Cntn1 (contactin 1) - Rat Genome Database

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Pathways
Gene: Cntn1 (contactin 1) Rattus norvegicus
Analyze
Symbol: Cntn1
Name: contactin 1
RGD ID: 621300
Description: Predicted to enable carbohydrate binding activity and cell-cell adhesion mediator activity. Predicted to be involved in cell-cell adhesion; locomotory behavior; and nervous system development. Predicted to act upstream of or within several processes, including nervous system development; positive regulation of neuron projection development; and positive regulation of sodium ion transport. Predicted to be located in side of membrane. Predicted to be active in axon; glutamatergic synapse; and synaptic membrane. Human ortholog(s) of this gene implicated in Compton-North congenital myopathy. Orthologous to human CNTN1 (contactin 1); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: contactin-1; F3; neural cell surface protein F3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87125,142,638 - 125,440,397 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7125,142,696 - 125,440,391 (+)EnsemblGRCr8
mRatBN7.27123,263,146 - 123,560,896 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7123,372,792 - 123,558,541 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7125,146,295 - 125,332,781 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07127,372,157 - 127,558,628 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07127,293,669 - 127,480,412 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07133,290,606 - 133,588,314 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7133,400,485 - 133,586,677 (+)Ensemblrn6Rnor6.0
Rnor_5.07132,976,416 - 133,272,747 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47130,658,836 - 130,845,071 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7119,777,077 - 119,962,153 (+)NCBICelera
RGSC_v3.17130,735,272 - 130,921,508 (+)NCBI
Cytogenetic Map7q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3',5'-cyclic AMP  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
atrazine  (ISO)
Azoxymethane  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
Cuprizon  (EXP)
deguelin  (ISO)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diethyl maleate  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
lead(0)  (ISO)
Mecamylamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
progesterone  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tubocurarine  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IBA)
glutamatergic synapse  (IEA,ISO)
membrane  (IEA)
plasma membrane  (IBA,IEA,TAS)
postsynaptic membrane  (IEA,ISO)
presynaptic membrane  (IEA,ISO)
side of membrane  (IEA)
synapse  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Berglund EO and Ranscht B, Genomics 1994 Jun;21(3):571-82.
2. Ataxia and abnormal cerebellar microorganization in mice with ablated contactin gene expression. Berglund EO, etal., Neuron 1999 Nov;24(3):739-50.
3. Transcriptional changes in adhesion-related genes are site-specific during noise-induced cochlear pathogenesis. Cai Q, etal., Neurobiol Dis. 2012 Feb;45(2):723-32. Epub 2011 Oct 25.
4. Regulatory mechanisms that mediate tenascin C-dependent inhibition of oligodendrocyte precursor differentiation. Czopka T, etal., J Neurosci. 2010 Sep 15;30(37):12310-22.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Developmental expression of the neural adhesion molecule F3 in the rat brain. Hosoya H, etal., Neurosci Lett 1995 Feb 17;186(2-3):83-6.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1. Poliak S, etal., J Cell Biol. 2003 Sep 15;162(6):1149-60. Epub 2003 Sep 8.
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Soluble forms of NCAM and F3 neuronal cell adhesion molecules promote Schwann cell migration: identification of protein tyrosine phosphatases zeta/beta as the putative F3 receptors on Schwann cells. Thomaidou D, etal., J Neurochem. 2001 Aug;78(4):767-78.
Additional References at PubMed
PMID:1729438   PMID:7628014   PMID:9081628   PMID:9118959   PMID:15967539   PMID:16029194   PMID:17634366   PMID:18354028   PMID:19026398   PMID:19458237   PMID:20451518   PMID:23376485  
PMID:23533145   PMID:29476059  


Genomics

Comparative Map Data
Cntn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87125,142,638 - 125,440,397 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7125,142,696 - 125,440,391 (+)EnsemblGRCr8
mRatBN7.27123,263,146 - 123,560,896 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7123,372,792 - 123,558,541 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7125,146,295 - 125,332,781 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07127,372,157 - 127,558,628 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07127,293,669 - 127,480,412 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07133,290,606 - 133,588,314 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7133,400,485 - 133,586,677 (+)Ensemblrn6Rnor6.0
Rnor_5.07132,976,416 - 133,272,747 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47130,658,836 - 130,845,071 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7119,777,077 - 119,962,153 (+)NCBICelera
RGSC_v3.17130,735,272 - 130,921,508 (+)NCBI
Cytogenetic Map7q35NCBI
CNTN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381240,692,439 - 41,072,415 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1240,692,431 - 41,072,415 (+)Ensemblhg38GRCh38
GRCh371241,086,241 - 41,466,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361239,372,625 - 39,750,361 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341239,372,624 - 39,750,361NCBI
Celera1239,889,695 - 40,267,406 (+)NCBICelera
Cytogenetic Map12q12NCBI
HuRef1238,112,937 - 38,492,512 (+)NCBIHuRef
CHM1_11241,051,536 - 41,431,091 (+)NCBICHM1_1
T2T-CHM13v2.01240,652,132 - 41,031,590 (+)NCBIT2T-CHM13v2.0
Cntn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391591,949,034 - 92,239,834 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1591,949,046 - 92,239,848 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381592,051,152 - 92,341,967 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1592,051,165 - 92,341,967 (+)Ensemblmm10GRCm38
MGSCv371591,881,596 - 92,172,398 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361591,956,372 - 92,168,291 (+)NCBIMGSCv36mm8
Celera1594,177,246 - 94,486,845 (+)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1546.39NCBI
Cntn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955500245,896 - 540,600 (+)Ensembl
ChiLan1.0NW_004955500154,704 - 540,546 (+)NCBIChiLan1.0ChiLan1.0
CNTN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21053,073,079 - 53,457,589 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11253,069,840 - 53,454,351 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01247,630,295 - 48,014,766 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11248,492,558 - 48,877,396 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1248,492,564 - 48,670,126 (-)EnsemblpanPan2panpan1.1
CNTN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12712,655,021 - 13,005,536 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2712,657,287 - 12,920,315 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2733,445,834 - 33,709,949 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02712,856,273 - 13,206,411 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2712,856,279 - 13,206,379 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12712,671,345 - 12,901,312 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02712,704,418 - 13,054,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02733,541,381 - 33,890,677 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cntn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494573,184,782 - 73,458,579 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493660723,150 - 292,013 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366078,430 - 291,964 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNTN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl572,168,511 - 72,495,633 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1572,168,496 - 72,495,454 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2575,140,748 - 75,389,289 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNTN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11136,950,020 - 37,332,058 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1137,167,079 - 37,333,314 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037209,407,722 - 209,806,565 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cntn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624917471,837 - 750,245 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624917292,404 - 752,017 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cntn1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11265,059,033 - 265,350,082 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cntn1
2511 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:93
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000006219
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7118556868125929417Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat

Markers in Region
D7Got118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27123,408,244 - 123,408,521 (+)MAPPERmRatBN7.2
Rnor_6.07133,435,313 - 133,435,589NCBIRnor6.0
Rnor_5.07133,119,880 - 133,120,156UniSTSRnor5.0
RGSC_v3.47130,694,295 - 130,694,572RGDRGSC3.4
RGSC_v3.47130,694,296 - 130,694,572UniSTSRGSC3.4
Celera7119,812,135 - 119,812,405UniSTS
RGSC_v3.17130,770,733 - 130,771,009RGD
RH 3.4 Map71020.3UniSTS
RH 3.4 Map71020.3RGD
RH 2.0 Map7745.3RGD
Cytogenetic Map7q35UniSTS
Cntn1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87125,438,333 - 125,438,491 (+)Marker Load Pipeline
mRatBN7.27123,558,833 - 123,558,990 (+)MAPPERmRatBN7.2
Rnor_6.07133,586,252 - 133,586,408NCBIRnor6.0
Rnor_5.07133,270,685 - 133,270,841UniSTSRnor5.0
RGSC_v3.47130,845,364 - 130,845,520UniSTSRGSC3.4
Celera7119,962,446 - 119,962,602UniSTS
Cytogenetic Map7q35UniSTS
BF415915  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27123,498,537 - 123,498,674 (+)MAPPERmRatBN7.2
Rnor_6.07133,526,038 - 133,526,174NCBIRnor6.0
Rnor_5.07133,210,471 - 133,210,607UniSTSRnor5.0
RGSC_v3.47130,783,937 - 130,784,073UniSTSRGSC3.4
Celera7119,902,121 - 119,902,257UniSTS
RH 3.4 Map71009.8UniSTS
Cytogenetic Map7q35UniSTS
AU048466  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27123,408,225 - 123,408,497 (+)MAPPERmRatBN7.2
Rnor_6.07133,435,294 - 133,435,565NCBIRnor6.0
Rnor_5.07133,119,861 - 133,120,132UniSTSRnor5.0
RGSC_v3.47130,694,277 - 130,694,548UniSTSRGSC3.4
Celera7119,812,116 - 119,812,381UniSTS
Cytogenetic Map7q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 165 89 88 57 58 57 6 310 157 11 140 72 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001439869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_057118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ877233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ877234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ877235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ877236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ877237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000006219   ⟹   ENSRNOP00000006219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7125,320,861 - 125,408,809 (+)Ensembl
mRatBN7.2 Ensembl7123,372,792 - 123,558,541 (+)Ensembl
Rnor_6.0 Ensembl7133,400,485 - 133,585,959 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080621   ⟹   ENSRNOP00000071355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7123,441,350 - 123,529,306 (+)Ensembl
Rnor_6.0 Ensembl7133,457,255 - 133,586,677 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120797   ⟹   ENSRNOP00000098410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7125,142,696 - 125,440,391 (+)Ensembl
RefSeq Acc Id: NM_057118   ⟹   NP_476459
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,252,310 - 125,438,042 (+)NCBI
mRatBN7.27123,372,792 - 123,558,541 (+)NCBI
Rnor_6.07133,400,485 - 133,585,959 (+)NCBI
Rnor_5.07132,976,416 - 133,272,747 (+)NCBI
RGSC_v3.47130,658,836 - 130,845,071 (+)RGD
Celera7119,777,077 - 119,962,153 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242177   ⟹   XP_006242239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,251,891 - 125,440,397 (+)NCBI
mRatBN7.27123,404,063 - 123,560,896 (+)NCBI
Rnor_6.07133,399,891 - 133,588,314 (+)NCBI
Rnor_5.07132,976,416 - 133,272,747 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765659   ⟹   XP_008763881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,664 - 125,378,244 (+)NCBI
mRatBN7.27123,263,146 - 123,499,462 (+)NCBI
Rnor_6.07133,290,606 - 133,526,962 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594616   ⟹   XP_017450105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,638 - 125,440,397 (+)NCBI
mRatBN7.27123,263,146 - 123,560,896 (+)NCBI
Rnor_6.07133,290,606 - 133,588,314 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078298   ⟹   XP_038934226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,440,397 (+)NCBI
mRatBN7.27123,263,146 - 123,560,896 (+)NCBI
RefSeq Acc Id: XM_063262899   ⟹   XP_063118969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,440,397 (+)NCBI
RefSeq Acc Id: XM_063262900   ⟹   XP_063118970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,306,208 - 125,440,397 (+)NCBI
RefSeq Acc Id: XM_063262901   ⟹   XP_063118971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,440,397 (+)NCBI
RefSeq Acc Id: XM_063262902   ⟹   XP_063118972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,440,397 (+)NCBI
RefSeq Acc Id: XM_063262903   ⟹   XP_063118973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,251,709 - 125,378,244 (+)NCBI
RefSeq Acc Id: XM_063262904   ⟹   XP_063118974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,378,244 (+)NCBI
RefSeq Acc Id: XM_063262905   ⟹   XP_063118975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,378,244 (+)NCBI
RefSeq Acc Id: XM_063262906   ⟹   XP_063118976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,251,886 - 125,378,244 (+)NCBI
RefSeq Acc Id: XM_063262907   ⟹   XP_063118977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,142,672 - 125,378,244 (+)NCBI
RefSeq Acc Id: XM_063262908   ⟹   XP_063118978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87125,201,698 - 125,378,244 (+)NCBI
RefSeq Acc Id: NP_476459   ⟸   NM_057118
- Peptide Label: precursor
- UniProtKB: Q63198 (UniProtKB/Swiss-Prot),   A6K7R9 (UniProtKB/TrEMBL),   A0A8L2R3Y6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242239   ⟸   XM_006242177
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008763881   ⟸   XM_008765659
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017450105   ⟸   XM_017594616
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000006219   ⟸   ENSRNOT00000006219
Ensembl Acc Id: ENSRNOP00000071355   ⟸   ENSRNOT00000080621
RefSeq Acc Id: XP_038934226   ⟸   XM_039078298
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118969   ⟸   XM_063262899
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118972   ⟸   XM_063262902
- Peptide Label: isoform X1
- UniProtKB: Q63198 (UniProtKB/Swiss-Prot),   A6K7R9 (UniProtKB/TrEMBL),   A0A8L2R3Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118971   ⟸   XM_063262901
- Peptide Label: isoform X1
- UniProtKB: Q63198 (UniProtKB/Swiss-Prot),   A6K7R9 (UniProtKB/TrEMBL),   A0A8L2R3Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118974   ⟸   XM_063262904
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118977   ⟸   XM_063262907
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118975   ⟸   XM_063262905
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118978   ⟸   XM_063262908
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118973   ⟸   XM_063262903
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118976   ⟸   XM_063262906
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118970   ⟸   XM_063262900
- Peptide Label: isoform X1
- UniProtKB: Q63198 (UniProtKB/Swiss-Prot),   A6K7R9 (UniProtKB/TrEMBL),   A0A8L2R3Y6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000098410   ⟸   ENSRNOT00000120797
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63198-F1-model_v2 AlphaFold Q63198 1-1021 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621300 AgrOrtholog
BioCyc Gene G2FUF-32360 BioCyc
Ensembl Genes ENSRNOG00000004438 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006219 ENTREZGENE
  ENSRNOT00000006219.5 UniProtKB/Swiss-Prot
  ENSRNOT00000120797 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Contactin-1 UniProtKB/Swiss-Prot
  Contactin-1_2_Ig1 UniProtKB/Swiss-Prot
  Contactin-1_Ig3 UniProtKB/Swiss-Prot
  Contactin-1_Ig6 UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
KEGG Report rno:117258 UniProtKB/Swiss-Prot
NCBI Gene 117258 ENTREZGENE
PANTHER PROTEIN SIDEKICK UniProtKB/Swiss-Prot
  PTHR44170:SF10 UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
  I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
  PF00047 UniProtKB/Swiss-Prot
PhenoGen Cntn1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004438 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
  IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8L2R3Y6 ENTREZGENE
  A6K7R9 ENTREZGENE, UniProtKB/TrEMBL
  CNTN1_RAT UniProtKB/Swiss-Prot
  Q53I74_RAT UniProtKB/TrEMBL
  Q63198 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Cntn1  contactin 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cntn1  contactin 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology 99% amino acid identity with mouse homolog 728268
gene_protein 1021 amino acids 728268