Nova1 (NOVA alternative splicing regulator 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Nova1 (NOVA alternative splicing regulator 1) Rattus norvegicus
Analyze
Symbol: Nova1
Name: NOVA alternative splicing regulator 1
RGD ID: 621345
Description: Predicted to enable mRNA 3'-UTR binding activity and sequence-specific mRNA binding activity. Involved in regulation of mRNA processing and spinal cord development. Predicted to be active in cytoplasm and nucleus. Orthologous to human NOVA1 (NOVA alternative splicing regulator 1); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neuro-oncological ventral antigen 1; Nova-1; RNA-binding protein Nova-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8669,506,983 - 69,632,437 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl669,506,983 - 69,632,437 (-)EnsemblGRCr8
mRatBN7.2663,780,105 - 63,905,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl663,783,489 - 63,906,289 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx664,171,614 - 64,293,460 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0664,486,772 - 64,608,608 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0663,933,525 - 64,055,455 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0666,960,126 - 67,085,836 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl666,963,510 - 67,085,390 (-)Ensemblrn6Rnor6.0
Rnor_5.0676,535,375 - 76,660,962 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4666,193,472 - 66,320,240 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera662,747,220 - 62,869,241 (-)NCBICelera
RGSC_v3.1666,202,073 - 66,323,082 (-)NCBI
Cytogenetic Map6q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Role of Nova-1 in regulating alpha2N, a novel glycine receptor splice variant, in developing spinal cord neurons. Kumar DV, etal., J Neurobiol 2002 Aug;52(2):156-65.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. An alternative splicing program promotes adipose tissue thermogenesis. Vernia S, etal., Elife. 2016 Sep 16;5. doi: 10.7554/eLife.17672.
Additional References at PubMed
PMID:10719891   PMID:22681889   PMID:23042482   PMID:23359859   PMID:25249621   PMID:26105073   PMID:27378374   PMID:28791345   PMID:33799408  


Genomics

Comparative Map Data
Nova1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8669,506,983 - 69,632,437 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl669,506,983 - 69,632,437 (-)EnsemblGRCr8
mRatBN7.2663,780,105 - 63,905,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl663,783,489 - 63,906,289 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx664,171,614 - 64,293,460 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0664,486,772 - 64,608,608 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0663,933,525 - 64,055,455 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0666,960,126 - 67,085,836 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl666,963,510 - 67,085,390 (-)Ensemblrn6Rnor6.0
Rnor_5.0676,535,375 - 76,660,962 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4666,193,472 - 66,320,240 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera662,747,220 - 62,869,241 (-)NCBICelera
RGSC_v3.1666,202,073 - 66,323,082 (-)NCBI
Cytogenetic Map6q21NCBI
NOVA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381426,443,090 - 26,598,033 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1426,443,090 - 26,598,033 (-)Ensemblhg38GRCh38
GRCh371426,912,296 - 27,067,239 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361425,984,929 - 26,136,800 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341426,009,163 - 26,136,800NCBI
Celera146,779,476 - 6,931,361 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef147,031,090 - 7,190,872 (-)NCBIHuRef
CHM1_11426,913,753 - 27,065,665 (-)NCBICHM1_1
T2T-CHM13v2.01420,640,973 - 20,795,930 (-)NCBIT2T-CHM13v2.0
Nova1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391246,744,678 - 46,866,143 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1246,741,300 - 46,865,712 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381246,697,895 - 46,819,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1246,694,517 - 46,818,929 (-)Ensemblmm10GRCm38
MGSCv371247,795,504 - 47,919,762 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361247,570,474 - 47,694,732 (-)NCBIMGSCv36mm8
Celera1248,021,874 - 48,146,837 (-)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1221.46NCBI
Nova1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540933,680,587 - 33,815,818 (+)Ensembl
ChiLan1.0NW_00495540933,681,947 - 33,820,356 (+)NCBIChiLan1.0ChiLan1.0
NOVA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21527,772,225 - 27,924,686 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11426,988,723 - 27,140,162 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0147,193,308 - 7,345,535 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11425,314,077 - 25,466,715 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1425,314,077 - 25,466,861 (-)EnsemblpanPan2panpan1.1
NOVA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.186,133,608 - 6,281,508 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl86,135,679 - 6,281,384 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha86,052,438 - 6,201,930 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.086,227,890 - 6,377,452 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl86,229,520 - 6,377,483 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.185,918,471 - 6,068,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.085,989,071 - 6,138,587 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.086,257,436 - 6,406,949 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nova1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864038,211,656 - 38,347,469 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364941,717,268 - 1,853,430 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364941,720,030 - 1,853,177 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOVA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl772,805,230 - 72,961,258 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1772,805,138 - 72,961,257 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2778,002,491 - 78,041,732 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NOVA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1243,363,652 - 3,513,901 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl243,360,831 - 3,514,435 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603615,126,163 - 15,276,533 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nova1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248205,821,477 - 5,971,637 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248205,821,232 - 5,973,709 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nova1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1760,574,357 - 60,699,951 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nova1
868 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:117
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000050372
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
NOVA1__6065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2663,783,483 - 63,784,096 (+)MAPPERmRatBN7.2
Rnor_6.0666,963,505 - 66,964,117NCBIRnor6.0
Rnor_5.0676,538,754 - 76,539,366UniSTSRnor5.0
RGSC_v3.4666,196,851 - 66,197,463UniSTSRGSC3.4
Celera662,747,215 - 62,747,827UniSTS
Cytogenetic Map6q21UniSTS
Nova1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2663,785,955 - 63,786,495 (+)MAPPERmRatBN7.2
Rnor_6.0666,965,977 - 66,966,516NCBIRnor6.0
Rnor_5.0676,541,226 - 76,541,765UniSTSRnor5.0
RGSC_v3.4666,199,323 - 66,199,862UniSTSRGSC3.4
Celera662,749,687 - 62,750,226UniSTS
Cytogenetic Map6q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 11 67 164 91 90 59 85 59 6 341 184 10 143 78 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY033093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY262017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000050372   ⟹   ENSRNOP00000045624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl663,784,937 - 63,905,114 (-)Ensembl
Rnor_6.0 Ensembl666,965,377 - 67,084,234 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083277   ⟹   ENSRNOP00000069458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl669,506,983 - 69,631,084 (-)Ensembl
mRatBN7.2 Ensembl663,783,489 - 63,906,289 (-)Ensembl
Rnor_6.0 Ensembl666,963,510 - 67,085,390 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103119   ⟹   ENSRNOP00000082322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl663,784,937 - 63,906,289 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137443   ⟹   ENSRNOP00000109689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl669,506,983 - 69,631,928 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139436   ⟹   ENSRNOP00000103777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl669,506,983 - 69,632,437 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000170778   ⟹   ENSRNOP00000109714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl669,506,983 - 69,632,437 (-)Ensembl
RefSeq Acc Id: NM_001100541   ⟹   NP_001094011
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,506,983 - 69,632,437 (-)NCBI
mRatBN7.2663,780,105 - 63,905,567 (-)NCBI
Rnor_6.0666,963,510 - 67,085,390 (-)NCBI
Rnor_5.0676,535,375 - 76,660,962 (-)NCBI
Celera662,747,220 - 62,869,241 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001414916   ⟹   NP_001401845
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,506,983 - 69,632,437 (-)NCBI
mRatBN7.2663,780,105 - 63,905,567 (-)NCBI
RefSeq Acc Id: NM_001414917   ⟹   NP_001401846
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,506,983 - 69,632,437 (-)NCBI
mRatBN7.2663,780,105 - 63,905,567 (-)NCBI
RefSeq Acc Id: XM_006240070   ⟹   XP_006240132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,632,134 (-)NCBI
mRatBN7.2663,780,105 - 63,905,268 (-)NCBI
Rnor_6.0666,960,126 - 67,085,131 (-)NCBI
Rnor_5.0676,535,375 - 76,660,962 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111963   ⟹   XP_038967891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,631,639 (-)NCBI
mRatBN7.2663,780,105 - 63,904,586 (-)NCBI
RefSeq Acc Id: XM_039111964   ⟹   XP_038967892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,632,134 (-)NCBI
mRatBN7.2663,780,105 - 63,905,269 (-)NCBI
RefSeq Acc Id: XM_039111966   ⟹   XP_038967894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,630,681 (-)NCBI
mRatBN7.2663,780,105 - 63,903,807 (-)NCBI
RefSeq Acc Id: XM_039111967   ⟹   XP_038967895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,630,662 (-)NCBI
mRatBN7.2663,780,105 - 63,903,779 (-)NCBI
RefSeq Acc Id: XM_063261663   ⟹   XP_063117733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,631,639 (-)NCBI
RefSeq Acc Id: XM_063261664   ⟹   XP_063117734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,540,358 (-)NCBI
RefSeq Acc Id: XM_063261665   ⟹   XP_063117735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,513,551 - 69,632,416 (-)NCBI
RefSeq Acc Id: NP_001094011   ⟸   NM_001100541
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL),   A6HBF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240132   ⟸   XM_006240070
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL),   D4AAF8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069458   ⟸   ENSRNOT00000083277
Ensembl Acc Id: ENSRNOP00000045624   ⟸   ENSRNOT00000050372
RefSeq Acc Id: XP_038967892   ⟸   XM_039111964
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967891   ⟸   XM_039111963
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967894   ⟸   XM_039111966
- Peptide Label: isoform X6
- UniProtKB: A6HBF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967895   ⟸   XM_039111967
- Peptide Label: isoform X6
- UniProtKB: A6HBF7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082322   ⟸   ENSRNOT00000103119
RefSeq Acc Id: NP_001401845   ⟸   NM_001414916
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL),   A0A8I6G9C1 (UniProtKB/TrEMBL),   A6HBF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401846   ⟸   NM_001414917
- Peptide Label: isoform 3
- UniProtKB: A6HBF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117733   ⟸   XM_063261663
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117734   ⟸   XM_063261664
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117735   ⟸   XM_063261665
- Peptide Label: isoform X7
- UniProtKB: A6HBF8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109689   ⟸   ENSRNOT00000137443
Ensembl Acc Id: ENSRNOP00000109714   ⟸   ENSRNOT00000170778
Ensembl Acc Id: ENSRNOP00000103777   ⟸   ENSRNOT00000139436
Protein Domains
K Homology   KH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80WA4-F1-model_v2 AlphaFold Q80WA4 1-474 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621345 AgrOrtholog
BioCyc Gene G2FUF-37657 BioCyc
Ensembl Genes ENSRNOG00000031440 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000083277 ENTREZGENE
  ENSRNOT00000137443 ENTREZGENE
  ENSRNOT00000139436 ENTREZGENE
  ENSRNOT00000170778 ENTREZGENE
Gene3D-CATH 3.30.1370.10 UniProtKB/Swiss-Prot
InterPro KH-I_NOVA_rpt1 UniProtKB/Swiss-Prot
  KH-I_NOVA_rpt2 UniProtKB/Swiss-Prot
  KH-I_NOVA_rpt3 UniProtKB/Swiss-Prot
  KH_dom UniProtKB/Swiss-Prot
  KH_dom_type_1 UniProtKB/Swiss-Prot
  KH_dom_type_1_sf UniProtKB/Swiss-Prot
NCBI Gene Nova1 ENTREZGENE
PANTHER KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam KH_1 UniProtKB/Swiss-Prot
PhenoGen Nova1 PhenoGen
PROSITE KH_TYPE_1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031440 RatGTEx
SMART SM00322 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54791 UniProtKB/Swiss-Prot
UniProt A0A0G2JVE8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G9C1 ENTREZGENE
  A0ABK0LEK4_RAT UniProtKB/TrEMBL
  A0ABK0LU44_RAT UniProtKB/TrEMBL
  A0ABK0M390_RAT UniProtKB/TrEMBL
  A6HBF5 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF6 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF7 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF8 ENTREZGENE, UniProtKB/TrEMBL
  D4AAF8 ENTREZGENE
  NOVA1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-12 Nova1  NOVA alternative splicing regulator 1  Nova1  neuro-oncological ventral antigen 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Nova1  neuro-oncological ventral antigen 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Nova1  neuro-oncological ventral antigen 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript has three splice variant isoforms 708602