B4galnt1 (beta-1,4-N-acetyl-galactosaminyl transferase 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: B4galnt1 (beta-1,4-N-acetyl-galactosaminyl transferase 1) Rattus norvegicus
Analyze
Symbol: B4galnt1
Name: beta-1,4-N-acetyl-galactosaminyl transferase 1
RGD ID: 620490
Description: Enables (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity. Involved in ganglioside biosynthetic process. Located in Golgi membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 26. Orthologous to human B4GALNT1 (beta-1,4-N-acetyl-galactosaminyltransferase 1); PARTICIPATES IN ganglioside metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: (N-acetylneuraminyl)-galactosylglucosylceramide; beta-1,4 N-acetylgalactosaminyltransferase 1; beta-4N-acetylgalactosaminyltransferase; GA2 synthase; Galgt1; GalNAc-T; GD2 synthase; GM2 synthase; GM2/GD2 synthase; MGC93424; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,873,909 - 64,881,512 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl764,874,022 - 64,881,516 (+)EnsemblGRCr8
mRatBN7.2762,988,429 - 62,996,190 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl762,988,930 - 62,996,190 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx764,878,576 - 64,885,491 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,080,980 - 67,087,895 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,882,067 - 66,888,975 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,439,273 - 70,459,556 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,452,579 - 70,459,880 (+)Ensemblrn6Rnor6.0
Rnor_5.0770,616,836 - 70,637,197 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,120,782 - 67,127,697 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,130,756 - 60,137,671 (+)NCBICelera
RGSC_v3.1767,141,511 - 67,148,426 (+)NCBI
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
choline  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) chloride  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (EXP)
gentamycin  (EXP)
inulin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
Moniliformin  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxycodone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. beta 1-4N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta 1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F. Hidari JK, etal., Biochem J 1994 Nov 1;303 ( Pt 3):957-65.
4. The c-series gangliosides GT3, GT2 and GP1c are formed in rat liver Golgi by the same set of glycosyltransferases that catalyse the biosynthesis of asialo-, a- and b-series gangliosides. Iber H, etal., Glycobiology. 1992 Apr;2(2):137-42. doi: 10.1093/glycob/2.2.137.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides. Nagata Y, etal., J Biol Chem 1992 Jun 15;267(17):12082-9.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. Both GA2, GM2, and GD2 synthases and GM1b, GD1a, and GT1b synthases are single enzymes in Golgi vesicles from rat liver. Pohlentz G, etal., Proc Natl Acad Sci U S A. 1988 Oct;85(19):7044-8. doi: 10.1073/pnas.85.19.7044.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7487055   PMID:7890749   PMID:8855236   PMID:10021458   PMID:15489334   PMID:18308723  


Genomics

Comparative Map Data
B4galnt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,873,909 - 64,881,512 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl764,874,022 - 64,881,516 (+)EnsemblGRCr8
mRatBN7.2762,988,429 - 62,996,190 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl762,988,930 - 62,996,190 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx764,878,576 - 64,885,491 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,080,980 - 67,087,895 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,882,067 - 66,888,975 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,439,273 - 70,459,556 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,452,579 - 70,459,880 (+)Ensemblrn6Rnor6.0
Rnor_5.0770,616,836 - 70,637,197 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,120,782 - 67,127,697 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,130,756 - 60,137,671 (+)NCBICelera
RGSC_v3.1767,141,511 - 67,148,426 (+)NCBI
Cytogenetic Map7q22NCBI
B4GALNT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,623,409 - 57,633,201 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,623,409 - 57,633,239 (-)Ensemblhg38GRCh38
GRCh371258,017,192 - 58,026,984 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,305,818 - 56,313,252 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341256,305,944 - 56,313,251NCBI
Celera1257,675,366 - 57,682,800 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1255,057,363 - 55,064,728 (-)NCBIHuRef
CHM1_11257,987,494 - 57,994,836 (-)NCBICHM1_1
T2T-CHM13v2.01257,591,628 - 57,601,420 (-)NCBIT2T-CHM13v2.0
B4galnt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,001,025 - 127,008,209 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,001,094 - 127,008,199 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3810127,165,156 - 127,172,340 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,165,225 - 127,172,330 (+)Ensemblmm10GRCm38
MGSCv3710126,602,281 - 126,609,386 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610126,568,174 - 126,575,279 (+)NCBIMGSCv36mm8
Celera10129,558,182 - 129,565,363 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
B4galnt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,350,244 - 5,360,965 (-)Ensembl
ChiLan1.0NW_0049554585,351,924 - 5,361,755 (-)NCBIChiLan1.0ChiLan1.0
B4GALNT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,707,796 - 36,717,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,704,569 - 36,714,327 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,293,531 - 31,303,341 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,553,174 - 31,562,988 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,553,671 - 31,562,988 (+)EnsemblpanPan2panpan1.1
B4GALNT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,703,846 - 1,756,837 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,703,169 - 1,709,994 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha101,766,846 - 1,820,023 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0101,713,025 - 1,766,212 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,713,029 - 1,719,832 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,690,802 - 1,743,968 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,932,513 - 1,985,865 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0102,057,788 - 2,110,916 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
B4galnt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,093,575 - 57,099,823 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,770,930 - 1,777,173 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,770,412 - 1,777,152 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B4GALNT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,889,656 - 22,897,508 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1522,889,654 - 22,897,386 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
B4GALNT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,533,485 - 53,541,915 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,530,886 - 53,540,178 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037192,420,656 - 192,427,853 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B4galnt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,329,296 - 10,337,283 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462480210,329,295 - 10,337,205 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
B4galnt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11205,601,491 - 205,608,488 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in B4galnt1
80 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:77
Count of miRNA genes:57
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000046099
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
B4galnt1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2762,990,091 - 62,990,920 (+)MAPPERmRatBN7.2
Rnor_6.0770,453,458 - 70,454,286NCBIRnor6.0
Rnor_5.0770,631,099 - 70,631,927UniSTSRnor5.0
RGSC_v3.4767,121,599 - 67,122,427UniSTSRGSC3.4
Celera760,131,573 - 60,132,401UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
19 13 74 181 91 90 59 154 59 6 467 271 22 152 110 106 31 27 27

Sequence


Ensembl Acc Id: ENSRNOT00000046099   ⟹   ENSRNOP00000048586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,874,058 - 64,881,511 (+)Ensembl
mRatBN7.2 Ensembl762,989,275 - 62,996,189 (+)Ensembl
Rnor_6.0 Ensembl770,452,579 - 70,459,880 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097144   ⟹   ENSRNOP00000078917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,874,022 - 64,881,516 (+)Ensembl
mRatBN7.2 Ensembl762,988,930 - 62,996,190 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104089   ⟹   ENSRNOP00000088949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,874,058 - 64,881,511 (+)Ensembl
mRatBN7.2 Ensembl762,990,203 - 62,996,190 (+)Ensembl
RefSeq Acc Id: NM_022860   ⟹   NP_074051
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,874,597 - 64,881,512 (+)NCBI
mRatBN7.2762,989,275 - 62,996,190 (+)NCBI
Rnor_6.0770,452,641 - 70,459,556 (+)NCBI
Rnor_5.0770,616,836 - 70,637,197 (+)NCBI
RGSC_v3.4767,120,782 - 67,127,697 (+)RGD
Celera760,130,756 - 60,137,671 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241497   ⟹   XP_006241559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,873,961 - 64,881,512 (+)NCBI
mRatBN7.2762,988,715 - 62,996,190 (+)NCBI
Rnor_6.0770,452,447 - 70,459,556 (+)NCBI
Rnor_5.0770,616,836 - 70,637,197 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079858   ⟹   XP_038935786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,873,960 - 64,881,512 (+)NCBI
mRatBN7.2762,988,529 - 62,996,190 (+)NCBI
RefSeq Acc Id: XM_063264214   ⟹   XP_063120284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,873,955 - 64,881,512 (+)NCBI
RefSeq Acc Id: XM_063264215   ⟹   XP_063120285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,873,961 - 64,881,512 (+)NCBI
RefSeq Acc Id: XM_063264216   ⟹   XP_063120286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,873,961 - 64,881,512 (+)NCBI
RefSeq Acc Id: XR_001838716
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,873,909 - 64,878,985 (+)NCBI
mRatBN7.2762,988,429 - 62,993,755 (+)NCBI
Rnor_6.0770,452,429 - 70,457,071 (+)NCBI
Sequence:
RefSeq Acc Id: NP_074051   ⟸   NM_022860
- UniProtKB: Q10468 (UniProtKB/Swiss-Prot),   A6HQS8 (UniProtKB/TrEMBL),   A0A8L2QP76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241559   ⟸   XM_006241497
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZLQ7 (UniProtKB/TrEMBL),   A0A8L2QP76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048586   ⟸   ENSRNOT00000046099
RefSeq Acc Id: XP_038935786   ⟸   XM_039079858
- Peptide Label: isoform X1
- UniProtKB: Q10468 (UniProtKB/Swiss-Prot),   A0A8L2QP76 (UniProtKB/TrEMBL),   A6HQS8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078917   ⟸   ENSRNOT00000097144
Ensembl Acc Id: ENSRNOP00000088949   ⟸   ENSRNOT00000104089
RefSeq Acc Id: XP_063120284   ⟸   XM_063264214
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QP76 (UniProtKB/TrEMBL),   A6HQS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120285   ⟸   XM_063264215
- Peptide Label: isoform X3
- UniProtKB: A0A8L2QP76 (UniProtKB/TrEMBL),   A0A8I5ZLQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120286   ⟸   XM_063264216
- Peptide Label: isoform X1
- UniProtKB: Q10468 (UniProtKB/Swiss-Prot),   A0A8L2QP76 (UniProtKB/TrEMBL),   A6HQS8 (UniProtKB/TrEMBL)
Protein Domains
Glycosyltransferase 2-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q10468-F1-model_v2 AlphaFold Q10468 1-533 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620490 AgrOrtholog
BioCyc Gene G2FUF-33762 BioCyc
BioCyc Pathway PWY-7836 [ganglio-series glycosphingolipids biosynthesis] BioCyc
BioCyc Pathway Image PWY-7836 BioCyc
Ensembl Genes ENSRNOG00000004839 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000097144 ENTREZGENE
  ENSRNOT00000104089 ENTREZGENE
Gene3D-CATH Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7133837 IMAGE-MGC_LOAD
InterPro Glyco_trans_2-like UniProtKB/Swiss-Prot
  GM2_synthase UniProtKB/Swiss-Prot
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot
KEGG Report rno:64828 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93424 IMAGE-MGC_LOAD
NCBI Gene 64828 ENTREZGENE
PANTHER BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 1 UniProtKB/Swiss-Prot
  GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam Glycos_transf_2 UniProtKB/Swiss-Prot
PhenoGen B4galnt1 PhenoGen
PIRSF GM2_GD2_synthase UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004839 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot
UniProt A0A8I5ZLQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8U0_RAT UniProtKB/TrEMBL
  A0A8L2QP76 ENTREZGENE, UniProtKB/TrEMBL
  A6HQS6 ENTREZGENE, UniProtKB/TrEMBL
  A6HQS7_RAT UniProtKB/TrEMBL
  A6HQS8 ENTREZGENE, UniProtKB/TrEMBL
  A6HQS9_RAT UniProtKB/TrEMBL
  A6HQT0_RAT UniProtKB/TrEMBL
  B4GN1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 B4galnt1  beta-1,4-N-acetyl-galactosaminyl transferase 1  Galgt1  UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase  Symbol and Name updated 1299863 APPROVED
2005-01-20 Galgt1  UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase    beta-4N-acetylgalactosaminyltransferase  Name updated 1299863 APPROVED
2002-08-07 Galgt1  beta-4N-acetylgalactosaminyltransferase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression strongly expressed in rat brain, testis, and spleen  
gene_function catalyses the formation of asialo-GM2, GM2, and GD2 631865
gene_homology 88% similar to the human GALGT gene 631865
gene_protein typical type II membrane protein