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Gene: Nlgn3 (neuroligin 3) Rattus norvegicus

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Symbol:

Nlgn3

Name:

neuroligin 3

RGD ID:

621119

Description:

Enables cell adhesion molecule binding activity; neurexin family protein binding activity; and signaling receptor activity. Involved in several processes, including inhibitory postsynaptic potential; neuron cell-cell adhesion; and synapse assembly. Acts upstream of or within synapse organization. Located in several cellular components, including excitatory synapse; inhibitory synapse; and postsynaptic membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic specialization membrane. Used to study autism spectrum disorder. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN3 (neuroligin 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

gliotactin homolog; neuroligin-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NLGN3 (neuroligin 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Nlgn3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nlgn3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NLGN3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NLGN3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nlgn3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NLGN3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NLGN3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nlgn3 (neuroligin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NLGN3 (neuroligin 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nlgn3 (neuroligin 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nlgn3b (neuroligin 3b)	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	nlgn3a (neuroligin 3a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nlg-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nlg1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Nlg2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Nlg3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nlg4	Alliance	DIOPT (Hieranoid\|InParanoid\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nlgn3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Nlgn3^em1Sage

Genetic Models:

SD-Nlgn3^em1Sage

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI		GRCr8
mRatBN7.2	X	66,427,926 - 66,457,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	66,429,458 - 66,451,876 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,912,829 - 67,935,228 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	71,413,217 - 71,435,616 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,974,124 - 68,996,518 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	71,199,390 - 71,227,460 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	71,199,491 - 71,222,732 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	72,051,846 - 72,075,119 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	89,376,193 - 89,398,665 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	89,449,625 - 89,471,949 (+)	NCBI
Celera	X	66,785,377 - 66,807,774 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	autism spectrum disorder		IMP		126790492		RGD
Nlgn3	Rat	autism spectrum disorder		IMP		9831152		RGD
Nlgn3	Rat	sciatic neuropathy		IEP		9831149	mRNA:decreased expression:sciatic nerve	RGD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	autism spectrum disorder		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:25741868
Nlgn3	Rat	autistic disorder		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:12669065 more ...
Nlgn3	Rat	autosomal hemophilia A		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA A	ClinVar	PMID:31690835
Nlgn3	Rat	developmental and epileptic encephalopathy 11		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Complex neurodevelopmental disorder	ClinVar
Nlgn3	Rat	factor VIII deficiency		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Factor 8 deficiency and congenital	ClinVar	PMID:31690835
Nlgn3	Rat	FG Syndrome 1		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: FG syndrome 1	ClinVar	PMID:28492532
Nlgn3	Rat	genetic disease		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:16508939 more ...
Nlgn3	Rat	hypogonadotropic hypogonadism		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hypogonadotropic hypogonadism	ClinVar
Nlgn3	Rat	intellectual disability		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar	PMID:25167861 and PMID:25741868
Nlgn3	Rat	Klinefelter syndrome		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hypogonadotropic hypogonadism	ClinVar
Nlgn3	Rat	Neurodevelopmental Disorders		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: X-linked complex neurodevelopmental disorder	ClinVar	PMID:25741868 and PMID:31184401
Nlgn3	Rat	syndromic X-linked intellectual disability Lubs type		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs type	ClinVar	PMID:25741868
Nlgn3	Rat	X-linked severe combined immunodeficiency		ISO	NLGN3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: X-linked severe combined immunodeficiency	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	autistic disorder		ISO	NLGN3 (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:12669065 and PMID:18621663

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	autism spectrum disorder		ISS	Nlgn3 (Mus musculus)	13592920		MouseDO

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	autistic disorder	susceptibility	ISO	NLGN3 (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	1,2-dichloroethane	decreases expression	ISO	Nlgn3 (Mus musculus)	6480464	ethylene dichloride results in decreased expression of NLGN3 mRNA	CTD	PMID:28960355
Nlgn3	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Nlgn3 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of NLGN3 mRNA	CTD	PMID:22206623
Nlgn3	Rat	17alpha-ethynylestradiol	increases expression	EXP		6480464	Ethinyl Estradiol results in increased expression of NLGN3 mRNA	CTD	PMID:29097150
Nlgn3	Rat	2,2',4,4'-Tetrabromodiphenyl ether	decreases expression	EXP		6480464	2 more ...	CTD	PMID:27291303
Nlgn3	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of NLGN3 mRNA	CTD	PMID:33387578
Nlgn3	Rat	4,4'-sulfonyldiphenol	increases methylation	ISO	Nlgn3 (Mus musculus)	6480464	bisphenol S results in increased methylation of NLGN3 exon	CTD	PMID:33297965
Nlgn3	Rat	4,4'-sulfonyldiphenol	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NLGN3 mRNA	CTD	PMID:36041667
Nlgn3	Rat	5-aza-2'-deoxycytidine	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	Decitabine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 mRNA] more ...	CTD	PMID:27624276
Nlgn3	Rat	5-azacytidine	increases expression	ISO	NLGN3 (Homo sapiens)	6480464	Azacitidine results in increased expression of NLGN3 mRNA	CTD	PMID:20823114
Nlgn3	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of NLGN3 mRNA	CTD	PMID:31881176
Nlgn3	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of NLGN3 mRNA	CTD	PMID:28959563
Nlgn3	Rat	all-trans-retinoic acid	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Tretinoin results in decreased expression of NLGN3 mRNA	CTD	PMID:21934132
Nlgn3	Rat	all-trans-retinoic acid	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NLGN3 mRNA	CTD	PMID:36189433
Nlgn3	Rat	alpha-amanitin	affects expression	ISO	Nlgn3 (Mus musculus)	6480464	Alpha-Amanitin affects the expression of NLGN3 mRNA	CTD	PMID:38531469
Nlgn3	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of NLGN3 mRNA	CTD	PMID:16483693
Nlgn3	Rat	amphetamine	decreases expression	EXP		6480464	Amphetamine results in decreased expression of NLGN3 mRNA	CTD	PMID:30779732
Nlgn3	Rat	aristolochic acid A	increases expression	ISO	NLGN3 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of NLGN3 mRNA	CTD	PMID:33212167
Nlgn3	Rat	atrazine	increases expression	EXP		6480464	Atrazine results in increased expression of NLGN3 mRNA	CTD	PMID:36841081
Nlgn3	Rat	Azoxymethane	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NLGN3 mRNA	CTD	PMID:29950665
Nlgn3	Rat	belinostat	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NLGN3 mRNA	CTD	PMID:27188386
Nlgn3	Rat	belinostat	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	belinostat results in decreased expression of NLGN3 mRNA	CTD	PMID:26272509
Nlgn3	Rat	benzo[a]pyrene	increases expression	ISO	NLGN3 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased expression of NLGN3 mRNA	CTD	PMID:22316170
Nlgn3	Rat	benzo[a]pyrene	affects methylation	ISO	NLGN3 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of NLGN3 3' UTR and Benzo(a)pyrene affects the methylation of NLGN3 promoter	CTD	PMID:27901495
Nlgn3	Rat	benzo[a]pyrene	decreases methylation	ISO	NLGN3 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of NLGN3 exon	CTD	PMID:27901495
Nlgn3	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Diethylhexyl Phthalate results in decreased expression of NLGN3 mRNA	CTD	PMID:31163220
Nlgn3	Rat	bisphenol A	decreases expression	ISO	Nlgn3 (Mus musculus)	6480464	bisphenol A results in decreased expression of NLGN3 mRNA	CTD	PMID:23719926 and PMID:32156529
Nlgn3	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NLGN3 mRNA	CTD	PMID:36041667
Nlgn3	Rat	bisphenol A	decreases methylation	ISO	NLGN3 (Homo sapiens)	6480464	bisphenol A results in decreased methylation of NLGN3 gene	CTD	PMID:31601247
Nlgn3	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of NLGN3 mRNA	CTD	PMID:29097150
Nlgn3	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of NLGN3 mRNA	CTD	PMID:25181051
Nlgn3	Rat	bisphenol F	decreases expression	ISO	Nlgn3 (Mus musculus)	6480464	bisphenol F results in decreased expression of NLGN3 mRNA	CTD	PMID:30951980
Nlgn3	Rat	bisphenol F	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NLGN3 mRNA	CTD	PMID:36041667
Nlgn3	Rat	butanal	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of NLGN3 mRNA	CTD	PMID:26079696
Nlgn3	Rat	C60 fullerene	decreases expression	EXP		6480464	fullerene C60 results in decreased expression of NLGN3 mRNA	CTD	PMID:19167457
Nlgn3	Rat	cadmium atom	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NLGN3 mRNA	CTD	PMID:35301059
Nlgn3	Rat	cadmium dichloride	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NLGN3 mRNA	CTD	PMID:35301059
Nlgn3	Rat	CGP 52608	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to NLGN3 gene]	CTD	PMID:28238834
Nlgn3	Rat	cisplatin	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[Cisplatin co-treated with jinfukang] results in decreased expression of NLGN3 mRNA	CTD	PMID:27392435
Nlgn3	Rat	decabromodiphenyl ether	increases expression	EXP		6480464	decabromobiphenyl ether results in increased expression of NLGN3 mRNA	CTD	PMID:23914054
Nlgn3	Rat	dextran sulfate	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NLGN3 mRNA	CTD	PMID:29950665
Nlgn3	Rat	Dibutyl phosphate	affects expression	ISO	NLGN3 (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of NLGN3 mRNA	CTD	PMID:37042841
Nlgn3	Rat	dibutyl phthalate	increases expression	ISO	Nlgn3 (Mus musculus)	6480464	Dibutyl Phthalate results in increased expression of NLGN3 mRNA	CTD	PMID:21266533
Nlgn3	Rat	dioxygen	increases expression	ISO	Nlgn3 (Mus musculus)	6480464	Oxygen deficiency results in increased expression of NLGN3 mRNA	CTD	PMID:16373842
Nlgn3	Rat	dioxygen	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of NLGN3 mRNA]	CTD	PMID:16373842
Nlgn3	Rat	dorsomorphin	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
Nlgn3	Rat	ethanol	affects splicing	ISO	Nlgn3 (Mus musculus)	6480464	Ethanol affects the splicing of NLGN3 mRNA	CTD	PMID:30319688
Nlgn3	Rat	ethylparaben	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	ethyl-p-hydroxybenzoate results in decreased expression of NLGN3 mRNA	CTD	PMID:37690743
Nlgn3	Rat	flavonoids	decreases expression	EXP		6480464	Flavonoids results in decreased expression of NLGN3 mRNA	CTD	PMID:18035473
Nlgn3	Rat	folic acid	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Folic Acid results in decreased expression of NLGN3 mRNA	CTD	PMID:21867686
Nlgn3	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of NLGN3 mRNA	CTD	PMID:33387578
Nlgn3	Rat	glutathione	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	Glutathione inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA] more ...	CTD	PMID:27624276
Nlgn3	Rat	hydrogen peroxide	increases methylation	ISO	NLGN3 (Homo sapiens)	6480464	Hydrogen Peroxide results in increased methylation of NLGN3 promoter	CTD	PMID:27624276
Nlgn3	Rat	hydrogen peroxide	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA] more ...	CTD	PMID:27624276
Nlgn3	Rat	hydrogen peroxide	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Hydrogen Peroxide results in decreased expression of NLGN3 mRNA	CTD	PMID:27624276
Nlgn3	Rat	lead(0)	affects splicing	ISO	NLGN3 (Homo sapiens)	6480464	Lead affects the splicing of NLGN3 mRNA	CTD	PMID:28903495
Nlgn3	Rat	lead(0)	affects expression	ISO	NLGN3 (Homo sapiens)	6480464	Lead affects the expression of NLGN3 mRNA	CTD	PMID:28903495
Nlgn3	Rat	mono(2-ethylhexyl) phthalate	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NLGN3 mRNA	CTD	PMID:36189433
Nlgn3	Rat	N-acetyl-L-cysteine	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA] more ...	CTD	PMID:27624276
Nlgn3	Rat	N-ethyl-N-nitrosourea	increases mutagenesis	EXP		6480464	Ethylnitrosourea results in increased mutagenesis of NLGN3 gene	CTD	PMID:16495775
Nlgn3	Rat	ozone	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[Air Pollutants results in increased abundance of Ozone] which affects the expression of NLGN3 mRNA	CTD	PMID:35430440
Nlgn3	Rat	phenylmercury acetate	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Phenylmercuric Acetate results in decreased expression of NLGN3 mRNA	CTD	PMID:26272509
Nlgn3	Rat	phenylmercury acetate	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NLGN3 mRNA	CTD	PMID:27188386
Nlgn3	Rat	poly(I:C)	multiple interactions	EXP		6480464	[Poly I-C co-treated with HU 211] results in decreased expression of NLGN3 mRNA	CTD	PMID:26923065
Nlgn3	Rat	S-adenosyl-L-methioninate	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA] more ...	CTD	PMID:27624276
Nlgn3	Rat	S-adenosyl-L-methionine	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA] more ...	CTD	PMID:27624276
Nlgn3	Rat	SB 431542	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
Nlgn3	Rat	simvastatin	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of NLGN3 mRNA]	CTD	PMID:16373842
Nlgn3	Rat	sodium arsenite	increases expression	ISO	NLGN3 (Homo sapiens)	6480464	sodium arsenite results in increased expression of NLGN3 mRNA	CTD	PMID:38568856
Nlgn3	Rat	sunitinib	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Sunitinib results in decreased expression of NLGN3 mRNA	CTD	PMID:31533062
Nlgn3	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of NLGN3 mRNA	CTD	PMID:34492290
Nlgn3	Rat	titanium dioxide	multiple interactions	ISO	Nlgn3 (Mus musculus)	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NLGN3 mRNA	CTD	PMID:29950665
Nlgn3	Rat	titanium dioxide	increases expression	ISO	Nlgn3 (Mus musculus)	6480464	titanium dioxide results in increased expression of NLGN3 mRNA	CTD	PMID:35295148
Nlgn3	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of NLGN3 mRNA	CTD	PMID:33387578
Nlgn3	Rat	trichostatin A	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	trichostatin A results in decreased expression of NLGN3 mRNA	CTD	PMID:26272509
Nlgn3	Rat	trichostatin A	multiple interactions	ISO	NLGN3 (Homo sapiens)	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NLGN3 mRNA	CTD	PMID:27188386
Nlgn3	Rat	triphenyl phosphate	affects expression	ISO	NLGN3 (Homo sapiens)	6480464	triphenyl phosphate affects the expression of NLGN3 mRNA	CTD	PMID:37042841
Nlgn3	Rat	triptonide	increases expression	ISO	Nlgn3 (Mus musculus)	6480464	triptonide results in increased expression of NLGN3 mRNA	CTD	PMID:33045310
Nlgn3	Rat	valproic acid	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	Valproic Acid results in decreased expression of NLGN3 mRNA	CTD	PMID:23179753 and PMID:28001369
Nlgn3	Rat	valproic acid	decreases expression	EXP		6480464	Valproic Acid results in decreased expression of NLGN3 mRNA	CTD	PMID:30404997
Nlgn3	Rat	valproic acid	affects splicing	EXP		6480464	Valproic Acid affects the splicing of NLGN3 mRNA	CTD	PMID:29427782
Nlgn3	Rat	vorinostat	decreases expression	ISO	NLGN3 (Homo sapiens)	6480464	vorinostat results in decreased expression of NLGN3 mRNA	CTD	PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	adult behavior	involved_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:12669065	RGD	PMID:12669065
Nlgn3	Rat	adult behavior	involved_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	axon extension	involved_in	IMP		8554851	PMID:19406211	BHF-UCL
Nlgn3	Rat	cell adhesion	involved_in	IEA	UniProtKB-KW:KW-0130	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Nlgn3	Rat	chemical synaptic transmission	involved_in	IBA	FB:FBgn0031866 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	circadian sleep/wake cycle		IMP		126790492		RGD
Nlgn3	Rat	excitatory postsynaptic potential	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	excitatory postsynaptic potential	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	inhibitory postsynaptic potential	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	inhibitory postsynaptic potential	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	MGI:3758949 PMID:17823315	RGD	PMID:17823315
Nlgn3	Rat	inhibitory postsynaptic potential	involved_in	IDA		8554851	PMID:19406211	BHF-UCL
Nlgn3	Rat	learning	involved_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:12669065	RGD	PMID:12669065
Nlgn3	Rat	learning	involved_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	long-term synaptic potentiation	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	membrane assembly	involved_in	IEA	ARBA:ARBA00028930	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Nlgn3	Rat	modulation of chemical synaptic transmission	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	modulation of chemical synaptic transmission	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	MGI:2179435 more ...	RGD	PMID:16982420
Nlgn3	Rat	modulation of chemical synaptic transmission	involved_in	IBA	FB:FBgn0031866 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	negative regulation of dendritic spine morphogenesis	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	negative regulation of excitatory postsynaptic potential	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	neuron cell-cell adhesion	involved_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	neuron cell-cell adhesion	involved_in	IBA	PANTHER:PTN000168538 and Nlgn3 (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	oligodendrocyte differentiation	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	PMID:19139271	RGD	PMID:19139271
Nlgn3	Rat	positive regulation of AMPA receptor activity	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21642956	RGD	PMID:21642956
Nlgn3	Rat	positive regulation of dendritic spine development		IMP		8553420		RGD
Nlgn3	Rat	positive regulation of excitatory postsynaptic potential	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21642956	RGD	PMID:21642956
Nlgn3	Rat	positive regulation of excitatory postsynaptic potential	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	positive regulation of glutamate receptor signaling pathway	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	positive regulation of glutamate receptor signaling pathway	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21642956	RGD	PMID:21642956
Nlgn3	Rat	positive regulation of inhibitory postsynaptic potential		IDA		8554851		RGD
Nlgn3	Rat	positive regulation of multicellular organismal process	involved_in	IEA	ARBA:ARBA00028891	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Nlgn3	Rat	positive regulation of protein localization to synapse		IMP		8553420		RGD
Nlgn3	Rat	positive regulation of synapse assembly	involved_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	positive regulation of synapse assembly	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21642956	RGD	PMID:21642956
Nlgn3	Rat	positive regulation of synaptic transmission, glutamatergic	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	positive regulation of synaptic transmission, glutamatergic	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21642956	RGD	PMID:21642956
Nlgn3	Rat	positive regulation of synaptic vesicle clustering	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	postsynaptic membrane assembly	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	postsynaptic membrane assembly	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21642956	RGD	PMID:21642956
Nlgn3	Rat	postsynaptic membrane assembly	involved_in	IBA	MGI:2444609 and PANTHER:PTN000168538	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	postsynaptic specialization assembly	involved_in	IDA		9831151	PMID:17897391	SynGO
Nlgn3	Rat	prepulse inhibition		IMP		126790492		RGD
Nlgn3	Rat	presynaptic membrane assembly	involved_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	presynaptic membrane assembly	involved_in	IBA	FB:FBgn0051146 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	receptor-mediated endocytosis	involved_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	regulation of AMPA receptor activity	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	regulation of dendritic spine morphogenesis	involved_in	ISS	UniProtKB:Q8BYM5	8553412	PMID:21808020	BHF-UCL
Nlgn3	Rat	regulation of dendritic spine morphogenesis	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	regulation of dendritic spine morphogenesis	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	regulation of long-term synaptic potentiation	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	regulation of long-term synaptic potentiation	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	regulation of long-term synaptic potentiation	involved_in	ISS	UniProtKB:Q8BYM5	8553412	PMID:21808020	BHF-UCL
Nlgn3	Rat	regulation of membrane potential	involved_in	IEA	ARBA:ARBA00028934	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Nlgn3	Rat	regulation of nervous system process	involved_in	IEA	ARBA:ARBA00028761	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Nlgn3	Rat	regulation of NMDA receptor activity	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	regulation of respiratory gaseous exchange by nervous system process	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	regulation of respiratory gaseous exchange by nervous system process	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	MGI:2179435 more ...	RGD	PMID:16982420
Nlgn3	Rat	regulation of signal transduction	involved_in	IEA	ARBA:ARBA00027204	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Nlgn3	Rat	regulation of synaptic transmission, glutamatergic	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	regulation of synaptic transmission, glutamatergic	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	regulation of terminal button organization	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	regulation of terminal button organization	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	regulation of terminal button organization	involved_in	ISS	UniProtKB:Q8BYM5	8553412	PMID:21808020	BHF-UCL
Nlgn3	Rat	rhythmic synaptic transmission	involved_in	IMP		8554851	PMID:19406211	BHF-UCL
Nlgn3	Rat	social behavior	involved_in	ISS	UniProtKB:Q8BYM5	1600115	GO_REF:0000024	BHF-UCL	GO_REF:0000024
Nlgn3	Rat	social behavior	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	MGI:3758949 PMID:17823315	RGD	PMID:17823315
Nlgn3	Rat	social behavior	involved_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:12669065	RGD	PMID:12669065
Nlgn3	Rat	social behavior	involved_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	social behavior	involved_in	ISO	Nlgn3 (Mus musculus)	1624291	PMID:21808020	RGD	PMID:21808020
Nlgn3	Rat	synapse assembly	involved_in	IEA	ARBA:ARBA00026559	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Nlgn3	Rat	synapse assembly	involved_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	synapse organization	acts_upstream_of_or_within	IDA		8553420	PMID:15681343	MGI
Nlgn3	Rat	synapse organization	involved_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	synapse organization	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	MGI:2179435 more ...	RGD	PMID:21788371
Nlgn3	Rat	synapse organization	involved_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:15150161	RGD	PMID:15150161
Nlgn3	Rat	synaptic vesicle endocytosis	involved_in	IBA	FB:FBgn0083963 and PANTHER:PTN000168538	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	visual learning	acts_upstream_of_or_within	ISO	Nlgn3 (Mus musculus)	1624291	MGI:3758949 PMID:17823315	RGD	PMID:17823315
Nlgn3	Rat	vocalization behavior	involved_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	vocalization behavior	involved_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:12669065	RGD	PMID:12669065

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	cell surface	located_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	cell surface	is_active_in	IBA	PANTHER:PTN000168538 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	cell surface	located_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:15150161 and PMID:17292328	RGD	PMID:15150161 and PMID:17292328
Nlgn3	Rat	cell surface	located_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	dendrite	located_in	IDA		9831151		RGD
Nlgn3	Rat	endocytic vesicle	located_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	excitatory synapse	located_in	IDA		9831151		RGD
Nlgn3	Rat	excitatory synapse	located_in	ISO	NLGN3 (Homo sapiens)	1624291	PMID:15620359	RGD	PMID:15620359
Nlgn3	Rat	excitatory synapse	located_in	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	excitatory synapse	located_in	IDA		8554031	PMID:19914352	BHF-UCL
Nlgn3	Rat	GABA-ergic synapse	is_active_in	IDA		9831151	PMID:17897391	SynGO
Nlgn3	Rat	GABA-ergic synapse	is_active_in	IEP		9831151	PMID:17897391	SynGO
Nlgn3	Rat	glutamatergic synapse	is_active_in	IDA		9831151	PMID:17897391	SynGO
Nlgn3	Rat	glutamatergic synapse	is_active_in	IEP		9831151	PMID:17897391	SynGO
Nlgn3	Rat	inhibitory synapse		IDA		8554031		RGD
Nlgn3	Rat	inhibitory synapse	located_in	IC	GO:0060080	8554851	PMID:19406211	BHF-UCL
Nlgn3	Rat	inhibitory synapse	located_in	IDA		9831151		RGD
Nlgn3	Rat	membrane	located_in	IEA	InterPro:IPR000460	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nlgn3	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Nlgn3	Rat	neuronal cell body		IDA		9831151		RGD
Nlgn3	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Nlgn3	Rat	plasma membrane	is_active_in	IBA	FB:FBgn0031866 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Nlgn3	Rat	postsynaptic membrane	located_in	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	postsynaptic specialization membrane	is_active_in	IDA		9831151	PMID:17897391	SynGO
Nlgn3	Rat	postsynaptic specialization membrane	is_active_in	IEP		9831151	PMID:17897391	SynGO
Nlgn3	Rat	presynapse	located_in	IEA	GO:0048488	1600115	GO_REF:0000108	GOC	GO_REF:0000108
Nlgn3	Rat	synapse	located_in	IEA	UniProtKB-SubCell:SL-0258	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Nlgn3	Rat	synapse	is_active_in	IBA	FB:FBgn0031866 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	synapse	located_in	IDA		8553420	PMID:15681343	MGI
Nlgn3	Rat	synapse	located_in	IEA	UniProtKB-KW:KW-0770	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	cell adhesion molecule binding	enables	IPI	UniProtKB:Q63373	8553271	PMID:15152050	BHF-UCL
Nlgn3	Rat	neurexin family protein binding	enables	IPI	UniProtKB:Q63373	8553271	PMID:15152050	BHF-UCL
Nlgn3	Rat	neurexin family protein binding	enables	IBA	FB:FBgn0031866 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nlgn3	Rat	neurexin family protein binding	enables	IEA	InterPro:IPR000460	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nlgn3	Rat	protein binding	enables	ISO	NLGN3 (Homo sapiens) and UniProtKB:Q9NZ94-2	1624291	UniProtKB:P00403 more ...	RGD	PMID:25464930
Nlgn3	Rat	protein binding	enables	ISO	NLGN3 (Homo sapiens)	1624291	UniProtKB:Q9NY99 more ...	RGD	PMID:17292328 and PMID:26871637
Nlgn3	Rat	scaffold protein binding	enables	ISO	NLGN3 (Homo sapiens)	1624291	UniProtKB:Q9NY99 and PMID:17292328	RGD	PMID:17292328
Nlgn3	Rat	scaffold protein binding	enables	IEA	UniProtKB:Q9NZ94 and ensembl:ENSP00000351591	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nlgn3	Rat	signaling receptor activity	enables	IDA		8554205	PMID:15797875	BHF-UCL
Nlgn3	Rat	signaling receptor activity	enables	IBA	PANTHER:PTN000168538 and Nlgn3 (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nlgn3	Rat	abnormal brain wave pattern		IMP		126790492		RGD
Nlgn3	Rat	abnormal non-rapid eye movement sleep pattern		IMP		126790492	during light cycle	RGD
Nlgn3	Rat	abnormal paradoxical sleep pattern		IMP		126790492	during light cycle	RGD
Nlgn3	Rat	abnormal social investigation		IMP		126790492		RGD
Nlgn3	Rat	abnormal social play behavior		IMP		126790492		RGD
Nlgn3	Rat	abnormal social play behavior		IMP		9831152		RGD
Nlgn3	Rat	decreased anxiety-related response		IMP		9831152		RGD
Nlgn3	Rat	decreased body weight		IMP		126790492		RGD
Nlgn3	Rat	decreased body weight		IMP		9831152		RGD
Nlgn3	Rat	decreased prepulse inhibition		IMP		126790492		RGD
Nlgn3	Rat	decreased prepulse inhibition		IMP		9831152		RGD
Nlgn3	Rat	hyperactivity		IMP		126790492		RGD
Nlgn3	Rat	increased anxiety-related response		IMP		126790492		RGD
Nlgn3	Rat	increased gnawing activity		IMP		126790492		RGD
Nlgn3	Rat	increased gnawing activity		IMP		9831152		RGD
Nlgn3	Rat	increased grooming behavior		IMP		9831152		RGD
Nlgn3	Rat	increased vertical activity		IMP		9831152		RGD

#	Reference Title	Reference Citation
1.	Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.	Budreck EC and Scheiffele P, Eur J Neurosci. 2007 Oct;26(7):1738-48.
2.	Control of excitatory and inhibitory synapse formation by neuroligins.	Chih B, etal., Science. 2005 Feb 25;307(5713):1324-8. Epub 2005 Jan 27.
3.	Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism.	Chubykin AA, etal., J Biol Chem. 2005 Jun 10;280(23):22365-74. Epub 2005 Mar 29.
4.	The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing.	Comoletti D, etal., J Neurosci. 2004 May 19;24(20):4889-93.
5.	Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function.	Etherton M, etal., Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13764-9. doi: 10.1073/pnas.1111093108. Epub 2011 Aug 1.
6.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
8.	Altered synchrony and connectivity in neuronal networks expressing an autism-related mutation of neuroligin 3.	Gutierrez RC, etal., Neuroscience. 2009 Aug 4;162(1):208-21. doi: 10.1016/j.neuroscience.2009.04.062. Epub 2009 May 3.
9.	Fmr1 and Nlgn3 knockout rats: novel tools for investigating autism spectrum disorders.	Hamilton SM, etal., Behav Neurosci. 2014 Apr;128(2):103-9. doi: 10.1037/a0035988.
10.	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	Ichtchenko K, etal., J Biol Chem 1996 Feb 2;271(5):2676-82.
11.	Postsynaptic scaffolding molecules modulate the localization of neuroligins.	Levinson JN, etal., Neuroscience. 2010 Feb 3;165(3):782-93. doi: 10.1016/j.neuroscience.2009.11.016. Epub 2009 Nov 13.
12.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
13.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
14.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic beta cell function.	Suckow AT, etal., J Biol Chem. 2012 Jun 8;287(24):19816-26. doi: 10.1074/jbc.M111.280537. Epub 2012 Apr 23.
18.	Sleep/Wake Physiology and Quantitative Electroencephalogram Analysis of the Neuroligin-3 Knockout Rat Model of Autism Spectrum Disorder.	Thomas AM, etal., Sleep. 2017 Oct 1;40(10). pii: 4100612. doi: 10.1093/sleep/zsx138.
19.	Down-regulation of mRNAs for synaptic adhesion molecules neuroligin-2 and -3 and synCAM1 in spinal motoneurons after axotomy.	Zelano J, etal., J Comp Neurol. 2007 Jul 10;503(2):308-18.

PMID:11329178	PMID:12669065	PMID:15150161	PMID:15620359	PMID:16982420	PMID:17292328	PMID:17823315	PMID:18755801	PMID:19139271	PMID:19816407	PMID:20615874	PMID:21532576
PMID:21642956	PMID:21788371	PMID:22671294	PMID:25565602	PMID:26621873	PMID:27805570	PMID:30790215

Nlgn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI		GRCr8
mRatBN7.2	X	66,427,926 - 66,457,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	66,429,458 - 66,451,876 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,912,829 - 67,935,228 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	71,413,217 - 71,435,616 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,974,124 - 68,996,518 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	71,199,390 - 71,227,460 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	71,199,491 - 71,222,732 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	72,051,846 - 72,075,119 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	89,376,193 - 89,398,665 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	89,449,625 - 89,471,949 (+)	NCBI
Celera	X	66,785,377 - 66,807,774 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

NLGN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	71,144,841 - 71,175,307 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	71,144,821 - 71,175,255 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	70,364,691 - 70,391,051 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	70,281,436 - 70,307,776 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	70,147,731 - 70,174,070	NCBI
Celera	X	70,718,556 - 70,744,930 (+)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	64,183,444 - 64,209,758 (+)	NCBI		HuRef
CHM1_1	X	70,257,401 - 70,284,066 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	69,578,926 - 69,609,395 (+)	NCBI		T2T-CHM13v2.0

Nlgn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	100,342,785 - 100,364,956 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	100,342,774 - 100,369,569 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	101,299,179 - 101,321,350 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	101,299,168 - 101,325,963 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	98,494,520 - 98,516,689 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	97,501,929 - 97,524,067 (+)	NCBI		MGSCv36	mm8
Celera	X	88,215,228 - 88,237,795 (+)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	43.95	NCBI

Nlgn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955475	10,712,170 - 10,735,857 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955475	10,712,170 - 10,735,857 (+)	NCBI	ChiLan1.0	ChiLan1.0

NLGN3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	70,822,214 - 70,848,479 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	70,825,828 - 70,852,082 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	60,413,098 - 60,439,359 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	70,469,764 - 70,496,526 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	70,469,764 - 70,496,526 (+)	Ensembl	panpan1.1		panPan2

NLGN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	55,510,729 - 55,532,396 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	55,513,626 - 55,531,371 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	46,337,800 - 46,359,510 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	56,479,897 - 56,501,589 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	56,479,918 - 56,501,589 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	54,447,828 - 54,469,515 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	55,779,249 - 55,800,946 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	55,706,411 - 55,728,100 (+)	NCBI		UU_Cfam_GSD_1.0

Nlgn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	46,672,077 - 46,696,110 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936762	435,729 - 458,423 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936762	435,729 - 458,261 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NLGN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	57,176,103 - 57,201,461 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	57,174,506 - 57,204,770 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	64,705,492 - 64,727,915 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NLGN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	60,941,371 - 60,967,942 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	60,941,654 - 60,967,936 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	2,802,397 - 2,828,656 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nlgn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624903	1,438,428 - 1,463,172 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624903	1,437,663 - 1,465,955 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Nlgn3
26 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	422
Count of miRNA genes:	106
Interacting mature miRNAs:	122
Transcripts:	ENSRNOT00000005077, ENSRNOT00000005102, ENSRNOT00000042648, ENSRNOT00000050672
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat

RH79662

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	66,427,531 - 66,427,714 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	71,197,572 - 71,197,754	NCBI	Rnor6.0
Rnor_5.0	X	72,050,050 - 72,050,232	UniSTS	Rnor5.0
RGSC_v3.4	X	89,374,249 - 89,374,431	UniSTS	RGSC3.4
Celera	X	66,783,433 - 66,783,615	UniSTS
Cytogenetic Map	X	q31	UniSTS

MARC_10371-10372:999098922:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	66,449,655 - 66,449,979 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	71,219,732 - 71,220,055	NCBI	Rnor6.0
Rnor_5.0	X	72,071,783 - 72,072,106	UniSTS	Rnor5.0
RGSC_v3.4	X	89,396,446 - 89,396,769	UniSTS	RGSC3.4
Celera	X	66,805,555 - 66,805,878	UniSTS
Cytogenetic Map	X	q31	UniSTS

This gene Nlgn3 is modified in the following models/strains:

SD-Nlgn3^em1Sage

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001431657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_134336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_197237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_197238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_197239	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010061164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010061165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010061166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010061167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010061168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010061169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CB771914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U41663	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005077 ⟹ ENSRNOP00000005077

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	66,429,476 - 66,451,876 (+)	Ensembl
Rnor_6.0 Ensembl	X	71,199,516 - 71,222,006 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000005102 ⟹ ENSRNOP00000005102

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	66,429,458 - 66,451,876 (+)	Ensembl
Rnor_6.0 Ensembl	X	71,199,532 - 71,222,732 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076168 ⟹ ENSRNOP00000068393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	66,429,458 - 66,451,876 (+)	Ensembl
Rnor_6.0 Ensembl	X	71,199,491 - 71,220,041 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108642 ⟹ ENSRNOP00000080050

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	66,429,476 - 66,451,876 (+)	Ensembl

RefSeq Acc Id:

NM_134336 ⟹ NP_599163

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,478 - 70,491,878 (+)	NCBI
mRatBN7.2	X	66,429,476 - 66,451,876 (+)	NCBI
Rnor_6.0	X	71,199,516 - 71,221,951 (+)	NCBI
Rnor_5.0	X	72,051,846 - 72,075,119 (+)	NCBI
RGSC_v3.4	X	89,376,193 - 89,398,665 (+)	RGD
Celera	X	66,785,377 - 66,807,774 (+)	RGD

Sequence:

show sequence

CCGGAGAGCTGATCTCGGGATTCGGGTGCGGACGCCTTGGCCTGGAGGCGATATGGGTGGTCCGTGGCCCGGTTCAGTCGTTTGCAGCCGCCTAGGGAACAGGCCTGTCTGGCCCTAAGGGAGCCCTC
TTTCGAAGTGGTGGTGCTCGGACGACCTGCTCTCTGCGTGGCTGGGCACCTGTAGGTGTCCCTCGAGAGCTCAGTTTTGAGGTTCAAGCCAGTGTGGCCATGAAGTGGCTGCCTATTGGGCTGATGCT
GTGACCCCGGAGTCTTCCTCTCCTGCCAGTCCCCCTGCCCGGAACATGTGGCTGCAGCTCGGCCTGCCCTCGTTGTCCCTGAGCCCCACGCCCACAGTTGGCCGGAGCCTGTGCCTCATCCTGTGGTT
CCTCAGTTTGGTGCTGAGGGCCAGTACCCAGGCCCCGGCACCCACAGTCAATACTCACTTTGGGAAACTAAGGGGTGCCAGAGTACCATTGCCCAGTGAAATCCTGGGTCCTGTGGACCAATACCTGG
GGGTACCCTACGCAGCTCCCCCGATCGGCGAGAAACGTTTCCTGCCCCCTGAACCACCCCCATCCTGGTCGGGCATCCGGAACGCCACACACTTTCCCCCAGTGTGCCCCCAGAACATCCACACAGCT
GTGCCCGAAGTCATGCTGCCAGTCTGGTTCACTGCCAACTTGGATATCGTCGCCACTTATATCCAGGAGCCCAACGAAGATTGCCTCTATCTGAATGTGTATGTGCCCACGGAAGATGTAAAGCGGAT
TTCCAAGGAATGCGCCCGAAAGCCCAACAAGAAAATTTGTAGGAAAGGAGGATCCGGCGCTAAGAAACAGGGCGAGGACTTAGCGGATAATGACGGGGATGAAGATGAAGACATCCGAGACAGTGGTG
CTAAACCTGTCATGGTCTACATCCACGGAGGCTCTTACATGGAAGGAACAGGCAACATGATTGACGGCAGCGTTCTTGCAAGTTATGGCAACGTCATCGTCATCACACTCAACTACCGGGTCGGGGTG
CTAGGTTTCCTGAGCACTGGGGATCAGGCTGCCAAGGGCAACTATGGGCTCCTTGATCAAATCCAGGCCCTTCGCTGGGTGAGTGAGAACATTGCCTTCTTTGGAGGAGATCCCCGTAGAATTACTGT
CTTTGGCTCTGGCATTGGTGCATCCTGTGTCAGTCTTCTCACACTGTCTCATCACTCTGAGGGGCTTTTCCAGAGGGCCATCATCCAAAGTGGCTCAGCGCTATCTAGCTGGGCTGTGAACTACCAAC
CAGTGAAGTACACCAGCTTGCTCGCAGACAAAGTGGGCTGTAACGTCCTGGACACTGTGGATATGGTGGATTGTCTTCGACAAAAGAGTGCCAAGGAGCTGGTAGAACAGGACATTCAGCCAGCCCGC
TACCATGTGGCTTTTGGCCCTGTGATTGATGGTGATGTCATTCCTGATGACCCTGAGATCCTTATGGAACAGGGAGAGTTCCTCAACTATGATATCATGCTAGGCGTCAACCAGGGTGAGGGTCTCAA
GTTTGTGGAAGGGGTGGTGGACCCCGAGGATGGTGTCTCTGGCACTGACTTTGACTACTCTGTCTCCAATTTTGTGGACAATCTATATGGCTATCCCGAGGGTAAGGACACCCTGCGGGAGACTATCA
AGTTCATGTATACAGACTGGGCAGACCGAGACAACCCTGAGACCCGCCGTAAAACACTGGTGGCACTCTTCACTGACCACCAGTGGGTGGAGCCTTCGGTGGTGACAGCTGATCTGCATGCCCGCTAT
GGCTCACCCACTTACTTCTACGCCTTCTACCATCACTGCCAGAGCCTCATGAAGCCTGCATGGTCAGATGCAGCACACGGGGATGAAGTACCCTATGTTTTTGGTGTCCCTATGGTAGGTCCCACTGA
CCTTTTCCCCTGCAACTTCTCCAAGAATGATGTTATGCTCAGTGCTGTTGTTATGACCTATTGGACCAACTTTGCCAAGACCGGGGATCCCAACAAGCCGGTACCCCAGGATACCAAGTTCATTCACA
CCAAGGCCAACCGCTTTGAGGAAGTAGCCTGGTCCAAATACAATCCCCGGGACCAGCTCTACCTTCACATCGGGCTGAAACCAAGGGTTCGTGATCATTACCGAGCCACAAAGGTAGCCTTTTGGAAG
CACCTGGTACCCCATCTGTACAACCTGCATGACATGTTCCACTATACATCCACGACCACGAAAGTGCCGCCGCCGGACACCACCCATAGCTCCCACATCACCCGTAGGCCCAACGGCAAGACCTGGAG
CACCAAGAGGCCAGCCATCTCACCTGCCTACAGCAATGAGAATGCTCCTGGGTCCTGGAATGGGGACCAGGATGCAGGGCCACTCCTGGTCGAGAACCCTCGAGACTACTCCACTGAATTAAGTGTCA
CCATCGCTGTTGGGGCCTCTCTCCTGTTTCTCAATGTGTTGGCCTTTGCTGCTCTCTATTACCGTAAGGACAAACGGCGCCAGGAGCCCCTGAGGCAGCCTAGCCCCCAAAGGGGAACTGGTGCCCCA
GAATTGGGAACTGCTCCAGAGGAGGAGCTGGCAGCATTACAGTTGGGTCCCACTCACCATGAGTGTGAGGCCGGCCCCCCACACGACACACTGCGCCTCACAGCATTGCCCGACTACACCCTGACCCT
GCGGCGCTCCCCCGATGACATCCCACTCATGACTCCCAACACCATCACTATGATTCCCAATTCCCTGGTTGGGTTGCAGACCTTGCACCCCTATAACACCTTTGCCGCCGGATTCAACAGCACCGGGC
TGCCCCACTCACACTCCACTACCCGTGTATAGCTCTATCCCAGAGCACAACCCATCTCCCAGATCCCTCCCTCCCAGATCCACAAACACACATGCACACACATACACATATATGTACACGCACGCACC
CACACCCTACAGCAGACCCATCTGCACAAACACAGACAGATGTGGACATGCACCCGCATGTACAAAAAAACACAAATCCAGAAGAGAACCTGAATAGGCCCTTCAAATGGGGACACATATGAGTCCTT
GGAACCAAGGGCCCATGAAATAGCAGCTGGAGCCAGCTCCTTGAGCCCGACCACAGACACTCCTGGGGCCCTGGAAGCCACAGCCGGACACCCC

hide sequence

RefSeq Acc Id:

XM_006257054 ⟹ XP_006257116

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,495,548 (+)	NCBI
mRatBN7.2	X	66,427,926 - 66,452,659 (+)	NCBI
Rnor_6.0	X	71,199,390 - 71,222,734 (+)	NCBI
Rnor_5.0	X	72,051,846 - 72,075,119 (+)	NCBI

Sequence:

show sequence

ATTGGGCCATGCCCCAGGACTTGAGCCATCACTGGCACAAAAGGAGTTAATGCCAGGGACCGCGCCCCCCCGTGTCCGGGCACGCGCAGCGCGCCCCCTTGGTGCGCGGGCACAGCAGCCAGGCTGCC
GGAGAGCTGATCTCGGGATTCGGGTGCGGAGCCCTTGGCCTGGAGGCGATATGGGTGGTCCGTGGCCCGGTTCAGTCGTTTGCAGCCGCCTAGGGAACAGGCCTGTCTGGCCCTAAGGGAGCCCTCTT
TCGAAGTGGTGGTGCTCGGACGACCTGCTCTCTGCGTGGCTGGGCACCTGTAGGTGTCCCTCGAGAGCTCAGTTTTGAGGTTCAAGCCAGTGTGGCCATGAAGTGGCTGCCTATTGGGCTGATGCTGT
GACCCCGGAGTCTTCCTCTCCTGCCAGTCCCCCTGCCCGGAACATGTGGCTGCAGCTCGGCCTGCCCTCGTTGTCCCTGAGCCCCACGCCCACAGTTGGCCGGAGCCTGTGCCTCATCCTGTGGTTCC
TCAGTTTGGTGCTGAGGGCCAGTACCCAGGCCCCGGCACCCACAGTCAATACTCACTTTGGGAAACTAAGGGGTGCCAGAGTACCATTGCCCAGTGAAATCCTGGGTCCTGTGGACCAATACCTGGGG
GTACCCTACGCAGCTCCCCCGATCGGCGAGAAACGTTTCCTGCCCCCTGAACCACCCCCATCCTGGTCGGGCATCCGGAACGCCACACACTTTCCCCCAGTGTGCCCCCAGAACATCCACACAGCTGT
GCCCGAAGTCATGCTGCCAGTCTGGTTCACTGCCAACTTGGATATCGTCGCCACTTATATCCAGGAGCCCAACGAAGATTGCCTCTATCTGAATGTGTATGTGCCCACGGAAGATGGATCCGGCGCTA
AGAAACAGGGCGAGGACTTAGCGGATAATGACGGGGATGAAGATGAAGACATCCGAGACAGTGGTGCTAAACCTGTCATGGTCTACATCCACGGAGGCTCTTACATGGAAGGAACAGGCAACATGATT
GACGGCAGCGTTCTTGCAAGTTATGGCAACGTCATCGTCATCACACTCAACTACCGGGTCGGGGTGCTAGGTTTCCTGAGCACTGGGGATCAGGCTGCCAAGGGCAACTATGGGCTCCTTGATCAAAT
CCAGGCCCTTCGCTGGGTGAGTGAGAACATTGCCTTCTTTGGAGGAGATCCCCGTAGAATTACTGTCTTTGGCTCTGGCATTGGTGCATCCTGTGTCAGTCTTCTCACACTGTCTCATCACTCTGAGG
GGCTTTTCCAGAGGGCCATCATCCAAAGTGGCTCAGCGCTATCTAGCTGGGCTGTGAACTACCAACCAGTGAAGTACACCAGCTTGCTCGCAGACAAAGTGGGCTGTAACGTCCTGGACACTGTGGAT
ATGGTGGATTGTCTTCGACAAAAGAGTGCCAAGGAGCTGGTAGAACAGGACATTCAGCCAGCCCGCTACCATGTGGCTTTTGGCCCTGTGATTGATGGTGATGTCATTCCTGATGACCCTGAGATCCT
TATGGAACAGGGAGAGTTCCTCAACTATGATATCATGCTAGGCGTCAACCAGGGTGAGGGTCTCAAGTTTGTGGAAGGGGTGGTGGACCCCGAGGATGGTGTCTCTGGCACTGACTTTGACTACTCTG
TCTCCAATTTTGTGGACAATCTATATGGCTATCCCGAGGGTAAGGACACCCTGCGGGAGACTATCAAGTTCATGTATACAGACTGGGCAGACCGAGACAACCCTGAGACCCGCCGTAAAACACTGGTG
GCACTCTTCACTGACCACCAGTGGGTGGAGCCTTCGGTGGTGACAGCTGATCTGCATGCCCGCTATGGCTCACCCACTTACTTCTACGCCTTCTACCATCACTGCCAGAGCCTCATGAAGCCTGCATG
GTCAGATGCAGCACACGGGGATGAAGTACCCTATGTTTTTGGTGTCCCTATGGTAGGTCCCACTGACCTTTTCCCCTGCAACTTCTCCAAGAATGATGTTATGCTCAGTGCTGTTGTTATGACCTATT
GGACCAACTTTGCCAAGACCGGGGATCCCAACAAGCCGGTACCCCAGGATACCAAGTTCATTCACACCAAGGCCAACCGCTTTGAGGAAGTAGCCTGGTCCAAATACAATCCCCGGGACCAGCTCTAC
CTTCACATCGGGCTGAAACCAAGGGTTCGTGATCATTACCGAGCCACAAAGGTAGCCTTTTGGAAGCACCTGGTACCCCATCTGTACAACCTGCATGACATGTTCCACTATACATCCACGACCACGAA
AGTGCCGCCGCCGGACACCACCCATAGCTCCCACATCACCCGTAGGCCCAACGGCAAGACCTGGAGCACCAAGAGGCCAGCCATCTCACCTGCCTACAGCAATGAGAATGCTCCTGGGTCCTGGAATG
GGGACCAGGATGCAGGGCCACTCCTGGTCGAGAACCCTCGAGACTACTCCACTGAATTAAGTGTCACCATCGCTGTTGGGGCCTCTCTCCTGTTTCTCAATGTGTTGGCCTTTGCTGCTCTCTATTAC
CGTAAGGACAAACGGCGCCAGGAGCCCCTGAGGCAGCCTAGCCCCCAAAGGGGAACTGGTGCCCCAGAATTGGGAACTGCTCCAGAGGAGGAGCTGGCAGCATTACAGTTGGGTCCCACTCACCATGA
GTGTGAGGCCGGCCCCCCACACGACACACTGCGCCTCACAGCATTGCCCGACTACACCCTGACCCTGCGGCGCTCCCCCGATGACATCCCACTCATGACTCCCAACACCATCACTATGATTCCCAATT
CCCTGGTTGGGTTGCAGACCTTGCACCCCTATAACACCTTTGCCGCCGGATTCAACAGCACCGGGCTGCCCCACTCACACTCCACTACCCGTGTATAGCTCTATCCCAGAGCACAACCCATCTCCCAG
ATCCCTCCCTCCCAGATCCACAAACACACATGCACACACATACACATATATGTACACGCACGCACCCACACCCTACAGCAGACCCATCTGCACAAACACAGACAGATGTGGACATGCACCCGCATGTA
CAAAAAAACACAAATCCAGAAGAGAACCTGAATAGGCCCTTCAAATGGGGACACATATGAGTCCTTGGAACCAAGGGCCCATGAAATAGCAGCTGGAGCCAGCTCCTTGAGCCCGACCACAGACACTC
CTGGGGCCCTGGAAGCCACAGCCGGACACCCCCTTGGTGCTTGCCTTCTCGGAACTGCACCGTCTACCAACTGCAGACTCGGGAGCTTTAAAGAGCAGGATAGCTCTTCCTCCCCCAGACTTGGTCTT
TTCTCTGGGTCTTGTTTTTGTTGATTTTTTTAAAAAATTGGAACCAATGCTTTTCCAGCCCATTGAATGCTAAGAGGCTCTGGAAGGGAGGGTTCCAAGATCAGGACTCTCTGGTTCTGGGATTCCCA
ATGTCCATACAATCAGACCAAGGAGAAGGACTCTCCAAGACAGTAACAGATTGGCACAAGACTATGGGGTGAGAGGAGGAAGAGGCTAGCAATGGACAGGGCTGGAGGGCCATCAAGGACAGAGCACC
AGCTGGCTCTTGGGCCTCCCATAGAGGACTGCAGAGCCTACAGGATGGCCTATTTCTTCAAAGGCCAGCAGCATCAGCCTGACTGGAGGAGCCTAGGTTTGGTAAACTAAGTACTGTGGAGGCCCTGA
CCTTATTGGGCCCCTGGGTATATAATCTGGGTTCTGCCTCTACCCTTGGGGACATGATATCAGAAATTTGCCCCATTTTCTTTACAGTCTCTTTGTGTCTGTCATTTCTCTTTCAAAACAGCAGTGGT
TTTTTTTTTTGTTTTTGTTTTTGTTTTTGTTTTTGTTTTTTCGGTTGTTGTTGGCTTTTTTTTTTTTAAGAAAAGTTCTTAAAACACTAACAGAAACCCATGGAGTTTGTCCTTTGTAAAAATTTTAA
ACACAGTGTCTTGATATAAAAATAAAAAATCCAGTTAGCACTCCCAA

hide sequence

RefSeq Acc Id:

XM_006257055 ⟹ XP_006257117

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,495,548 (+)	NCBI
mRatBN7.2	X	66,427,926 - 66,452,659 (+)	NCBI
Rnor_6.0	X	71,199,390 - 71,222,734 (+)	NCBI
Rnor_5.0	X	72,051,846 - 72,075,119 (+)	NCBI

Sequence:

show sequence

ATTGGGCCATGCCCCAGGACTTGAGCCATCACTGGCACAAAAGGAGTTAATGCCAGGGACCGCG
CCCCCCCGTGTCCGGGCACGCGCAGCGCGCCCCCTTGGTGCGCGGGCACAGCAGCCAGGCTGCCGGAGAGCTGATCTCGGGATTCGGGTGCGGAGCCCTTGGCCTGGAGGCGATATGGGTGGTCCGTG
GCCCGGTTCAGTCGTTTGCAGCCGCCTAGGGAACAGGCCTGTCTGGCCCTAAGGGAGCCCTCTTTCGAAGTGGTGGTGCTCGGACGACCTGCTCTCTGCGTGGCTGGGCACCTGTAGGTGTCCCTCGA
GAGCTCAGTTTTGAGGTTCAAGCCAGTGTGGCCATGAAGTGGCTGCCTATTGGGCTGATGCTGTGACCCCGGAGTCTTCCTCTCCTGCCAGTCCCCCTGCCCGGAACATGTGGCTGCAGCTCGGCCTG
CCCTCGTTGTCCCTGAGCCCCACGCCCACAGTTGGCCGGAGCCTGTGCCTCATCCTGTGGTTCCTCAGTTTGGTGCTGAGGGCCAGTACCCAGGCCCCGGCACCCACAGTCAATACTCACTTTGGGAA
ACTAAGGGGTGCCAGAGTACCATTGCCCAGTGAAATCCTGGGTCCTGTGGACCAATACCTGGGGGTACCCTACGCAGCTCCCCCGATCGGCGAGAAACGTTTCCTGCCCCCTGAACCACCCCCATCCT
GGTCGGGCATCCGGAACGCCACACACTTTCCCCCAGTGTGCCCCCAGAACATCCACACAGCTGTGCCCGAAGTCATGCTGCCAGTCTGGTTCACTGCCAACTTGGATATCGTCGCCACTTATATCCAG
GAGCCCAACGAAGATTGCCTCTATCTGAATGTGTATGTGCCCACGGAAGATGACATCCGAGACAGTGGTGCTAAACCTGTCATGGTCTACATCCACGGAGGCTCTTACATGGAAGGAACAGGCAACAT
GATTGACGGCAGCGTTCTTGCAAGTTATGGCAACGTCATCGTCATCACACTCAACTACCGGGTCGGGGTGCTAGGTTTCCTGAGCACTGGGGATCAGGCTGCCAAGGGCAACTATGGGCTCCTTGATC
AAATCCAGGCCCTTCGCTGGGTGAGTGAGAACATTGCCTTCTTTGGAGGAGATCCCCGTAGAATTACTGTCTTTGGCTCTGGCATTGGTGCATCCTGTGTCAGTCTTCTCACACTGTCTCATCACTCT
GAGGGGCTTTTCCAGAGGGCCATCATCCAAAGTGGCTCAGCGCTATCTAGCTGGGCTGTGAACTACCAACCAGTGAAGTACACCAGCTTGCTCGCAGACAAAGTGGGCTGTAACGTCCTGGACACTGT
GGATATGGTGGATTGTCTTCGACAAAAGAGTGCCAAGGAGCTGGTAGAACAGGACATTCAGCCAGCCCGCTACCATGTGGCTTTTGGCCCTGTGATTGATGGTGATGTCATTCCTGATGACCCTGAGA
TCCTTATGGAACAGGGAGAGTTCCTCAACTATGATATCATGCTAGGCGTCAACCAGGGTGAGGGTCTCAAGTTTGTGGAAGGGGTGGTGGACCCCGAGGATGGTGTCTCTGGCACTGACTTTGACTAC
TCTGTCTCCAATTTTGTGGACAATCTATATGGCTATCCCGAGGGTAAGGACACCCTGCGGGAGACTATCAAGTTCATGTATACAGACTGGGCAGACCGAGACAACCCTGAGACCCGCCGTAAAACACT
GGTGGCACTCTTCACTGACCACCAGTGGGTGGAGCCTTCGGTGGTGACAGCTGATCTGCATGCCCGCTATGGCTCACCCACTTACTTCTACGCCTTCTACCATCACTGCCAGAGCCTCATGAAGCCTG
CATGGTCAGATGCAGCACACGGGGATGAAGTACCCTATGTTTTTGGTGTCCCTATGGTAGGTCCCACTGACCTTTTCCCCTGCAACTTCTCCAAGAATGATGTTATGCTCAGTGCTGTTGTTATGACC
TATTGGACCAACTTTGCCAAGACCGGGGATCCCAACAAGCCGGTACCCCAGGATACCAAGTTCATTCACACCAAGGCCAACCGCTTTGAGGAAGTAGCCTGGTCCAAATACAATCCCCGGGACCAGCT
CTACCTTCACATCGGGCTGAAACCAAGGGTTCGTGATCATTACCGAGCCACAAAGGTAGCCTTTTGGAAGCACCTGGTACCCCATCTGTACAACCTGCATGACATGTTCCACTATACATCCACGACCA
CGAAAGTGCCGCCGCCGGACACCACCCATAGCTCCCACATCACCCGTAGGCCCAACGGCAAGACCTGGAGCACCAAGAGGCCAGCCATCTCACCTGCCTACAGCAATGAGAATGCTCCTGGGTCCTGG
AATGGGGACCAGGATGCAGGGCCACTCCTGGTCGAGAACCCTCGAGACTACTCCACTGAATTAAGTGTCACCATCGCTGTTGGGGCCTCTCTCCTGTTTCTCAATGTGTTGGCCTTTGCTGCTCTCTA
TTACCGTAAGGACAAACGGCGCCAGGAGCCCCTGAGGCAGCCTAGCCCCCAAAGGGGAACTGGTGCCCCAGAATTGGGAACTGCTCCAGAGGAGGAGCTGGCAGCATTACAGTTGGGTCCCACTCACC
ATGAGTGTGAGGCCGGCCCCCCACACGACACACTGCGCCTCACAGCATTGCCCGACTACACCCTGACCCTGCGGCGCTCCCCCGATGACATCCCACTCATGACTCCCAACACCATCACTATGATTCCC
AATTCCCTGGTTGGGTTGCAGACCTTGCACCCCTATAACACCTTTGCCGCCGGATTCAACAGCACCGGGCTGCCCCACTCACACTCCACTACCCGTGTATAGCTCTATCCCAGAGCACAACCCATCTC
CCAGATCCCTCCCTCCCAGATCCACAAACACACATGCACACACATACACATATATGTACACGCACGCACCCACACCCTACAGCAGACCCATCTGCACAAACACAGACAGATGTGGACATGCACCCGCA
TGTACAAAAAAACACAAATCCAGAAGAGAACCTGAATAGGCCCTTCAAATGGGGACACATATGAGTCCTTGGAACCAAGGGCCCATGAAATAGCAGCTGGAGCCAGCTCCTTGAGCCCGACCACAGAC
ACTCCTGGGGCCCTGGAAGCCACAGCCGGACACCCCCTTGGTGCTTGCCTTCTCGGAACTGCACCGTCTACCAACTGCAGACTCGGGAGCTTTAAAGAGCAGGATAGCTCTTCCTCCCCCAGACTTGG
TCTTTTCTCTGGGTCTTGTTTTTGTTGATTTTTTTAAAAAATTGGAACCAATGCTTTTCCAGCCCATTGAATGCTAAGAGGCTCTGGAAGGGAGGGTTCCAAGATCAGGACTCTCTGGTTCTGGGATT
CCCAATGTCCATACAATCAGACCAAGGAGAAGGACTCTCCAAGACAGTAACAGATTGGCACAAGACTATGGGGTGAGAGGAGGAAGAGGCTAGCAATGGACAGGGCTGGAGGGCCATCAAGGACAGAG
CACCAGCTGGCTCTTGGGCCTCCCATAGAGGACTGCAGAGCCTACAGGATGGCCTATTTCTTCAAAGGCCAGCAGCATCAGCCTGACTGGAGGAGCCTAGGTTTGGTAAACTAAGTACTGTGGAGGCC
CTGACCTTATTGGGCCCCTGGGTATATAATCTGGGTTCTGCCTCTACCCTTGGGGACATGATATCAGAAATTTGCCCCATTTTCTTTACAGTCTCTTTGTGTCTGTCATTTCTCTTTCAAAACAGCAG
TGGTTTTTTTTTTTGTTTTTGTTTTTGTTTTTGTTTTTGTTTTTTCGGTTGTTGTTGGCTTTTTTTTTTTTAAGAAAAGTTCTTAAAACACTAACAGAAACCCATGGAGTTTGTCCTTTGTAAAAATT
TTAAACACAGTGTCTTGATATAAAAATAAAAAATCCAGTTAGCACTCCCAA

hide sequence

RefSeq Acc Id:

XR_010061164

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI

RefSeq Acc Id:

XR_010061165

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI

RefSeq Acc Id:

XR_010061166

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI

RefSeq Acc Id:

XR_010061167

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI

RefSeq Acc Id:

XR_010061168

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI

RefSeq Acc Id:

XR_010061169

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	70,469,251 - 70,497,380 (+)	NCBI


Protein RefSeqs	NP_001418586	(Get FASTA)	NCBI Sequence Viewer
	NP_001418587	(Get FASTA)	NCBI Sequence Viewer
	NP_599163	(Get FASTA)	NCBI Sequence Viewer
	XP_006257116	(Get FASTA)	NCBI Sequence Viewer
	XP_006257117	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA97871	(Get FASTA)	NCBI Sequence Viewer
	EDL95899	(Get FASTA)	NCBI Sequence Viewer
	EDL95900	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005077
	ENSRNOP00000005102
	ENSRNOP00000068393
GenBank Protein	Q62889	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_599163 ⟸ NM_134336
- Peptide Label:	precursor
- UniProtKB:	Q62889 (UniProtKB/Swiss-Prot), F1LPZ8 (UniProtKB/TrEMBL), A6IQB3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWLQLGLPSLSLSPTPTVGRSLCLILWFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD IVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIP DDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQS LMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY TSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGTGAPELGTAPEEELAALQL GPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV hide sequence

RefSeq Acc Id:

XP_006257116 ⟸ XM_006257054

- Peptide Label:

isoform X1

- Sequence:

show sequence

MWLQLGLPSLSLSPTPTVGRSLCLILWFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD
IVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG
GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLG
VNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFG
VPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITR
RPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGTGAPELGTAPEEELAALQLGPTHHECEAGPPHDTLRLTA
LPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV

hide sequence

RefSeq Acc Id:

XP_006257117 ⟸ XM_006257055

- Peptide Label:

isoform X2

- Sequence:

show sequence

MWLQLGLPSLSLSPTPTVGRSLCLILWFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILG
PVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIV
ITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL
VEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSV
VTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHY
RATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQP
SPQRGTGAPELGTAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV

hide sequence

Ensembl Acc Id:

ENSRNOP00000005077 ⟸ ENSRNOT00000005077

Ensembl Acc Id:

ENSRNOP00000005102 ⟸ ENSRNOT00000005102

Protein Domains

Carboxylesterase type B

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62889-F1-model_v2	AlphaFold	Q62889	1-848	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13701879

Promoter ID:

EPDNEW_R12399

Type:

single initiation site

Name:

Nlgn3_1

Description:

neuroligin 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	71,199,501 - 71,199,561	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-2102	BioCyc
Ensembl Genes	ENSRNOG00000003812	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000005077	ENTREZGENE
	ENSRNOT00000005102	ENTREZGENE
	ENSRNOT00000076168	ENTREZGENE
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot
	CarbesteraseB	UniProtKB/Swiss-Prot
	Carboxylesterase_B_CS	UniProtKB/Swiss-Prot
	Neuroligin/BSAL	UniProtKB/Swiss-Prot
	Nlgn	UniProtKB/Swiss-Prot
KEGG Report	rno:171297	UniProtKB/Swiss-Prot
NCBI Gene	171297	ENTREZGENE
PANTHER	NEUROLIGIN	UniProtKB/Swiss-Prot
Pfam	COesterase	UniProtKB/Swiss-Prot
PhenoGen	Nlgn3	PhenoGen
PRINTS	NEUROLIGIN	UniProtKB/Swiss-Prot
PROSITE	CARBOXYLESTERASE_B_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003812	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot
UniProt	A0A096MK63	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZNW2	ENTREZGENE, UniProtKB/TrEMBL
	A6IQB3	ENTREZGENE, UniProtKB/TrEMBL
	A6IQB4_RAT	UniProtKB/TrEMBL
	D3ZDC0	ENTREZGENE, UniProtKB/TrEMBL
	F1LPZ8	ENTREZGENE, UniProtKB/TrEMBL
	NLGN3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-02-26	Nlgn3	neuroligin 3			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Nlgn3	neuroligin 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Note Type	Note	Reference
gene_domains	contains a large esterase homology domain, a single transmembrane region, and a short cytoplasmic domain	729051
gene_function	binds beta-neurexins	729051

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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