Cyp2c7 (cytochrome P450, family 2, subfamily c, polypeptide 7) - Rat Genome Database

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Gene: Cyp2c7 (cytochrome P450, family 2, subfamily c, polypeptide 7) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cyp2c7 (Ensembl: LOC134483996)
Name: cytochrome P450, family 2, subfamily c, polypeptide 7 (Ensembl:cytochrome P450 2C7-like)
RGD ID: 620379
Description: Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including response to lipopolysaccharide; response to retinoic acid; and response to tetrachloromethane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Orthologous to human CYP2C8 (cytochrome P450 family 2 subfamily C member 8); PARTICIPATES IN arachidonic acid metabolic pathway; linoleic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Cyp2c39; CYPIIC7; cytochrome P450 2C7; cytochrome P450 2C7-like; cytochrome P450, 2c39; cytochrome P450F; LOC100361347; LOC100911552; LOC100911791; LOC103691183; MGC156667; P450F; PTF1; uncharacterized LOC103691183
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,966,295 - 248,022,393 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1247,966,346 - 248,022,388 (+)EnsemblGRCr8
mRatBN7.21237,332,641 - 237,388,714 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1237,332,659 - 237,388,709 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1245,750,823 - 245,806,851 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01252,856,984 - 252,912,966 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01245,510,012 - 245,565,966 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01147,422,999 - 148,119,979 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1148,053,687 - 148,119,857 (-)Ensemblrn6Rnor6.0
Rnor_5.01154,329,783 - 154,407,698 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.11244,044,956 - 244,719,024 (+)NCBI
Cytogenetic Map1q53NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Neonatal phenobarbital imprints overexpression of cytochromes P450 with associated increase in tumorigenesis and reduced life span. Agrawal AK and Shapiro BH, FASEB J. 2005 Mar;19(3):470-2. Epub 2005 Jan 5.
2. Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf. Borlakoglu JT, etal., Biochem Pharmacol. 1993 Apr 6;45(7):1373-86.
3. PPARalpha activators down-regulate CYP2C7, a retinoic acid and testosterone hydroxylase. Fan LQ, etal., Toxicology. 2004 Oct 15;203(1-3):41-8.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA. Gonzalez FJ, etal., J Biol Chem 1986 Aug 15;261(23):10667-72.
6. Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats. Hakkak R, etal., Biochem Pharmacol. 1996 Jan 12;51(1):61-9.
7. Sexual differentiation and regulation of cytochrome P-450 CYP2C7. Henderson CJ, etal., Biochim Biophys Acta. 1992 Jan 9;1118(2):99-106.
8. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
9. Complementary DNA cloning of cytochrome P-450s related to P-450(M-1) from the complementary DNA library of female rat livers. Predicted primary structures for P-450f, PB-1, and PB-1-related protein with a bizarre replacement block and their mode of transcriptional expression. Kimura H, etal., J Biol Chem 1988 Jan 15;263(2):701-7.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axis. Morgan ET Biochem Pharmacol. 1993 Jan 26;45(2):415-9.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Growth hormone-regulated periportal expression of CYP2C7 in rat liver. Oinonen T, etal., Biochem Pharmacol. 2000 Mar 1;59(5):583-9.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. GOA pipeline RGD automated data pipeline
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Comprehensive gene review and curation RGD comprehensive gene curation
19. CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids. Westin S, etal., Mol Cell Endocrinol. 1997 May 16;129(2):169-79.
Additional References at PubMed
PMID:2385231   PMID:3308889   PMID:3801454   PMID:12477932   PMID:15047867   PMID:21940400  


Genomics

Variants

.
Variants in Cyp2c7
706 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:94
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000040325
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1578775Iddm21Insulin dependent diabetes mellitus QTL 214.13blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1245782829270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1247133834270518180Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1237995023269633915Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1234540191270518180Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1238398865255849249Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1233204160270518180Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1241569529269633915Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1243953669270518180Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat

Markers in Region
D1Got282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,388,773 - 237,389,007 (-)MAPPERmRatBN7.2
Rnor_6.01147,422,697 - 147,422,934NCBIRnor6.0
Rnor_5.01153,717,763 - 153,718,000UniSTSRnor5.0
RGSC_v3.41244,028,192 - 244,028,426UniSTSRGSC3.4
RGSC_v3.41243,702,202 - 243,702,423UniSTSRGSC3.4
RGSC_v3.41244,028,191 - 244,028,426RGDRGSC3.4
RGSC_v3.11244,124,750 - 244,124,985RGD
RH 3.4 Map11617.12UniSTS
RH 3.4 Map11617.12RGD
RH 2.0 Map11222.3RGD
Cytogenetic Map1q53UniSTS
RH134367  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21238,503,991 - 238,504,198 (+)MAPPERmRatBN7.2
mRatBN7.21237,388,393 - 237,388,600 (-)MAPPERmRatBN7.2
Rnor_6.01147,423,108 - 147,423,314NCBIRnor6.0
Rnor_6.01148,287,138 - 148,287,344NCBIRnor6.0
Rnor_5.01154,573,938 - 154,574,144UniSTSRnor5.0
Rnor_5.01153,718,174 - 153,718,380UniSTSRnor5.0
Cytogenetic Map1q53UniSTS
AU048831  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21238,462,568 - 238,462,821 (+)MAPPERmRatBN7.2
Rnor_6.01148,245,719 - 148,245,971NCBIRnor6.0
Rnor_5.01154,533,195 - 154,533,442UniSTSRnor5.0
RGSC_v3.41243,972,787 - 243,973,057UniSTSRGSC3.4
RGSC_v3.41244,580,731 - 244,580,983UniSTSRGSC3.4
Celera1137,219,180 - 137,219,432UniSTS
Cytogenetic Map1q53UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 8 14 39 69 66 41 20 41 4 126 51 23 23 36 25

Sequence


Ensembl Acc Id: ENSRNOT00000040325   ⟹   ENSRNOP00000045029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,332,659 - 237,388,709 (+)Ensembl
Rnor_6.0 Ensembl1148,053,687 - 148,119,857 (-)Ensembl
RefSeq Acc Id: NM_017158   ⟹   NP_058854
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,966,394 - 248,022,388 (+)NCBI
mRatBN7.21237,332,762 - 237,388,709 (+)NCBI
Rnor_6.01147,422,999 - 148,119,857 (-)NCBI
Rnor_5.01154,329,783 - 154,407,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105249   ⟹   XP_038961177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,973,260 - 248,022,393 (+)NCBI
mRatBN7.21237,339,694 - 237,388,706 (+)NCBI
RefSeq Acc Id: XM_063284310   ⟹   XP_063140380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,966,295 - 248,017,760 (+)NCBI
RefSeq Acc Id: NP_058854   ⟸   NM_017158
- Peptide Label: precursor
- UniProtKB: Q63706 (UniProtKB/Swiss-Prot),   P05179 (UniProtKB/Swiss-Prot),   Q4QQW7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045029   ⟸   ENSRNOT00000040325
RefSeq Acc Id: XP_038961177   ⟸   XM_039105249
- Peptide Label: isoform X1
- UniProtKB: Q4QQW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140380   ⟸   XM_063284310
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05179-F1-model_v2 AlphaFold P05179 1-490 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690174
Promoter ID:EPDNEW_R698
Type:multiple initiation site
Name:Cyp2c7_1
Description:cytochrome P450, family 2, subfamily c, polypeptide 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01148,119,857 - 148,119,917EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620379 AgrOrtholog
BioCyc Gene G2FUF-55758 BioCyc
Ensembl Genes ENSRNOG00000021405 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000095788 ENTREZGENE
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7368637 IMAGE-MGC_LOAD
  IMAGE:7371672 IMAGE-MGC_LOAD
InterPro Cyt_P450 UniProtKB/Swiss-Prot
  Cyt_P450_CS UniProtKB/Swiss-Prot
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot
  Cyt_P450_sf UniProtKB/Swiss-Prot
  Cytochrome_P450_fam2 UniProtKB/Swiss-Prot
KEGG Report rno:29298 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116058 IMAGE-MGC_LOAD
  MGC:156667 IMAGE-MGC_LOAD
NCBI Gene 29298 ENTREZGENE
PANTHER CYTOCHROME P450 2C29-RELATED UniProtKB/Swiss-Prot
  CYTOCHROME P450 508A4-RELATED UniProtKB/Swiss-Prot
Pfam p450 UniProtKB/Swiss-Prot
PhenoGen Cyp2c7 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot
  P450 UniProtKB/Swiss-Prot
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021405 RatGTEx
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot
UniProt A0A8I6A341_RAT UniProtKB/TrEMBL
  CP2C7_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q4QQW7 ENTREZGENE, UniProtKB/TrEMBL
  Q63706 ENTREZGENE
UniProt Secondary Q63706 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  LOC103691183  uncharacterized LOC103691183  Data merged from RGD:9275501 737654 PROVISIONAL
2015-07-29 LOC103691183  uncharacterized LOC103691183  LOC100911791  cytochrome P450 2C7-like  Data merged from RGD:6491095 737654 PROVISIONAL
2015-07-29 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  LOC100911552  cytochrome P450 2C7-like  Data merged from RGD:6492505 737654 PROVISIONAL
2014-08-25 LOC103691183  uncharacterized LOC103691183      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-04-12 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  LOC100361347  cytochrome P450 2C7-like  Data merged from RGD:2320318 737654 PROVISIONAL
2012-07-05 LOC100911552  cytochrome P450 2C7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911791  cytochrome P450 2C7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-05 LOC100361347  cytochrome P450 2C7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  Cyp2c39  cytochrome P450, 2c39  Symbol and Name updated 1299863 APPROVED
2002-08-07 Cyp2c39  cytochrome P450, 2c39      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expression upregulated up through 4 weeks of age 632587