Cand1 (cullin-associated and neddylation-dissociated 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Cand1 (cullin-associated and neddylation-dissociated 1) Rattus norvegicus
Analyze
Symbol: Cand1
Name: cullin-associated and neddylation-dissociated 1
RGD ID: 620479
Description: Enables TBP-class protein binding activity. Involved in positive regulation of RNA polymerase II transcription preinitiation complex assembly. Predicted to be located in cytoplasm. Predicted to be part of cullin-RING ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human CAND1 (cullin associated and neddylation dissociated 1); PARTICIPATES IN neddylation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cullin associated and neddylation disassociated 1; cullin-associated and neddylation-dissociated protein 1; cullin-associated NEDD8-dissociated protein 1; p120 CAND1; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TBP-interacting protein TIP120A; Tip120; Tip120A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8756,566,765 - 56,604,653 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl756,551,394 - 56,604,655 (-)EnsemblGRCr8
mRatBN7.2754,681,114 - 54,719,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx756,587,617 - 56,625,505 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0758,790,753 - 58,828,639 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0758,568,597 - 58,606,483 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0762,124,362 - 62,162,451 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)Ensemblrn6Rnor6.0
Rnor_5.0762,113,404 - 62,151,493 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4758,461,205 - 58,499,092 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera751,445,526 - 51,483,413 (-)NCBICelera
RGSC_v3.1758,481,934 - 58,519,822 (-)NCBI
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
actinomycin D  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (EXP)
cobalt dichloride  (ISO)
crocidolite asbestos  (ISO)
diazinon  (EXP)
dicrotophos  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
succimer  (ISO)
tert-butyl hydroperoxide  (ISO)
theophylline  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
zinc protoporphyrin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cullin-RING ubiquitin ligase complex  (IEA,ISO,ISS)
cytoplasm  (IEA,ISO,ISS)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)
ubiquitin ligase complex  (IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism. Makino Y, etal., Mol Cell Biol. 1999 Dec;19(12):7951-60.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Parry G and Estelle M, Semin Cell Dev Biol. 2004 Apr;15(2):221-9.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Molecular cloning of a novel 120-kDa TBP-interacting protein. Yogosawa S, etal., Biochem Biophys Res Commun 1996 Dec 13;229(2):612-7.
9. Induced expression, localization, and chromosome mapping of a gene for the TBP-interacting protein 120A. Yogosawa S, etal., Biochem Biophys Res Commun 1999 Dec 9;266(1):123-8.
Additional References at PubMed
PMID:10441524   PMID:10526239   PMID:12609982   PMID:15537541   PMID:19056867   PMID:19946888   PMID:20458337   PMID:21249194   PMID:21630459   PMID:22405651   PMID:23533145   PMID:26316108  
PMID:28131823   PMID:29367474   PMID:29476059   PMID:32357304   PMID:34974108   PMID:38095165  


Genomics

Comparative Map Data
Cand1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8756,566,765 - 56,604,653 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl756,551,394 - 56,604,655 (-)EnsemblGRCr8
mRatBN7.2754,681,114 - 54,719,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx756,587,617 - 56,625,505 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0758,790,753 - 58,828,639 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0758,568,597 - 58,606,483 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0762,124,362 - 62,162,451 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)Ensemblrn6Rnor6.0
Rnor_5.0762,113,404 - 62,151,493 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4758,461,205 - 58,499,092 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera751,445,526 - 51,483,413 (-)NCBICelera
RGSC_v3.1758,481,934 - 58,519,822 (-)NCBI
Cytogenetic Map7q22NCBI
CAND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381267,269,358 - 67,319,953 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1267,269,358 - 67,319,953 (+)Ensemblhg38GRCh38
GRCh371267,663,138 - 67,713,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361265,949,416 - 65,994,189 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341265,949,415 - 65,994,187NCBI
Celera1267,327,070 - 67,372,407 (+)NCBICelera
Cytogenetic Map12q14.3-q15NCBI
HuRef1264,713,845 - 64,759,496 (+)NCBIHuRef
CHM1_11267,630,340 - 67,675,666 (+)NCBICHM1_1
T2T-CHM13v2.01267,248,745 - 67,299,478 (+)NCBIT2T-CHM13v2.0
Cand1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910119,034,717 - 119,075,960 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10119,035,160 - 119,075,960 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3810119,198,812 - 119,240,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10119,199,255 - 119,240,055 (-)Ensemblmm10GRCm38
MGSCv3710118,635,868 - 118,677,111 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610118,601,872 - 118,724,036 (-)NCBIMGSCv36mm8
Celera10121,557,633 - 121,598,810 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1067.08NCBI
Cand1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545813,815,819 - 13,850,007 (+)Ensembl
ChiLan1.0NW_00495545813,815,819 - 13,850,007 (+)NCBIChiLan1.0ChiLan1.0
CAND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21027,037,080 - 27,084,905 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11227,033,844 - 27,080,879 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,592,833 - 21,638,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,099,962 - 22,145,013 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,099,962 - 22,145,013 (-)EnsemblpanPan2panpan1.1
CAND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1109,652,176 - 9,683,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl109,641,732 - 9,680,118 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha109,571,760 - 9,612,014 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0109,755,181 - 9,795,481 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl109,755,061 - 9,794,999 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1109,631,961 - 9,672,240 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0109,877,617 - 9,917,882 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0109,999,578 - 10,039,865 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cand1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494548,854,528 - 48,892,090 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365455,218,407 - 5,255,245 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365455,217,947 - 5,255,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl531,657,501 - 31,700,163 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1531,657,508 - 31,700,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2534,955,840 - 34,994,724 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11162,923,198 - 62,968,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1162,922,885 - 62,966,994 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037182,746,329 - 182,791,692 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cand1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248021,014,515 - 1,049,561 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248021,010,749 - 1,049,253 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cand1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11197,155,348 - 197,196,957 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cand1
168 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:38
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000010720
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)74968283263890004Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74299622658678836Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
AI195005  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8756,567,009 - 56,567,131 (+)Marker Load Pipeline
mRatBN7.2754,681,357 - 54,681,480 (+)MAPPERmRatBN7.2
Rnor_6.0762,124,606 - 62,124,728NCBIRnor6.0
Rnor_5.0762,113,648 - 62,113,770UniSTSRnor5.0
RGSC_v3.4758,461,449 - 58,461,571UniSTSRGSC3.4
Celera751,445,770 - 51,445,892UniSTS
Cytogenetic Map7q22UniSTS
RH138241  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,719,336 - 54,719,472 (+)MAPPERmRatBN7.2
Rnor_6.0762,162,786 - 62,162,921NCBIRnor6.0
Rnor_5.0762,151,828 - 62,151,963UniSTSRnor5.0
RGSC_v3.4758,499,427 - 58,499,562UniSTSRGSC3.4
Celera751,483,748 - 51,483,883UniSTS
RH 3.4 Map7489.3UniSTS
Cytogenetic Map7q22UniSTS
RH139433  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,680,931 - 54,681,056 (+)MAPPERmRatBN7.2
Rnor_6.0762,124,180 - 62,124,304NCBIRnor6.0
Rnor_5.0762,113,222 - 62,113,346UniSTSRnor5.0
RGSC_v3.4758,461,023 - 58,461,147UniSTSRGSC3.4
Celera751,445,344 - 51,445,468UniSTS
RH 3.4 Map7489.3UniSTS
Cytogenetic Map7q22UniSTS
BI275731  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,681,369 - 54,681,548 (+)MAPPERmRatBN7.2
Rnor_6.0762,124,618 - 62,124,796NCBIRnor6.0
Rnor_5.0762,113,660 - 62,113,838UniSTSRnor5.0
RGSC_v3.4758,461,461 - 58,461,639UniSTSRGSC3.4
Celera751,445,782 - 51,445,960UniSTS
RH 3.4 Map7488.0UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010720   ⟹   ENSRNOP00000010720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl756,566,765 - 56,604,655 (-)Ensembl
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)Ensembl
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111987   ⟹   ENSRNOP00000086186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl756,551,394 - 56,604,655 (-)Ensembl
mRatBN7.2 Ensembl754,680,900 - 54,698,264 (-)Ensembl
RefSeq Acc Id: NM_054004   ⟹   NP_446456
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8756,566,765 - 56,604,653 (-)NCBI
mRatBN7.2754,681,114 - 54,719,002 (-)NCBI
Rnor_6.0762,124,362 - 62,162,451 (-)NCBI
Rnor_5.0762,113,404 - 62,151,493 (-)NCBI
RGSC_v3.4758,461,205 - 58,499,092 (-)RGD
Celera751,445,526 - 51,483,413 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446456 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA13432 (Get FASTA)   NCBI Sequence Viewer  
  EDM16585 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010720
  ENSRNOP00000010720.3
GenBank Protein P97536 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446456   ⟸   NM_054004
- UniProtKB: P97536 (UniProtKB/Swiss-Prot),   A6IGW3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010720   ⟸   ENSRNOT00000010720
Ensembl Acc Id: ENSRNOP00000086186   ⟸   ENSRNOT00000111987
Protein Domains
TATA-binding protein interacting (TIP20)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97536-F1-model_v2 AlphaFold P97536 1-1230 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695221
Promoter ID:EPDNEW_R5746
Type:initiation region
Name:Cand1_1
Description:cullin-associated and neddylation-dissociated 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0762,162,447 - 62,162,507EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620479 AgrOrtholog
BioCyc Gene G2FUF-33932 BioCyc
Ensembl Genes ENSRNOG00000007834 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010720 ENTREZGENE
  ENSRNOT00000010720.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot
  CAND1/CAND2 UniProtKB/Swiss-Prot
  TATA-bd_TIP120 UniProtKB/Swiss-Prot
KEGG Report rno:117152 UniProtKB/Swiss-Prot
NCBI Gene 117152 ENTREZGENE
PANTHER PTHR12696 UniProtKB/Swiss-Prot
Pfam HEAT_EZ UniProtKB/Swiss-Prot
  TIP120 UniProtKB/Swiss-Prot
PhenoGen Cand1 PhenoGen
RatGTEx ENSRNOG00000007834 RatGTEx
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot
UniProt A0A8I6A6C9_RAT UniProtKB/TrEMBL
  A6IGW3 ENTREZGENE, UniProtKB/TrEMBL
  CAND1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cand1  cullin-associated and neddylation-dissociated 1  Cand1  cullin associated and neddylation disassociated 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Cand1  cullin associated and neddylation disassociated 1  Tip120A  TBP-interacting protein 120A  Symbol and Name updated 1299863 APPROVED
2005-07-08 Tip120A  TBP-interacting protein 120A      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tip120A  TBP-interacting protein 120A      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the nucleus 634479
gene_protein 120-kD protein 634479