Mug1 (murinoglobulin 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Mug1 (murinoglobulin 1) Rattus norvegicus
Analyze
Symbol: Mug1
Name: murinoglobulin 1
RGD ID: 621366
Description: Predicted to enable endopeptidase inhibitor activity and protease binding activity. Predicted to be involved in acute-phase response and negative regulation of peptidase activity. Predicted to act upstream of or within embryo implantation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human PZP (PZP alpha-2-macroglobulin like); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: A1i3; alpha x protein; alpha(1)-inhibitor 3 variant I; alpha(1)-inhibitor 3, variant I; alpha-1 inhibitor 3 variant I; alpha-1-inhibitor III; alpha-X protein; LOC100911784; Murinoglobulin 1 homolog; Murinoglobulin 1 homolog (mouse); murinoglobulin-1; murinoglobulin-1-like; plasma proteinase inhibitor alpha-1-inhibitor III
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84156,748,351 - 156,802,132 (+)NCBIGRCr8
mRatBN7.24155,076,270 - 155,130,051 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4155,076,312 - 155,130,051 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4161,340,322 - 161,393,985 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04157,123,785 - 157,177,448 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04155,766,407 - 155,820,067 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04154,676,382 - 154,729,288 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4154,391,647 - 154,729,310 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04221,759,519 - 221,812,407 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44158,283,901 - 158,337,639 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14158,528,836 - 158,582,575 (+)NCBI
Celera4143,909,294 - 143,962,861 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
bexarotene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
buspirone  (EXP)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chloroform  (EXP)
clofibrate  (EXP,ISO)
Cuprizon  (EXP)
cyproconazole  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP)
dibenzofurans  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
doxorubicin  (EXP)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
finasteride  (EXP)
flutamide  (EXP)
furan  (EXP)
gefitinib  (ISO)
genistein  (ISO)
inulin  (ISO)
lead diacetate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosomorpholine  (EXP)
naloxone  (EXP)
naphthalene  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
ozone  (EXP)
paracetamol  (EXP)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
permethrin  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
quercetin  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulindac  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
theophylline  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
Triptolide  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Sequence and acute phase regulation of rat alpha 1-inhibitor III messenger RNA. Braciak TA, etal., J Biol Chem 1988 Mar 15;263(8):3999-4012.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Differential regulation of the two mRNA species of the rodent negative acute phase protein alpha 1-inhibitor 3. Regler R, etal., FEBS Lett 1991 May 6;282(2):368-72.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Identification and sequencing of cDNA clones for the rodent negative acute-phase protein alpha 1-inhibitor 3. Schweizer M, etal., Eur J Biochem 1987 Apr 15;164(2):375-81.
Additional References at PubMed
PMID:2511184   PMID:14580373   PMID:21362503   PMID:22206666   PMID:22516433   PMID:23533145   PMID:32325114  


Genomics

Comparative Map Data
Mug1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84156,748,351 - 156,802,132 (+)NCBIGRCr8
mRatBN7.24155,076,270 - 155,130,051 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4155,076,312 - 155,130,051 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4161,340,322 - 161,393,985 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04157,123,785 - 157,177,448 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04155,766,407 - 155,820,067 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04154,676,382 - 154,729,288 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4154,391,647 - 154,729,310 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04221,759,519 - 221,812,407 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44158,283,901 - 158,337,639 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14158,528,836 - 158,582,575 (+)NCBI
Celera4143,909,294 - 143,962,861 (+)NCBICelera
Cytogenetic Map4q42NCBI
Mug1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396121,815,455 - 121,866,016 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6121,815,500 - 121,866,016 (+)EnsemblGRCm39 Ensembl
GRCm386121,838,496 - 121,889,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6121,838,541 - 121,889,057 (+)EnsemblGRCm38mm10GRCm38
MGSCv376121,788,559 - 121,839,075 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366121,804,160 - 121,854,676 (+)NCBIMGSCv36mm8
Celera6123,675,203 - 123,725,690 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.52NCBI

Variants

.
Variants in Mug1
485 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:20
Count of miRNA genes:20
Interacting mature miRNAs:20
Transcripts:ENSRNOT00000019969
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat

Markers in Region
D4Rat65  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24155,022,860 - 155,022,988 (+)MAPPERmRatBN7.2
Rnor_6.04154,548,343 - 154,548,470NCBIRnor6.0
Rnor_5.04221,631,462 - 221,631,589UniSTSRnor5.0
RGSC_v3.44158,230,217 - 158,230,345RGDRGSC3.4
RGSC_v3.44158,230,218 - 158,230,345UniSTSRGSC3.4
RGSC_v3.14158,475,154 - 158,475,281RGD
Celera4143,855,885 - 143,856,024UniSTS
RH 3.4 Map4995.11UniSTS
RH 3.4 Map4995.11RGD
SHRSP x BN Map478.1999UniSTS
SHRSP x BN Map478.1999RGD
Cytogenetic Map4q42UniSTS
D4Won45  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24155,097,857 - 155,098,120 (+)MAPPERmRatBN7.2
Rnor_6.04154,697,097 - 154,697,357NCBIRnor6.0
Rnor_6.04154,618,941 - 154,619,199NCBIRnor6.0
Rnor_5.04221,702,060 - 221,702,318UniSTSRnor5.0
Rnor_5.04221,780,216 - 221,780,476UniSTSRnor5.0
RGSC_v3.44158,305,447 - 158,305,707UniSTSRGSC3.4
Celera4143,930,710 - 143,930,930UniSTS
Cytogenetic Map4q42UniSTS
RH143613  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map4997.7UniSTS
Cytogenetic Map4q42UniSTS
AU047685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24154,993,866 - 154,994,029 (+)MAPPERmRatBN7.2
Rnor_6.04154,519,665 - 154,519,827NCBIRnor6.0
Rnor_5.04221,602,784 - 221,602,946UniSTSRnor5.0
RGSC_v3.44158,201,202 - 158,201,364UniSTSRGSC3.4
Celera4143,826,931 - 143,827,093UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 9 14 51 85 81 53 23 53 6 145 58 31 20 38 28

Sequence


Ensembl Acc Id: ENSRNOT00000019969   ⟹   ENSRNOP00000019969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4155,076,312 - 155,130,051 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079192   ⟹   ENSRNOP00000069175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4155,076,312 - 155,129,655 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108828   ⟹   ENSRNOP00000082949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4155,076,312 - 155,129,655 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119571   ⟹   ENSRNOP00000093643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4155,076,312 - 155,129,655 (+)Ensembl
RefSeq Acc Id: NM_023103   ⟹   NP_075591
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84156,748,395 - 156,802,132 (+)NCBI
mRatBN7.24155,076,312 - 155,130,051 (+)NCBI
Rnor_6.04154,676,427 - 154,729,288 (+)NCBI
Rnor_5.04221,759,519 - 221,812,407 (+)NCBI
RGSC_v3.44158,283,901 - 158,337,639 (+)RGD
Celera4143,909,294 - 143,962,861 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237282   ⟹   XP_006237344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84156,748,351 - 156,801,751 (+)NCBI
mRatBN7.24155,076,270 - 155,129,670 (+)NCBI
Rnor_6.04154,676,382 - 154,728,907 (+)NCBI
Rnor_5.04221,759,519 - 221,812,407 (+)NCBI
Sequence:
RefSeq Acc Id: NP_075591   ⟸   NM_023103
- Peptide Label: precursor
- UniProtKB: Q9JMK7 (UniProtKB/Swiss-Prot),   Q78DZ4 (UniProtKB/Swiss-Prot),   Q63023 (UniProtKB/Swiss-Prot),   Q63020 (UniProtKB/Swiss-Prot),   Q63018 (UniProtKB/Swiss-Prot),   Q03626 (UniProtKB/Swiss-Prot),   Q03310 (UniProtKB/Swiss-Prot),   D4A6E3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237344   ⟸   XM_006237282
- Peptide Label: isoform X1
- UniProtKB: D4A6E3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069175   ⟸   ENSRNOT00000079192
Ensembl Acc Id: ENSRNOP00000093643   ⟸   ENSRNOT00000119571
Ensembl Acc Id: ENSRNOP00000019969   ⟸   ENSRNOT00000019969
Ensembl Acc Id: ENSRNOP00000082949   ⟸   ENSRNOT00000108828
Protein Domains
Alpha-2-macroglobulin   Alpha-2-macroglobulin bait region   Alpha-macroglobulin receptor-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q03626-F1-model_v2 AlphaFold Q03626 1-1487 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693369
Promoter ID:EPDNEW_R3892
Type:multiple initiation site
Name:LOC297568_1
Description:alpha-1-inhibitor III
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3891  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04154,676,399 - 154,676,459EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621366 AgrOrtholog
BioCyc Gene G2FUF-43169 BioCyc
Ensembl Genes ENSRNOG00000037188 Ensembl
  ENSRNOG00000067685 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055011345 UniProtKB/Swiss-Prot
  ENSRNOG00060031936 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019969.7 UniProtKB/TrEMBL
  ENSRNOT00000079192.2 UniProtKB/TrEMBL
  ENSRNOT00000108828.1 UniProtKB/TrEMBL
  ENSRNOT00000119571.1 UniProtKB/TrEMBL
  ENSRNOT00055019262 UniProtKB/Swiss-Prot
  ENSRNOT00060055392 UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.10.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.20.130.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.1540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1930 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1940 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.690 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.20.50.160 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A-macroglobulin_rcpt-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A-macroglobulin_rcpt-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M/Complement_sys UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M_N_BRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M_TED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha-macroglob_thiol-ester_cl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha-macroglobulin_TED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Macroglobln_a2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MacrogloblnA2_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MG3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MG4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Terpenoid_cyclase/PrenylTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TonB_box_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:497794 UniProtKB/Swiss-Prot
NCBI Gene Mug1 ENTREZGENE
PANTHER MACROGLOBULIN / COMPLEMENT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MURINOGLOBULIN-1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam A2M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M_BRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MG3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MG4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TED_complement UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mug1 PhenoGen
PROSITE ALPHA_2_MACROGLOBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TONB_DEPENDENT_REC_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000037188 RatGTEx
  ENSRNOG00000067685 RatGTEx
  ENSRNOG00055011345 RatGTEx
  ENSRNOG00060031936 RatGTEx
SMART A2M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A2M_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thiol-ester_cl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49410 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUP5_RAT UniProtKB/TrEMBL
  A0A8I5ZV18_RAT UniProtKB/TrEMBL
  A0A8I6AJZ9_RAT UniProtKB/TrEMBL
  D4A6E3 ENTREZGENE, UniProtKB/TrEMBL
  MUG1_RAT UniProtKB/Swiss-Prot
  Q03310 ENTREZGENE
  Q03626 ENTREZGENE
  Q63018 ENTREZGENE
  Q63020 ENTREZGENE
  Q63023 ENTREZGENE
  Q78DZ4 ENTREZGENE
  Q9JMK7 ENTREZGENE
UniProt Secondary Q03310 UniProtKB/Swiss-Prot
  Q63018 UniProtKB/Swiss-Prot
  Q63020 UniProtKB/Swiss-Prot
  Q63023 UniProtKB/Swiss-Prot
  Q78DZ4 UniProtKB/Swiss-Prot
  Q9JMK7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mug1  murinoglobulin 1  LOC100911784  murinoglobulin-1-like  Data merged from RGD:6491022 737654 PROVISIONAL
2012-07-05 LOC100911784  murinoglobulin-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-22 Mug1  murinoglobulin 1  Mug1  Murinoglobulin 1 homolog (mouse)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Mug1  Murinoglobulin 1 homolog (mouse)    alpha(1)-inhibitor 3, variant I  Name updated 1299863 APPROVED
2002-08-07 Mug1  alpha(1)-inhibitor 3, variant I      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology shows 58% overall sequence identity with rat alpha 2-macroglobulin  
gene_protein 1477-amino acid precursor polypeptide