Serpina10 (serpin family A member 10) - Rat Genome Database

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Gene: Serpina10 (serpin family A member 10) Rattus norvegicus
Analyze
Symbol: Serpina10
Name: serpin family A member 10
RGD ID: 621220
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Involved in liver regeneration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in thrombophilia. Orthologous to human SERPINA10 (serpin family A member 10); PARTICIPATES IN coagulation cascade pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100909524; MGC108600; plasma protein associated with liver regeneration; protein Z-dependent protease inhibitor; protein Z-dependent protease inhibitor-like; PZ-dependent protease inhibitor; PZI; RASP-1; Rasp1; regeneration-associated serpin 1; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serpin A10; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serpin peptidase inhibitor, clade A, member 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,520,894 - 128,529,332 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6128,520,896 - 128,529,332 (-)EnsemblGRCr8
mRatBN7.26122,756,106 - 122,764,544 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,756,108 - 122,764,544 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6122,896,632 - 122,905,075 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06123,191,904 - 123,200,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,528,769 - 122,537,212 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,500,014 - 127,508,470 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,500,016 - 127,508,452 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl6129,004,240 - 129,010,271 (-)Ensemblrn6Rnor6.0
Rnor_5.06136,718,786 - 136,727,224 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46127,887,684 - 127,896,122 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6120,236,372 - 120,244,810 (-)NCBICelera
RGSC_v3.16127,891,432 - 127,899,869 (-)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amiodarone  (EXP,ISO)
ammonium chloride  (EXP)
aristolochic acid A  (EXP)
atrazine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diclofenac  (ISO)
endosulfan  (EXP)
fenthion  (ISO)
fipronil  (EXP)
flutamide  (EXP)
glafenine  (EXP)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
L-ethionine  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
Moniliformin  (ISO)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propanal  (ISO)
quartz  (EXP)
quercetin  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Protein Z, an anticoagulant protein with expanding role in reproductive biology. Almawi WY, etal., Reproduction. 2013 Jun 27;146(2):R73-80. doi: 10.1530/REP-13-0072. Print 2013 Aug.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Changes in gene expression in small bowel neuroendocrine tumors associated with progression to metastases. Keck KJ, etal., Surgery. 2018 Jan;163(1):232-239. doi: 10.1016/j.surg.2017.07.031. Epub 2017 Nov 16.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. cDNA cloning of rasp-1, a novel gene encoding a plasma protein associated with liver regeneration. New L, etal., Biochem Biophys Res Commun 1996 Jun 14;223(2):404-12.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia. Water N, etal., Br J Haematol. 2004 Oct;127(2):190-4.
12. Prothrombotic phenotype of protein Z deficiency. Yin ZF, etal., Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6734-8.
Additional References at PubMed
PMID:11751269   PMID:12477932   PMID:15489334   PMID:23533145  


Genomics

Comparative Map Data
Serpina10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,520,894 - 128,529,332 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6128,520,896 - 128,529,332 (-)EnsemblGRCr8
mRatBN7.26122,756,106 - 122,764,544 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,756,108 - 122,764,544 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6122,896,632 - 122,905,075 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06123,191,904 - 123,200,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,528,769 - 122,537,212 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,500,014 - 127,508,470 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,500,016 - 127,508,452 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl6129,004,240 - 129,010,271 (-)Ensemblrn6Rnor6.0
Rnor_5.06136,718,786 - 136,727,224 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46127,887,684 - 127,896,122 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6120,236,372 - 120,244,810 (-)NCBICelera
RGSC_v3.16127,891,432 - 127,899,869 (-)NCBI
Cytogenetic Map6q32NCBI
SERPINA10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,280,460 - 94,293,268 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,278,767 - 94,293,295 (-)Ensemblhg38GRCh38
GRCh371494,746,797 - 94,759,605 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361493,819,403 - 93,829,349 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341493,819,404 - 93,829,114NCBI
Celera1474,803,423 - 74,813,369 (-)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1474,929,448 - 74,939,406 (-)NCBIHuRef
CHM1_11494,687,457 - 94,697,415 (-)NCBICHM1_1
T2T-CHM13v2.01488,507,743 - 88,520,553 (-)NCBIT2T-CHM13v2.0
Serpina10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912103,582,934 - 103,597,681 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12103,581,045 - 103,597,703 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812103,616,675 - 103,631,490 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12103,614,786 - 103,631,444 (-)Ensemblmm10GRCm38
MGSCv3712104,854,885 - 104,869,615 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612104,017,725 - 104,032,455 (-)NCBIMGSCv36mm8
Celera12104,832,950 - 104,847,686 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1252.97NCBI
Serpina10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543816,335,544 - 16,345,094 (-)Ensembl
ChiLan1.0NW_00495543816,335,201 - 16,345,093 (-)NCBIChiLan1.0ChiLan1.0
SERPINA10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21595,441,471 - 95,448,088 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11494,656,249 - 94,664,593 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01474,914,680 - 74,927,325 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11494,248,362 - 94,258,301 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1494,248,362 - 94,257,835 (-)EnsemblpanPan2panpan1.1
Serpina10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864011,337,053 - 11,345,124 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367332,121,875 - 2,129,988 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINA10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12472,059,523 - 72,069,989 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2472,058,780 - 72,069,085 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605359,292,823 - 59,299,933 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serpina10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473410,620,620 - 10,631,306 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473410,619,044 - 10,630,963 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Serpina10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17114,890,414 - 114,898,871 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Serpina10
48 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000073709, ENSRNOT00000075378
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
18 1 10 50 128 129 108 48 108 4 262 74 2 39 62 45 21 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000073709   ⟹   ENSRNOP00000064104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,520,896 - 128,529,332 (-)Ensembl
mRatBN7.2 Ensembl6122,756,108 - 122,764,544 (-)Ensembl
Rnor_6.0 Ensembl6127,500,016 - 127,508,452 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075378   ⟹   ENSRNOP00000066602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6129,004,240 - 129,010,271 (-)Ensembl
RefSeq Acc Id: NM_133617   ⟹   NP_598301
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,520,894 - 128,529,332 (-)NCBI
mRatBN7.26122,756,106 - 122,764,544 (-)NCBI
Rnor_6.06127,500,014 - 127,508,452 (-)NCBI
Rnor_5.06136,718,786 - 136,727,224 (-)NCBI
RGSC_v3.46127,887,684 - 127,896,122 (-)RGD
Celera6120,236,372 - 120,244,810 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_598301 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52624 (Get FASTA)   NCBI Sequence Viewer  
  AAH88113 (Get FASTA)   NCBI Sequence Viewer  
  EDL81781 (Get FASTA)   NCBI Sequence Viewer  
  EDL81782 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064104
  ENSRNOP00000064104.1
GenBank Protein Q62975 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_598301   ⟸   NM_133617
- Peptide Label: precursor
- UniProtKB: Q5M8C2 (UniProtKB/Swiss-Prot),   Q62975 (UniProtKB/Swiss-Prot),   A6JEN8 (UniProtKB/TrEMBL),   A6JEN7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064104   ⟸   ENSRNOT00000073709
Ensembl Acc Id: ENSRNOP00000066602   ⟸   ENSRNOT00000075378
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62975-F1-model_v2 AlphaFold Q62975 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694797
Promoter ID:EPDNEW_R5321
Type:initiation region
Name:Serpina10_1
Description:serpin family A member 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06127,508,403 - 127,508,463EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621220 AgrOrtholog
BioCyc Gene G2FUF-36407 BioCyc
Ensembl Genes ENSRNOG00000048988 Ensembl
  ENSRNOG00000050761 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000073709 ENTREZGENE
  ENSRNOT00000073709.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot
  3.30.497.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7326099 IMAGE-MGC_LOAD
InterPro PZI_serpin_dom UniProtKB/Swiss-Prot
  Serpin_dom UniProtKB/Swiss-Prot
  Serpin_fam UniProtKB/Swiss-Prot
  Serpin_sf UniProtKB/Swiss-Prot
  Serpin_sf_1 UniProtKB/Swiss-Prot
  Serpin_sf_2 UniProtKB/Swiss-Prot
KEGG Report rno:171154 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108600 IMAGE-MGC_LOAD
NCBI Gene 171154 ENTREZGENE
PANTHER PROTEIN Z-DEPENDENT PROTEASE INHIBITOR UniProtKB/Swiss-Prot
  PTHR11461 UniProtKB/Swiss-Prot
Pfam Serpin UniProtKB/Swiss-Prot
PhenoGen Serpina10 PhenoGen
PRINTS LEUSERPINII UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000048988 RatGTEx
  ENSRNOG00000050761 RatGTEx
SMART SERPIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot
UniProt A6JEN7 ENTREZGENE, UniProtKB/TrEMBL
  A6JEN8 ENTREZGENE, UniProtKB/TrEMBL
  Q5M8C2 ENTREZGENE
  Q62975 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q5M8C2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Serpina10  serpin family A member 10  LOC100909524  protein Z-dependent protease inhibitor-like  Data merged from RGD:6503444 737654 PROVISIONAL
2016-04-13 Serpina10  serpin family A member 10  Serpina10  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Serpina10  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10  Serpina10  serpin peptidase inhibitor, clade A, member 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909524  protein Z-dependent protease inhibitor-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-03-05 Serpina10  serpin peptidase inhibitor, clade A, member 10  Serpina10  serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Serpina10  serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10    serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10  Name updated 1299863 APPROVED
2004-09-10 Serpina10  serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Serpina10  serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA is highly expressed in liver and displays increased expession during liver regeneration 729731