Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gripap1 | Rat | 1,2-dichloroethane | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of GRIPAP1 mRNA | CTD | PMID:28960355 | Gripap1 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Gripap1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of GRIPAP1 mRNA | CTD | PMID:22206623 | Gripap1 | Rat | 17beta-estradiol | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | Estradiol results in increased expression of GRIPAP1 mRNA | CTD | PMID:39298647 | Gripap1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gripap1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GRIPAP1 mRNA | CTD | PMID:21570461 | Gripap1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of GRIPAP1 mRNA | CTD | PMID:21346803 | Gripap1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of GRIPAP1 mRNA | CTD | PMID:30851411 | Gripap1 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GRIPAP1 mRNA | CTD | PMID:20188158 | Gripap1 | Rat | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin analog results in decreased expression of GRIPAP1 protein | CTD | PMID:26597043 | Gripap1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Gripap1 | Rat | aflatoxin B1 | decreases methylation | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of GRIPAP1 intron | CTD | PMID:30157460 | Gripap1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of GRIPAP1 mRNA | CTD | PMID:16483693 | Gripap1 | Rat | aristolochic acid A | increases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of GRIPAP1 mRNA | CTD | PMID:33212167 | Gripap1 | Rat | arsane | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Gripap1 | Rat | arsenic atom | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Gripap1 | Rat | benzo[a]pyrene | affects methylation | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GRIPAP1 exon; Benzo(a)pyrene affects the methylation of GRIPAP1 promoter | CTD | PMID:27901495 | Gripap1 | Rat | bisphenol A | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of GRIPAP1 mRNA | CTD | PMID:26063408 | Gripap1 | Rat | bisphenol A | affects splicing | ISO | Gripap1 (Mus musculus) | 6480464 | bisphenol A affects the splicing of GRIPAP1 mRNA | CTD | PMID:37894381 | Gripap1 | Rat | bisphenol A | decreases expression | ISO | Gripap1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of GRIPAP1 mRNA | CTD | PMID:33221593 | Gripap1 | Rat | bisphenol A | decreases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GRIPAP1 protein | CTD | PMID:33376534 | Gripap1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GRIPAP1 mRNA | CTD | PMID:30816183|PMID:32528016|PMID:33296240|PMID:34947998 | Gripap1 | Rat | bisphenol A | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GRIPAP1 gene; [INS protein co-treated more ... | CTD | PMID:28628672|PMID:31601247 | Gripap1 | Rat | caffeine | decreases phosphorylation | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of GRIPAP1 protein | CTD | PMID:35688186 | Gripap1 | Rat | choline | multiple interactions | ISO | Gripap1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ... | CTD | PMID:20938992 | Gripap1 | Rat | chrysene | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | chrysene results in increased expression of GRIPAP1 mRNA | CTD | PMID:26377693 | Gripap1 | Rat | crocidolite asbestos | decreases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in decreased expression of GRIPAP1 mRNA | CTD | PMID:29523930 | Gripap1 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of GRIPAP1 mRNA | CTD | PMID:23640034 | Gripap1 | Rat | dexamethasone | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Gripap1 | Rat | Dibutyl phosphate | affects expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GRIPAP1 mRNA | CTD | PMID:37042841 | Gripap1 | Rat | enzyme inhibitor | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Gripap1 | Rat | epoxiconazole | decreases expression | ISO | Gripap1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of GRIPAP1 mRNA | CTD | PMID:35436446 | Gripap1 | Rat | ethanol | multiple interactions | EXP | | 6480464 | N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid inhibits the reaction [Ethanol results in increased expression of GRIPAP1 mRNA] | CTD | PMID:20655511 | Gripap1 | Rat | ethanol | affects splicing | ISO | Gripap1 (Mus musculus) | 6480464 | Ethanol affects the splicing of GRIPAP1 mRNA | CTD | PMID:30319688 | Gripap1 | Rat | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of GRIPAP1 mRNA | CTD | PMID:20655511 | Gripap1 | Rat | folic acid | multiple interactions | ISO | Gripap1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ... | CTD | PMID:20938992 | Gripap1 | Rat | FR900359 | decreases phosphorylation | ISO | GRIPAP1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of GRIPAP1 protein | CTD | PMID:37730182 | Gripap1 | Rat | fulvestrant | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GRIPAP1 gene | CTD | PMID:31601247 | Gripap1 | Rat | indometacin | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Gripap1 | Rat | ivermectin | decreases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of GRIPAP1 protein | CTD | PMID:32959892 | Gripap1 | Rat | L-methionine | multiple interactions | ISO | Gripap1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ... | CTD | PMID:20938992 | Gripap1 | Rat | manganese atom | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Gripap1 | Rat | manganese(0) | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Gripap1 | Rat | manganese(II) chloride | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Gripap1 | Rat | methamphetamine | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of GRIPAP1 mRNA | CTD | PMID:26307267 | Gripap1 | Rat | ozone | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of GRIPAP1 mRNA | CTD | PMID:35430440 | Gripap1 | Rat | rac-lactic acid | decreases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of GRIPAP1 mRNA | CTD | PMID:30851411 | Gripap1 | Rat | resveratrol | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GRIPAP1 mRNA | CTD | PMID:23557933 | Gripap1 | Rat | rotenone | decreases expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of GRIPAP1 protein | CTD | PMID:39603559 | Gripap1 | Rat | sodium arsenite | multiple interactions | ISO | GRIPAP1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Gripap1 | Rat | triphenyl phosphate | affects expression | ISO | GRIPAP1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GRIPAP1 mRNA | CTD | PMID:37042841 | Gripap1 | Rat | triptonide | increases expression | ISO | Gripap1 (Mus musculus) | 6480464 | triptonide results in increased expression of GRIPAP1 mRNA | CTD | PMID:33045310 | Gripap1 | Rat | tungsten | decreases expression | ISO | Gripap1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of GRIPAP1 mRNA | CTD | PMID:30912803 | Gripap1 | Rat | valproic acid | increases methylation | ISO | GRIPAP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of GRIPAP1 gene | CTD | PMID:29154799 | | 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