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Gene: Rpl15 (ribosomal protein L15) Rattus norvegicus

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Symbol:

Rpl15

Name:

ribosomal protein L15

RGD ID:

621181

Description:

Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in response to ethanol. Located in A band. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 12. Orthologous to human RPL15 (ribosomal protein L15); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

60S ribosomal protein L15; large ribosomal subunit protein eL15; Rpl10

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RPL15 (ribosomal protein L15)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rpl15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rpl15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RPL15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RPL15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rpl15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RPL15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RPL15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rpl15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rpl15 (ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ALDH9A1 (aldehyde dehydrogenase 9 family member A1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RPL15 (ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RPL15 (ribosomal protein L15)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rpl15 (ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rpl15 (ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rpl15 (ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpl-15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPL15A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPL15B	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RpL15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rpl15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	rpl15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	9,934,663 - 9,937,946 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	9,934,679 - 9,938,308 (+)	Ensembl				GRCr8
mRatBN7.2	15	7,503,883 - 7,507,166 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	10,227,171 - 10,228,000 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	15	7,503,883 - 7,507,165 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	9,649,553 - 9,652,826 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	10,562,350 - 10,565,623 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	8,862,768 - 8,866,041 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	8,188,717 - 8,192,153 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	8,189,253 - 8,192,152 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	12,250,776 - 12,254,212 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	9,082,190 - 9,085,473 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	7,557,178 - 7,560,461 (+)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Diamond-Blackfan anemia 12 (ISO)

Disease Progression (ISO)

Stomach Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

2,6-dinitrotoluene (EXP)

2-nitrofluorene (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP)

4-hydroxyphenyl retinamide (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (ISO)

acrolein (ISO)

aflatoxin B1 (EXP)

alpha-pinene (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzbromarone (EXP)

benzene-1,2,4-triol (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (EXP)

bromobenzene (EXP)

cannabidiol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chloropicrin (ISO)

chromium(6+) (ISO)

clofibrate (EXP,ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cylindrospermopsin (ISO)

cypermethrin (ISO)

deoxynivalenol (ISO)

diethylstilbestrol (EXP,ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

enzyme inhibitor (ISO)

flavonoids (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

furfural (ISO)

inulin (ISO)

ivermectin (ISO)

L-ethionine (EXP)

Mesaconitine (EXP)

methamphetamine (ISO)

methapyrilene (EXP)

methidathion (ISO)

methylmercury chloride (ISO)

miconazole (ISO)

N-nitrosodimethylamine (EXP)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

omeprazole (EXP)

ozone (EXP,ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

piperonyl butoxide (EXP)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

quercetin (ISO)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sunitinib (ISO)

thioacetamide (EXP)

tolcapone (EXP)

triphenyl phosphate (ISO)

uranium atom (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoplasmic translation (IBA,ISO)

response to ethanol (IEP)

translation (IEA)

Cellular Component

A band (IDA)

cytoplasm (IEA,ISO)

cytosolic large ribosomal subunit (IBA,IDA,ISO)

cytosolic ribosome (IEA,ISO)

nucleus (ISO)

ribonucleoprotein complex (IEA)

ribosomal subunit (IEA)

ribosome (IEA)

synapse (ISO)

Molecular Function

protein binding (ISO)

RNA binding (IBA)

structural constituent of ribosome (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (ISO)

translation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Structures of the human and Drosophila 80S ribosome.	Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2.	The primary structure of rat ribosomal protein L15.	Chang YL, etal., Biochem Biophys Res Commun 1994 May 30;201(1):108-14.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Effect of ethanol on hepatic ribosomal proteins and mRNA.	Haviryaji KS, etal., Mol Cell Biochem. 1992 Oct 7;115(2):143-7.
5.	An overview of pre-ribosomal RNA processing in eukaryotes.	Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
6.	Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution.	Horne Z and Hesketh J, Biochem J. 1990 May 15;268(1):231-6.
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation
13.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.	Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'.	Tsurugi K, etal., J Biol Chem. 1977 Jun 10;252(11):3961-9.

Additional References at PubMed

PMID:7667285	PMID:12962325	PMID:15489334	PMID:21630459	PMID:22658674	PMID:22681889	PMID:23376485	PMID:25468996	PMID:30053369

Genomics

Comparative Map Data

Rpl15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	9,934,663 - 9,937,946 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	9,934,679 - 9,938,308 (+)	Ensembl				GRCr8
mRatBN7.2	15	7,503,883 - 7,507,166 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	10,227,171 - 10,228,000 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	15	7,503,883 - 7,507,165 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	9,649,553 - 9,652,826 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	10,562,350 - 10,565,623 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	8,862,768 - 8,866,041 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	8,188,717 - 8,192,153 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	8,189,253 - 8,192,152 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	12,250,776 - 12,254,212 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	9,082,190 - 9,085,473 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	7,557,178 - 7,560,461 (+)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

RPL15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	23,916,545 - 23,924,631 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	23,916,591 - 23,924,374 (+)	Ensembl			hg38	GRCh38
GRCh37	3	23,958,036 - 23,966,122 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	23,933,643 - 23,937,338 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	23,933,642 - 23,937,334	NCBI
Celera	3	23,894,829 - 23,898,524 (+)	NCBI		Celera
Cytogenetic Map	3	p24.2	NCBI
HuRef	3	23,904,389 - 23,911,124 (+)	NCBI		HuRef
CHM1_1	3	23,910,110 - 23,917,002 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	23,921,321 - 23,929,407 (+)	NCBI		T2T-CHM13v2.0

Rpl15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	4,198,710 - 4,201,873 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	4,198,305 - 4,201,873 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	18,267,823 - 18,270,986 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	18,267,823 - 18,271,391 (-)	Ensembl			mm10	GRCm38
MGSCv37	14	19,100,337 - 19,103,500 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	21,935,943 - 21,959,487 (-)	NCBI		MGSCv36	mm8
Celera	14	13,960,053 - 13,963,216 (-)	NCBI		Celera
Cytogenetic Map	14	A1	NCBI
cM Map	14	7.08	NCBI

Rpl15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	15,766,465 - 15,769,239 (+)	Ensembl
ChiLan1.0	NW_004955430	15,766,465 - 15,769,239 (+)	NCBI	ChiLan1.0	ChiLan1.0

RPL15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	23,877,684 - 23,880,508 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	23,882,529 - 23,885,280 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	23,829,041 - 23,832,838 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	24,152,223 - 24,156,509 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	24,152,479 - 24,157,337 (+)	Ensembl			panPan2	panpan1.1

RPL15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	19,825,622 - 19,829,807 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	19,825,622 - 19,829,807 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	19,823,714 - 19,827,899 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	20,138,613 - 20,142,803 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	20,138,623 - 20,142,770 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	19,947,937 - 19,952,126 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	20,057,167 - 20,061,348 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	20,166,279 - 20,170,467 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rpl15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	182,433,258 - 182,437,239 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	15,571,912 - 15,576,462 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	15,571,897 - 15,575,812 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPL15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	10,716,002 - 10,719,952 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	10,716,373 - 10,719,959 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	12,164,825 - 12,167,957 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RPL15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	68,596,897 - 68,599,575 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	68,596,968 - 68,599,389 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	41,720,551 - 41,723,247 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rpl15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	1,639,620 - 1,644,482 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624788	1,639,138 - 1,642,048 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rpl15
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	87,310,156 - 87,312,279 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rpl15
73 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	28
Count of miRNA genes:	24
Interacting mature miRNAs:	25
Transcripts:	ENSRNOT00000010759
Prediction methods:	Microtar, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	32342855	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
1300142	Bp191	Blood pressure QTL 191	3.14		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	15	1	15177511	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_139114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA687059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217514	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X78167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010759 ⟹ ENSRNOP00000010759

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	9,934,679 - 9,938,308 (+)	Ensembl
mRatBN7.2 Ensembl	15	7,503,883 - 7,507,165 (+)	Ensembl
Rnor_6.0 Ensembl	15	8,189,253 - 8,192,152 (+)	Ensembl

RefSeq Acc Id:

NM_139114 ⟹ NP_620814

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	9,934,663 - 9,937,946 (+)	NCBI
mRatBN7.2	15	7,503,883 - 7,507,166 (+)	NCBI
Rnor_6.0	15	8,188,717 - 8,192,153 (+)	NCBI
Rnor_5.0	15	12,250,776 - 12,254,212 (+)	NCBI
RGSC_v3.4	15	9,082,190 - 9,085,473 (+)	RGD
Celera	15	7,557,178 - 7,560,461 (+)	RGD

Sequence:

show sequence

GTGGGGGAGGAGCCACAAAAGGGATTGTGGGAGAAAGGCTTCTTCCTTTCCTCTAGTGGCAGCC
ATCAGGTGAGCCAAGATGGGTGCATACAAATACATCCAGGAGCTGTGGAGGAAGAAGCAGTCCG
ACGTGATGCGCTTCCTTCTAAGGGTCCGCTGCTGGCAGTACCGCCAGCTCTCTGCGCTGCACAG
GGCTCCCCGCCCCACCCGGCCTGATAAGGCGCGAAGGCTGGGATACAAGGCTAAGCAAGGTTAT
GTCATTTACAGGATCCGTGTCCGCCGCGGTGGTCGCAAGCGCCCAGTTCCTAAGGGTGCAACCT
ACGGCAAGCCTGTCCACCACGGTGTTAACCAGCTGAAGTTTGCCCGAAGCCTTCAGTCTGTTGC
TGAGGAGAGAGCTGGGCGCCATTGTGGAGCTTTGAGAGTCCTGAATTCCTACTGGGTTGGTGAA
GATTCCACATATAAATTTTTTGAGGTTATCCTCATTGATCCATTCCATAAAGCTATCAGAAGAA
ATCCCGACACCCAATGGATTACCAAACCAGTCCACAAGCACAGGGAGATGCGTGGGCTGACATC
TGCTGGCCGCAAGAGCCGTGGCCTTGGAAAGGGCCACAAGTTCCACCACACCATTGGTGGGTCT
CGCCGTGCAGCCTGGAGAAGGCGCAACACTCTTCAGCTCCACCGTTACCGCTAATTGACGTAAT
ATTTGTAAAATTCATATCCAATAAACAACTTAGGACAGTCCTCTCTGCTCACAGGTGTTATTTG
TCTGTTAGAACTAGCCTGCGGGTCGTGAGTGCTCTGTGGGGGATGGGAGCTAAAGTGCAGTAGT
AGGAAACGGCGAGTGGCGGCGCGTCTTGTTTCTGATGTACTCTGTTTGCAATTTTTGCTTAGGG
GATTAAGTGTATAGTGTTTGTGCCAAGTGGTATCCTGTGTGTAAGACTTAAAGTCCTGAAACTA
GCCTAGATGCATGAGAGAGAACCTACAGCTTTACAGTGGGGTCTCTGTTCACTGAAGTGGCTGG
CTGCTTGGAAGCTGGATGAGTACAGACAGGGAGTTGGATTTTGCTTAGAAATATGTAGGAAGAG
AGGGCTTCAAACCTGTTTTGTGACTATTCATAGAAGAGAGATCAACTATAGCTCACATTTTGAG
AATTGAATCCGTGTTCCATTTTCAGAACACTGGGTAAATTTGTTGGAAGAGGTTTCACTTCTGT
TGGATCTAGAGCATAGGTTTGACATGTGTGGATTTTGAAGCTAGTGAAGATTGAACAGTGGATA
GGGAAGGGCAGATTATTTCCATTAGGATTTATAAGCTAGTAACCATGTGGTTGCAAGTTCCTGT
CAACCAAGCAAACACAGTAAGTGGTGTCAGGCTTACAAACATTAAGCTTTAGTAGCAGCTGGTG
TGTGAAGAGGCAGGTGGATCTCCAATTCCAGGACTGCCTACAGTATAGAGAAAATGTCTCTATT
CCCGTCCATAATAGAGCAAAACCAAAAATTGGGGGCTTCCAATCAATTCGTCTTGGGTAAGGAA
CGTCCATTGGTAGTTTGATTTCATTGTTTACAGTCTGCCCGTGGGTAGATGCTCAGGTTGCTGT
CTCCTGGCATTGCCTGGACATTCTACACTCATAAAGGCCACACATGCCACTATGTTTTATTTCT
ATTTGTGCCATGCCTTGTAGTTTCCCAAAGTGATTTGAGTGGAAAAAGCAGAAATCGTCCCTAT
TACATCTGGGTTTGCTCTTTTGGACAGCAGCTAGCTTGGTATCCAAGTCTAAGTGATGCTTTTA
TTAAACCGATTTTTCCTTGGAGATTTTTAAAGGAAGATTTGATTTCCAGAAAATACTTGAGACC
TAAAATTCTCAGCAAAACAAGTCACTGTGTGTAGAGGTTGTTCAACTAGAATAATAAATGTCTG
TTAAACAAGTGGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_620814	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78724	(Get FASTA)	NCBI Sequence Viewer
	CAA55026	(Get FASTA)	NCBI Sequence Viewer
	EDL94083	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010759
	ENSRNOP00000010759.3
GenBank Protein	P61314	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_620814 ⟸ NM_139114

- UniProtKB:

P61314 (UniProtKB/Swiss-Prot), A6K036 (UniProtKB/TrEMBL), A0A8I6A471 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRI
RVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYK
FFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAW
RRRNTLQLHRYR

hide sequence

Ensembl Acc Id:

ENSRNOP00000010759 ⟸ ENSRNOT00000010759

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P61314-F1-model_v2	AlphaFold	P61314	1-204	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621181	AgrOrtholog
BioCyc Gene	G2FUF-14459	BioCyc
Ensembl Genes	ENSRNOG00000008140	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00000025212	Ensembl
Ensembl Transcript	ENSRNOT00000010759	ENTREZGENE
	ENSRNOT00000010759.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.1120.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7125608	IMAGE-MGC_LOAD
InterPro	Rbsml_L15e_core_dom_sf	UniProtKB/Swiss-Prot
	Ribosomal_L15e	UniProtKB/Swiss-Prot
	Ribosomal_L15e_CS	UniProtKB/Swiss-Prot
	Ribosomal_L23/L15e_core_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:245981	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93161	IMAGE-MGC_LOAD
NCBI Gene	245981	ENTREZGENE
PANTHER	60S RIBOSOMAL PROTEIN L15	UniProtKB/Swiss-Prot
	PTHR11847	UniProtKB/Swiss-Prot
Pfam	Ribosomal_L15e	UniProtKB/Swiss-Prot
PhenoGen	Rpl15	PhenoGen
PROSITE	RIBOSOMAL_L15E	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008140	RatGTEx
	ENSRNOG00000025212	RatGTEx
SMART	Ribosomal_L15e	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54189	UniProtKB/Swiss-Prot
UniProt	A0A8I6A471	ENTREZGENE, UniProtKB/TrEMBL
	A6K036	ENTREZGENE, UniProtKB/TrEMBL
	P61314	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	P39030	UniProtKB/Swiss-Prot
	P41051	UniProtKB/Swiss-Prot
	Q96C44	UniProtKB/Swiss-Prot
	Q9H2E5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-02-26	Rpl15	ribosomal protein L15			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Rpl15	ribosomal protein L15			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains the hexapeptide TYKFFE, that is also present in the amyloidogenic glycoprotein A4	633840
gene_other	gene may be present in 13-15 copies	633840

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - CTD

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RGD Manual Annotations