Kcnh7 (potassium voltage-gated channel subfamily H member 7) - Rat Genome Database

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Gene: Kcnh7 (potassium voltage-gated channel subfamily H member 7) Rattus norvegicus
Analyze
Symbol: Kcnh7
Name: potassium voltage-gated channel subfamily H member 7
RGD ID: 621112
Description: Enables inward rectifier potassium channel activity. Involved in circadian rhythm and potassium ion transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Orthologous to human KCNH7 (potassium voltage-gated channel subfamily H member 7); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: eag-related protein 3; ERG-3; erg3; ether-a-go-go-related gene potassium channel 3; ether-a-go-go-related protein 3; potassium channel erg3; potassium channel, voltage gated eag related subfamily H, member 7; potassium voltage-gated channel, subfamily H (eag-related), member 7; voltage-gated inwardly rectifying potassium channel KCNH7; voltage-gated potassium channel subunit Kv11.3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Kcnh7Tn(sb-T2/Bart3)2.295Mcwi  
Genetic Models: F344-Kcnh7Tn(sb-T2/Bart3)2.295Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8367,737,900 - 68,230,950 (-)NCBIGRCr8
mRatBN7.2347,329,338 - 47,822,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl347,338,501 - 47,822,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx350,693,240 - 51,172,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0359,276,771 - 59,756,022 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0357,049,903 - 57,529,711 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0348,662,450 - 49,168,716 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl348,671,079 - 48,831,467 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0355,325,680 - 55,822,973 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,657,361 - 45,153,509 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1344,553,732 - 45,049,881 (-)NCBI
Celera346,979,379 - 47,455,872 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcnh7Ratautistic disorder  ISOKCNH7 (Homo sapiens)8554872ClinVar Annotator: match by term: Autistic behaviorClinVarPMID:18414213

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcnh7Rat(1->4)-beta-D-glucan multiple interactionsISOKcnh7 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KCNH7 mRNACTDPMID:36331819
Kcnh7Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of KCNH7 mRNACTDPMID:29097150
Kcnh7Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Kcnh7Rat3,4-methylenedioxymethamphetamine increases expressionISOKcnh7 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of KCNH7 mRNACTDPMID:20188158
Kcnh7Rat4,4'-sulfonyldiphenol decreases methylationISOKCNH7 (Homo sapiens)6480464bisphenol S results in decreased methylation of KCNH7 geneCTDPMID:31601247
Kcnh7Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of KCNH7 mRNACTDPMID:24780913 and PMID:30047161
Kcnh7Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of KCNH7 mRNACTDPMID:28959563
Kcnh7Rataflatoxin B1 decreases expressionEXP 6480464Aflatoxin B1 results in decreased expression of KCNH7 mRNACTDPMID:23630614
Kcnh7Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of KCNH7 mRNACTDPMID:30047161
Kcnh7Ratbenzo[a]pyrene increases mutagenesisISOKCNH7 (Homo sapiens)6480464Benzo(a)pyrene results in increased mutagenesis of KCNH7 geneCTDPMID:25435355
Kcnh7Ratbenzo[a]pyrene decreases expressionISOKCNH7 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of KCNH7 mRNACTDPMID:32234424
Kcnh7Ratbenzo[a]pyrene increases methylationISOKCNH7 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of KCNH7 3' UTR more ...CTDPMID:27901495
Kcnh7Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of KCNH7 mRNACTDPMID:25181051 more ...
Kcnh7Ratbisphenol A decreases expressionISOKcnh7 (Mus musculus)6480464bisphenol A results in decreased expression of KCNH7 mRNACTDPMID:32156529
Kcnh7Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of KCNH7 geneCTDPMID:28505145
Kcnh7Ratbisphenol F decreases expressionISOKcnh7 (Mus musculus)6480464bisphenol F results in decreased expression of KCNH7 mRNACTDPMID:38685157
Kcnh7RatCuprizon decreases expressionEXP 6480464Cuprizone results in decreased expression of KCNH7 mRNACTDPMID:26577399 and PMID:27523638
Kcnh7Ratdorsomorphin multiple interactionsISOKCNH7 (Homo sapiens)6480464[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...CTDPMID:27188386
Kcnh7Ratdoxorubicin decreases expressionISOKCNH7 (Homo sapiens)6480464Doxorubicin results in decreased expression of KCNH7 mRNACTDPMID:29803840
Kcnh7Ratethanol increases expressionISOKcnh7 (Mus musculus)6480464Ethanol results in increased expression of KCNH7 mRNACTDPMID:30319688

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Biological Process
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcnh7Ratcircadian rhythm  IEP 2314391 RGD 
Kcnh7Ratmonoatomic ion transmembrane transport involved_inIEAUniProtKB-KW:KW-0407 and UniProtKB-KW:KW-08511600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratmonoatomic ion transmembrane transport involved_inIEAGO:00052161600115GO_REF:0000108GOCGO_REF:0000108
Kcnh7Ratmonoatomic ion transport involved_inIEAInterPro:IPR0058211600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratmonoatomic ion transport involved_inIEAUniProtKB-KW:KW-04061600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratpotassium ion transmembrane transport involved_inIEAGO:00052491600115GO_REF:0000108GOCGO_REF:0000108
Kcnh7Ratpotassium ion transmembrane transport involved_inIBAMGI:1341721 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcnh7Ratpotassium ion transmembrane transport involved_inIEAUniProtKB-KW:KW-06311600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratpotassium ion transport  IDA 632747 RGD 
Kcnh7Ratpotassium ion transport involved_inIEAInterPro:IPR0039381600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratpotassium ion transport involved_inIEAUniProtKB-KW:KW-06331600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratpotassium ion transport involved_inIEAInterPro:IPR003938 and InterPro:IPR0039671600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratpotassium ion transport involved_inIEAUniProtKB:Q9NS40 and ensembl:ENSP000003317271600115GO_REF:0000107EnsemblGO_REF:0000107
Kcnh7Ratpotassium ion transport involved_inISOKCNH7 (Homo sapiens)1624291 PMID:32723862RGDPMID:32723862
Kcnh7Ratpotassium ion transport involved_inIDA 2314395PMID:11212207UniProt 
Kcnh7Ratregulation of membrane potential involved_inIBAMGI:1341722 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcnh7Rattransmembrane transport involved_inIEAInterPro:IPR0058211600115GO_REF:0000002InterProGO_REF:0000002
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcnh7Ratmembrane located_inIEAInterPro:IPR003938 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratmembrane located_inIEAInterPro:IPR003938 and InterPro:IPR0058211600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Kcnh7Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratmonoatomic ion channel complex part_ofIEAUniProtKB-KW:KW-08511600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Kcnh7Ratplasma membrane is_active_inIBAFB:FBgn0000535 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcnh7Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcnh7Ratheme binding enablesISOKCNH7 (Homo sapiens)1624291 PMID:32723862RGDPMID:32723862
Kcnh7Ratheme binding enablesIEAUniProtKB:Q9NS40 and ensembl:ENSP000003317271600115GO_REF:0000107EnsemblGO_REF:0000107
Kcnh7Ratinward rectifier potassium channel activity  IDA 1580505 RGD 
Kcnh7Ratinward rectifier potassium channel activity enablesIBAMGI:1341722 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcnh7Ratinward rectifier potassium channel activity enablesIEAUniProtKB:Q9NS40 and ensembl:ENSP000003317271600115GO_REF:0000107EnsemblGO_REF:0000107
Kcnh7Ratinward rectifier potassium channel activity enablesISOKCNH7 (Homo sapiens)1624291 PMID:32723862RGDPMID:32723862
Kcnh7Ratinward rectifier potassium channel activity enablesIDA 2314395PMID:11212207UniProt 
Kcnh7Ratmonoatomic ion channel activity enablesIEAInterPro:IPR0058211600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratmonoatomic ion channel activity enablesIEAARBA:ARBA000263771600115GO_REF:0000117UniProtGO_REF:0000117
Kcnh7Ratpotassium channel activity enablesIEAUniProtKB-KW:KW-06311600115GO_REF:0000043UniProtGO_REF:0000043
Kcnh7Ratpotassium channel activity  IDA 632747 RGD 
Kcnh7Ratprotein-containing complex binding  IDA 2314395heterooligomerizationRGD 
Kcnh7Ratvoltage-gated potassium channel activity  IDA 1580505 RGD 
Kcnh7Ratvoltage-gated potassium channel activity enablesIEAInterPro:IPR003938 and InterPro:IPR0039671600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratvoltage-gated potassium channel activity enablesIEAInterPro:IPR0039381600115GO_REF:0000002InterProGO_REF:0000002
Kcnh7Ratvoltage-gated potassium channel activity enablesIEAARBA:ARBA000264581600115GO_REF:0000117UniProtGO_REF:0000117
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1 to 12 of 12 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Fast erg K+ currents in rat embryonic serotonergic neurones. Hirdes W, etal., J Physiol. 2005 Apr 1;564(Pt 1):33-49. Epub 2005 Jan 27.
3. Rat liver carboxylesterase: cDNA cloning, sequencing, and evidence for a multigene family. Long RM, etal., Biochem Biophys Res Commun 1988 Oct 31;156(2):866-73.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Circadian changes of ether-a-go-go-related-gene (Erg) potassium channel transcripts in the rat pancreas and beta-cell. Muhlbauer E, etal., Cell Mol Life Sci. 2007 Mar;64(6):768-80.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Molecular and functional characterization of ERG, KCNQ, and KCNE subtypes in rat stomach smooth muscle. Ohya S, etal., Am J Physiol Gastrointest Liver Physiol 2002 Feb;282(2):G277-87.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Identification of two nervous system-specific members of the erg potassium channel gene family. Shi W, etal., J Neurosci 1997 Dec 15;17(24):9423-32.
12. Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers. Wimmers S, etal., Pflugers Arch. 2001 Jan;441(4):450-5.
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PMID:10718922   PMID:18162604   PMID:22871113  



Kcnh7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8367,737,900 - 68,230,950 (-)NCBIGRCr8
mRatBN7.2347,329,338 - 47,822,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl347,338,501 - 47,822,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx350,693,240 - 51,172,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0359,276,771 - 59,756,022 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0357,049,903 - 57,529,711 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0348,662,450 - 49,168,716 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl348,671,079 - 48,831,467 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0355,325,680 - 55,822,973 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,657,361 - 45,153,509 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1344,553,732 - 45,049,881 (-)NCBI
Celera346,979,379 - 47,455,872 (-)NCBICelera
Cytogenetic Map3q21NCBI
KCNH7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382162,371,407 - 162,838,767 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2162,371,407 - 162,838,767 (-)EnsemblGRCh38hg38GRCh38
GRCh372163,227,917 - 163,695,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362162,936,163 - 163,403,486 (-)NCBINCBI36Build 36hg18NCBI36
Build 342163,105,265 - 163,520,747NCBI
Celera2156,838,249 - 157,305,494 (-)NCBICelera
Cytogenetic Map2q24.2NCBI
HuRef2155,110,219 - 155,577,951 (-)NCBIHuRef
CHM1_12163,233,802 - 163,700,825 (-)NCBICHM1_1
T2T-CHM13v2.02162,828,067 - 163,295,631 (-)NCBIT2T-CHM13v2.0
Kcnh7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39262,524,428 - 63,014,980 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl262,523,758 - 63,014,631 (-)EnsemblGRCm39 Ensembl
GRCm38262,693,410 - 63,184,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl262,693,414 - 63,184,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv37262,541,003 - 63,022,344 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36262,503,787 - 62,990,422 (-)NCBIMGSCv36mm8
Celera264,395,436 - 64,884,597 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map236.5NCBI
Kcnh7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544911,052,777 - 11,491,379 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544911,052,767 - 11,495,193 (+)NCBIChiLan1.0ChiLan1.0
KCNH7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21365,057,056 - 65,538,641 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B65,072,031 - 65,553,616 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B49,657,021 - 50,140,216 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B167,033,119 - 167,507,053 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B167,033,119 - 167,506,691 (-)Ensemblpanpan1.1panPan2
KCNH7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1367,781,323 - 8,260,893 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl367,649,727 - 8,261,048 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha367,924,497 - 8,405,370 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0367,912,971 - 8,393,200 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl367,921,442 - 8,393,196 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1367,931,129 - 8,410,170 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0367,972,137 - 8,444,518 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0368,079,838 - 8,559,344 (-)NCBIUU_Cfam_GSD_1.0
Kcnh7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303124,933,273 - 125,395,993 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646916,222,005 - 16,691,596 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646916,221,750 - 16,674,526 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNH7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1569,059,870 - 69,555,049 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11569,053,456 - 69,555,144 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21576,700,311 - 77,198,048 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNH7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11047,786,795 - 48,248,348 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1047,785,318 - 47,950,144 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040151,280,149 - 151,747,051 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnh7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247322,684,948 - 3,148,951 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247322,684,719 - 3,150,749 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Kcnh7
4099 total Variants

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:115
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000009920
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 55 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33819223350749747Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)32749462150302886Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat

1 to 10 of 55 rows
D3Got33  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2347,769,862 - 47,770,067 (+)MAPPERmRatBN7.2
Rnor_6.0349,115,270 - 49,115,474NCBIRnor6.0
Rnor_5.0355,769,295 - 55,769,499UniSTSRnor5.0
RGSC_v3.4345,100,293 - 45,100,498RGDRGSC3.4
RGSC_v3.4345,100,294 - 45,100,498UniSTSRGSC3.4
RGSC_v3.1344,996,666 - 44,996,870RGD
Celera347,403,621 - 47,403,821UniSTS
RH 3.4 Map3603.83UniSTS
RH 3.4 Map3603.83RGD
RH 2.0 Map3380.1RGD
Cytogenetic Map3q21UniSTS
D3Got307  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2347,364,366 - 47,364,545 (+)MAPPERmRatBN7.2
Rnor_6.0348,697,897 - 48,698,075NCBIRnor6.0
Rnor_5.0355,361,074 - 55,361,252UniSTSRnor5.0
Celera347,005,192 - 47,005,368UniSTS
Cytogenetic Map3q21UniSTS
AU047731  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8368,066,386 - 68,066,624 (+)Marker Load Pipeline
mRatBN7.2347,657,829 - 47,658,067 (+)MAPPERmRatBN7.2
Rnor_6.0349,003,513 - 49,003,750NCBIRnor6.0
Rnor_5.0355,657,751 - 55,657,988UniSTSRnor5.0
RGSC_v3.4344,978,788 - 44,979,025UniSTSRGSC3.4
Celera347,297,713 - 47,297,934UniSTS
Cytogenetic Map3q21UniSTS


This gene Kcnh7 is modified in the following models/strains:




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 3 24 108 39 38 17 12 17 6 102 51 93 25 44 21



Ensembl Acc Id: ENSRNOT00000009920   ⟹   ENSRNOP00000009920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl347,338,501 - 47,497,311 (-)Ensembl
Rnor_6.0 Ensembl348,671,241 - 48,831,417 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085246   ⟹   ENSRNOP00000072574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl347,338,501 - 47,497,311 (-)Ensembl
Rnor_6.0 Ensembl348,671,079 - 48,831,467 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095298   ⟹   ENSRNOP00000078806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl347,338,501 - 47,497,866 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112058   ⟹   ENSRNOP00000078922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl347,338,501 - 47,822,195 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119314   ⟹   ENSRNOP00000078968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl347,425,115 - 47,822,195 (-)Ensembl
RefSeq Acc Id: NM_131912   ⟹   NP_571987
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8367,747,063 - 68,230,671 (-)NCBI
mRatBN7.2347,338,501 - 47,822,122 (-)NCBI
Rnor_6.0348,671,241 - 49,168,639 (-)NCBI
Rnor_5.0355,325,680 - 55,822,973 (-)NCBI
RGSC_v3.4344,657,361 - 45,153,509 (-)RGD
Celera346,979,379 - 47,455,872 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234269   ⟹   XP_006234331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8367,737,900 - 68,230,950 (-)NCBI
mRatBN7.2347,329,338 - 47,821,992 (-)NCBI
Rnor_6.0348,662,450 - 49,168,716 (-)NCBI
Rnor_5.0355,325,680 - 55,822,973 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591438   ⟹   XP_017446927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8367,737,900 - 68,230,950 (-)NCBI
mRatBN7.2347,329,338 - 47,821,992 (-)NCBI
Rnor_6.0348,662,450 - 49,168,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063283031   ⟹   XP_063139101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8367,737,900 - 68,230,950 (-)NCBI
RefSeq Acc Id: XM_063283033   ⟹   XP_063139103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8367,737,900 - 68,230,950 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_571987   ⟸   NM_131912
- UniProtKB: O54852 (UniProtKB/Swiss-Prot),   A6HLW2 (UniProtKB/TrEMBL),   A0A8I5ZLI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234331   ⟸   XM_006234269
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446927   ⟸   XM_017591438
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UHF2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072574   ⟸   ENSRNOT00000085246
Ensembl Acc Id: ENSRNOP00000009920   ⟸   ENSRNOT00000009920
Cyclic nucleotide-binding   Ion transport   PAC   PAS

Name Modeler Protein Id AA Range Protein Structure
AF-O54852-F1-model_v2 AlphaFold O54852 1-1195 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 43 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-49582 BioCyc
Ensembl Genes ENSRNOG00000007528 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009920 ENTREZGENE
  ENSRNOT00000085246 ENTREZGENE
  ENSRNOT00000112058 ENTREZGENE
  ENSRNOT00000112058.1 UniProtKB/Swiss-Prot
  ENSRNOT00000119314 ENTREZGENE
Gene3D-CATH 1.10.1200.260 UniProtKB/Swiss-Prot
  1.10.287.70 UniProtKB/Swiss-Prot
  2.60.120.10 UniProtKB/Swiss-Prot
  PAS domain UniProtKB/Swiss-Prot
InterPro cNMP-bd-like UniProtKB/Swiss-Prot
  cNMP-bd_dom UniProtKB/Swiss-Prot
  Ion_trans_dom UniProtKB/Swiss-Prot
  K_chnl_volt-dep_EAG/ELK/ERG UniProtKB/Swiss-Prot
  K_chnl_volt-dep_ERG UniProtKB/Swiss-Prot
  KCNH_channel UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
  PAS-like_dom_sf UniProtKB/Swiss-Prot
  RmlC-like_jellyroll UniProtKB/Swiss-Prot
KEGG Report rno:170739 UniProtKB/Swiss-Prot
NCBI Gene 170739 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 7 UniProtKB/Swiss-Prot
  VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL UniProtKB/Swiss-Prot
Pfam cNMP_binding UniProtKB/Swiss-Prot
  Ion_trans UniProtKB/Swiss-Prot
  PAS_9 UniProtKB/Swiss-Prot
PhenoGen Kcnh7 PhenoGen
PRINTS EAGCHANLFMLY UniProtKB/Swiss-Prot
  ERGCHANNEL UniProtKB/Swiss-Prot
PROSITE CNMP_BINDING_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007528 RatGTEx
SMART cNMP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51206 UniProtKB/Swiss-Prot
  SSF55785 UniProtKB/Swiss-Prot
  Voltage-gated potassium channels UniProtKB/Swiss-Prot
UniProt A0A0G2K3B8 ENTREZGENE, UniProtKB/TrEMBL
  A0A0H2UHF2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZLI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZLU2_RAT UniProtKB/TrEMBL
1 to 40 of 43 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Kcnh7  potassium voltage-gated channel, subfamily H (eag-related), member 7  erg3  potassium channel erg3  Symbol and Name updated 1299863 APPROVED
2002-08-07 erg3  potassium channel erg3      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression expressed in the fundus and antrum of the stomach 625508
gene_expression enriched in the nervous system 632748
gene_product 374 bp 625508
gene_product member of the erg potassium channel gene family 632748