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Gene: Kcnc3 (potassium voltage-gated channel subfamily C member 3) Rattus norvegicus

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Symbol:

Kcnc3

Name:

potassium voltage-gated channel subfamily C member 3

RGD ID:

621358

Description:

Enables voltage-gated potassium channel activity. Involved in corpus callosum development and optic nerve development. Located in dendrite. Is active in glutamatergic synapse; postsynaptic membrane; and presynaptic membrane. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 13. Orthologous to human KCNC3 (potassium voltage-gated channel subfamily C member 3); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

KShIIID; Kv3.3; potassium channel, voltage gated Shaw-related subfamily C, member 3; potassium voltage gated channel, Shaw-related subfamily, member 3; voltage-gated potassium channel KCNC3; voltage-gated potassium channel subunit Kv3.3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,217,472 - 104,231,677 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	104,217,472 - 104,231,672 (+)	Ensembl				GRCr8
mRatBN7.2	1	95,080,960 - 95,095,165 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,080,960 - 95,095,160 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	100,466,349 - 100,480,553 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	108,939,005 - 108,953,209 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,229,418 - 102,243,622 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,593,453 - 100,607,874 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,593,680 - 100,607,874 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	101,658,860 - 101,673,261 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	95,066,641 - 95,080,847 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	89,343,211 - 89,357,385 (+)	NCBI		Celera
RGSC_v3.1	1	95,144,751 - 95,158,955 (+)	NCBI
RH 3.4 Map	1	905.4	RGD
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

spinocerebellar ataxia 13 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

buta-1,3-diene (ISO)

butanal (ISO)

carbon nanotube (ISO)

copper atom (EXP)

copper(0) (EXP)

dicrotophos (ISO)

dorsomorphin (ISO)

ethanol (EXP)

fenvalerate (EXP)

finasteride (EXP)

gentamycin (EXP)

hydrogen peroxide (ISO)

inulin (ISO)

maneb (ISO)

methimazole (EXP)

methotrexate (ISO)

nifedipine (EXP)

nitrofen (EXP)

okadaic acid (ISO)

omega-conotoxin GVIA (EXP)

paracetamol (EXP,ISO)

paraquat (EXP,ISO)

PCB138 (ISO)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

potassium chloride (EXP)

raspberry ketone (ISO)

SB 431542 (ISO)

sulfadimethoxine (EXP)

T-2 toxin (ISO)

tetrachloromethane (EXP)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

action potential (IBA)

corpus callosum development (IEP)

cortical actin cytoskeleton organization (ISO,ISS)

forebrain development (IEA)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

optic nerve development (IEA,IEP)

potassium ion transmembrane transport (IBA,IEA,ISO,ISS)

potassium ion transport (IEA,ISO,ISS)

protein homooligomerization (IEA)

protein tetramerization (ISO,ISS)

regulation of neurotransmitter secretion (ISO)

regulation of synaptic vesicle endocytosis (ISO)

transmembrane transport (IEA)

Cellular Component

axolemma (ISO)

axon (IEA)

axon terminus (IBA,ISO)

calyx of Held (ISO)

cell cortex (IEA,ISO)

cytoskeleton (IEA)

dendrite (IDA,IEA,ISO)

dendrite membrane (IBA,ISO)

dendritic spine membrane (IEA)

glutamatergic synapse (IDA)

membrane (IEA)

monoatomic ion channel complex (IEA)

neuromuscular junction (ISO)

neuron projection (IEA)

neuronal cell body membrane (IBA,ISO)

perikaryon (IEA)

plasma membrane (IEA,ISO,ISS)

postsynaptic membrane (IBA,IDA)

presynaptic membrane (IBA,IDA,IEA)

voltage-gated potassium channel complex (IBA,IEA,ISO,ISS)

Molecular Function

delayed rectifier potassium channel activity (IBA)

metal ion binding (IEA)

monoatomic ion channel activity (IEA)

potassium channel activity (IEA)

protein binding (ISO)

voltage-gated potassium channel activity (IDA,IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Frequency of KCNC3 DNA variants as causes of spinocerebellar ataxia 13 (SCA13).	Figueroa KP, etal., PLoS One. 2011 Mar 29;6(3):e17811. doi: 10.1371/journal.pone.0017811.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain.	Huang CY, etal., J Comp Neurol. 2012 Nov 1;520(16):3650-72. doi: 10.1002/cne.23119.
5.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	Precise localization of the voltage-gated potassium channel subunits Kv3.1b and Kv3.3 revealed in the molecular layer of the rat cerebellar cortex by a pre-embedding immunogold method.	Puente N, etal., Histochem Cell Biol. 2010 Oct;134(4):403-9. doi: 10.1007/s00418-010-0742-6. Epub 2010 Sep 21.
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Cloning of ShIII (Shaw-like) cDNAs encoding a novel high-voltage-activating, TEA-sensitive, type-A K+ channel.	Vega-Saenz de Miera E, etal., Proc R Soc Lond B Biol Sci 1992 Apr 22;248(1321):9-18.

Additional References at PubMed

PMID:15240761	PMID:15610163	PMID:16403474	PMID:18682278	PMID:19953606	PMID:23734863	PMID:25152487	PMID:25756792

Genomics

Comparative Map Data

Kcnc3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,217,472 - 104,231,677 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	104,217,472 - 104,231,672 (+)	Ensembl				GRCr8
mRatBN7.2	1	95,080,960 - 95,095,165 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,080,960 - 95,095,160 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	100,466,349 - 100,480,553 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	108,939,005 - 108,953,209 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,229,418 - 102,243,622 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,593,453 - 100,607,874 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,593,680 - 100,607,874 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	101,658,860 - 101,673,261 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	95,066,641 - 95,080,847 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	89,343,211 - 89,357,385 (+)	NCBI		Celera
RGSC_v3.1	1	95,144,751 - 95,158,955 (+)	NCBI
RH 3.4 Map	1	905.4	RGD
Cytogenetic Map	1	q22	NCBI

KCNC3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,311,937 - 50,333,536 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,311,937 - 50,333,515 (-)	Ensembl			hg38	GRCh38
GRCh37	19	50,815,194 - 50,836,793 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,510,577 - 55,524,446 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	55,510,576 - 55,524,446	NCBI
Celera	19	47,869,096 - 47,882,964 (-)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	47,156,998 - 47,170,888 (-)	NCBI		HuRef
CHM1_1	19	50,820,581 - 50,834,417 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	53,399,467 - 53,421,072 (-)	NCBI		T2T-CHM13v2.0

Kcnc3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,236,405 - 44,254,175 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,240,088 - 44,254,178 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	44,586,939 - 44,604,751 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,590,664 - 44,604,754 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	51,846,256 - 51,860,121 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,459,162 - 44,464,606 (+)	NCBI		MGSCv36	mm8
Celera	7	40,040,752 - 40,054,619 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.85	NCBI

Kcnc3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955559	782,842 - 795,455 (+)	NCBI	ChiLan1.0	ChiLan1.0

KCNC3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	56,380,228 - 56,394,491 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	58,298,616 - 58,315,820 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	47,275,213 - 47,296,809 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	56,180,048 - 56,200,789 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

KCNC3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,366,657 - 106,371,062 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	105,938,945 - 105,953,893 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	106,876,948 - 106,891,910 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	106,876,948 - 106,889,808 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,549,006 - 106,563,944 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,190,556 - 106,205,438 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,031,217 - 107,046,175 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Kcnc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,310,012 - 22,327,824 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936889	192,129 - 202,519 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936889	185,349 - 203,847 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KCNC3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,204,101 - 55,217,074 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	55,204,045 - 55,216,875 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,050,617 - 51,065,728 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KCNC3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,374,151 - 43,391,418 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	23,357,494 - 23,375,607 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kcnc3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,161,068 - 4,175,721 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624832	4,161,510 - 4,175,744 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Kcnc3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	154,930,242 - 154,944,622 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Kcnc3
91 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	459
Count of miRNA genes:	208
Interacting mature miRNAs:	279
Transcripts:	ENSRNOT00000027062, ENSRNOT00000027063
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	92963855	109494029	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	92683681	137683681	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	97582336	142582336	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	100345976	145345976	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat

Markers in Region

BF392914

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,086,631 - 95,086,734 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,599,341 - 100,599,443	NCBI	Rnor6.0
Rnor_5.0	1	101,664,728 - 101,664,830	UniSTS	Rnor5.0
RGSC_v3.4	1	95,072,313 - 95,072,415	UniSTS	RGSC3.4
Celera	1	89,348,883 - 89,348,985	UniSTS
RH 3.4 Map	1	904.29	UniSTS
Cytogenetic Map	1	q22	UniSTS

BE097167

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,090,013 - 95,090,226 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,602,723 - 100,602,935	NCBI	Rnor6.0
Rnor_5.0	1	101,668,110 - 101,668,322	UniSTS	Rnor5.0
RGSC_v3.4	1	95,075,695 - 95,075,907	UniSTS	RGSC3.4
Celera	1	89,352,265 - 89,352,477	UniSTS
RH 3.4 Map	1	903.4	UniSTS
Cytogenetic Map	1	q22	UniSTS

RH94540

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,086,653 - 95,086,743 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,599,363 - 100,599,452	NCBI	Rnor6.0
Rnor_5.0	1	101,664,750 - 101,664,839	UniSTS	Rnor5.0
RGSC_v3.4	1	95,072,335 - 95,072,424	UniSTS	RGSC3.4
Celera	1	89,348,905 - 89,348,994	UniSTS
RH 3.4 Map	1	905.4	UniSTS
Cytogenetic Map	1	q22	UniSTS

BG373666

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,094,934 - 95,095,153 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,607,644 - 100,607,862	NCBI	Rnor6.0
Rnor_5.0	1	101,673,031 - 101,673,249	UniSTS	Rnor5.0
RGSC_v3.4	1	95,080,617 - 95,080,835	UniSTS	RGSC3.4
Celera	1	89,357,155 - 89,357,373	UniSTS
RH 3.4 Map	1	903.3	UniSTS
Cytogenetic Map	1	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	3	64	156	68	67	41	56	41	6	288	147	7	137	81	91	26	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588695	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588696	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY179603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY179604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY822673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY822674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M84210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M84211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027062 ⟹ ENSRNOP00000027062

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	104,217,483 - 104,227,990 (+)	Ensembl
mRatBN7.2 Ensembl	1	95,080,971 - 95,091,478 (+)	Ensembl
Rnor_6.0 Ensembl	1	100,593,892 - 100,604,068 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000027063 ⟹ ENSRNOP00000027063

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	104,217,472 - 104,231,672 (+)	Ensembl
mRatBN7.2 Ensembl	1	95,080,960 - 95,095,160 (+)	Ensembl
Rnor_6.0 Ensembl	1	100,593,680 - 100,607,874 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078153 ⟹ ENSRNOP00000072439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	104,217,483 - 104,229,070 (+)	Ensembl
mRatBN7.2 Ensembl	1	95,080,971 - 95,092,558 (+)	Ensembl
Rnor_6.0 Ensembl	1	100,593,680 - 100,605,267 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000125629 ⟹ ENSRNOP00000104568

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	104,217,483 - 104,226,534 (+)	Ensembl

RefSeq Acc Id:

NM_053997 ⟹ NP_446449

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,217,472 - 104,231,677 (+)	NCBI
mRatBN7.2	1	95,080,960 - 95,095,165 (+)	NCBI
Rnor_6.0	1	100,593,669 - 100,607,874 (+)	NCBI
Rnor_5.0	1	101,658,860 - 101,673,261 (+)	NCBI
RGSC_v3.4	1	95,066,641 - 95,080,847 (+)	RGD
Celera	1	89,343,211 - 89,357,385 (+)	RGD

Sequence:

show sequence

AAGCTTTTTGTGCAATCCCACCTCCTCTAGCTAGGCTTGGTTAGAGTCTGCCTAGCCGTGGCCC
CGCCCACTCCATCAGTCCAATCAGCTCGTGTTCTCCCTCCACCTGCCCAATCACTCCCTCCCCA
TCCATTCATCGCCTCCTCCTGCCCAATCACATCTGCTTCTCTACCAAGGCTCCGCCCCAACACC
CTGCCCCCCTCAGCCCCGCCTCCCTGTCCAATGCTCAGCTCAGTGTGCGTCTGGTCGTTCAGCG
GGCGCCAGGGGACCCGCAAGCAGCATTCTCAGCCGGCGCCAACGCCGCAGCCGCCTGAGTCCTC
ACCGCCGCCTCTGCTACCGCCGCCGCAGCAGCAGTGCGCTCAGCCCGGCACCGCCGCCTCCCCG
GCGGGTGCCCCGCTTTCCTGTGGGCCTGGGGGCCGGCGCGCCGAGCCATGCTCCGGGCTGCCGG
CGGTGGCCATGGGGCGGCACGGCGGCGGCGGCGGCGACAGCGGTAAGATCGTGATCAACGTGGG
CGGCGTGCGCCATGAGACGTACCGCTCCACGTTGCGCACCCTACCGGGGACCCGGCTGGCCGGG
CTGACCGAGCCCGAGGCGGCCGCGCGCTTTGACTACGACCCGGGCACGGACGAGTTCTTCTTTG
ACCGTCACCCGGGCGTCTTCGCCTACGTGCTCAACTACTACCGCACCGGCAAGCTGCACTGCCC
GGCCGACGTGTGCGGGCCGCTCTTCGAGGAGGAGCTGGGCTTCTGGGGCATAGACGAGACGGAC
GTGGAGGCCTGCTGCTGGATGACCTACCGCCAGCACCGTGATGCCGAAGAGGCACTGGACTCCT
TCGAGGCTCCGGACTCCTCGGGCAACGCCAACGCCAACGCCGGAGGCGCCCATGATGCGGGCCT
GGACGACGAGGCGGGCGCAGGAGGTGGCGGCCTGGACGGGGCAGGCGGCGAGCTCAAGCGTCTG
TGTTTTCAGGACGCGGGCGGAGGTGCCGGAGGACCTGCCGGAGGCCCGGGCGGCGCGGGCGGCA
CGTGGTGGAGGCGCTGGCAGCCCCGCGTGTGGGCGCTTTTTGAGGACCCCTACTCGTCGCGGGC
CGCCAGGTACGTGGCCTTCGCCTCCCTATTCTTTATCCTCATCTCCATCACCACCTTCTGCCTG
GAGACACACGAGGGCTTCATCCACATCAGCAACAAGACGGTGACGCAGGCCTCTCCAATCCCTG
GGGCTCCCCCGGAGAATATCACCAATGTGGAGGTGGAGACGGAACCCTTTTTGACCTACGTGGA
AGGCGTGTGTGTGGTCTGGTTCACCTTTGAGTTTCTCATGCGGGTCACCTTCTGCCCGGATAAG
GTGGAGTTTCTCAAAAGCAGTCTTAACATCATCGACTGTGTAGCCATCTTGCCCTTCTACTTGG
AAGTGGGCCTGTCAGGTCTCAGCTCCAAAGCTGCCAAGGACGTGCTGGGCTTCCTGCGCGTCGT
CCGCTTCGTGCGCATCCTCCGTATCTTCAAGCTGACCCGCCATTTTGTGGGCCTGCGGGTCCTG
GGCCACACGCTCCGTGCCAGCACCAACGAGTTCTTGTTACTCATTATTTTCCTGGCTCTGGGGG
TCCTCATCTTTGCCACCATGATCTACTATGCCGAGCGCATCGGGGCCGATCCTGATGACATCCT
GGGCTCCAACCACACCTACTTCAAGAACATCCCCATCGGCTTCTGGTGGGCTGTGGTCACCATG
ACCACACTGGGCTATGGTGACATGTACCCCAAGACATGGTCTGGGATGCTGGTCGGGGCACTGT
GTGCCCTGGCTGGTGTGCTGACCATTGCCATGCCGGTGCCCGTCATTGTCAACAACTTCGGCAT
GTACTATTCACTGGCTATGGCCAAGCAGAAATTGCCAAAGAAGAAAAACAAACATATCCCCAGG
CCCCCGCAGCCTGGCTCACCCAACTACTGCAAGCCCGATCCCCCGCCTCCGCCCCCACCACACC
CCCACCACGGCAGCGGTGGCATCAGCCCACCACCGCCCATCACCCCTCCTTCCATGGGGGTGAC
TGTGGCTGGGGCTTACCCACCTGGACCCCACACGCACCCCGGGCTGCTTAGGGGTGGTGCTGGG
GGACTGGGAATTATGGGATTGCCTCCTCTGCCAGCCCCTGGTGAGCCCTGCCCACTGGCTCAAG
AAGAGGTGATTGAAACCAACAGGGCAGACCCCCGTCCCAATGGAGACCCTGCAGCAGCTGCACT
GGCTCATGAGGACTGCCCCGCCATTGACCAGCCAGCCATGTCTCCAGAAGACAAGAGCCCGATC
ACTCCCGGAAGCCGGGGTCGCTACAGCCGGGACCGAGCTTGCTTCCTTGTCACAGACTATGCCC
CTTCCCCCGATGGCTCCATCCGAAAAGGTTACGAGAAGTCCCGCAGCCTGAGCAGCATTGTGGG
CCTGAGCGGGGTGTCCCTGCGCCTCGCGCCCCTCGCCACCCCCCCTGGCTCTCCCCGGGCCACG
CGCCGAGCTCCCCCGACCCTGCCCTCCATCCTCTAGCGCTGTCCTCCCCCCTGTGGGGGGACTG
GGGGTGATGGGAAGGTGAAAAGGAGCTGGGAGAAGGGGTGGGGAAAGGGTTATTTAAAAAAAAA
AGTTAATAATATGCAAAAGATGATGCCAGCAGACACCCCCGGGGCCTCTCACTCCCCATATAGT
AGAGAACCAAATAGAAGGGGGGCGGGGCCGGAGCCTGTACCCCCACAACTCCCTCCCCTTTCCC
CCCCCAAAAAATGCAAACCTCAGGTCTCCATGAGCCATAGGACACCCCTCCCATCGACTCCTGT
AAATAACTAAAAGCCGATTCCATCTTGGGGCACCCACTCCAGTTTGCATGCCTCTCCGACCCCC
CTCTTCAGCAATAAGCCGCCAGGAGCTGCGTGCAGAGAGTTGGAGGGGAGGCTGCTGGGAGCCT
CTGGGGTCGGGGCTAGCATTTTAGGGGTCTTCCTGGATACCCCGCCAAAAGGCAACCCACCCAC
CACTAATTGATTCAGGAAAAACAAAAACCTCTAGGAACACGTAGGAAAAGGAAGACAGGTTAAT
CAGCTGCAACCCCGAGGAGCTCAGCGTGGGGGTGGGGGTGGGGTTCTGCCAGCTGCTCTTGGGC
TTGGAGGACGCCAGCTGGTGCATTCCACCCACGCCCGCCTCCAGAGATCTGCTCCCTCTATTCG
CTGCATGGACTTGGCCCTCCAGGCCCAGAACCCTCTCTACCCATTGCAGTCTCCACTCTATCCC
AATGTGAGACTAGTACCCTAGACTTACGGAGATAGAACCTGGCACCCTGCACTCCCATACCCCA
CGGACTCCGGCGCCCCACACTTCCCACCTCCATCACTCCATCCCCCACTGGCCTGGACTGCACC
ACAGAGTTCTTCCACCCTTTCCTTGCACCCCAGCTCACTTCCAGCCATTGGGGTTCTGACAGTC
CTCAAGACCCTGACATATCTAGACACCCCCATATCCTCAAGCCTCCCCCAACCCCAGACAGCCC
CAACCCTCTGATATCACATTTCTCTGTCCTGGGCGCCTCTGACGCAAGACCTTCCGGGACAAGC
TCTGATTCCAGGGAGCTCCCACCCCATTCCAGCATCGCTGTCTAGGCAGCCCCCTCCTCTACGC
TTCCCCCCCCCCCATGGTGCCAAAACACATTTTCTTCATGGCCACCAGAGTTTCCCAGAGCGTG
GGACTCCCGTTCCCTCTTCGCATGCTGAACTTTGCAGAGTGCACAGACGACCAAGTGTTTTAAA
ATTGTGTACTCTTCGCAAGCTCATACCCGGCTGGTGCGTCCTGGCAGCGTAGCAGTTGGGCGTT
GCCATTGAAAGCAAGTCAAGGACAGGATGGGACCCAATGCTAAAAGCGCTGGCTTAATGTGCTA
AGGTCCCAGGGTTCAATCTCCAGCAATCCCTCTTTGCCCGACCGGTGGGAAAAGAGGACACGCC
CACCTCGGCTAGGATCTTAGCCTGCCCTTCCCAGCTTCCTTGCCCACCGCGTGCCACATTCGCG
GGTGGAAAACTTTCTCAAATCTCGTCTTGGCTCCAGGATGCTACCTCCCCTAAGCCCAGAGACC
ACACTGGTCCCAGAATCCTTAGTGAACTTCCCCTTTTGGAGCTGGGTGGTCGGCAGAATTAGCA
ATCCCTTGTTCCCACCGCCTCAGGGAAACCTCCCGCTGTCACCAGAGTTGTCGGTGGGGGTGTC
CTTGGGCCCAATTCTTGATGCAACAATTCCTATGCAAGGGACATTTTGAGTCCCTCCCGCACTC
CCCGCCTTCCCTCGGGACCTTAAACCCTGGTGAGACAGGGGTTGAGGAGTGGGGTGGGATCTGG
TAGGGGCAGGGCAAAGGGCTAGGGGACTCTAGACACCAGGGTATGGGGTGAGGACTCCTAATAT
TGCCAAAGGATTCAACTTATTTAAACAACCCCTATTACCCCCCCCCCCGTCCCTCAAAAGAGCG
AATGGGGCGGGGAAAGGGGTAAGAGTCCTTTTTGAAGGGTACCAACCACTTCCCACTGTTTCAC
CCTGTGCTCTCCAGTCCCCTACACATATCCAGCTTTTTAGTTAAGCATTTTTAAAAAGCTACAG
TTCATTATAAACGTCTACAAAACGTGATTTTTGCCCCTCCACATTTCCCAATTTACCAAACAGT
GTGGGATTCGGGGAGGGAGAGCCAGTCCTGGTCTCCCTTTTCCCCACGGCCGCCAGGGTGCCTG
CAACTGCACGCATGCGCTGCATGACGCGCCCCCCCACATACACACGCATGCGTCGCGCACCCCT
CCTGCGCTGGGGGGGGACGCACGGACTTGGGGGCGGGGCGATGGGGAGGAATGATTGGCAGAGG
GGAAGGGGGTTTTTCTGAGCTCAATGGCTCCTCTCCTTCCCCACACACTCAACAGCAATAAGTT
TCTCTACTTCAAGTGGGCGGACGGGCCTAGCCTGACCTGGCGCGGGAGGGGCTGGCCAAGGGGC
GCTCTCAGGGATGGGGGCGGGTCCTGAGTCTGGGGGAGGGGAGGTCTGCAACTCTGGTGCTAAT
GGCGGGTCTTCCTGGCCCACCCGCAGGCAGGGAGGAAGGAGTCGGCAGGCTCCTCCCCCAAGCC
TCCCCCACGCCCACCCAGGGTGCATGAACCACCCACGCAGAAGCTGCCGCATGTCAACCCTCCC
CCCAACAAAGAAACAGTGTCATGCCCCTCCCCACCTGCCCTCCCACTCCCCAGCCCAATAAATG
ATTCCTTTTCATTTACAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_446449	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41470	(Get FASTA)	NCBI Sequence Viewer
	AAA73182	(Get FASTA)	NCBI Sequence Viewer
	AAO23560	(Get FASTA)	NCBI Sequence Viewer
	AAO23561	(Get FASTA)	NCBI Sequence Viewer
	AAV80432	(Get FASTA)	NCBI Sequence Viewer
	AAV80433	(Get FASTA)	NCBI Sequence Viewer
	EDM07466	(Get FASTA)	NCBI Sequence Viewer
	EDM07467	(Get FASTA)	NCBI Sequence Viewer
	EDM07468	(Get FASTA)	NCBI Sequence Viewer
	EDM07469	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027063
GenBank Protein	Q01956	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446449 ⟸ NM_053997

- UniProtKB:

Q811T3 (UniProtKB/TrEMBL), F1MAD4 (UniProtKB/TrEMBL), A0A8J8XF86 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSSVCVWSFSGRQGTRKQHSQPAPTPQPPESSPPPLLPPPQQQCAQPGTAASPAGAPLSCGPG
GRRAEPCSGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARF
DYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYR
QHRDAEEALDSFEAPDSSGNANANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAG
GPAGGPGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHIS
NKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNI
IDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNE
FLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYP
KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYC
KPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPPGPHTHPGLLRGGAGGLGIMGLPPL
PAPGEPCPLAQEEVIETNRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSR
DRACFLVTDYAPSPDGSIRKGYEKSRSLSSIVGLSGVSLRLAPLATPPGSPRATRRAPPTLPSI
L

hide sequence

Ensembl Acc Id:

ENSRNOP00000072439 ⟸ ENSRNOT00000078153

Ensembl Acc Id:

ENSRNOP00000027063 ⟸ ENSRNOT00000027063

Ensembl Acc Id:

ENSRNOP00000027062 ⟸ ENSRNOT00000027062

Ensembl Acc Id:

ENSRNOP00000104568 ⟸ ENSRNOT00000125629

Protein Domains

BTB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q01956-F1-model_v2	AlphaFold	Q01956	1-889	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690006

Promoter ID:

EPDNEW_R528

Type:

multiple initiation site

Name:

Kcnc3_1

Description:

potassium voltage-gated channel subfamily C member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	100,593,903 - 100,593,963	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621358	AgrOrtholog
BioCyc Gene	G2FUF-59758	BioCyc
Ensembl Genes	ENSRNOG00000019959	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000027063	ENTREZGENE
Gene3D-CATH	1.10.287.70	UniProtKB/Swiss-Prot
	1.20.120.350	UniProtKB/Swiss-Prot
	Potassium Channel Kv1.1, Chain A	UniProtKB/Swiss-Prot
InterPro	BTB/POZ_dom	UniProtKB/Swiss-Prot
	Ion_trans_dom	UniProtKB/Swiss-Prot
	K_chnl_volt-dep_Kv	UniProtKB/Swiss-Prot
	K_chnl_volt-dep_Kv3	UniProtKB/Swiss-Prot
	K_chnl_volt-dep_Kv3.3	UniProtKB/Swiss-Prot
	SKP1/BTB/POZ_sf	UniProtKB/Swiss-Prot
	T1-type_BTB	UniProtKB/Swiss-Prot
	VG_K_chnl	UniProtKB/Swiss-Prot
	Volt_channel_dom_sf	UniProtKB/Swiss-Prot
NCBI Gene	117101	ENTREZGENE
PANTHER	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 3	UniProtKB/Swiss-Prot
	PTHR11537	UniProtKB/Swiss-Prot
Pfam	BTB_2	UniProtKB/Swiss-Prot
	Ion_trans	UniProtKB/Swiss-Prot
PhenoGen	Kcnc3	PhenoGen
PRINTS	KCHANNEL	UniProtKB/Swiss-Prot
	KV33CHANNEL	UniProtKB/Swiss-Prot
	KVCHANNEL	UniProtKB/Swiss-Prot
	SHAWCHANNEL	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000019959	RatGTEx
SMART	BTB	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54695	UniProtKB/Swiss-Prot
	Voltage-gated potassium channels	UniProtKB/Swiss-Prot
UniProt	A0A8J8XF86	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LG30_RAT	UniProtKB/TrEMBL
	A6JAR6_RAT	UniProtKB/TrEMBL
	A6JAR8_RAT	UniProtKB/TrEMBL
	F1LP15_RAT	UniProtKB/TrEMBL
	F1MAD4	ENTREZGENE
	KCNC3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q5PXK5_RAT	UniProtKB/TrEMBL
	Q5PXK6_RAT	UniProtKB/TrEMBL
	Q811T2_RAT	UniProtKB/TrEMBL
	Q811T3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Kcnc3	potassium voltage-gated channel subfamily C member 3	Kcnc3	potassium channel, voltage gated Shaw-related subfamily C, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-01-26	Kcnc3	potassium channel, voltage gated Shaw-related subfamily C, member 3	Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-02-26	Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	highly sensitive to tetraethylamonium	727556
gene_process	involved in neuronal excitability	727556

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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