Kcnk9 (potassium two pore domain channel subfamily K member 9) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Kcnk9 (potassium two pore domain channel subfamily K member 9) Rattus norvegicus
Analyze
Symbol: Kcnk9
Name: potassium two pore domain channel subfamily K member 9
RGD ID: 621451
Description: Enables protein heterodimerization activity. Involved in potassium ion transport. Located in synaptic vesicle. Human ortholog(s) of this gene implicated in Birk-Barel syndrome. Orthologous to human KCNK9 (potassium two pore domain channel subfamily K member 9); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; barium(0).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acid-sensitive potassium channel protein TASK-3; potassium channel subfamily K member 9; potassium channel subfamily K member 9 (Task-3); potassium channel, subfamily K, member 9; potassium channel, subfamily K, member 9 (Task-3); potassium channel, two pore domain subfamily K, member 9; Task-3; Task3; TWIK-related acid-sensitive K(+) channel 3; two pore K(+) channel KT3.2; two pore potassium channel KT3.2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87106,316,783 - 106,362,452 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7106,326,684 - 106,361,921 (-)EnsemblGRCr8
mRatBN7.27104,429,186 - 104,473,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7104,437,934 - 104,473,175 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7106,175,328 - 106,209,602 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07108,396,911 - 108,431,185 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07108,344,952 - 108,379,226 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07113,894,918 - 113,938,397 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7113,903,557 - 113,937,941 (-)Ensemblrn6Rnor6.0
Rnor_5.07113,833,880 - 113,875,792 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47110,232,743 - 110,267,546 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7100,852,648 - 100,887,465 (-)NCBICelera
RGSC_v3.17110,266,630 - 110,301,866 (-)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Motoneurons express heteromeric TWIK-related acid-sensitive K+ (TASK) channels containing TASK-1 (KCNK3) and TASK-3 (KCNK9) subunits. Berg AP, etal., J Neurosci. 2004 Jul 28;24(30):6693-702.
2. Immunolocalization of TASK-3 (KCNK9) to a subset of cortical neurons in the rat CNS. Callahan R, etal., Biochem Biophys Res Commun. 2004 Jun 25;319(2):525-30.
3. TASK-3 dominates the background potassium conductance in rat adrenal glomerulosa cells. Czirjak G and Enyedi P, Mol Endocrinol 2002 Mar;16(3):621-9.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Characterization of four types of background potassium channels in rat cerebellar granule neurons. Han J, etal., J Physiol 2002 Jul 15;542(Pt 2):431-44.
7. Developmental expression of two-pore domain K+ channels, TASK-1 and TREK-1, in the rat cochlea. Kanjhan R, etal., Neuroreport. 2004 Mar 1;15(3):437-41.
8. TASK-3, a new member of the tandem pore K(+) channel family. Kim Y, etal., J Biol Chem 2000 Mar 31;275(13):9340-7.
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Cardiorespiratory neurons of the rat ventrolateral medulla contain TASK-1 and TASK-3 channel mRNA. Washburn CP, etal., Respir Physiol Neurobiol 2003 Oct 16;138(1):19-35.
15. TASK-1, TASK-2, TASK-3 and TRAAK immunoreactivities in the rat carotid body. Yamamoto Y, etal., Brain Res 2002 Sep 20;950(1-2):304-7.
Additional References at PubMed
PMID:11042359   PMID:11431495   PMID:11749039   PMID:12783883   PMID:14574589   PMID:15197476   PMID:15781965   PMID:16513667   PMID:16760342   PMID:16864570   PMID:16925981   PMID:17167057  
PMID:18375952   PMID:18691333   PMID:20019330   PMID:20351106   PMID:21082237   PMID:21357689   PMID:21710317   PMID:22011781   PMID:22017174   PMID:23219908   PMID:24077856   PMID:25405940  
PMID:25634809   PMID:31472119  


Genomics

Comparative Map Data
Kcnk9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87106,316,783 - 106,362,452 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7106,326,684 - 106,361,921 (-)EnsemblGRCr8
mRatBN7.27104,429,186 - 104,473,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7104,437,934 - 104,473,175 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7106,175,328 - 106,209,602 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07108,396,911 - 108,431,185 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07108,344,952 - 108,379,226 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07113,894,918 - 113,938,397 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7113,903,557 - 113,937,941 (-)Ensemblrn6Rnor6.0
Rnor_5.07113,833,880 - 113,875,792 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47110,232,743 - 110,267,546 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7100,852,648 - 100,887,465 (-)NCBICelera
RGSC_v3.17110,266,630 - 110,301,866 (-)NCBI
Cytogenetic Map7q34NCBI
KCNK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388139,600,838 - 139,703,123 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8139,600,838 - 139,704,109 (-)Ensemblhg38GRCh38
GRCh378140,613,081 - 140,715,366 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368140,693,986 - 140,784,481 (-)NCBIBuild 36Build 36hg18NCBI36
Build 348140,693,985 - 140,784,481NCBI
Celera8136,793,017 - 136,883,509 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8135,936,234 - 135,960,886 (-)NCBIHuRef
CHM1_18140,665,099 - 140,755,502 (-)NCBICHM1_1
T2T-CHM13v2.08140,720,918 - 140,823,244 (-)NCBIT2T-CHM13v2.0
Kcnk9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391572,373,722 - 72,422,415 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1572,372,938 - 72,418,189 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381572,501,873 - 72,548,614 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1572,501,089 - 72,546,340 (-)Ensemblmm10GRCm38
MGSCv371572,342,549 - 72,376,709 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361572,339,375 - 72,373,535 (-)NCBIMGSCv36mm8
Celera1574,012,672 - 74,045,135 (-)NCBICelera
Cytogenetic Map15D3NCBI
Kcnk9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546113,412,436 - 13,476,803 (-)Ensembl
ChiLan1.0NW_00495546113,406,969 - 13,476,720 (-)NCBIChiLan1.0ChiLan1.0
KCNK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27156,994,384 - 157,099,937 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18132,522,844 - 132,628,147 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08136,270,521 - 136,376,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18139,366,227 - 139,471,051 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8139,366,227 - 139,472,484 (-)EnsemblpanPan2panpan1.1
KCNK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11334,461,430 - 34,475,070 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1334,473,488 - 34,474,866 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1334,390,607 - 34,467,593 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01334,854,737 - 34,931,927 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1334,856,016 - 34,933,171 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11334,578,072 - 34,655,127 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01334,667,586 - 34,744,661 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01335,088,113 - 35,164,345 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kcnk9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053033,834,735 - 3,868,314 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647011,260,828 - 11,296,854 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647011,260,835 - 11,294,391 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl43,561,939 - 3,641,315 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.143,562,086 - 3,643,248 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.243,047,161 - 3,123,869 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNK9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18133,872,599 - 133,964,259 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8133,869,524 - 133,964,415 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660395,961,097 - 6,065,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnk9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473516,683,004 - 16,754,158 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473516,683,099 - 16,744,648 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Kcnk9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11245,301,291 - 245,343,362 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kcnk9
213 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:112
Interacting mature miRNAs:128
Transcripts:ENSRNOT00000012408
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
1331723Bw25Body weight QTL 253.348body mass (VT:0001259)body weight (CMO:0000012)796700404111672180Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 5 12 123 47 38 18 16 18 5 97 44 104 21 49 20 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000012408   ⟹   ENSRNOP00000012408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7106,326,684 - 106,361,921 (-)Ensembl
mRatBN7.2 Ensembl7104,437,934 - 104,473,175 (-)Ensembl
Rnor_6.0 Ensembl7113,903,557 - 113,937,941 (-)Ensembl
RefSeq Acc Id: NM_053405   ⟹   NP_445857
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87106,327,026 - 106,361,831 (-)NCBI
mRatBN7.27104,438,276 - 104,473,085 (-)NCBI
Rnor_6.07113,903,756 - 113,937,655 (-)NCBI
Rnor_5.07113,833,880 - 113,875,792 (-)NCBI
RGSC_v3.47110,232,743 - 110,267,546 (-)RGD
Celera7100,852,648 - 100,887,465 (-)RGD
Sequence:
RefSeq Acc Id: XM_017595136   ⟹   XP_017450625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87106,316,783 - 106,362,452 (-)NCBI
mRatBN7.27104,429,186 - 104,473,924 (-)NCBI
Rnor_6.07113,894,918 - 113,938,397 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_445857 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450625 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF60229 (Get FASTA)   NCBI Sequence Viewer  
  AAG33128 (Get FASTA)   NCBI Sequence Viewer  
  AAK69764 (Get FASTA)   NCBI Sequence Viewer  
  EDM16125 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012408
  ENSRNOP00000012408.1
GenBank Protein Q9ES08 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445857   ⟸   NM_053405
- Peptide Label: precursor
- UniProtKB: Q923V6 (UniProtKB/Swiss-Prot),   Q9JLD4 (UniProtKB/Swiss-Prot),   Q9ES08 (UniProtKB/Swiss-Prot),   A6HRU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450625   ⟸   XM_017595136
- Peptide Label: isoform X1
- UniProtKB: Q923V6 (UniProtKB/Swiss-Prot),   Q9JLD4 (UniProtKB/Swiss-Prot),   Q9ES08 (UniProtKB/Swiss-Prot),   A6HRU7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012408   ⟸   ENSRNOT00000012408
Protein Domains
Potassium channel

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ES08-F1-model_v2 AlphaFold Q9ES08 1-396 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621451 AgrOrtholog
BioCyc Gene G2FUF-33069 BioCyc
Ensembl Genes ENSRNOG00000009265 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012408 ENTREZGENE
  ENSRNOT00000012408.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot
InterPro 2pore_dom_K_chnl UniProtKB/Swiss-Prot
  2pore_dom_K_chnl_TASK UniProtKB/Swiss-Prot
  K_chnl_dom UniProtKB/Swiss-Prot
  KCNK9 UniProtKB/Swiss-Prot
KEGG Report rno:84429 UniProtKB/Swiss-Prot
NCBI Gene 84429 ENTREZGENE
PANTHER POTASSIUM CHANNEL SUBFAMILY K MEMBER 9 UniProtKB/Swiss-Prot
  PTHR11003 UniProtKB/Swiss-Prot
Pfam Ion_trans_2 UniProtKB/Swiss-Prot
PhenoGen Kcnk9 PhenoGen
PRINTS 2POREKCHANEL UniProtKB/Swiss-Prot
  TASK3CHANNEL UniProtKB/Swiss-Prot
  TASKCHANNEL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009265 RatGTEx
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/Swiss-Prot
UniProt A6HRU7 ENTREZGENE, UniProtKB/TrEMBL
  KCNK9_RAT UniProtKB/Swiss-Prot
  Q923V6 ENTREZGENE
  Q9ES08 ENTREZGENE
  Q9JLD4 ENTREZGENE
UniProt Secondary Q923V6 UniProtKB/Swiss-Prot
  Q9JLD4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Kcnk9  potassium two pore domain channel subfamily K member 9  Kcnk9  potassium channel, two pore domain subfamily K, member 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-26 Kcnk9  potassium channel, two pore domain subfamily K, member 9  Kcnk9  potassium channel, subfamily K, member 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Kcnk9  potassium channel, subfamily K, member 9    potassium channel, subfamily K, member 9 (Task-3)  Name updated 1299863 APPROVED
2002-08-07 Kcnk9  potassium channel, subfamily K, member 9 (Task-3)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in cerebellar granule neurons 633172
gene_protein function 78 % inhibited by changing the extracellular pH from 7.3 to 6.3 633172