Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dync1li2 | Rat | (S)-nicotine | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Nicotine results in increased expression of DYNC1LI2 mRNA | CTD | PMID:16949557 | Dync1li2 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Dync1li2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of DYNC1LI2 mRNA | CTD | PMID:22206623 | Dync1li2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Dync1li2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:22206623 | Dync1li2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of DYNC1LI2 protein | CTD | PMID:31675489 | Dync1li2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dync1li2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DYNC1LI2 mRNA | CTD | PMID:21570461 | Dync1li2 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | 2,4,6-tribromophenol results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:31675489 | Dync1li2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of DYNC1LI2 mRNA | CTD | PMID:21346803 | Dync1li2 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of and affects the more ... | CTD | PMID:38598786 | Dync1li2 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of DYNC1LI2 mRNA | CTD | PMID:21346803 | Dync1li2 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of DYNC1LI2 protein | CTD | PMID:31675489 | Dync1li2 | Rat | 3,3',5-triiodo-L-thyronine | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Triiodothyronine results in increased expression of DYNC1LI2 mRNA | CTD | PMID:23397585 | Dync1li2 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of DYNC1LI2 protein | CTD | PMID:34915118 | Dync1li2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of DYNC1LI2 mRNA | CTD | PMID:39298647 | Dync1li2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of DYNC1LI2 mRNA | CTD | PMID:30047161 | Dync1li2 | Rat | acrolein | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Dync1li2 | Rat | aflatoxin B1 | increases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of DYNC1LI2 mRNA | CTD | PMID:19770486 | Dync1li2 | Rat | all-trans-retinoic acid | affects expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Tretinoin affects the expression of DYNC1LI2 mRNA | CTD | PMID:15498508 | Dync1li2 | Rat | alpha-pinene | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Dync1li2 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of DYNC1LI2 mRNA | CTD | PMID:30047161 | Dync1li2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DYNC1LI2 mRNA | CTD | PMID:16483693 | Dync1li2 | Rat | antirheumatic drug | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DYNC1LI2 mRNA | CTD | PMID:24449571 | Dync1li2 | Rat | aristolochic acid A | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:33212167 | Dync1li2 | Rat | arsane | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of DYNC1LI2 more ... | CTD | PMID:39836092 | Dync1li2 | Rat | arsenic atom | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of DYNC1LI2 more ... | CTD | PMID:39836092 | Dync1li2 | Rat | arsenite(3-) | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to DYNC1LI2 mRNA] | CTD | PMID:32406909 | Dync1li2 | Rat | benzo[a]pyrene | increases methylation | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of DYNC1LI2 promoter | CTD | PMID:27901495 | Dync1li2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:19150397 | Dync1li2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of DYNC1LI2 mRNA | CTD | PMID:26238291 | Dync1li2 | Rat | bisphenol A | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of DYNC1LI2 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:20678512|PMID:31675489 | Dync1li2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DYNC1LI2 mRNA | CTD | PMID:25181051 | Dync1li2 | Rat | bisphenol AF | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of DYNC1LI2 protein | CTD | PMID:34186270 | Dync1li2 | Rat | bisphenol F | increases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | bisphenol F results in increased expression of DYNC1LI2 mRNA | CTD | PMID:38685157 | Dync1li2 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of DYNC1LI2 promoter | CTD | PMID:22457795 | Dync1li2 | Rat | caffeine | affects phosphorylation | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of DYNC1LI2 protein | CTD | PMID:35688186 | Dync1li2 | Rat | CGP 52608 | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DYNC1LI2 gene] | CTD | PMID:28238834 | Dync1li2 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DYNC1LI2 mRNA | CTD | PMID:17602206 | Dync1li2 | Rat | clozapine | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Clozapine results in decreased expression of DYNC1LI2 protein | CTD | PMID:34122009 | Dync1li2 | Rat | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of DYNC1LI2 protein | CTD | PMID:25100957 | Dync1li2 | Rat | copper(II) sulfate | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of DYNC1LI2 mRNA | CTD | PMID:19549813 | Dync1li2 | Rat | crocidolite asbestos | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:29523930 | Dync1li2 | Rat | Dibutyl phosphate | affects expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of DYNC1LI2 mRNA | CTD | PMID:37042841 | Dync1li2 | Rat | disodium selenite | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:18175754 | Dync1li2 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:29391264 | Dync1li2 | Rat | enzyme inhibitor | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Dync1li2 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of DYNC1LI2 mRNA | CTD | PMID:31881178 | Dync1li2 | Rat | folic acid | multiple interactions | ISO | Dync1li2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:22206623 | Dync1li2 | Rat | FR900359 | decreases phosphorylation | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DYNC1LI2 protein | CTD | PMID:37730182 | Dync1li2 | Rat | furfural | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of DYNC1LI2 protein; [Sodium Chloride co-treated more ... | CTD | PMID:38598786 | Dync1li2 | Rat | GSK-J4 | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | GSK-J4 results in increased expression of DYNC1LI2 mRNA | CTD | PMID:29301935 | Dync1li2 | Rat | hexadecanoic acid | increases phosphorylation | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of DYNC1LI2 protein | CTD | PMID:28073184 | Dync1li2 | Rat | indometacin | increases expression | EXP | | 6480464 | Indomethacin results in increased expression of DYNC1LI2 mRNA | CTD | PMID:36868495 | Dync1li2 | Rat | ivermectin | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DYNC1LI2 protein | CTD | PMID:32959892 | Dync1li2 | Rat | menadione | affects expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of DYNC1LI2 mRNA | CTD | PMID:20044591 | Dync1li2 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:30467583 | Dync1li2 | Rat | methotrexate | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of DYNC1LI2 mRNA | CTD | PMID:24449571 | Dync1li2 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:12756304 | Dync1li2 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DYNC1LI2 mRNA | CTD | PMID:17602206 | Dync1li2 | Rat | nicotine | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Nicotine results in increased expression of DYNC1LI2 mRNA | CTD | PMID:16949557 | Dync1li2 | Rat | nitrates | multiple interactions | ISO | Dync1li2 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of DYNC1LI2 more ... | CTD | PMID:35964746 | Dync1li2 | Rat | ozone | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Dync1li2 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of DYNC1LI2 protein | CTD | PMID:26178269 | Dync1li2 | Rat | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of DYNC1LI2 mRNA | CTD | PMID:12832660 | Dync1li2 | Rat | pirinixic acid | increases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DYNC1LI2 mRNA | CTD | PMID:23811191 | Dync1li2 | Rat | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of DYNC1LI2 mRNA | CTD | PMID:30047161 | Dync1li2 | Rat | quercetin | decreases phosphorylation | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of DYNC1LI2 protein | CTD | PMID:35688186 | Dync1li2 | Rat | raloxifene | affects expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride affects the expression of DYNC1LI2 mRNA | CTD | PMID:14699072 | Dync1li2 | Rat | SB 431542 | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of DYNC1LI2 more ... | CTD | PMID:37664457 | Dync1li2 | Rat | sodium arsenite | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DYNC1LI2 mRNA | CTD | PMID:38568856 | Dync1li2 | Rat | sodium arsenite | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of DYNC1LI2 more ... | CTD | PMID:39836092 | Dync1li2 | Rat | sodium chloride | multiple interactions | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of DYNC1LI2 protein; [Sodium Chloride co-treated more ... | CTD | PMID:38598786 | Dync1li2 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of DYNC1LI2 mRNA | CTD | PMID:30047161 | Dync1li2 | Rat | tacrine | increases expression | EXP | | 6480464 | Tacrine results in increased expression of DYNC1LI2 mRNA | CTD | PMID:12832660 | Dync1li2 | Rat | tamibarotene | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | tamibarotene results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:15498508 | Dync1li2 | Rat | tetrahydropalmatine | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | tetrahydropalmatine results in decreased expression of DYNC1LI2 protein | CTD | PMID:20109541 | Dync1li2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DYNC1LI2 mRNA | CTD | PMID:23411599 | Dync1li2 | Rat | titanium dioxide | increases methylation | ISO | Dync1li2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of DYNC1LI2 gene | CTD | PMID:35295148 | Dync1li2 | Rat | triptonide | increases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | triptonide results in increased expression of DYNC1LI2 mRNA | CTD | PMID:33045310 | Dync1li2 | Rat | tungsten | decreases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:30912803 | Dync1li2 | Rat | valproic acid | decreases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DYNC1LI2 mRNA | CTD | PMID:23179753 | Dync1li2 | Rat | valproic acid | affects expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DYNC1LI2 mRNA | CTD | PMID:25979313 | Dync1li2 | Rat | zearalenone | decreases expression | ISO | Dync1li2 (Mus musculus) | 6480464 | Zearalenone results in decreased expression of DYNC1LI2 protein | CTD | PMID:36252740 | Dync1li2 | Rat | zinc sulfate | increases expression | ISO | DYNC1LI2 (Homo sapiens) | 6480464 | Zinc Sulfate results in increased expression of DYNC1LI2 mRNA | CTD | PMID:12756304 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















