Gdf10 (growth differentiation factor 10) - Rat Genome Database

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Gene: Gdf10 (growth differentiation factor 10) Rattus norvegicus
Analyze
Symbol: Gdf10
Name: growth differentiation factor 10
RGD ID: 621512
Description: Predicted to enable cytokine activity. Involved in several processes, including positive regulation of osteoblast differentiation; response to kainic acid; and response to transforming growth factor beta. Located in extracellular space. Orthologous to human GDF10 (growth differentiation factor 10); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BIP; BMP-3b; bone morphogenetic protein 3B; bone-inducing protein; GDF-10; growth/differentiation factor 10; prepro bone inducing protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,243,434 - 9,256,788 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl169,243,317 - 9,256,794 (+)EnsemblGRCr8
mRatBN7.2169,237,182 - 9,250,537 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,237,261 - 9,249,343 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx169,256,689 - 9,268,770 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01610,401,395 - 10,413,477 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0169,251,785 - 9,263,853 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01610,250,508 - 10,262,383 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,250,404 - 10,263,150 (+)Ensemblrn6Rnor6.0
Rnor_5.0168,571,370 - 8,583,245 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4169,558,781 - 9,570,656 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera165,961,266 - 5,973,147 (-)NCBICelera
RGSC_v3.1169,558,727 - 9,570,654 (+)NCBI
Cytogenetic Map16p16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
astemizole  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
glycerol 2-phosphate  (EXP)
inulin  (ISO)
L-ascorbic acid  (EXP)
L-methionine  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxyacetic acid  (EXP)
methylmercury chloride  (EXP)
Monobutylphthalate  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
oxaliplatin  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
XL147  (ISO)
zaragozic acid A  (EXP,ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Assessment of gene expression profiles in peripheral occlusive arterial disease. Bubenek S, etal., Can J Cardiol. 2012 Nov-Dec;28(6):712-20. doi: 10.1016/j.cjca.2012.03.013. Epub 2012 Jun 19.
2. Relationship of bone morphogenetic protein expression during osteoblast differentiation to wild type p53. Chandar N, etal., J Orthop Res. 2005 Nov;23(6):1345-53. Epub 2005 Jul 1.
3. The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle. Erickson GF and Shimasaki S, Reprod Biol Endocrinol. 2003 Feb 5;1:9.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Bone morphogenetic protein-3b (BMP-3b) gene expression is correlated with differentiation in rat calvarial osteoblasts. Hino J, etal., Biochem Biophys Res Commun. 1999 Mar 16;256(2):419-24.
7. Over expression of bone morphogenetic protein-3b (BMP-3b) using an adenoviral vector promote the osteoblastic differentiation in C2C12 cells and augment the bone formation induced by bone morphogenetic protein-2 (BMP-2) in rats. Kaihara S, etal., Life Sci. 2003 Feb 28;72(15):1683-93.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Antisense oligonucleotide for tissue factor inhibits hepatic ischemic reperfusion injury. Nakamura K, etal., Biochem Biophys Res Commun 2002 Sep 27;297(3):433-41.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain. Sokka AL, etal., J Neurosci. 2007 Jan 24;27(4):901-8.
15. Identification of rat bone morphogenetic protein-3b (BMP-3b), a new member of BMP-3. Takao M, etal., Biochem Biophys Res Commun 1996 Feb 15;219(2):656-62.
Additional References at PubMed
PMID:20096814   PMID:21712809   PMID:26811051   PMID:27068509   PMID:28394782   PMID:36714584  


Genomics

Comparative Map Data
Gdf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,243,434 - 9,256,788 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl169,243,317 - 9,256,794 (+)EnsemblGRCr8
mRatBN7.2169,237,182 - 9,250,537 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,237,261 - 9,249,343 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx169,256,689 - 9,268,770 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01610,401,395 - 10,413,477 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0169,251,785 - 9,263,853 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01610,250,508 - 10,262,383 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,250,404 - 10,263,150 (+)Ensemblrn6Rnor6.0
Rnor_5.0168,571,370 - 8,583,245 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4169,558,781 - 9,570,656 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera165,961,266 - 5,973,147 (-)NCBICelera
RGSC_v3.1169,558,727 - 9,570,654 (+)NCBI
Cytogenetic Map16p16NCBI
GDF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381047,300,197 - 47,313,577 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1047,300,171 - 47,313,577 (+)Ensemblhg38GRCh38
GRCh371048,425,785 - 48,439,165 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361048,045,795 - 48,059,172 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341048,045,794 - 48,059,172NCBI
Celera1044,850,007 - 44,863,384 (-)NCBICelera
Cytogenetic Map10q11.22NCBI
HuRef1043,178,553 - 43,191,903 (-)NCBIHuRef
CHM1_11048,590,851 - 48,604,204 (-)NCBICHM1_1
T2T-CHM13v2.01048,191,293 - 48,204,673 (+)NCBIT2T-CHM13v2.0
Gdf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,645,544 - 33,658,471 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,645,544 - 33,659,940 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381433,923,587 - 33,936,514 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,923,587 - 33,937,983 (+)Ensemblmm10GRCm38
MGSCv371434,736,773 - 34,748,471 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361432,752,679 - 32,764,377 (+)NCBIMGSCv36mm8
Celera1430,189,682 - 30,201,380 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.8NCBI
Gdf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555562,185,121 - 2,196,502 (+)Ensembl
ChiLan1.0NW_0049555562,185,121 - 2,195,150 (+)NCBIChiLan1.0ChiLan1.0
GDF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2859,997,778 - 60,011,111 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,003,095 - 60,016,428 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01046,498,600 - 46,511,933 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GDF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1435,008,204 - 35,017,476 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl435,008,983 - 35,018,166 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha434,972,559 - 34,981,749 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0435,368,659 - 35,377,901 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl435,368,660 - 35,378,771 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1435,200,361 - 35,209,442 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0435,381,596 - 35,390,831 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0435,889,219 - 35,898,460 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gdf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721381,283,121 - 81,297,318 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365547,292,767 - 7,307,009 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365547,292,805 - 7,307,001 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GDF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1488,522,948 - 88,534,709 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11488,522,956 - 88,534,719 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21496,148,673 - 96,160,426 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GDF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1944,066,979 - 44,080,319 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl944,067,469 - 44,079,522 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660483,837,123 - 3,850,490 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gdf10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1139,693,479 - 9,705,477 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gdf10
117 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16423421216278352Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16423421216278352Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421216061395Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16423433317730812Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH128730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2169,249,015 - 9,249,196 (+)MAPPERmRatBN7.2
Rnor_6.01610,262,056 - 10,262,236NCBIRnor6.0
Rnor_5.0168,582,918 - 8,583,098UniSTSRnor5.0
RGSC_v3.4169,570,329 - 9,570,509UniSTSRGSC3.4
Celera165,961,413 - 5,961,593UniSTS
RH 3.4 Map1692.8UniSTS
Cytogenetic Map16p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 12 65 137 91 90 59 53 59 6 300 151 11 109 70 91 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000081183   ⟹   ENSRNOP00000069581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl169,243,317 - 9,256,794 (+)Ensembl
mRatBN7.2 Ensembl169,237,261 - 9,249,343 (+)Ensembl
Rnor_6.0 Ensembl1610,250,461 - 10,263,150 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087037   ⟹   ENSRNOP00000075201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1610,250,404 - 10,262,383 (+)Ensembl
RefSeq Acc Id: NM_024375   ⟹   NP_077351
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8169,243,512 - 9,255,594 (+)NCBI
mRatBN7.2169,237,261 - 9,249,343 (+)NCBI
Rnor_6.01610,250,508 - 10,262,383 (+)NCBI
Rnor_5.0168,571,370 - 8,583,245 (+)NCBI
RGSC_v3.4169,558,781 - 9,570,656 (+)RGD
Celera165,961,266 - 5,973,147 (-)RGD
Sequence:
RefSeq Acc Id: XM_039094852   ⟹   XP_038950780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8169,243,434 - 9,256,788 (+)NCBI
mRatBN7.2169,237,182 - 9,250,537 (+)NCBI
Protein Sequences
Protein RefSeqs NP_077351 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950780 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA08454 (Get FASTA)   NCBI Sequence Viewer  
  EDL88894 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069581
  ENSRNOP00000069581.2
GenBank Protein P55108 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077351   ⟸   NM_024375
- Peptide Label: precursor
- UniProtKB: P55108 (UniProtKB/Swiss-Prot),   A6KFT7 (UniProtKB/TrEMBL),   A0A0G2JVQ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075201   ⟸   ENSRNOT00000087037
Ensembl Acc Id: ENSRNOP00000069581   ⟸   ENSRNOT00000081183
RefSeq Acc Id: XP_038950780   ⟸   XM_039094852
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVQ8 (UniProtKB/TrEMBL)
Protein Domains
TGF-beta family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55108-F1-model_v2 AlphaFold P55108 1-476 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621512 AgrOrtholog
BioCyc Gene G2FUF-12084 BioCyc
Ensembl Genes ENSRNOG00000051993 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000081183 ENTREZGENE
  ENSRNOT00000081183.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot
InterPro BMP3/BMP3B UniProtKB/Swiss-Prot
  Cystine-knot_cytokine UniProtKB/Swiss-Prot
  TGF-b_C UniProtKB/Swiss-Prot
  TGF-beta-rel UniProtKB/Swiss-Prot
  TGFb_CS UniProtKB/Swiss-Prot
KEGG Report rno:79216 UniProtKB/Swiss-Prot
NCBI Gene 79216 ENTREZGENE
PANTHER GROWTH/DIFFERENTIATION FACTOR 10 UniProtKB/Swiss-Prot
  PTHR11848 UniProtKB/Swiss-Prot
Pfam TGF_beta UniProtKB/Swiss-Prot
PharmGKB GDF10 RGD
PhenoGen Gdf10 PhenoGen
PIRSF BMP3/GDF10 UniProtKB/Swiss-Prot
PROSITE TGF_BETA_1 UniProtKB/Swiss-Prot
  TGF_BETA_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000051993 RatGTEx
SMART TGFB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot
UniProt A0A0G2JVQ8 ENTREZGENE, UniProtKB/TrEMBL
  A6KFT7 ENTREZGENE, UniProtKB/TrEMBL
  GDF10_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Gdf10  growth differentiation factor 10    prepro bone inducing protein  Name updated 1299863 APPROVED
2002-08-07 Gdf10  prepro bone inducing protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in costa, costicartilage, femur, calvaria, trachea, aorta and brain 631791
gene_product member of bone morphogenetic protein-3 (BMP-3) 631791