 (UniProtKB/TrEMBL),   A6J6J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232631   ⟸   XM_006232569
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006232638   ⟸   XM_006232576
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006232632   ⟸   XM_006232570
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006232630   ⟸   XM_006232568
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A144 (UniProtKB/TrEMBL),   A6J6J4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232634   ⟸   XM_006232572
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006232646   ⟸   XM_006232584
- Peptide Label: isoform X16
- UniProtKB: A0A8L2QDD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232643   ⟸   XM_006232581
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: NP_001288214   ⟸   NM_001301285
- Peptide Label: isoform Tpm3.12st
- Sequence:
RefSeq Acc Id: NP_001288215   ⟸   NM_001301286
- Peptide Label: isoform Tpm3.3cy
- UniProtKB: A6J6K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000023605   ⟸   ENSRNOT00000023605
RefSeq Acc Id: ENSRNOP00000023567   ⟸   ENSRNOT00000023567
RefSeq Acc Id: ENSRNOP00000035561   ⟸   ENSRNOT00000029076
RefSeq Acc Id: XP_038957524   ⟸   XM_039101596
- Peptide Label: isoform X13
- UniProtKB: A0A8L2QDD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957523   ⟸   XM_039101595
- Peptide Label: isoform X12
- UniProtKB: A0A8L2QDD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957525   ⟸   XM_039101597
- Peptide Label: isoform X18
- UniProtKB: A0A8I6G322 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000097306   ⟸   ENSRNOT00000101991
RefSeq Acc Id: ENSRNOP00000085183   ⟸   ENSRNOT00000114156
RefSeq Acc Id: ENSRNOP00000079275   ⟸   ENSRNOT00000112248
RefSeq Acc Id: ENSRNOP00000094091   ⟸   ENSRNOT00000101614
RefSeq Acc Id: XP_063137263   ⟸   XM_063281193
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137264   ⟸   XM_063281194
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063137266   ⟸   XM_063281196
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063137267   ⟸   XM_063281197
- Peptide Label: isoform X15
- UniProtKB: A6J6K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137265   ⟸   XM_063281195
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063137270   ⟸   XM_063281200
- Peptide Label: isoform X20
RefSeq Acc Id: XP_063137268   ⟸   XM_063281198
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063137269   ⟸   XM_063281199
- Peptide Label: isoform X19

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63610-F1-model_v2 AlphaFold Q63610 1-248 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691490
Promoter ID:EPDNEW_R2015
Type:single initiation site
Name:Tpm3_2
Description:tropomyosin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2016  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02189,423,559 - 189,423,619EPDNEW
RGD ID:13691491
Promoter ID:EPDNEW_R2016
Type:initiation region
Name:Tpm3_1
Description:tropomyosin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2015  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02189,430,033 - 189,430,093EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621546 AgrOrtholog
BioCyc Gene G2FUF-52369 BioCyc
Ensembl Genes ENSRNOG00000017441 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055021757 UniProtKB/Swiss-Prot
  ENSRNOG00060029359 UniProtKB/Swiss-Prot
  ENSRNOG00065028576 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023567.9 UniProtKB/TrEMBL
  ENSRNOT00000023605.8 UniProtKB/TrEMBL
  ENSRNOT00000029076 ENTREZGENE
  ENSRNOT00000029076.6 UniProtKB/TrEMBL
  ENSRNOT00000101614.1 UniProtKB/TrEMBL
  ENSRNOT00000101991 ENTREZGENE
  ENSRNOT00000101991.1 UniProtKB/TrEMBL
  ENSRNOT00000112248.1 UniProtKB/TrEMBL
  ENSRNOT00000114156.1 UniProtKB/TrEMBL
  ENSRNOT00055037364 UniProtKB/Swiss-Prot
  ENSRNOT00060051339 UniProtKB/Swiss-Prot
  ENSRNOT00065049440 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  1.20.5.370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Tropomyosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XRCC4-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117557 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 117557 ENTREZGENE
PANTHER TROPOMYOSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TROPOMYOSIN 3, RELATED SEQUENCE 7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TROPOMYOSIN ALPHA-3 CHAIN UniProtKB/TrEMBL
Pfam Tropomyosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tpm3 PhenoGen
PRINTS TROPOMYOSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TROPOMYOSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017441 RatGTEx
  ENSRNOG00055021757 RatGTEx
  ENSRNOG00060029359 RatGTEx
  ENSRNOG00065028576 RatGTEx
Superfamily-SCOP Tropomyosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140TAF0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A144 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B5K9_RAT UniProtKB/TrEMBL
  A0A8I6G322 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QDD2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QDD9 ENTREZGENE, UniProtKB/TrEMBL
  A6J6J4 ENTREZGENE, UniProtKB/TrEMBL
  A6J6J5 ENTREZGENE, UniProtKB/TrEMBL
  A6J6J6 ENTREZGENE, UniProtKB/TrEMBL
  A6J6J8 ENTREZGENE, UniProtKB/TrEMBL
  A6J6K0 ENTREZGENE, UniProtKB/TrEMBL
  Q63599 ENTREZGENE
  Q63600 ENTREZGENE
  Q63601 ENTREZGENE
  Q63610 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q63599 UniProtKB/Swiss-Prot
  Q63600 UniProtKB/Swiss-Prot
  Q63601 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-27 Tpm3  tropomyosin 3  Tpm3  tropomyosin 3, gamma  Name changed 629549 APPROVED
2005-07-08 Tpm3  tropomyosin 3, gamma      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tpm3  tropomyosin 3, gamma      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression more than 10 isoforms in brain 634228