Atp5pb (ATP synthase peripheral stalk-membrane subunit b) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Atp5pb (ATP synthase peripheral stalk-membrane subunit b) Rattus norvegicus
Analyze
Symbol: Atp5pb
Name: ATP synthase peripheral stalk-membrane subunit b
RGD ID: 620041
Description: Contributes to ATP hydrolysis activity. Involved in cellular response to hypoxia. Part of proton-transporting ATP synthase complex. Orthologous to human ATP5PB (ATP synthase peripheral stalk-membrane subunit b); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP synthase F(0) complex subunit B1, mitochondrial; ATP synthase peripheral stalk subunit b, mitochondrial; ATP synthase subunit b; ATP synthase subunit b, mitochondrial; ATP synthase subunit b, mitochondrial-like; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1; Atp5f1; ATPase subunit b; LOC100911417
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82196,112,459 - 196,123,737 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2196,112,108 - 196,124,387 (-)EnsemblGRCr8
mRatBN7.22193,424,138 - 193,435,418 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2193,424,047 - 193,435,418 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2201,018,609 - 201,029,888 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02198,914,310 - 198,925,477 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02193,731,277 - 193,742,444 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02208,566,385 - 208,577,147 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,566,385 - 208,577,146 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl2208,408,890 - 208,420,163 (-)Ensemblrn6Rnor6.0
Rnor_5.02227,987,601 - 227,998,363 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42201,195,390 - 201,206,585 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2186,126,257 - 186,137,862 (-)NCBICelera
RGSC_v3.12201,158,143 - 201,169,339 (-)NCBI
Cytogenetic Map2q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Systematic Analysis of the Expression of the Mitochondrial ATP Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma. Brüggemann M, etal., Transl Oncol. 2017 Aug;10(4):661-668. doi: 10.1016/j.tranon.2017.06.002. Epub 2017 Jun 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). Ko YH, etal., J Biol Chem. 2000 Oct 20;275(42):32931-9.
6. Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma. Lee CF, etal., World J Gastroenterol. 2008 Oct 21;14(39):6072-7. doi: 10.3748/wjg.14.6072.
7. Identification of two proteins associated with mammalian ATP synthase. Meyer B, etal., Mol Cell Proteomics. 2007 Oct;6(10):1690-9. Epub 2007 Jun 17.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15. cDNA cloning and sequencing for the import precursor of subunit B in H(+)-ATP synthase from rat mitochondria. Tsurumi C, etal., Biochem Biophys Res Commun 1990 May 31;169(1):136-42.
16. iTRAQ-Based Proteomic Analysis Reveals Recovery of Impaired Mitochondrial Function in Ischemic Myocardium by Shenmai Formula. Wang Y, etal., J Proteome Res. 2018 Feb 2;17(2):794-803. doi: 10.1021/acs.jproteome.7b00450. Epub 2018 Jan 23.
Additional References at PubMed
PMID:8889548   PMID:12110673   PMID:12865426   PMID:14651853   PMID:15489334   PMID:17634366   PMID:18614015   PMID:19946888   PMID:20833797   PMID:21630459   PMID:22926577   PMID:23376485  
PMID:24625528   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Atp5pb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82196,112,459 - 196,123,737 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2196,112,108 - 196,124,387 (-)EnsemblGRCr8
mRatBN7.22193,424,138 - 193,435,418 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2193,424,047 - 193,435,418 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2201,018,609 - 201,029,888 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02198,914,310 - 198,925,477 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02193,731,277 - 193,742,444 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02208,566,385 - 208,577,147 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,566,385 - 208,577,146 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl2208,408,890 - 208,420,163 (-)Ensemblrn6Rnor6.0
Rnor_5.02227,987,601 - 227,998,363 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42201,195,390 - 201,206,585 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2186,126,257 - 186,137,862 (-)NCBICelera
RGSC_v3.12201,158,143 - 201,169,339 (-)NCBI
Cytogenetic Map2q34NCBI
ATP5PB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,449,464 - 111,462,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1111,448,111 - 111,465,941 (+)Ensemblhg38GRCh38
GRCh371111,992,086 - 112,005,395 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,793,266 - 111,806,063 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341111,703,807 - 111,716,113NCBI
Celera1110,238,666 - 110,251,462 (+)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1109,863,192 - 109,875,988 (+)NCBIHuRef
CHM1_11112,106,752 - 112,119,548 (+)NCBICHM1_1
T2T-CHM13v2.01111,464,148 - 111,477,456 (+)NCBIT2T-CHM13v2.0
Atp5pb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393105,850,014 - 105,866,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3105,850,014 - 105,867,415 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383105,942,698 - 105,959,263 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3105,942,698 - 105,960,099 (-)Ensemblmm10GRCm38
MGSCv373105,745,781 - 105,763,166 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363106,070,919 - 106,088,304 (-)NCBIMGSCv36mm8
Celera3108,133,284 - 108,150,668 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map346.46NCBI
Atp5pb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543514,940,434 - 14,954,310 (+)Ensembl
ChiLan1.0NW_00495543514,940,502 - 14,952,423 (+)NCBIChiLan1.0ChiLan1.0
ATP5PB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21115,561,891 - 115,578,385 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11114,715,332 - 114,727,197 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01114,110,749 - 114,122,715 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,224,308 - 126,236,596 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,224,725 - 126,235,897 (-)EnsemblpanPan2panpan1.1
LOC100688796
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11763,940,486 - 63,954,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,613,415 - 40,625,979 (-)EnsemblcanFam3CanFam3.1
CanFam3.1 Ensembl640,613,415 - 40,625,979 (-)NCBIcanFam3CanFam3.1
Dog10K_Boxer_Tasha1763,454,097 - 63,461,699 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
Atp5pb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505817,342,222 - 17,357,091 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936690120,561 - 136,795 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936690120,572 - 135,509 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP5PB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4108,896,057 - 108,907,805 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.14108,896,063 - 108,907,626 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24119,078,642 - 119,090,149 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP5PB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12022,150,488 - 22,162,740 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2022,150,239 - 22,162,312 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603836,316,725 - 36,328,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp5pb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247727,167,147 - 7,179,273 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247727,167,074 - 7,178,756 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Atp5pb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1352,170,426 - 52,181,796 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Atp5pb
137 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2191709311217961898Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2124537199209621565Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2191709311217961898Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2192287802221089121Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat

Markers in Region
AW531304  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22193,424,258 - 193,424,459 (+)MAPPERmRatBN7.2
Rnor_6.02208,566,506 - 208,566,706NCBIRnor6.0
Rnor_6.02208,409,011 - 208,409,211NCBIRnor6.0
Rnor_5.02227,987,722 - 227,987,922UniSTSRnor5.0
Rnor_5.02227,830,501 - 227,830,701UniSTSRnor5.0
RGSC_v3.42201,195,509 - 201,195,709UniSTSRGSC3.4
Celera2186,126,378 - 186,126,578UniSTS
RH 3.4 Map21372.0UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 6 55 130 28 30 17 84 17 253 154 11 125 67 72 13 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_134365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC063808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK845764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021920   ⟹   ENSRNOP00000021920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2196,112,461 - 196,123,736 (-)Ensembl
mRatBN7.2 Ensembl2193,424,047 - 193,435,349 (-)Ensembl
Rnor_6.0 Ensembl2208,408,890 - 208,420,163 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075083   ⟹   ENSRNOP00000065147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2196,112,461 - 196,120,139 (-)Ensembl
mRatBN7.2 Ensembl2193,424,047 - 193,431,820 (-)Ensembl
Rnor_6.0 Ensembl2208,566,385 - 208,577,146 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,576,214 - 208,577,053 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075982   ⟹   ENSRNOP00000068400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2196,112,461 - 196,123,640 (-)Ensembl
mRatBN7.2 Ensembl2193,424,056 - 193,435,321 (-)Ensembl
Rnor_6.0 Ensembl2208,569,469 - 208,576,705 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,573,290 - 208,577,043 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076556   ⟹   ENSRNOP00000067965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2196,112,108 - 196,123,737 (-)Ensembl
mRatBN7.2 Ensembl2193,424,676 - 193,435,418 (-)Ensembl
Rnor_6.0 Ensembl2208,411,969 - 208,419,722 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,415,791 - 208,420,060 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,419,231 - 208,420,070 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126288   ⟹   ENSRNOP00000110796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2196,112,461 - 196,124,387 (-)Ensembl
RefSeq Acc Id: NM_134365   ⟹   NP_599192
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82196,112,459 - 196,123,737 (-)NCBI
mRatBN7.22193,424,138 - 193,435,418 (-)NCBI
Rnor_6.02208,566,385 - 208,577,147 (-)NCBI
Rnor_5.02227,987,601 - 227,998,363 (-)NCBI
RGSC_v3.42201,195,390 - 201,206,585 (-)RGD
Celera2186,126,257 - 186,137,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039101623   ⟹   XP_038957551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82196,112,459 - 196,123,290 (-)NCBI
mRatBN7.22193,424,138 - 193,435,337 (-)NCBI
RefSeq Acc Id: NP_599192   ⟸   NM_134365
- Peptide Label: precursor
- UniProtKB: P19511 (UniProtKB/Swiss-Prot),   A6HUP1 (UniProtKB/TrEMBL),   A0A8L2QWG8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068400   ⟸   ENSRNOT00000075982
Ensembl Acc Id: ENSRNOP00000065147   ⟸   ENSRNOT00000075083
RefSeq Acc Id: XP_038957551   ⟸   XM_039101623
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QWG8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000067965   ⟸   ENSRNOT00000076556
Ensembl Acc Id: ENSRNOP00000021920   ⟸   ENSRNOT00000021920
Ensembl Acc Id: ENSRNOP00000110796   ⟸   ENSRNOT00000126288

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19511-F1-model_v2 AlphaFold P19511 1-256 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691649
Promoter ID:EPDNEW_R2172
Type:initiation region
Name:LOC100911417_1
Description:ATP synthase subunit b, mitochondrial-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02208,577,078 - 208,577,138EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620041 AgrOrtholog
BioCyc Gene G2FUF-51717 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000016000 Ensembl
  ENSRNOG00000046299 Ensembl
  ENSRNOG00000064742 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021920 ENTREZGENE
  ENSRNOT00000021920.7 UniProtKB/Swiss-Prot
  ENSRNOT00000075083 ENTREZGENE
Gene3D-CATH 1.20.5.2210 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6920021 IMAGE-MGC_LOAD
InterPro ATP_synth_Bsub_B/MI25 UniProtKB/Swiss-Prot
  ATP_synth_F0_suB UniProtKB/Swiss-Prot
KEGG Report rno:171375 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72698 IMAGE-MGC_LOAD
NCBI Gene 171375 ENTREZGENE
PANTHER ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR12733 UniProtKB/Swiss-Prot
Pfam Mt_ATP-synt_B UniProtKB/Swiss-Prot
PhenoGen Atp5pb PhenoGen
RatGTEx ENSRNOG00000016000 RatGTEx
  ENSRNOG00000046299 RatGTEx
  ENSRNOG00000064742 RatGTEx
Superfamily-SCOP ATP synthase B chain-like UniProtKB/Swiss-Prot
UniProt A0A096MJ25_RAT UniProtKB/TrEMBL
  A0A096MK68_RAT UniProtKB/TrEMBL
  A0A8L2QWG8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LIR4_RAT UniProtKB/TrEMBL
  A6HUP1 ENTREZGENE, UniProtKB/TrEMBL
  AT5F1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Atp5pb  ATP synthase peripheral stalk-membrane subunit b  LOC100911417  ATP synthase subunit b, mitochondrial-like  Data merged from RGD:6493308 737654 PROVISIONAL
2017-11-30 Atp5pb  ATP synthase peripheral stalk-membrane subunit b  Atp5f1  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911417  ATP synthase subunit b, mitochondrial-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-12-01 Atp5f1  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1  Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1  Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein contains a mitochondrial import signal 631941