Ngb (neuroglobin) - Rat Genome Database

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Gene: Ngb (neuroglobin) Rattus norvegicus
Analyze
Symbol: Ngb
Name: neuroglobin
RGD ID: 621461
Description: Predicted to enable several functions, including GDP-dissociation inhibitor activity; oxygen binding activity; and oxygen carrier activity. Involved in several processes, including cellular response to hydrogen peroxide; response to hypoxia; and response to iron ion. Located in perikaryon. Used to study transient cerebral ischemia. Biomarker of Alzheimer's disease; encephalitis; retinal ischemia; and transient cerebral ischemia. Orthologous to human NGB (neuroglobin); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; barium sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Glnh; globin h; nitrite reductase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,475,332 - 112,480,786 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6112,475,332 - 112,480,786 (-)EnsemblGRCr8
mRatBN7.26106,744,378 - 106,749,830 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6106,744,378 - 106,749,830 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6106,912,130 - 106,917,574 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06107,210,967 - 107,216,411 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06106,580,643 - 106,586,085 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06111,126,259 - 111,131,699 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,126,261 - 111,132,320 (-)Ensemblrn6Rnor6.0
Rnor_5.06120,412,241 - 120,417,508 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46111,231,188 - 111,236,255 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6104,565,839 - 104,571,131 (-)NCBICelera
RGSC_v3.16111,234,718 - 111,239,786 (-)NCBI
Cytogenetic Map6q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
mitochondrial matrix  (IEA,ISO)
perikaryon  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Does neuroglobin protect neurons from ischemic insult? A quantitative investigation of neuroglobin expression following transient MCAo in spontaneously hypertensive rats. Hundahl C, etal., Brain Res. 2006 Apr 26;1085(1):19-27. Epub 2006 May 2.
3. Neuroglobin in the rat brain (II): co-localisation with neurotransmitters. Hundahl CA, etal., Neuroendocrinology. 2008;88(3):183-98. doi: 10.1159/000135617. Epub 2008 May 29.
4. Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity. Lechauve C, etal., Biochim Biophys Acta. 2012 Dec;1823(12):2261-73. doi: 10.1016/j.bbamcr.2012.09.009. Epub 2012 Oct 2.
5. Neuroglobin promotes neurite outgrowth via differential binding to PTEN and Akt. Li L, etal., Mol Neurobiol. 2014 Feb;49(1):149-62. doi: 10.1007/s12035-013-8506-7. Epub 2013 Aug 1.
6. Hypoxia differentially regulates the expression of neuroglobin and cytoglobin in rat brain. Li RC, etal., Brain Res. 2006 Jun 22;1096(1):173-9. Epub 2006 Jun 5.
7. Neuroglobin protects PC12 cells against oxidative stress. Li RC, etal., Brain Res. 2008 Jan 23;1190:159-66. Epub 2007 Nov 22.
8. Expression and cell distribution of neuroglobin in the brain tissue after experimental subarachnoid hemorrhage in rats: a pilot study. Li WD, etal., Cell Mol Neurobiol. 2014 Mar;34(2):247-55. doi: 10.1007/s10571-013-0008-7. Epub 2013 Nov 27.
9. [Expression of neuroglobin in rats with brain injury induced by LPS]. Liu C, etal., Zhonghua Shao Shang Za Zhi. 2009 Jun;25(3):222-6.
10. Sleep deprivation reduces neuroglobin immunoreactivity in the rat brain. Melgarejo-Gutierrez M, etal., Neuroreport. 2013 Feb 13;24(3):120-5. doi: 10.1097/WNR.0b013e32835d4b74.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Resonance micro-Raman investigations of the rat medial preoptic nucleus: effects of a low-iron diet on the neuroglobin content. Ramser K, etal., Appl Spectrosc. 2012 Dec;66(12):1454-60. doi: 10.1366/12-06670.
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Neuroprotective effects of neuroglobin after mechanical injury. Shang A, etal., Neurol Sci. 2012 Jun;33(3):551-8. doi: 10.1007/s10072-011-0772-4. Epub 2011 Sep 14.
19. Expression of neuroglobin in ocular hypertension induced acute hypoxic-ischemic retinal injury in rats. Shi SY, etal., Int J Ophthalmol. 2011;4(4):393-5. doi: 10.3980/j.issn.2222-3959.2011.04.14. Epub 2011 Aug 18.
20. Effect of aging on neuroglobin expression in rodent brain. Sun Y, etal., Neurobiol Aging. 2005 Feb;26(2):275-8.
21. Neuroglobin protects the brain from experimental stroke in vivo. Sun Y, etal., Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3497-500. Epub 2003 Mar 5.
22. [Involvement of cerebral neuroglobin in electroacupuncture preconditioning-induced protection effect in cerebral ischemia-reperfusion rats]. Xie YN, etal., Zhen Ci Yan Jiu. 2012 Oct;37(5):380-4.
23. Ibuprofen and lipoic acid conjugate neuroprotective activity is mediated by Ngb/Akt intracellular signaling pathway in Alzheimer's disease rat model. Zara S, etal., Gerontology. 2013;59(3):250-60. doi: 10.1159/000346445. Epub 2013 Feb 20.
24. Full-length cDNA cloning of human neuroglobin and tissue expression of rat neuroglobin. Zhang C, etal., Biochem Biophys Res Commun 2002 Feb 8;290(5):1411-9.
25. [Coding region cDNA sequence cloning of rat neuroglobin gene, its polymorphism feature and tissue expression profile analysis] Zhang CG, etal., Yi Chuan Xue Bao 2001 Nov;28(11):997-1001.
Additional References at PubMed
PMID:8889548   PMID:11029004   PMID:15193759   PMID:16683692   PMID:16796995   PMID:17560688   PMID:17576199   PMID:18451642   PMID:19327369   PMID:19536481   PMID:20187147   PMID:20211612  
PMID:20230802   PMID:20476562   PMID:21054965   PMID:21767627   PMID:22009023   PMID:22472608   PMID:22664218   PMID:22887765   PMID:23180278   PMID:23639750   PMID:23673310   PMID:24145836  
PMID:24491879   PMID:24747803   PMID:25557405   PMID:25636685   PMID:26400308   PMID:26646387   PMID:26983282   PMID:28359933   PMID:28829495   PMID:29802248   PMID:32205448   PMID:35818200  
PMID:36884214  


Genomics

Comparative Map Data
Ngb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,475,332 - 112,480,786 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6112,475,332 - 112,480,786 (-)EnsemblGRCr8
mRatBN7.26106,744,378 - 106,749,830 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6106,744,378 - 106,749,830 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6106,912,130 - 106,917,574 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06107,210,967 - 107,216,411 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06106,580,643 - 106,586,085 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06111,126,259 - 111,131,699 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,126,261 - 111,132,320 (-)Ensemblrn6Rnor6.0
Rnor_5.06120,412,241 - 120,417,508 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46111,231,188 - 111,236,255 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6104,565,839 - 104,571,131 (-)NCBICelera
RGSC_v3.16111,234,718 - 111,239,786 (-)NCBI
Cytogenetic Map6q31NCBI
NGB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381477,265,483 - 77,271,206 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1477,265,483 - 77,271,206 (-)Ensemblhg38GRCh38
GRCh371477,731,826 - 77,737,549 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361476,801,587 - 76,807,408 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341476,801,580 - 76,807,408NCBI
Celera1457,770,473 - 57,776,215 (-)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1457,898,325 - 57,904,062 (-)NCBIHuRef
CHM1_11477,671,361 - 77,677,104 (-)NCBICHM1_1
T2T-CHM13v2.01471,474,790 - 71,480,551 (-)NCBIT2T-CHM13v2.0
Ngb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391287,144,305 - 87,149,313 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1287,144,305 - 87,149,313 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381287,097,531 - 87,102,539 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1287,097,531 - 87,102,539 (-)Ensemblmm10GRCm38
MGSCv371288,438,481 - 88,443,489 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361287,986,634 - 87,991,642 (-)NCBIMGSCv36mm8
Celera1288,562,002 - 88,567,162 (-)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1241.29NCBI
Ngb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554381,170,888 - 1,175,978 (-)Ensembl
ChiLan1.0NW_0049554381,170,888 - 1,175,978 (-)NCBIChiLan1.0ChiLan1.0
NGB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21578,349,121 - 78,354,740 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11477,565,625 - 77,571,242 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01457,818,491 - 57,824,196 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11477,020,274 - 77,025,983 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1477,020,274 - 77,025,983 (-)EnsemblpanPan2panpan1.1
NGB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1850,081,960 - 50,086,071 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl850,081,960 - 50,085,435 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha849,769,803 - 49,773,792 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0850,314,590 - 50,325,270 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl850,315,118 - 50,319,630 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1849,978,294 - 49,982,287 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0850,001,322 - 50,005,311 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0850,399,520 - 50,403,524 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ngb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864025,969,328 - 25,974,879 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364886,095,016 - 6,098,543 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364886,094,089 - 6,098,876 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NGB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7100,340,940 - 100,346,438 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17100,341,974 - 100,346,263 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27106,610,972 - 106,615,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NGB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12454,510,877 - 54,518,535 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2454,511,924 - 54,516,210 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605342,711,096 - 42,716,772 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ngb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473424,640,181 - 24,647,243 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473424,640,389 - 24,645,041 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ngb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17101,198,563 - 101,203,698 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ngb
54 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:480
Count of miRNA genes:229
Interacting mature miRNAs:276
Transcripts:ENSRNOT00000016057
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)699708426112483760Rat

Markers in Region
RH143985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26106,744,474 - 106,744,593 (+)MAPPERmRatBN7.2
Rnor_6.06111,126,356 - 111,126,474NCBIRnor6.0
Rnor_5.06120,412,338 - 120,412,456UniSTSRnor5.0
RGSC_v3.46111,231,284 - 111,231,402UniSTSRGSC3.4
Celera6104,565,936 - 104,566,054UniSTS
RH 3.4 Map6743.6UniSTS
Cytogenetic Map6q31UniSTS
NGB  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26106,746,842 - 106,747,639 (+)MAPPERmRatBN7.2
Rnor_6.06111,128,724 - 111,129,520NCBIRnor6.0
Rnor_5.06120,414,706 - 120,415,502UniSTSRnor5.0
RGSC_v3.46111,233,652 - 111,234,448UniSTSRGSC3.4
Celera6104,568,304 - 104,569,100UniSTS
Cytogenetic Map6q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 10 63 148 66 65 34 76 34 6 292 167 5 130 73 89 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000016057   ⟹   ENSRNOP00000016057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6112,475,332 - 112,480,786 (-)Ensembl
mRatBN7.2 Ensembl6106,744,378 - 106,749,830 (-)Ensembl
Rnor_6.0 Ensembl6111,126,261 - 111,132,320 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081727   ⟹   ENSRNOP00000073109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6111,127,246 - 111,131,271 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085112   ⟹   ENSRNOP00000072994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6111,127,701 - 111,128,735 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108396   ⟹   ENSRNOP00000078847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6112,477,879 - 112,480,786 (-)Ensembl
mRatBN7.2 Ensembl6106,746,925 - 106,749,830 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000141642   ⟹   ENSRNOP00000109564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6112,475,363 - 112,480,786 (-)Ensembl
RefSeq Acc Id: NM_033359   ⟹   NP_203523
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86112,475,332 - 112,480,786 (-)NCBI
mRatBN7.26106,744,378 - 106,749,830 (-)NCBI
Rnor_6.06111,126,259 - 111,131,699 (-)NCBI
Rnor_5.06120,412,241 - 120,417,508 (-)NCBI
RGSC_v3.46111,231,188 - 111,236,255 (-)RGD
Celera6104,565,839 - 104,571,131 (-)NCBI
Sequence:
RefSeq Acc Id: NP_203523   ⟸   NM_033359
- UniProtKB: Q99N62 (UniProtKB/Swiss-Prot),   Q8VH38 (UniProtKB/Swiss-Prot),   Q99JA8 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016057   ⟸   ENSRNOT00000016057
Ensembl Acc Id: ENSRNOP00000072994   ⟸   ENSRNOT00000085112
Ensembl Acc Id: ENSRNOP00000073109   ⟸   ENSRNOT00000081727
Ensembl Acc Id: ENSRNOP00000078847   ⟸   ENSRNOT00000108396
Ensembl Acc Id: ENSRNOP00000109564   ⟸   ENSRNOT00000141642
Protein Domains
GLOBIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99JA8-F1-model_v2 AlphaFold Q99JA8 1-151 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621461 AgrOrtholog
BioCyc Gene G2FUF-36728 BioCyc
Ensembl Genes ENSRNOG00000011719 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000016057 ENTREZGENE
Gene3D-CATH 1.10.490.10 UniProtKB/Swiss-Prot
InterPro Globin UniProtKB/Swiss-Prot
  Globin-like_OT UniProtKB/Swiss-Prot
  Globin-like_sf UniProtKB/Swiss-Prot
  Globin/Proto UniProtKB/Swiss-Prot
KEGG Report rno:85382 UniProtKB/Swiss-Prot
NCBI Gene 85382 ENTREZGENE
PANTHER BLR2807 PROTEIN UniProtKB/Swiss-Prot
  NEUROGLOBIN UniProtKB/Swiss-Prot
Pfam Globin UniProtKB/Swiss-Prot
PhenoGen Ngb PhenoGen
PROSITE GLOBIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011719 RatGTEx
Superfamily-SCOP SSF46458 UniProtKB/Swiss-Prot
UniProt A0A0G2JSL1_RAT UniProtKB/TrEMBL
  A0A8I5ZM27_RAT UniProtKB/TrEMBL
  A0ABK0M448_RAT UniProtKB/TrEMBL
  A6JE79_RAT UniProtKB/TrEMBL
  A6JE80_RAT UniProtKB/TrEMBL
  NGB_RAT UniProtKB/Swiss-Prot
  Q8VH38 ENTREZGENE
  Q99JA8 ENTREZGENE
  Q99N62 ENTREZGENE
UniProt Secondary Q8VH38 UniProtKB/Swiss-Prot
  Q99N62 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ngb  neuroglobin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ngb  neuroglobin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in cerebral cortex, hippocampus, thalamus, hypothalamus, olfactory bulb, and cerebellum 625434
gene_protein 151 amino acid protein 729218