Dscam (DS cell adhesion molecule) - Rat Genome Database

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Gene: Dscam (DS cell adhesion molecule) Rattus norvegicus
Analyze
Symbol: Dscam
Name: DS cell adhesion molecule
RGD ID: 619992
Description: Predicted to enable cell-cell adhesion mediator activity; netrin receptor binding activity; and protein tyrosine kinase binding activity. Involved in positive regulation of axon extension involved in axon guidance. Predicted to be located in dendrite; growth cone; and synapse. Predicted to be active in axon; neuronal cell body; and plasma membrane. Orthologous to human DSCAM (DS cell adhesion molecule); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cell adhesion molecule DSCAM; Down syndrome cell adhesion molecule; Down syndrome cell adhesion molecule homolog; Down syndrome cell adhesion molecule-like; LOC100360483; LOC686040; similar to Down syndrome cell adhesion molecule
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81149,391,385 - 49,976,861 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1149,347,531 - 49,976,238 (-)EnsemblGRCr8
mRatBN7.21135,921,924 - 36,507,100 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,926,896 - 36,507,415 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1144,576,796 - 45,149,722 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,248,172 - 37,821,087 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,401,719 - 36,980,976 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01137,004,776 - 37,599,866 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,004,902 - 37,253,776 (-)Ensemblrn6Rnor6.0
Rnor_5.01140,530,620 - 41,112,090 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41136,954,750 - 37,230,296 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1135,824,419 - 36,395,688 (-)NCBICelera
RGSC_v3.11137,012,825 - 37,275,047 (-)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IBA,IEA,ISO,ISS)
dendrite  (IEA,ISO,ISS)
growth cone  (IEA,ISO,ISS)
neuronal cell body  (IBA,IEA,ISO,ISS)
plasma membrane  (IBA,IEA,ISO,ISS)
synapse  (IEA,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Down syndrome cell adhesion molecule is conserved in mouse and highly expressed in the adult mouse brain. Barlow GM, etal., Cytogenet Cell Genet 2001;94(3-4):155-62.
2. Down syndrome congenital heart disease: a narrowed region and a candidate gene. Barlow GM, etal., Genet Med 2001 Mar-Apr;3(2):91-101.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Ly A, etal., Cell. 2008 Jun 27;133(7):1241-54. doi: 10.1016/j.cell.2008.05.030.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Yamakawa K, etal., Hum Mol Genet 1998 Feb;7(2):227-37.
Additional References at PubMed
PMID:18216855   PMID:19196994   PMID:19558816   PMID:19945391   PMID:21360594   PMID:22685302  


Genomics

Comparative Map Data
Dscam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81149,391,385 - 49,976,861 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1149,347,531 - 49,976,238 (-)EnsemblGRCr8
mRatBN7.21135,921,924 - 36,507,100 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,926,896 - 36,507,415 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1144,576,796 - 45,149,722 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,248,172 - 37,821,087 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,401,719 - 36,980,976 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01137,004,776 - 37,599,866 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,004,902 - 37,253,776 (-)Ensemblrn6Rnor6.0
Rnor_5.01140,530,620 - 41,112,090 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41136,954,750 - 37,230,296 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1135,824,419 - 36,395,688 (-)NCBICelera
RGSC_v3.11137,012,825 - 37,275,047 (-)NCBI
Cytogenetic Map11q11NCBI
DSCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382140,010,999 - 40,847,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2140,010,999 - 40,847,158 (-)Ensemblhg38GRCh38
GRCh372141,382,926 - 42,219,084 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362140,306,213 - 41,140,909 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342140,306,212 - 41,140,909NCBI
Celera2126,582,079 - 27,417,510 (-)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2127,195,979 - 27,689,477 (-)NCBIHuRef
HuRef2126,884,190 - 27,191,292 (-)NCBIHuRef
CHM1_12140,945,084 - 41,641,065 (-)NCBICHM1_1
T2T-CHM13v2.02138,398,213 - 39,235,595 (-)NCBIT2T-CHM13v2.0
Dscam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391696,388,652 - 96,971,935 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1696,392,040 - 96,971,952 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381696,587,452 - 97,171,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1696,590,840 - 97,170,752 (-)Ensemblmm10GRCm38
MGSCv371696,813,686 - 97,392,342 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361696,697,642 - 97,275,645 (-)NCBIMGSCv36mm8
Celera1697,670,177 - 98,230,565 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.02NCBI
Dscam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540739,986,108 - 40,473,200 (-)Ensembl
ChiLan1.0NW_00495540739,985,501 - 40,473,330 (-)NCBIChiLan1.0ChiLan1.0
DSCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22236,111,075 - 36,938,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12130,966,996 - 31,793,715 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02126,366,295 - 27,192,617 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12139,699,077 - 40,054,961 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2139,699,077 - 40,524,164 (-)EnsemblpanPan2panpan1.1
DSCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13134,666,300 - 35,277,651 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3134,669,424 - 35,400,160 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3133,951,978 - 34,617,540 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03134,180,996 - 34,914,940 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3134,181,499 - 34,914,869 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13134,050,877 - 34,780,483 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03134,056,656 - 34,784,846 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03134,548,894 - 35,278,352 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dscam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497134,128,713 - 34,780,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365002,686,850 - 3,338,498 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365002,686,847 - 3,339,110 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13203,567,129 - 204,313,820 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113203,566,765 - 204,292,079 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213213,656,399 - 213,751,939 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,969,555 - 84,738,661 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605411,797,452 - 12,609,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dscam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474528,969,498 - 29,559,968 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474528,969,464 - 29,560,557 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Dscam
3852 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:22
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000002215
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
D11Rat35  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81149,578,666 - 49,578,893 (+)Marker Load Pipeline
mRatBN7.21136,109,214 - 36,109,441 (+)MAPPERmRatBN7.2
Rnor_6.01137,185,962 - 37,186,188NCBIRnor6.0
Rnor_5.01140,712,093 - 40,712,319UniSTSRnor5.0
RGSC_v3.41137,136,543 - 37,136,770RGDRGSC3.4
RGSC_v3.41137,136,544 - 37,136,770UniSTSRGSC3.4
Celera1136,007,191 - 36,007,412UniSTS
RGSC_v3.11137,194,132 - 37,194,359RGD
RH 2.0 Map11638.8RGD
SHRSP x BN Map1112.7099RGD
FHH x ACI Map1114.4199RGD
Cytogenetic Map11q12UniSTS
D11Rat108  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01137,372,263 - 37,372,397NCBIRnor6.0
Rnor_5.01140,893,271 - 40,893,405UniSTSRnor5.0
Celera1136,182,273 - 36,182,408UniSTS
SHRSP x BN Map1113.8499RGD
SHRSP x BN Map1113.8499UniSTS
Cytogenetic Map11q12UniSTS
D11Got141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21136,457,339 - 36,457,497 (+)MAPPERmRatBN7.2
Rnor_6.01137,539,942 - 37,540,099NCBIRnor6.0
Rnor_5.01141,056,012 - 41,056,169UniSTSRnor5.0
Celera1136,345,942 - 36,346,099UniSTS
Cytogenetic Map11q12UniSTS
Dscam  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,927,626 - 35,927,868 (+)MAPPERmRatBN7.2
Rnor_6.01137,005,012 - 37,005,253NCBIRnor6.0
Rnor_5.01140,530,856 - 40,531,097UniSTSRnor5.0
RGSC_v3.41136,955,464 - 36,955,705UniSTSRGSC3.4
Celera1135,824,655 - 35,824,896UniSTS
Cytogenetic Map11q12UniSTS
BE114490  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21136,107,638 - 36,107,854 (+)MAPPERmRatBN7.2
Rnor_6.01137,184,386 - 37,184,601NCBIRnor6.0
Rnor_5.01140,710,517 - 40,710,732UniSTSRnor5.0
RGSC_v3.41137,134,968 - 37,135,183UniSTSRGSC3.4
Celera1136,005,615 - 36,005,830UniSTS
RH 3.4 Map11271.0UniSTS
Cytogenetic Map11q12UniSTS
UniSTS:259605  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,927,456 - 35,927,858 (+)MAPPERmRatBN7.2
Rnor_6.01137,004,842 - 37,005,243NCBIRnor6.0
Rnor_5.01140,530,686 - 40,531,087UniSTSRnor5.0
RGSC_v3.41136,955,294 - 36,955,695UniSTSRGSC3.4
Celera1135,824,485 - 35,824,886UniSTS
Cytogenetic Map11q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 6 22 157 50 49 19 35 19 6 146 79 6 135 34 89 30 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002215   ⟹   ENSRNOP00000002215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,396,856 - 49,643,716 (-)Ensembl
mRatBN7.2 Ensembl1135,927,403 - 36,174,266 (-)Ensembl
Rnor_6.0 Ensembl1137,004,902 - 37,253,776 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094934   ⟹   ENSRNOP00000085284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,396,856 - 49,976,238 (-)Ensembl
mRatBN7.2 Ensembl1135,927,403 - 36,507,415 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109924   ⟹   ENSRNOP00000093940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,395,969 - 49,976,238 (-)Ensembl
mRatBN7.2 Ensembl1135,926,896 - 36,507,415 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123090   ⟹   ENSRNOP00000105780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,347,531 - 49,976,238 (-)Ensembl
RefSeq Acc Id: NM_133587   ⟹   NP_598271
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,396,844 - 49,976,515 (-)NCBI
mRatBN7.21135,927,391 - 36,507,100 (-)NCBI
Rnor_6.01137,004,776 - 37,599,866 (-)NCBI
Rnor_5.01140,530,620 - 41,112,090 (-)NCBI
Celera1135,824,419 - 36,395,688 (-)RGD
Sequence:
RefSeq Acc Id: XM_039087935   ⟹   XP_038943863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,869,355 (-)NCBI
mRatBN7.21135,921,924 - 36,399,923 (-)NCBI
RefSeq Acc Id: XM_039087936   ⟹   XP_038943864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,976,859 (-)NCBI
mRatBN7.21135,921,924 - 36,507,019 (-)NCBI
RefSeq Acc Id: XM_039087937   ⟹   XP_038943865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,631,868 (-)NCBI
mRatBN7.21135,921,924 - 36,162,541 (-)NCBI
RefSeq Acc Id: XM_039087938   ⟹   XP_038943866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,454,292 - 49,976,859 (-)NCBI
mRatBN7.21135,984,833 - 36,506,774 (-)NCBI
RefSeq Acc Id: XM_039087939   ⟹   XP_038943867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,530,370 (-)NCBI
mRatBN7.21135,921,924 - 36,060,920 (-)NCBI
RefSeq Acc Id: XM_039087940   ⟹   XP_038943868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,530,369 (-)NCBI
mRatBN7.21135,921,924 - 36,060,920 (-)NCBI
RefSeq Acc Id: XM_039087941   ⟹   XP_038943869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,530,369 (-)NCBI
mRatBN7.21135,921,924 - 36,060,920 (-)NCBI
RefSeq Acc Id: XM_039087942   ⟹   XP_038943870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,539,144 (-)NCBI
mRatBN7.21135,921,924 - 36,063,907 (-)NCBI
RefSeq Acc Id: XM_039087943   ⟹   XP_038943871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,521,649 (-)NCBI
mRatBN7.21135,921,924 - 36,052,197 (-)NCBI
RefSeq Acc Id: XM_063270257   ⟹   XP_063126327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,391,385 - 49,530,368 (-)NCBI
RefSeq Acc Id: XM_063270258   ⟹   XP_063126328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,492,182 - 49,976,861 (-)NCBI
RefSeq Acc Id: XM_063270259   ⟹   XP_063126329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,503,669 - 49,976,861 (-)NCBI
RefSeq Acc Id: NP_598271   ⟸   NM_133587
- Peptide Label: precursor
- UniProtKB: Q8VHZ8 (UniProtKB/Swiss-Prot),   F1M9F4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002215   ⟸   ENSRNOT00000002215
RefSeq Acc Id: XP_038943864   ⟸   XM_039087936
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AL19 (UniProtKB/TrEMBL),   F1M9F4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943863   ⟸   XM_039087935
- Peptide Label: isoform X2
- UniProtKB: F1M9F4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943865   ⟸   XM_039087937
- Peptide Label: isoform X3
- UniProtKB: F1M9F4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943870   ⟸   XM_039087942
- Peptide Label: isoform X7
- UniProtKB: A6IQF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943868   ⟸   XM_039087940
- Peptide Label: isoform X6
- UniProtKB: A6IQF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943869   ⟸   XM_039087941
- Peptide Label: isoform X7
- UniProtKB: A6IQF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943867   ⟸   XM_039087939
- Peptide Label: isoform X5
- UniProtKB: A6IQF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943871   ⟸   XM_039087943
- Peptide Label: isoform X9
- UniProtKB: A6IQF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943866   ⟸   XM_039087938
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000093940   ⟸   ENSRNOT00000109924
Ensembl Acc Id: ENSRNOP00000085284   ⟸   ENSRNOT00000094934
RefSeq Acc Id: XP_063126327   ⟸   XM_063270257
- Peptide Label: isoform X8
- UniProtKB: A6IQF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126328   ⟸   XM_063270258
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063126329   ⟸   XM_063270259
- Peptide Label: isoform X11
Ensembl Acc Id: ENSRNOP00000105780   ⟸   ENSRNOT00000123090
Protein Domains
Fibronectin type-III   Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VHZ8-F1-model_v2 AlphaFold Q8VHZ8 1-2013 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619992 AgrOrtholog
BioCyc Gene G2FUF-21701 BioCyc
Ensembl Genes ENSRNOG00000027992 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000094934 ENTREZGENE
  ENSRNOT00000094934.1 UniProtKB/Swiss-Prot
  ENSRNOT00000109924 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro DSCAM/DSCAML_C UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
KEGG Report rno:171119 UniProtKB/Swiss-Prot
NCBI Gene 171119 ENTREZGENE
PANTHER CONTACTIN UniProtKB/Swiss-Prot
  PROTEIN SIDEKICK UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
  FN3_DSCAM-DSCAML_C UniProtKB/Swiss-Prot
  I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
PhenoGen Dscam PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000027992 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
  IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8I6AL19 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJ79_RAT UniProtKB/TrEMBL
  A6IQF6 ENTREZGENE, UniProtKB/TrEMBL
  DSCAM_RAT UniProtKB/Swiss-Prot
  F1M9F4 ENTREZGENE, UniProtKB/TrEMBL
  Q8VHZ8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Dscam  DS cell adhesion molecule  Dscam  Down syndrome cell adhesion molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Dscam  Down syndrome cell adhesion molecule  LOC100360483  Down syndrome cell adhesion molecule-like  Data merged from RGD:2322073 737654 PROVISIONAL
2013-04-17 Dscam  Down syndrome cell adhesion molecule  LOC686040  similar to Down syndrome cell adhesion molecule  Data merged from RGD:1586656 737654 PROVISIONAL
2010-05-06 LOC100360483  Down syndrome cell adhesion molecule-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC686040  similar to Down syndrome cell adhesion molecule      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Dscam  Down syndrome cell adhesion molecule      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Dscam  Down syndrome cell adhesion molecule      Symbol and Name status set to provisional 70820 PROVISIONAL