Hnrnpm (heterogeneous nuclear ribonucleoprotein M) - Rat Genome Database

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Gene: Hnrnpm (heterogeneous nuclear ribonucleoprotein M) Rattus norvegicus
Analyze
Symbol: Hnrnpm
Name: heterogeneous nuclear ribonucleoprotein M
RGD ID: 620369
Description: Enables calcium-dependent protein binding activity and protein antigen binding activity. Involved in several processes, including cellular response to carcinoembryonic antigen; cellular response to lipopolysaccharide; and positive regulation of protein localization. Located in cell surface. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human HNRNPM (heterogeneous nuclear ribonucleoprotein M); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hnRNP M; Hnrpm; Hnrpm4; M4 protein; MGC109545
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8715,140,877 - 15,178,871 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl715,129,287 - 15,178,871 (-)EnsemblGRCr8
mRatBN7.2714,438,703 - 14,476,781 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl714,438,688 - 14,476,762 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx717,447,326 - 17,485,310 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0719,312,377 - 19,350,433 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0717,192,913 - 17,230,901 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0718,516,253 - 18,554,536 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)Ensemblrn6Rnor6.0
Rnor_5.0718,693,853 - 18,731,993 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4716,150,060 - 16,188,054 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera713,337,407 - 13,375,335 (-)NCBICelera
RGSC_v3.1716,150,062 - 16,188,046 (-)NCBI
Cytogenetic Map7q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
3',5'-cyclic UMP  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
7,12-dimethyltetraphene  (EXP)
actinomycin D  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
fenpyroximate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
glyphosate  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
isoflavones  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
linsidomine  (EXP)
lipopolysaccharide  (EXP,ISO)
mancozeb  (ISO)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
picoxystrobin  (ISO)
pterostilbene  (ISO)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thifluzamide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichloroethene  (EXP)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
catalytic step 2 spliceosome  (IEA,ISO)
cell surface  (IDA)
cytoplasm  (IBA)
glutamatergic synapse  (EXP,IDA,IEP,IMP)
nuclear matrix  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA)
paraspeckles  (IEA,ISO)
postsynaptic density  (EXP,IDA,IEP)
ribonucleoprotein complex  (IBA,IEA)
spliceosomal complex  (IEA,ISO)
synapse  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Surface expression of heterogeneous nuclear RNA binding protein M4 on Kupffer cell relates to its function as a carcinoembryonic antigen receptor. Bajenova O, etal., Exp Cell Res. 2003 Nov 15;291(1):228-41.
2. Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells. Bajenova OV, etal., J Biol Chem 2001 Aug 17;276(33):31067-73.
3. Identification of HnRNP M as a novel biomarker for colorectal carcinoma by quantitative proteomics. Chen S, etal., Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1;306(5):G394-403. doi: 10.1152/ajpgi.00328.2013. Epub 2013 Dec 31.
4. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
5. A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins. Cuervo AM, etal., J Biol Chem. 1997 Feb 28;272(9):5606-15.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Rhythmic serotonin N-acetyltransferase mRNA degradation is essential for the maintenance of its circadian oscillation. Kim TD, etal., Mol Cell Biol. 2005 Apr;25(8):3232-46.
9. Microarray study of gene expression in uterine leiomyoma. Litovkin KV, etal., Exp Oncol. 2008 Jun;30(2):106-11.
10. hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures. Marko M, etal., Exp Cell Res. 2010 Feb 1;316(3):390-400. doi: 10.1016/j.yexcr.2009.10.021. Epub 2009 Oct 27.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
16. RNA binding proteins accumulate at the postsynaptic density with synaptic activity. Zhang G, etal., J Neurosci. 2012 Jan 11;32(2):599-609. doi: 10.1523/JNEUROSCI.2463-11.2012.
Additional References at PubMed
PMID:9731529   PMID:10947964   PMID:11984006   PMID:11991638   PMID:12477932   PMID:15489334   PMID:16128803   PMID:19946888   PMID:22082260   PMID:22658674   PMID:22681889   PMID:23533145  
PMID:23658023   PMID:23979707   PMID:24625528   PMID:29476059   PMID:30053369   PMID:35352799  


Genomics

Comparative Map Data
Hnrnpm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8715,140,877 - 15,178,871 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl715,129,287 - 15,178,871 (-)EnsemblGRCr8
mRatBN7.2714,438,703 - 14,476,781 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl714,438,688 - 14,476,762 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx717,447,326 - 17,485,310 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0719,312,377 - 19,350,433 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0717,192,913 - 17,230,901 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0718,516,253 - 18,554,536 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)Ensemblrn6Rnor6.0
Rnor_5.0718,693,853 - 18,731,993 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4716,150,060 - 16,188,054 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera713,337,407 - 13,375,335 (-)NCBICelera
RGSC_v3.1716,150,062 - 16,188,046 (-)NCBI
Cytogenetic Map7q13NCBI
HNRNPM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,444,975 - 8,489,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl198,444,767 - 8,489,114 (+)Ensemblhg38GRCh38
GRCh37198,509,859 - 8,553,998 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36198,415,803 - 8,459,998 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34198,415,650 - 8,459,994NCBI
Celera198,367,796 - 8,411,661 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef198,165,461 - 8,209,438 (+)NCBIHuRef
CHM1_1198,509,226 - 8,553,070 (+)NCBICHM1_1
T2T-CHM13v2.0198,432,898 - 8,476,696 (+)NCBIT2T-CHM13v2.0
Hnrnpm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391733,865,207 - 33,904,432 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1733,865,207 - 33,905,834 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381733,646,233 - 33,685,458 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,646,233 - 33,686,860 (-)Ensemblmm10GRCm38
MGSCv371733,783,178 - 33,822,403 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361733,252,927 - 33,292,090 (-)NCBIMGSCv36mm8
Celera1736,401,579 - 36,440,923 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Hnrnpm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955563934,083 - 974,620 (-)Ensembl
ChiLan1.0NW_004955563933,824 - 975,064 (-)NCBIChiLan1.0ChiLan1.0
HNRNPM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22013,113,011 - 13,157,166 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11912,230,568 - 12,274,708 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,731,828 - 7,776,101 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,579,206 - 8,624,029 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl198,579,211 - 8,624,029 (+)EnsemblpanPan2panpan1.1
HNRNPM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,993,934 - 53,034,608 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2052,993,824 - 53,034,606 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2052,795,007 - 52,835,710 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02053,521,997 - 53,562,739 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2053,521,888 - 53,562,740 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,723,883 - 52,764,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,169,742 - 53,210,895 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,401,382 - 53,442,032 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hnrnpm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118212,550,835 - 212,612,298 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365885,241,613 - 5,283,689 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049365885,222,509 - 5,239,890 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365885,241,276 - 5,283,952 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl270,813,745 - 70,862,586 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1270,813,745 - 70,858,903 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,180,163 - 71,225,248 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,795,996 - 7,839,506 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl67,796,045 - 7,839,244 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607412,421,268 - 12,463,541 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hnrnpm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248281,199,048 - 1,250,887 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hnrnpm
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11158,720,911 - 158,758,766 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hnrnpm
115 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:376
Count of miRNA genes:135
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000011047, ENSRNOT00000036172, ENSRNOT00000059985
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
RH132782  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,476,872 - 14,477,081 (+)MAPPERmRatBN7.2
Rnor_6.0718,554,423 - 18,554,631NCBIRnor6.0
Rnor_5.0718,732,023 - 18,732,231UniSTSRnor5.0
RGSC_v3.4716,188,229 - 16,188,437UniSTSRGSC3.4
Celera713,375,510 - 13,375,718UniSTS
Cytogenetic Map7q12UniSTS
RH143889  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,447,602 - 14,447,821 (+)MAPPERmRatBN7.2
Rnor_6.0718,525,154 - 18,525,372NCBIRnor6.0
Rnor_5.0718,702,754 - 18,702,972UniSTSRnor5.0
RGSC_v3.4716,158,960 - 16,159,178UniSTSRGSC3.4
Celera713,346,241 - 13,346,459UniSTS
RH 3.4 Map769.0UniSTS
Cytogenetic Map7q12UniSTS
RH143934  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,439,870 - 14,440,027 (+)MAPPERmRatBN7.2
Rnor_6.0718,517,421 - 18,517,577NCBIRnor6.0
Rnor_5.0718,695,021 - 18,695,177UniSTSRnor5.0
RGSC_v3.4716,151,228 - 16,151,384UniSTSRGSC3.4
Celera713,338,575 - 13,338,731UniSTS
Cytogenetic Map7q12UniSTS
RH144620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2714,465,711 - 14,465,896 (+)MAPPERmRatBN7.2
Rnor_6.0718,543,262 - 18,543,446NCBIRnor6.0
Rnor_5.0718,720,862 - 18,721,046UniSTSRnor5.0
RGSC_v3.4716,177,068 - 16,177,252UniSTSRGSC3.4
Celera713,364,349 - 13,364,533UniSTS
RH 3.4 Map796.3UniSTS
Cytogenetic Map7q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011047   ⟹   ENSRNOP00000011047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl715,140,880 - 15,178,871 (-)Ensembl
mRatBN7.2 Ensembl714,438,708 - 14,476,762 (-)Ensembl
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000036172   ⟹   ENSRNOP00000032108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl715,140,880 - 15,178,871 (-)Ensembl
mRatBN7.2 Ensembl714,438,708 - 14,476,762 (-)Ensembl
Rnor_6.0 Ensembl718,516,512 - 18,554,227 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094545   ⟹   ENSRNOP00000084866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl715,129,287 - 15,178,871 (-)Ensembl
mRatBN7.2 Ensembl714,438,688 - 14,476,724 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096470   ⟹   ENSRNOP00000080170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl715,140,880 - 15,178,871 (-)Ensembl
mRatBN7.2 Ensembl714,438,706 - 14,476,719 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102040   ⟹   ENSRNOP00000087580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl715,141,372 - 15,178,871 (-)Ensembl
mRatBN7.2 Ensembl714,440,323 - 14,476,724 (-)Ensembl
RefSeq Acc Id: NM_001109911   ⟹   NP_001103381
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,178,871 (-)NCBI
mRatBN7.2714,438,703 - 14,476,698 (-)NCBI
Rnor_6.0718,516,253 - 18,554,248 (-)NCBI
Rnor_5.0718,693,853 - 18,731,993 (-)NCBI
RGSC_v3.4716,150,060 - 16,188,054 (-)RGD
Celera713,337,407 - 13,375,335 (-)RGD
Sequence:
RefSeq Acc Id: NM_053876   ⟹   NP_446328
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,178,871 (-)NCBI
mRatBN7.2714,438,703 - 14,476,698 (-)NCBI
Rnor_6.0718,516,253 - 18,554,248 (-)NCBI
Rnor_5.0718,693,853 - 18,731,993 (-)NCBI
RGSC_v3.4716,150,060 - 16,188,054 (-)RGD
Celera713,337,407 - 13,375,335 (-)RGD
Sequence:
RefSeq Acc Id: XM_063262869   ⟹   XP_063118939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,164,959 (-)NCBI
RefSeq Acc Id: XM_063262870   ⟹   XP_063118940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,140,877 - 15,164,959 (-)NCBI
RefSeq Acc Id: NP_446328   ⟸   NM_053876
- Peptide Label: isoform b
- UniProtKB: Q5M815 (UniProtKB/Swiss-Prot),   Q62826 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001103381   ⟸   NM_001109911
- Peptide Label: isoform a
- UniProtKB: A6KQH2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032108   ⟸   ENSRNOT00000036172
Ensembl Acc Id: ENSRNOP00000011047   ⟸   ENSRNOT00000011047
Ensembl Acc Id: ENSRNOP00000084866   ⟸   ENSRNOT00000094545
Ensembl Acc Id: ENSRNOP00000080170   ⟸   ENSRNOT00000096470
Ensembl Acc Id: ENSRNOP00000087580   ⟸   ENSRNOT00000102040
RefSeq Acc Id: XP_063118940   ⟸   XM_063262870
- Peptide Label: isoform X2
- UniProtKB: A6KQH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118939   ⟸   XM_063262869
- Peptide Label: isoform X1
- UniProtKB: A6KQH3 (UniProtKB/TrEMBL)
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62826-F1-model_v2 AlphaFold Q62826 1-690 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695082
Promoter ID:EPDNEW_R5607
Type:initiation region
Name:Hnrnpm_1
Description:heterogeneous nuclear ribonucleoprotein M
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0718,554,248 - 18,554,308EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620369 AgrOrtholog
BioCyc Gene G2FUF-34713 BioCyc
Ensembl Genes ENSRNOG00000007921 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000011047 ENTREZGENE
  ENSRNOT00000036172 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7325202 IMAGE-MGC_LOAD
InterPro HnRNP_M_PY-NLS UniProtKB/Swiss-Prot
  hnRNPM_RRM3 UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  RRT5_SRSF_SR UniProtKB/Swiss-Prot
KEGG Report rno:116655 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109545 IMAGE-MGC_LOAD
NCBI Gene 116655 ENTREZGENE
PANTHER RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam HnRNP_M UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
PhenoGen Hnrnpm PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007921 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt A0A8I5ZQ38_RAT UniProtKB/TrEMBL
  A0A8I6A4N0_RAT UniProtKB/TrEMBL
  A0A8I6GC87_RAT UniProtKB/TrEMBL
  A6KQH2 ENTREZGENE, UniProtKB/TrEMBL
  A6KQH3 ENTREZGENE, UniProtKB/TrEMBL
  A6KQH4_RAT UniProtKB/TrEMBL
  F1LV13_RAT UniProtKB/TrEMBL
  F1M3D3_RAT UniProtKB/TrEMBL
  HNRPM_RAT UniProtKB/Swiss-Prot
  Q5M815 ENTREZGENE
  Q62826 ENTREZGENE
UniProt Secondary Q5M815 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-13 Hnrnpm  heterogeneous nuclear ribonucleoprotein M  Hnrpm  heterogeneous nuclear ribonucleoprotein M  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Hnrpm  heterogeneous nuclear ribonucleoprotein M      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Hnrpm  heterogeneous nuclear ribonucleoprotein M      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains 3 putative RNA-binding domains, an arginine/methionine/glutamine-rich C terminus and 3 potential membrane spanning regions 632922
gene_protein a 78-kDa membrane protein 632922
gene_transcript 2.4-kilobase transcript 632922