Ubqln1 (ubiquilin 1) - Rat Genome Database

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Gene: Ubqln1 (ubiquilin 1) Rattus norvegicus
Analyze
Symbol: Ubqln1
Name: ubiquilin 1
RGD ID: 620745
Description: Enables protein domain specific binding activity. Predicted to be involved in several processes, including macroautophagy; positive regulation of protein metabolic process; and proteolysis involved in protein catabolic process. Predicted to be located in several cellular components, including aggresome; endoplasmic reticulum; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Predicted to be active in autophagosome and cytosol. Orthologous to human UBQLN1 (ubiquilin 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Da41; PLIC-1; protein linking IAP with cytoskeleton 1; ubiquilin-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,438,456 - 6,482,498 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl176,444,124 - 6,482,499 (+)EnsemblGRCr8
mRatBN7.2176,439,002 - 6,477,096 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,439,002 - 6,477,090 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx176,462,325 - 6,499,084 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0177,994,298 - 8,031,031 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,458,709 - 6,495,468 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0176,840,441 - 6,878,842 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,840,463 - 6,878,844 (+)Ensemblrn6Rnor6.0
Rnor_5.0179,044,221 - 9,081,483 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41712,370,389 - 12,418,868 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,548,513 - 6,585,082 (+)NCBICelera
RGSC_v3.11712,370,388 - 12,418,868 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[k]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium sulfate  (ISO)
calcidiol  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dorsomorphin  (ISO)
enzyme inhibitor  (ISO)
erianin  (ISO)
ethanol  (ISO)
flutamide  (EXP)
furan  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrazine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dichloride  (EXP)
metacetamol  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
ochratoxin A  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
toluene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
aggresome  (IEA,ISO,ISS)
autophagosome  (IBA,IEA,ISO,ISS)
cytoplasm  (IEA,ISO,ISS)
cytoplasmic vesicle  (IEA)
cytosol  (IBA,IEA,ISO)
endoplasmic reticulum  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)
perinuclear region of cytoplasm  (IEA,ISO,ISS)
plasma membrane  (IEA,ISO,ISS)
proteasome complex  (IEA)
protein-containing complex  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. Interaction of DA41, a DAN-binding protein, with the epidermal growth factor-like protein, S(1-5). Ozaki T, etal., Biochem Biophys Res Commun. 1997 Aug 18;237(2):245-50.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Characterization of ubiquilin 1, an mTOR-interacting protein. Wu S, etal., Biochim Biophys Acta 2002 Jan 30;1542(1-3):41-56.
Additional References at PubMed
PMID:9303440   PMID:11528422   PMID:12095988   PMID:12470953   PMID:12634373   PMID:15147878   PMID:15489334   PMID:16159959   PMID:16189514   PMID:16713569   PMID:18307982   PMID:19822669  
PMID:20529957   PMID:21143716   PMID:21695056   PMID:21852239   PMID:22847417   PMID:22871113   PMID:23307288   PMID:23459205   PMID:25416956   PMID:26415648   PMID:26514267  


Genomics

Comparative Map Data
Ubqln1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,438,456 - 6,482,498 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl176,444,124 - 6,482,499 (+)EnsemblGRCr8
mRatBN7.2176,439,002 - 6,477,096 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,439,002 - 6,477,090 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx176,462,325 - 6,499,084 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0177,994,298 - 8,031,031 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,458,709 - 6,495,468 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0176,840,441 - 6,878,842 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,840,463 - 6,878,844 (+)Ensemblrn6Rnor6.0
Rnor_5.0179,044,221 - 9,081,483 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41712,370,389 - 12,418,868 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,548,513 - 6,585,082 (+)NCBICelera
RGSC_v3.11712,370,388 - 12,418,868 (+)NCBI
Cytogenetic Map17p14NCBI
UBQLN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38983,659,968 - 83,707,958 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl983,657,386 - 83,707,993 (-)Ensemblhg38GRCh38
GRCh37986,274,883 - 86,322,873 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36985,464,699 - 85,512,773 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34983,505,905 - 83,552,422NCBI
Celera956,844,906 - 56,893,172 (-)NCBICelera
Cytogenetic Map9q21.32NCBI
HuRef956,100,224 - 56,148,493 (-)NCBIHuRef
CHM1_1986,421,618 - 86,469,907 (-)NCBICHM1_1
T2T-CHM13v2.0995,809,692 - 95,857,669 (-)NCBIT2T-CHM13v2.0
Ubqln1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,323,970 - 58,363,467 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,323,970 - 58,363,467 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381358,176,156 - 58,215,653 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,176,156 - 58,215,653 (-)Ensemblmm10GRCm38
MGSCv371358,277,517 - 58,317,014 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361358,185,785 - 58,225,215 (-)NCBIMGSCv36mm8
Celera1359,238,584 - 59,277,865 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.95NCBI
Ubqln1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554323,575,272 - 3,616,691 (+)Ensembl
ChiLan1.0NW_0049554323,575,034 - 3,617,029 (+)NCBIChiLan1.0ChiLan1.0
UBQLN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21182,819,039 - 82,867,380 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1982,824,982 - 82,873,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0941,170,416 - 41,218,656 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1982,597,507 - 82,645,587 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl982,597,507 - 82,645,587 (-)EnsemblpanPan2panpan1.1
UBQLN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1175,767,345 - 75,812,278 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl175,767,188 - 75,838,051 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha176,417,095 - 76,461,954 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0176,068,847 - 76,113,777 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,068,563 - 76,139,333 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1175,882,246 - 75,927,063 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0175,647,432 - 75,692,286 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,348,320 - 76,393,178 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ubqln1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947122,436,790 - 122,481,818 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936828542,407 - 588,679 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936828543,651 - 588,673 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBQLN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1031,275,868 - 31,317,516 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11031,275,916 - 31,317,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21035,363,230 - 35,404,196 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBQLN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11294,462,867 - 94,512,313 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1294,461,972 - 94,511,747 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603882,876,902 - 82,926,074 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubqln1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248096,436,658 - 6,487,251 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248096,434,842 - 6,487,442 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ubqln1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11479,910,172 - 79,949,428 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ubqln1
197 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:26
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000061233
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
D17Got8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,458,053 - 6,458,282 (+)MAPPERmRatBN7.2
Rnor_6.0176,859,513 - 6,859,741NCBIRnor6.0
Rnor_5.0179,062,556 - 9,062,784UniSTSRnor5.0
RGSC_v3.41712,389,080 - 12,389,309RGDRGSC3.4
RGSC_v3.41712,389,081 - 12,389,309UniSTSRGSC3.4
Celera176,567,416 - 6,567,638UniSTS
RGSC_v3.11712,389,081 - 12,389,309RGD
RH 3.4 Map1773.4UniSTS
RH 3.4 Map1773.4RGD
RH 2.0 Map1757.8RGD
Cytogenetic Map17p14UniSTS
RH134479  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,476,785 - 6,476,996 (+)MAPPERmRatBN7.2
Rnor_6.0176,878,537 - 6,878,747NCBIRnor6.0
Rnor_5.0179,081,178 - 9,081,388UniSTSRnor5.0
RGSC_v3.41712,419,910 - 12,420,120UniSTSRGSC3.4
Celera176,586,124 - 6,586,334UniSTS
RH 3.4 Map1753.3UniSTS
Cytogenetic Map17p14UniSTS
RH137400  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,447,509 - 6,447,716 (+)MAPPERmRatBN7.2
Rnor_6.0176,848,970 - 6,849,176NCBIRnor6.0
Rnor_5.0179,052,014 - 9,052,220UniSTSRnor5.0
RGSC_v3.41712,378,538 - 12,378,744UniSTSRGSC3.4
Celera176,556,882 - 6,557,088UniSTS
RH 3.4 Map1759.7UniSTS
Cytogenetic Map17p14UniSTS
AA875206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,475,466 - 6,475,679 (+)MAPPERmRatBN7.2
Rnor_6.0176,877,218 - 6,877,430NCBIRnor6.0
Rnor_5.0179,079,859 - 9,080,071UniSTSRnor5.0
RGSC_v3.41712,418,591 - 12,418,803UniSTSRGSC3.4
Celera176,584,805 - 6,585,017UniSTS
RH 3.4 Map1769.9UniSTS
Cytogenetic Map17p14UniSTS
RH136282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,475,285 - 6,475,480 (+)MAPPERmRatBN7.2
Rnor_6.0176,877,037 - 6,877,231NCBIRnor6.0
Rnor_5.0179,079,678 - 9,079,872UniSTSRnor5.0
RGSC_v3.41712,418,410 - 12,418,604UniSTSRGSC3.4
Celera176,584,624 - 6,584,818UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000061233   ⟹   ENSRNOP00000057944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl176,444,403 - 6,482,499 (+)Ensembl
mRatBN7.2 Ensembl176,439,002 - 6,477,090 (+)Ensembl
Rnor_6.0 Ensembl176,840,463 - 6,878,844 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120206   ⟹   ENSRNOP00000084505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl176,444,124 - 6,482,496 (+)Ensembl
mRatBN7.2 Ensembl176,439,029 - 6,475,733 (+)Ensembl
RefSeq Acc Id: NM_053747   ⟹   NP_446199
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,444,440 - 6,481,151 (+)NCBI
mRatBN7.2176,439,029 - 6,475,744 (+)NCBI
Rnor_6.0176,840,490 - 6,877,495 (+)NCBI
Rnor_5.0179,044,221 - 9,081,483 (+)NCBI
RGSC_v3.41712,370,389 - 12,418,868 (+)RGD
Celera176,548,513 - 6,585,082 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253551   ⟹   XP_006253613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,438,456 - 6,482,498 (+)NCBI
mRatBN7.2176,439,002 - 6,477,093 (+)NCBI
Rnor_6.0176,840,441 - 6,878,842 (+)NCBI
Rnor_5.0179,044,221 - 9,081,483 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_446199 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253613 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH72477 (Get FASTA)   NCBI Sequence Viewer  
  BAA92267 (Get FASTA)   NCBI Sequence Viewer  
  EDL93918 (Get FASTA)   NCBI Sequence Viewer  
  EDL93919 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057944
  ENSRNOP00000084505
GenBank Protein Q9JJP9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446199   ⟸   NM_053747
- UniProtKB: Q6IN34 (UniProtKB/Swiss-Prot),   Q9JJP9 (UniProtKB/Swiss-Prot),   A0A8I5ZXD7 (UniProtKB/TrEMBL),   A6KAL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253613   ⟸   XM_006253551
- Peptide Label: isoform X1
- UniProtKB: Q9JJP9 (UniProtKB/Swiss-Prot),   Q6IN34 (UniProtKB/Swiss-Prot),   A0A140TAI1 (UniProtKB/TrEMBL),   A6KAL1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057944   ⟸   ENSRNOT00000061233
Ensembl Acc Id: ENSRNOP00000084505   ⟸   ENSRNOT00000120206
Protein Domains
STI1   UBA   Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JJP9-F1-model_v2 AlphaFold Q9JJP9 1-582 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700283
Promoter ID:EPDNEW_R10806
Type:initiation region
Name:Ubqln1_1
Description:ubiquilin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0176,840,451 - 6,840,511EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620745 AgrOrtholog
BioCyc Gene G2FUF-10335 BioCyc
Ensembl Genes ENSRNOG00000019282 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000061233 ENTREZGENE
  ENSRNOT00000120206 ENTREZGENE
Gene3D-CATH 1.10.260.100 UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7103662 IMAGE-MGC_LOAD
InterPro STI1_HS-bd UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  UBA-like_sf UniProtKB/Swiss-Prot
  Ubiquilin UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
  Ubiquitin_dom UniProtKB/Swiss-Prot
KEGG Report rno:114590 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91558 IMAGE-MGC_LOAD
NCBI Gene 114590 ENTREZGENE
PANTHER UBIQUILIN UniProtKB/Swiss-Prot
  UBIQUILIN-1 UniProtKB/Swiss-Prot
Pfam UBA UniProtKB/Swiss-Prot
  ubiquitin UniProtKB/Swiss-Prot
  UBQLN1 UniProtKB/Swiss-Prot
PhenoGen Ubqln1 PhenoGen
PROSITE UBA UniProtKB/Swiss-Prot
  UBIQUITIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019282 RatGTEx
SMART STI1 UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  UBQ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46934 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A140TAI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXD7 ENTREZGENE, UniProtKB/TrEMBL
  A6KAL0 ENTREZGENE, UniProtKB/TrEMBL
  A6KAL1 ENTREZGENE, UniProtKB/TrEMBL
  Q6IN34 ENTREZGENE
  Q9JJP9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6IN34 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Ubqln1  ubiquilin 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Ubqln1  ubiquilin 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to non-catalytic region of mTOR kinase 724762