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Gene: Cand2 (cullin-associated and neddylation-dissociated 2 (putative)) Rattus norvegicus

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Symbol:

Cand2

Name:

cullin-associated and neddylation-dissociated 2 (putative)

RGD ID:

620480

Description:

Enables TBP-class protein binding activity. Predicted to be involved in SCF complex assembly and protein ubiquitination. Predicted to be located in cytosol. Predicted to be active in nucleus. Orthologous to human CAND2 (cullin associated and neddylation dissociated 2 (putative)); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cullin-associated and neddylation-dissociated protein 2; cullin-associated NEDD8-dissociated protein 2; p120 CAND2; TBP-interacting protein 120B; TBP-interacting protein b; TBP-interacting protein of 120 kDa B; TBP-interacting protein Tip120B; Tip120B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	150,507,659 - 150,535,755 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	150,507,657 - 150,541,293 (+)	Ensembl				GRCr8
mRatBN7.2	4	148,835,050 - 148,864,039 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	148,835,053 - 148,863,153 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	155,063,763 - 155,091,880 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	150,847,780 - 150,875,897 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	149,470,682 - 149,498,799 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	147,686,487 - 147,714,593 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	147,686,490 - 147,714,585 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	210,970,266 - 210,998,152 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	151,912,174 - 151,940,734 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	137,725,100 - 137,753,194 (+)	NCBI		Celera
RGSC_v3.1	4	152,157,014 - 152,185,575 (+)	NCBI
Cytogenetic Map	4	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atrial fibrillation (ISO)

Familial Cerebral Cavernous Malformation (ISO)

Postoperative Atrial Fibrillation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acetamide (EXP)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cantharidin (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clobetasol (ISO)

dibutyl phthalate (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

flavonoids (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

ketamine (EXP)

L-methionine (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

protein ubiquitination (IBA)

SCF complex assembly (IBA,IEA)

Cellular Component

cytosol (IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

protein binding (ISO)

TBP-class protein binding (IDA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues.	Aoki T, etal., Biochem Biophys Res Commun 1999 Aug 11;261(3):911-6.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.	Koskimäki J, etal., Acta Neuropathol Commun. 2019 Aug 19;7(1):132. doi: 10.1186/s40478-019-0789-0.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation.	Wang P, etal., Sci Rep. 2018 Feb 19;8(1):3297. doi: 10.1038/s41598-018-21611-7.
10.	NEURL rs6584555 and CAND2 rs4642101 contribute to postoperative atrial fibrillation: a prospective study among Chinese population.	Wei T, etal., Oncotarget. 2016 Jul 5;7(27):42617-42624. doi: 10.18632/oncotarget.9422.

Additional References at PubMed

PMID:12692129	PMID:26316108

Genomics

Comparative Map Data

Cand2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	150,507,659 - 150,535,755 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	150,507,657 - 150,541,293 (+)	Ensembl				GRCr8
mRatBN7.2	4	148,835,050 - 148,864,039 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	148,835,053 - 148,863,153 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	155,063,763 - 155,091,880 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	150,847,780 - 150,875,897 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	149,470,682 - 149,498,799 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	147,686,487 - 147,714,593 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	147,686,490 - 147,714,585 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	210,970,266 - 210,998,152 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	151,912,174 - 151,940,734 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	137,725,100 - 137,753,194 (+)	NCBI		Celera
RGSC_v3.1	4	152,157,014 - 152,185,575 (+)	NCBI
Cytogenetic Map	4	q42	NCBI

CAND2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	12,796,680 - 12,834,803 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	12,796,472 - 12,834,818 (+)	Ensembl			hg38	GRCh38
GRCh37	3	12,838,179 - 12,876,302 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	12,813,171 - 12,851,301 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	3	12,776,461 - 12,814,604 (+)	NCBI		Celera
Cytogenetic Map	3	p25.2	NCBI
HuRef	3	12,772,260 - 12,810,226 (+)	NCBI		HuRef
CHM1_1	3	12,788,141 - 12,826,306 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	12,798,170 - 12,836,312 (+)	NCBI		T2T-CHM13v2.0

Cand2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	115,751,518 - 115,782,516 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	115,751,499 - 115,782,518 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	115,774,557 - 115,805,555 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	115,774,538 - 115,805,557 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	115,724,575 - 115,755,573 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	115,740,194 - 115,770,488 (+)	NCBI		MGSCv36	mm8
Celera	6	117,614,220 - 117,645,199 (+)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	53.71	NCBI

Cand2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	17,891,796 - 17,913,866 (-)	Ensembl
ChiLan1.0	NW_004955429	17,891,306 - 17,913,961 (-)	NCBI	ChiLan1.0	ChiLan1.0

CAND2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	12,781,415 - 12,817,289 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	12,786,216 - 12,822,052 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	12,722,259 - 12,757,983 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	13,066,133 - 13,102,246 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	13,066,135 - 13,102,246 (+)	Ensembl			panPan2	panpan1.1

CAND2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	5,756,576 - 5,789,892 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	5,757,566 - 5,811,408 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	5,793,865 - 5,827,176 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	5,786,186 - 5,819,576 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	5,787,164 - 5,820,601 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	5,502,290 - 5,535,612 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	5,855,197 - 5,888,510 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	5,830,851 - 5,864,169 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cand2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	17,900,816 - 17,922,373 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936602	988,312 - 1,008,781 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936602	987,292 - 1,008,825 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAND2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	68,758,734 - 68,787,192 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	68,758,739 - 68,787,200 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	76,028,327 - 76,057,637 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAND2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	48,771,419 - 48,809,911 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	48,771,987 - 48,809,093 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	117,679,110 - 117,717,259 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cand2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624872	404,495 - 429,322 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624872	404,263 - 429,866 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cand2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	30,908,461 - 30,936,811 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cand2
214 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	468
Count of miRNA genes:	227
Interacting mature miRNAs:	272
Transcripts:	ENSRNOT00000014207, ENSRNOT00000014217
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	146370897	184426481	Rat
2302049	Pia32	Pristane induced arthritis QTL 32	5.1	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	107346299	152346299	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	134095016	179095016	Rat
1582237	Kidm34	Kidney mass QTL 34	4	0.0001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	4	149763204	169799698	Rat
61446	Coreg2	Compensatory renal growth QTL 2	3.5		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	4	150095743	159267220	Rat
1300116	Hrtrt5	Heart rate QTL 5	3.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	117737142	152833657	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	146370897	184426481	Rat
1358364	Sradr4	Stress Responsive Adrenal Weight QTL 4	4.92		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	131384565	176384565	Rat
6478763	Anxrr46	Anxiety related response QTL 46		0.07428	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
6478760	Anxrr45	Anxiety related response QTL 45		0.06717	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
61451	Ciaa4	CIA Autoantibody QTL 4	3.1		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	4	123870974	168870974	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	140059299	181024663	Rat
1331802	Srn5	Serum renin concentration QTL 5	3.045		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	4	117559384	162559384	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
7207480	Bss105	Bone structure and strength QTL 105	8.1		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	4	111383604	156383604	Rat
731165	Uae21	Urinary albumin excretion QTL 21	2.4	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	108206096	153206096	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	106848959	168870974	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	94638356	168870820	Rat
7411558	Bw133	Body weight QTL 133	13.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	127263297	172263297	Rat
6478778	Anxrr51	Anxiety related response QTL 51		0.25384	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	126334185	171334185	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	147299608	184426481	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
631511	Pia7	Pristane induced arthritis QTL 7	4.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
1549832	Bss3	Bone structure and strength QTL 3	11		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	4	111383604	156383604	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82944895	154403548	Rat
634347	Hcar8	Hepatocarcinoma resistance QTL 8	5.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	124700988	169700988	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	100752691	179366077	Rat
1581566	Eae21	Experimental allergic encephalomyelitis QTL 21	6.2		body mass (VT:0001259)	maximum body weight loss to initial body weight ratio (CMO:0001400)	4	137447185	182447185	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	137430611	182430611	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	86709649	168870974	Rat
61422	Cia13	Collagen induced arthritis QTL 13	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	134199006	168870974	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	148121375	176967367	Rat
737978	Pia23	Pristane induced arthritis QTL 23	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
12798519	Anxrr54	Anxiety related response QTL 54	2.54	0.05	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	116184844	161184844	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	57613339	151163960	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
12798525	Anxrr57	Anxiety related response QTL 57	3.21	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	148834094	168870974	Rat

Markers in Region

RH135165

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	148,862,375 - 148,862,560 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	147,713,808 - 147,713,992	NCBI	Rnor6.0
Rnor_5.0	4	210,997,367 - 210,997,551	UniSTS	Rnor5.0
RGSC_v3.4	4	151,939,957 - 151,940,141	UniSTS	RGSC3.4
Celera	4	137,752,417 - 137,752,601	UniSTS
RH 3.4 Map	4	950.81	UniSTS
Cytogenetic Map	4	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	160	91	90	59	85	59	6	348	185	11	139	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_181362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB029324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB029341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB029342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014207 ⟹ ENSRNOP00000014207

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	150,507,657 - 150,536,896 (+)	Ensembl
mRatBN7.2 Ensembl	4	148,835,075 - 148,863,153 (+)	Ensembl
Rnor_6.0 Ensembl	4	147,692,028 - 147,714,585 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000014217 ⟹ ENSRNOP00000014217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	150,507,660 - 150,536,210 (+)	Ensembl
mRatBN7.2 Ensembl	4	148,835,053 - 148,863,153 (+)	Ensembl
Rnor_6.0 Ensembl	4	147,686,490 - 147,714,585 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086660 ⟹ ENSRNOP00000071689

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	147,686,545 - 147,714,039 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134792 ⟹ ENSRNOP00000102500

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	150,507,678 - 150,536,896 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000138286 ⟹ ENSRNOP00000106914

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	150,509,925 - 150,536,896 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000140821 ⟹ ENSRNOP00000108531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	150,507,660 - 150,541,293 (+)	Ensembl

RefSeq Acc Id:

NM_181362 ⟹ NP_852027

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	150,507,660 - 150,535,755 (+)	NCBI
mRatBN7.2	4	148,835,053 - 148,863,153 (+)	NCBI
Rnor_6.0	4	147,686,490 - 147,714,585 (+)	NCBI
Rnor_5.0	4	210,970,266 - 210,998,152 (+)	NCBI
RGSC_v3.4	4	151,912,174 - 151,940,734 (+)	RGD
Celera	4	137,725,100 - 137,753,194 (+)	RGD

Sequence:

show sequence

AGGGGAGGTCGCGCCGCCATATTCGATTCGACCCGCAACCCGCGGCGCAGCCAGCATGAGTACC
GGTGCCTTCTACATCTCCAGCCTGCTGGAGAAGATGACGTCCAGCGACAAAGACTTCAGGTTCA
TGGCTACCAGTGACCTGATGTCAGAGTTGCAGAAAGACTCCATCCAGCTGGATGAGGACAGCGA
GCGTAAGGTGGTGAGGACGCTCCTGCGGCTCCTGGAGGACAGGAGTGGTGAGGTGCAGAACCTG
GCTGTCAAGTGCCTGGGTCCCCTGGTGGGCAAGGTGAAGGAGTACCAAGTGGAGAACATTGTGG
ATACCCTTTGTGCCAACATGCGGTCAGACAAGGAGCAGCTGCGCGACATCGCTGGCATTGGCCT
GAAGACCGTGCTTTCAGAGCTGCCTCCAGCTGCCACAGGCTCAGGGCTGGCTATCAGTGTGTGC
CGCAAGATCACCGGCCAGCTCACCAGTGCCATCGCCCAGCAGGAGGATGTGGCTGTGCAGCTGG
AAGCCCTGGACATCCTCTCCGACATGCTGAGCAGGCTAGGTGCCCCATTGGGCACCTTCCATGC
AAGCCTGCTACACTGCCTATTGCCTCAGCTGAGCAGCCCGCGCCTGGCTGTGCGCAAGCGCACC
GTTGTCGCACTCGGTCATCTGGCAGCCGCCTGCAGCACGGACCTCTTCGTGGAGCTTGCTGACC
ATCTGGTGGACCGGCTGCCTGGGCCACGGGCACCTGCCAGCCCTGCAGCCATTCGAACCCTGAT
CCAGTGCTTGGGCAGCGTGGGCCGGCAGGCAGGCCATCGCCTGGGGGCCCACCTGGACCGCCTG
ATGCCCTTGGTGGAGGAGTTCTGCAACCTGGATGACGATGAGCTGAGAGAGTCCTGCCTCCAGG
CCTTCGAGGCCTTCCTAAGAAAGTGCCCCAAGGAGATGGACCCTCATGTACCCAATGTGACCAG
CCTTTGCCTGCAGTACATGAAGCACGACCCCAACTACAACCATGACAGTGACGAAGAAGAGCAA
ATGGAGACCGAGGACAGTGAATTCAGTGAGCAAGAGAGTGAGGACGAGTACAGTGACGATGACG
ACATGAGCTGGAAGGTCCGCCGAGCTGCGGCCAAGTGCATGGCAGCCCTGATCAGCTCTCGGCC
CGACCTCTTACCCGACTTCCACTGCACGCTGGCACCTGCGCTTATCCGCTGCTTCAAGGAGCGG
GAGGAGAACGTCAAGGCAGACATCTTTGGGGCTTACATCATGTTGCTGCGACATACACGGCCCC
CTAAAGGGTGGCTGGAGGCTGTGGAGGAGCCCACCCAGACGGGCAGAAACCTCAATATGCTACG
AGCGCAGGTGCCCCTAGTGATGAAGGCCCTGCAGCGACAACTTAAAGACCGGAATGTTCGGACC
CGCCAGGGGTGCTTCAACCTCTTTACCGAGCTGGCAGGCGTCCTCCCTGGCTGCCTGGCAGAGC
ACATGACTGTCTTGGTGTCAGGCATTGTCTTTTCACTGGCTGACTACTCCAGCTCCTCCACCAT
ACGGATGGATGCCCTGGCCTTCCTACAGGGCCTTCTGGGTACAGAGCCAGCTGAGGCCTTCCAC
CCACACTTGCCGACCCTCCTACCGCCTGTGATGGCCTGTGTGGCTGACCCTTTCTACAAGGTGG
CAGCTGAGGCCTTATTGGTGCTCCAGGAGCTGGTGCGGACCCTGTGGCCACTGGATAGGCCTCG
GCTGCTGGACCCTGAGCCGTACGTGGGAGAGATGTCCACAGCTACCCTGGCACGACTCCGAGCC
ACTGACCTGGACCAGGAGGTGAAGGAACGGGCCATCTCTTGTGTGGGCCACCTTGTGGGTCACC
TTGGCGACCGGCTTGGGGATGACCTAGAGCCCACACTTCTGCTTCTCCTTGATCGCCTACGGAA
TGAGATAACCCGGTTGCCTGCTGTCAAGGCACTGACACTGGTGGCGGTGTCCCCATTGCGACTT
GATCTGCAGCCCATCCTGGCCGAGGCACTGCCCATCCTCGCTTCATTTCTGCGCAAGAATCAAC
GGGCCCTGCGGCTGGCCACACTGGCCGCCCTGGATGCTCTGGCTCAGAGTCAGGGCCTCGGCCT
GCCCCCGCCTGCTGTTCGGAGTGTGCTAGCTGAGCTGCCTGCTCTGGTCAGTGAGAATGACATG
CATGTGGCCCAGCTGGCTGTTGACTTCCTCACCACGGTGACGCAGACCCAGCCGGCCTCTCTGG
TTGAAGTCAGTGGGCCTGTTCTGGAGGAGCTGCTGCAGCTGCTGCACTCACCCTTGCTGCCTGC
TGGGGTGCTGGCAGCCACTGAAGGCTTCCTGCAGGCGCTGGTGGGGACCCGCCCTCCATGTGTG
GAGTACTCAGAGCTCATTAGCCTGCTCACTGCGCCTGTTTATAACCAGGTTGGGGATGGAGGAC
CCGGCCTGCACAAGCAGGTGTTCCACTCATTGGCTCGGTGTGTGGCTGCCCTCTCAGCTGCCTG
TCCCCAGGAGGCAGCAGGCACTGCCAGCCGCCTGGTGTGTGATGCCAGGTCACCCCACTCAAGC
ACAGGGGTCAAAGTCTTGGCATTCCTATCACTGGCTGAGGTGGGCCAGGTGGCTGGGCCAGGCC
CCCAGAGGGAGCTGAAGACAGTGCTTCTGGAAGCCCTGGGGTCTCCCAGTGAGGACGTGAGGGC
TGCAGCTGCATATGCCCTGGGCCGTGTGGGTGCTGGCAACCTGCCTGACTTCCTGCCCTTCCTG
CTGGCACAAATCGAGGCCCAACCCCGACGACAGTACCTGCTGCTACATGCACTCAGGGAGGCCC
TGGGGGCTGCCCAGCCTGACAACCTGAAGCCCTATGTTGAGGATGTGTGGGCACTGCTCTTCCA
GCGCTGTGAGAGCCCTGAGGAAGGCACTCGGTGTGTGGTGGCTGAATGCATCGGAAAGCTAGTG
TTTGTGAACCCTCCCTTCCTCCTGCCCCGATTCCGGAAGCAGCTTGCTGCAGGTCAGCCATACA
CGCGGAGCACAGTGATCACTGCAGTCAAGTTCCTCATCTCAGACCAGCCACACTCCATCGACCC
TCTCCTGAAGAGCTTCATTGCAGAGTTCATGGAAAGCCTGCAGGACCCAGACCTGAACGTGCGC
CGGGCCACACTCACCTTCTTCAACTCAGCTGTGCACAACAAACCGTCGCTGGTCCGGGACCTGT
TGGATGACATCCTACCCCTCCTCTACCAGGAGACCAAGATCCGCCGGGACCTCATCCGAGAGGT
GGAGATGGGGCCCTTCAAGCATACTGTAGATGATGGGCTGGATGTGAGGAAGGCTGCCTTCGAG
TGCATGTACTCGCTACTGGAGAGCTGCCTGGGCCAGCTGGACATCTGCGAGTTTCTGAACCACG
TGGAGGATGGGCTAAAGGACCATTATGACATCCGGATGCTGACCTTCATCATGCTGGCCCGGCT
GGCCGCTCTTTGCCCTGCACCTGTCCTGCAGAGGGTGGACCGGCTCATCGAGCCACTCAGAGCC
ACCTGTACTGCCAAGGTCAAAGCTGGTTCTGTGAAGCAGGAGCTGGAGAAGCAGGATGAGCTGA
AGCGCTCAGCAATGCGGGCAGTGGCTGCCCTGATGACTAACCCTGAGGTGCGGAAGAGCCCCAG
TGTGGCTGACTTTTCTACCCAGATCCGATCCAACCCAGAACTCGCCACCCTCTTTGAGAGCATC
CAAAAGGACACAGCCTCTGGCCCCAGCATGGACTCTATGGAACTTAGCTAGCTGTCCCCAATAC
AAGCCTCCCTTCTCATCCCTATTGGCCTTGGCCTCTCCTGTCCTTCCTAGTCAGCCTCAGTGCC
TTTGCTAGGGTCCCCTGCTCACAGCCCGTGTCAAAGCTGGGCCCATTAACTCAGGACATTCATG
AGGGTGATGTCCCACCACCTTTACACTGCACCCCTCCACTCACTTAAAAGCCAGCATTGATTGC
CCTGTGCATAAGACCGGAAGACAAGCAGGGGGTTGACTTCCTACTTCACTTGCTCTGGCCTCCA
AATGTCAATTAGCACCCTGGGCCTGGCCATGGGTAGGGTATGTAGAACCCATGCAAGCTCTAGG
TCTTGGCACAAGAGAACCAATTTATACTGAATGCCTCACTAATTAGAGTAAAAACTGTTTACAG
GGAAGATGGTATGGATCATTGGACTGTCCACTGTTTTAAACATCCCTATTCTCATGGCCCAGGC
ATGTAACAGTGTTGGTTTGTGCTCTTCCCATGTGTGTAGTTGTTAGTACTGAAAATTTAAGTAT
AAATAACAGTCCAGGGTTTAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006237004 ⟹ XP_006237066

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	150,507,659 - 150,535,612 (+)	NCBI
mRatBN7.2	4	148,835,050 - 148,864,039 (+)	NCBI
Rnor_6.0	4	147,686,487 - 147,714,593 (+)	NCBI
Rnor_5.0	4	210,970,266 - 210,998,152 (+)	NCBI

Sequence:

show sequence

GGGAGGGGAGGTCGCGCCGCCATATTCGATTCGACCCGCAACTCGCGGCGCAGCCAGCATGAGT
ACCGGTGCCTTCTACATCTCCAGCCTGCTGGAGAAGATGACGTCCAGCGACAAAGACTTCAGCC
CCAAGTCCCTTGGTGGTAGTAGGGTTTTGGATCCTTTGCCCTGGCTTCAGATCTTGGCAGCCAT
CACTGACTGGATCTCTGGGGACCGAACCCAGGACCTTGCGCTTCCTAGGTTCATGGCTACCAGT
GACCTGATGTCAGAGTTGCAGAAAGACTCCATCCAGCTGGATGAGGACAGCGAGCGTAAGGTGG
TGAGGACGCTCCTGCGGCTCCTGGAGGACAGGAGTGGTGAGGTGCAGAACCTGGCTGTCAAGTG
CCTGGGTCCCCTGGTGGGCAAGGTGAAGGAGTACCAAGTGGAGAACATTGTGGATACCCTTTGT
GCCAACATGCGGTCAGACAAGGAGCAGCTGCGCGACATCGCTGGCATTGGCCTGAAGACCGTGC
TTTCAGAGCTGCCTCCAGCTGCCACAGGCTCGGGGCTGGCTATCAGTGTGTGCCGCAAGATCAC
CGGCCAGCTCACCAGTGCCATCGCCCAGCAGGAGGATGTGGCTGTGCAGCTGGAAGCCCTGGAC
ATCCTCTCCGACATGCTGAGCAGGCTAGGTGCCCCATTGGGCACCTTCCATGCAAGCCTGCTAC
ACTGCCTATTGCCTCAGCTGAGCAGCCCGCGCCTGGCTGTGCGCAAGCGCACCGTTGTCGCACT
CGGTCATCTGGCAGCCGCCTGCAGCACGGACCTCTTCGTGGAGCTTGCTGATCATCTGGTGGAC
CGGCTGCCTGGGCCACGGGCACCTGCCAGCCCTGCAGCCATTCGAACCCTGATCCAGTGCTTGG
GCAGCGTGGGCCGGCAGGCAGGCCATCGCCTGGGGGCCCACCTGGACCGCCTGATGCCCTTGGT
GGAGGAGTTCTGCAACCTGGATGACGATGAGCTGAGAGAGTCCTGCCTCCAGGCCTTCGAGGCC
TTCCTAAGAAAGTGCCCCAAGGAGATGGACCCTCATGTACCCAATGTGACCAGCCTTTGCCTGC
AGTACATGAAGCACGACCCCAACTACAACCATGACAGTGACGAAGAAGAGCAAATGGAGACCGA
GGACAGTGAATTCAGTGAGCAAGAGAGTGAGGACGAGTACAGTGACGATGACGACATGAGCTGG
AAGGTCCGCCGAGCTGCGGCCAAGTGCATGGCAGCCCTGATCAGCTCTCGGCCCGACCTCTTAC
CCGACTTCCACTGCACGCTGGCACCTGCGCTTATCCGCCGCTTCAAGGAGCGGGAGGAGAACGT
CAAGGCAGACATCTTTGGGGCTTACATCATGTTGCTGCGACATACACGGCCCCCTAAAGGGTGG
CTGGAGGCTGTGGAGGAGCCCACCCAGACTGGCAGAAACCTCAATATGCTACGAGCGCAGGTGC
CCCTAGTGATGAAGGCCCTGCAGCGACAACTTAAAGACCGGAATGTTCGGACCCGCCAGGGGTG
CTTCAACCTCTTTACCGAGCTGGCAGGCGTCCTCCCTGGCTGCCTGGCAGAGCACATGACTGTC
TTGGTGTCAGGCATTGTCTTTTCACTGGCTGACTACTCCAGCTCCTCCACCATACGGATGGATG
CCCTGGCCTTCCTACAGGGCCTTCTGGGTACAGAGCCAGCTGAGGCCTTCCACCCACACTTGCC
GACCCTCCTACCGCCTGTGATGGCCTGTGTGGCTGACCCTTTCTACAAGGTGGCAGCTGAGGCC
TTATTGGTGCTCCAGGAGCTGGTGCGGACCCTGTGGCCACTGGATAGGCCTCGGCTGCTGGACC
CTGAGCCGTACGTGGGAGAGATGTCCACAGCTACCCTGGCACGACTCCGAGCCACTGACCTGGA
CCAGGAGGTGAAGGAACGGGCCATCTCTTGTGTGGGCCACCTTGTGGGTCACCTTGGCGACCGG
CTTGGGGATGACCTAGAGCCCACACTTCTGCTTCTCCTTGATCGCCTACGGAATGAGATAACCC
GGTTGCCTGCTGTCAAGGCACTGACACTGGTGGCGGTGTCCCCATTGCGACTTGATCTGCAGCC
CATCCTGGCCGAGGCACTGCCCATCCTCGCTTCATTTCTGCGCAAGAATCAACGGGCCCTGCGG
CTGGCCACACTGGCCGCCCTGGATGCTCTGGCTCAGAGTCAGGGCCTCGGCCTGCCCCCGCCTG
CTGTTCGGAGTGTGCTAGCTGAGCTGCCTGCTCTGGTCAGTGAGAATGACATGCATGTGGCCCA
GCTGGCTGTTGACTTCCTCACCACGGTGACGCAGACCCAGCCGGCCTCTCTGGTTGAAGTCAGT
GGGCCTGTTCTGGAGGAGCTGCTGCAGCTGCTGCACTCACCCTTGCTGCCTGCTGGGGTGCTGG
CAGCCACTGAAGGCTTCCTGCAGGCGCTGGTGGGGACCCGCCCTCCATGTGTGGAGTACTCAGA
GCTCATTAGCCTGCTCACTGCACCTGTTTATAACCAGGTTGGGGATGGAGGACCCGGCCTGCAC
AAGCAGGTGTTCCACTCATTGGCTCGGTGTGTGGCTGCCCTCTCAGCTGCCTGTCCCCAGGAGG
CAGCAGGCACTGCCAGCCGCCTGGTGTGTGATGCCAGGTCACCCCACTCAAGCACAGGGGTCAA
AGTCTTGGCATTCCTATCACTGGCTGAGGTGGGCCAGGTGGCTGGGCCAGGCCCCCAGAGGGAG
CTGAAGACAGTGCTTCTGGAAGCCCTGGGGTCTCCCAGTGAGGACGTGAGGGCTGCAGCTGCAT
ATGCCCTGGGCCGTGTGGGTGCTGGCAACCTGCCTGACTTCCTGCCCTTCCTGCTGGCACAAAT
CGAGGCCCAACCCCGACGACAGTACCTGCTGCTACATGCACTCAGGGAGGCCCTGGGGGCTGCC
CAGCCTGACAACCTGAAGCCCTATGTTGAGGATGTGTGGGCACTGCTCTTCCAGCGCTGTGAGA
GCCCTGAGGAAGGCACTCGGTGTGTGGTGGCTGAATGCATCGGAAAGCTAGTGTTTGTGAACCC
TCCCTTCCTCCTGCCCCGATTCCGGAAGCAGCTTGCTGCAGGTCAGCCATACACGCGGAGCACA
GTGATCACTGCAGTCAAGTTCCTCATCTCAGACCAGCCACACTCCATCGACCCTCTCCTGAAGA
GCTTCATTGCAGAGTTCATGGAAAGCCTGCAGGACCCAGACCTGAACGTGCGCCGGGCCACACT
CACCTTCTTCAACTCAGCTGTGCACAACAAACCGTCGCTGGTCCGGGACCTGTTGGATGACATC
CTACCCCTCCTCTACCAGGAGACCAAGATCCGCCGGGACCTCATCCGAGAGGTAGAGATGGGGC
CCTTCAAGCATACTGTAGATGATGGGCTGGATGTGAGGAAGGCTGCCTTCGAGTGCATGTACTC
GCTACTGGAGAGCTGCCTGGGCCAGCTGGACATCTGCGAGTTTCTGAACCACGTGGAGGATGGG
CTAAAGGACCATTATGACATCCGGATGCTGACCTTCATCATGCTGGCCCGGCTGGCCGCTCTTT
GCCCTGCACCTGTCCTGCAGAGGGTGGACCGGCTCATCGAGCCACTCAGAGCCACCTGTACTGC
CAAGGTCAAAGCTGGTTCTGTGAAGCAGGAGCTGGAGAAGCAGGATGAGCTGAAGCGCTCAGCA
ATGCGGGCAGTGGCTGCCCTGATGACTAACCCTGAGGTGCGGAAGAGCCCCAGTGTGGCTGACT
TTTCTACCCAGATCCGATCCAACCCAGAACTCGCCACCCTCTTTGAGAGCATCCAAAAGGACAC
AGCCTCTGGCCCCAGCATGGACTCTATGGAACTTAGCTAGCTGTCCCCAATACAAGCCTCCCTT
CTCATCCCTATTGGCCTTGGCCTCTCCTGTCCTTCCTAGTCAGCCTCAGTGCCTTTGCTAGGGT
CCCCTGCTCACAGCCCCAGTGTCAAAGCTGGGCCCATTAACTCAGGACATTCATGAGGGTGATG
TCCCACCACCTTTACACTGCACCCCTCCACTCACTTAAAAGCCAGCATTGATTGCCCTGTGCAT
AAGACCGGAAGACAAGCAGGGGGTTGACTTCCTACTTCACTTGCTCTGGCCTCCAAATGTCAAT
TAGCACCCTGGGCCTGGCCATGGGTAGGGTATGTAGAACCCATGCAAGCTCTAGGTCTTGGCAC
AAGAGAACCAATTTATACTGAATGCCTCACTAATTAGAGTAAAAACTGTTTACAGGGAAGATGG
TATGGATCATTGGACTGTCCACTGTTTTAAACATCCCTATTCTCATGGCCCAGGCATGTAACAG
TGTTGGTTTGTGCTCTTCCCATGTGTGTAGTTGTTAGTACTGAAAATTTAAGTATAAATAACAG
TCCAGGGTTTCGATTTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_852027	(Get FASTA)	NCBI Sequence Viewer
	XP_006237066	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA83619	(Get FASTA)	NCBI Sequence Viewer
	BAA83620	(Get FASTA)	NCBI Sequence Viewer
	BAA83621	(Get FASTA)	NCBI Sequence Viewer
	EDM02143	(Get FASTA)	NCBI Sequence Viewer
	EDM02144	(Get FASTA)	NCBI Sequence Viewer
	EDM02145	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014207
	ENSRNOP00000102500
GenBank Protein	Q9R0L4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_852027 ⟸ NM_181362

- UniProtKB:

D4AAI5 (UniProtKB/TrEMBL), A6IKZ4 (UniProtKB/TrEMBL), A6IKZ6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSTGAFYISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVRTLLRLLEDRSGEV
QNLAVKCLGPLVGKVKEYQVENIVDTLCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLAI
SVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGTFHASLLHCLLPQLSSPRLAVR
KRTVVALGHLAAACSTDLFVELADHLVDRLPGPRAPASPAAIRTLIQCLGSVGRQAGHRLGAHL
DRLMPLVEEFCNLDDDELRESCLQAFEAFLRKCPKEMDPHVPNVTSLCLQYMKHDPNYNHDSDE
EEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCMAALISSRPDLLPDFHCTLAPALIRCF
KEREENVKADIFGAYIMLLRHTRPPKGWLEAVEEPTQTGRNLNMLRAQVPLVMKALQRQLKDRN
VRTRQGCFNLFTELAGVLPGCLAEHMTVLVSGIVFSLADYSSSSTIRMDALAFLQGLLGTEPAE
AFHPHLPTLLPPVMACVADPFYKVAAEALLVLQELVRTLWPLDRPRLLDPEPYVGEMSTATLAR
LRATDLDQEVKERAISCVGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAVKALTLVAVSP
LRLDLQPILAEALPILASFLRKNQRALRLATLAALDALAQSQGLGLPPPAVRSVLAELPALVSE
NDMHVAQLAVDFLTTVTQTQPASLVEVSGPVLEELLQLLHSPLLPAGVLAATEGFLQALVGTRP
PCVEYSELISLLTAPVYNQVGDGGPGLHKQVFHSLARCVAALSAACPQEAAGTASRLVCDARSP
HSSTGVKVLAFLSLAEVGQVAGPGPQRELKTVLLEALGSPSEDVRAAAAYALGRVGAGNLPDFL
PFLLAQIEAQPRRQYLLLHALREALGAAQPDNLKPYVEDVWALLFQRCESPEEGTRCVVAECIG
KLVFVNPPFLLPRFRKQLAAGQPYTRSTVITAVKFLISDQPHSIDPLLKSFIAEFMESLQDPDL
NVRRATLTFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKA
AFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMLARLAALCPAPVLQRVDRLIEP
LRATCTAKVKAGSVKQELEKQDELKRSAMRAVAALMTNPEVRKSPSVADFSTQIRSNPELATLF
ESIQKDTASGPSMDSMELS

hide sequence

RefSeq Acc Id:	XP_006237066 ⟸ XM_006237004
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0L5 (UniProtKB/Swiss-Prot), Q9R0L4 (UniProtKB/Swiss-Prot), Q9R0L3 (UniProtKB/Swiss-Prot), A0A0G2K139 (UniProtKB/TrEMBL), A6IKZ5 (UniProtKB/TrEMBL), G3V7E8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSTGAFYISSLLEKMTSSDKDFSPKSLGGSRVLDPLPWLQILAAITDWISGDRTQDLALPRFMA TSDLMSELQKDSIQLDEDSERKVVRTLLRLLEDRSGEVQNLAVKCLGPLVGKVKEYQVENIVDT LCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLAISVCRKITGQLTSAIAQQEDVAVQLEA LDILSDMLSRLGAPLGTFHASLLHCLLPQLSSPRLAVRKRTVVALGHLAAACSTDLFVELADHL VDRLPGPRAPASPAAIRTLIQCLGSVGRQAGHRLGAHLDRLMPLVEEFCNLDDDELRESCLQAF EAFLRKCPKEMDPHVPNVTSLCLQYMKHDPNYNHDSDEEEQMETEDSEFSEQESEDEYSDDDDM SWKVRRAAAKCMAALISSRPDLLPDFHCTLAPALIRRFKEREENVKADIFGAYIMLLRHTRPPK GWLEAVEEPTQTGRNLNMLRAQVPLVMKALQRQLKDRNVRTRQGCFNLFTELAGVLPGCLAEHM TVLVSGIVFSLADYSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPTLLPPVMACVADPFYKVAA EALLVLQELVRTLWPLDRPRLLDPEPYVGEMSTATLARLRATDLDQEVKERAISCVGHLVGHLG DRLGDDLEPTLLLLLDRLRNEITRLPAVKALTLVAVSPLRLDLQPILAEALPILASFLRKNQRA LRLATLAALDALAQSQGLGLPPPAVRSVLAELPALVSENDMHVAQLAVDFLTTVTQTQPASLVE VSGPVLEELLQLLHSPLLPAGVLAATEGFLQALVGTRPPCVEYSELISLLTAPVYNQVGDGGPG LHKQVFHSLARCVAALSAACPQEAAGTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGPQ RELKTVLLEALGSPSEDVRAAAAYALGRVGAGNLPDFLPFLLAQIEAQPRRQYLLLHALREALG AAQPDNLKPYVEDVWALLFQRCESPEEGTRCVVAECIGKLVFVNPPFLLPRFRKQLAAGQPYTR STVITAVKFLISDQPHSIDPLLKSFIAEFMESLQDPDLNVRRATLTFFNSAVHNKPSLVRDLLD DILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVE DGLKDHYDIRMLTFIMLARLAALCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQELEKQDELKR SAMRAVAALMTNPEVRKSPSVADFSTQIRSNPELATLFESIQKDTASGPSMDSMELS hide sequence

Ensembl Acc Id:

ENSRNOP00000014217 ⟸ ENSRNOT00000014217

Ensembl Acc Id:

ENSRNOP00000014207 ⟸ ENSRNOT00000014207

Ensembl Acc Id:

ENSRNOP00000071689 ⟸ ENSRNOT00000086660

Ensembl Acc Id:

ENSRNOP00000102500 ⟸ ENSRNOT00000134792

Ensembl Acc Id:

ENSRNOP00000108531 ⟸ ENSRNOT00000140821

Ensembl Acc Id:

ENSRNOP00000106914 ⟸ ENSRNOT00000138286

Protein Domains

TATA-binding protein interacting (TIP20)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R0L4-F1-model_v2	AlphaFold	Q9R0L4	1-1273	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693325

Promoter ID:

EPDNEW_R3850

Type:

multiple initiation site

Name:

Cand2_1

Description:

cullin-associated and neddylation-dissociated 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	147,686,508 - 147,686,568	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620480	AgrOrtholog
BioCyc Gene	G2FUF-43315	BioCyc
Ensembl Genes	ENSRNOG00000010473	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000014207	ENTREZGENE
	ENSRNOT00000134792	ENTREZGENE
Gene3D-CATH	1.25.10.10	UniProtKB/Swiss-Prot
InterPro	ARM-like	UniProtKB/Swiss-Prot
	ARM-type_fold	UniProtKB/Swiss-Prot
	CAND1/CAND2	UniProtKB/Swiss-Prot
	HEAT	UniProtKB/Swiss-Prot
	TATA-bd_TIP120	UniProtKB/Swiss-Prot
KEGG Report	rno:192226	UniProtKB/Swiss-Prot
NCBI Gene	192226	ENTREZGENE
PANTHER	PTHR12696	UniProtKB/Swiss-Prot
Pfam	HEAT	UniProtKB/Swiss-Prot
	TIP120	UniProtKB/Swiss-Prot
PhenoGen	Cand2	PhenoGen
RatGTEx	ENSRNOG00000010473	RatGTEx
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot
UniProt	A0A0G2K139	ENTREZGENE
	A0ABK0LCW9_RAT	UniProtKB/TrEMBL
	A0ABK0LSD5_RAT	UniProtKB/TrEMBL
	A0ABK0LUE2_RAT	UniProtKB/TrEMBL
	A6IKZ4	ENTREZGENE, UniProtKB/TrEMBL
	A6IKZ5	ENTREZGENE, UniProtKB/TrEMBL
	A6IKZ6	ENTREZGENE, UniProtKB/TrEMBL
	CAND2_RAT	UniProtKB/Swiss-Prot
	D4AAI5	ENTREZGENE, UniProtKB/TrEMBL
	G3V7E8	ENTREZGENE, UniProtKB/TrEMBL
	Q9R0L3	ENTREZGENE
	Q9R0L4	ENTREZGENE
	Q9R0L5	ENTREZGENE
UniProt Secondary	Q9R0L3	UniProtKB/Swiss-Prot
	Q9R0L5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Cand2	cullin-associated and neddylation-dissociated 2 (putative)	Tip120B	TBP-interacting protein 120B	Symbol and Name updated	1299863	APPROVED
2005-07-08	Tip120B	TBP-interacting protein 120B		TBP-interacting protein Tip120B	Name updated	1299863	APPROVED
2002-08-07	Tip120B	TBP-interacting protein Tip120B			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to the nucleus	634488
gene_homology	60% identical to the original TIP120A	634488

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD