Rpl6 (ribosomal protein L6) - Rat Genome Database

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Gene: Rpl6 (ribosomal protein L6) Rattus norvegicus
Analyze
Symbol: Rpl6
Name: ribosomal protein L6
RGD ID: 619826
Description: Enables 5.8S rRNA binding activity; mRNA binding activity; and tRNA binding activity. Predicted to be involved in cytoplasmic translation. Located in A band. Part of cytosolic large ribosomal subunit. Orthologous to human RPL6 (ribosomal protein L6); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 60S ribosomal protein L6; large ribosomal subunit protein eL6; MGC93267; neoplasm-related protein C140
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rpl6-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,008,142 - 41,012,756 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1241,008,142 - 41,025,733 (-)EnsemblGRCr8
mRatBN7.21235,347,493 - 35,352,011 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,347,497 - 35,351,921 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1236,521,767 - 36,525,319 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,132,971 - 37,136,523 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01236,185,418 - 36,188,970 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01240,877,578 - 40,882,032 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,877,613 - 40,881,124 (-)Ensemblrn6Rnor6.0
Rnor_5.01242,744,693 - 42,749,153 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41236,483,874 - 36,487,420 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1237,011,947 - 37,015,493 (-)NCBICelera
RGSC_v3.11236,347,261 - 36,351,676 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-nitrofluorene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-tert-Octylphenol  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP,ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
chromium(6+)  (ISO)
Cinobufagin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cocaine  (EXP)
Cuprizon  (ISO)
cylindrospermopsin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
etoposide  (ISO)
eugenol  (EXP)
flavonoids  (EXP,ISO)
flutamide  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
isoniazide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methylparaben  (ISO)
miconazole  (ISO)
N-nitrosodimethylamine  (EXP)
nitrates  (ISO)
nitroglycerin  (EXP)
ochratoxin A  (EXP,ISO)
ozone  (ISO)
p-tert-Amylphenol  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (EXP)
picoxystrobin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
progesterone  (ISO)
Propiverine  (EXP)
raloxifene  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thapsigargin  (EXP)
titanium dioxide  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cytoplasmic translation  (IBA,ISO,ISS)
translation  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. The primary structure of rat ribosomal protein L6. Chan YL and Wool IG, Biochem Mol Biol Int 1996 Jun;39(3):431-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution. Horne Z and Hesketh J, Biochem J. 1990 May 15;268(1):231-6.
6. Selective high-efficiency cross-linking of mammalian ribosomal proteins with cleavable thiol-directed heterobifunctional reagents: identification and binding directions of major protein complexes. Hultin T Biochim Biophys Acta. 1986 Aug 15;872(3):226-35.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Ribosomal proteins cross-linked to natural mRNA by UV irradiation of rat liver polysomes. Takahashi Y and Ogata K, J Biochem. 1981 Nov;90(5):1549-52.
12. Identification by affinity chromatography of the eukaryotic ribosomal proteins that bind to 5.8 S ribosomal ribonucleic acid. Ulbrich N, etal., J Biol Chem. 1979 Sep 10;254(17):8641-5.
13. Separate binding sites on rat liver ribosomal protein L6 for 5 S and 5.8 S ribosomal ribonucleic acids and for transfer ribonucleic acids. Ulbrich N, etal., J Biol Chem. 1982 Oct 10;257(19):11353-7.
Additional References at PubMed
PMID:398910   PMID:8185817   PMID:12962325   PMID:15121898   PMID:15169875   PMID:15489334   PMID:16635246   PMID:19946888   PMID:21423176   PMID:21630459   PMID:22082260   PMID:22658674  
PMID:22871113   PMID:24930395   PMID:25468996   PMID:25957688   PMID:26316108   PMID:29476059   PMID:35352799  


Genomics

Comparative Map Data
Rpl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,008,142 - 41,012,756 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1241,008,142 - 41,025,733 (-)EnsemblGRCr8
mRatBN7.21235,347,493 - 35,352,011 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,347,497 - 35,351,921 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1236,521,767 - 36,525,319 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,132,971 - 37,136,523 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01236,185,418 - 36,188,970 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01240,877,578 - 40,882,032 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,877,613 - 40,881,124 (-)Ensemblrn6Rnor6.0
Rnor_5.01242,744,693 - 42,749,153 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41236,483,874 - 36,487,420 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1237,011,947 - 37,015,493 (-)NCBICelera
RGSC_v3.11236,347,261 - 36,351,676 (-)NCBI
Cytogenetic Map12q16NCBI
RPL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812112,405,181 - 112,418,835 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12112,405,170 - 112,418,844 (-)Ensemblhg38GRCh38
GRCh3712112,842,985 - 112,856,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612111,327,377 - 111,331,826 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3412111,305,714 - 111,310,141NCBI
Celera12112,470,140 - 112,474,589 (-)NCBICelera
Cytogenetic Map12q24.13NCBI
HuRef12109,855,563 - 109,860,012 (-)NCBIHuRef
CHM1_112112,811,645 - 112,816,094 (-)NCBICHM1_1
T2T-CHM13v2.012112,382,081 - 112,395,752 (-)NCBIT2T-CHM13v2.0
Rpl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,342,564 - 121,347,304 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5121,342,544 - 121,347,304 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385121,204,501 - 121,209,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5121,204,481 - 121,209,241 (+)Ensemblmm10GRCm38
MGSCv375121,654,510 - 121,659,250 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365121,465,118 - 121,469,584 (+)NCBIMGSCv36mm8
Celera5118,294,425 - 118,299,167 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map561.72NCBI
Rpl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554828,917,777 - 8,923,150 (-)NCBIChiLan1.0ChiLan1.0
RPL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210120,497,117 - 120,501,624 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112120,493,506 - 120,498,011 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012110,002,667 - 110,008,899 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112113,398,795 - 113,403,247 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12113,398,795 - 113,403,186 (-)EnsemblpanPan2panpan1.1
RPL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,970,416 - 9,975,897 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2610,088,639 - 10,094,049 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02610,210,260 - 10,215,803 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2610,210,260 - 10,214,684 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12610,184,772 - 10,190,180 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02610,248,049 - 10,253,462 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02610,295,776 - 10,301,190 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rpl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118148,085,940 - 148,103,182 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366682,583,958 - 2,587,397 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366682,584,829 - 2,588,236 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1439,303,350 - 39,309,236 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11439,302,447 - 39,309,239 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,805,405 - 41,812,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111107,648,325 - 107,650,073 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366656831,262 - 35,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474719,822,791 - 19,827,045 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474719,821,875 - 19,826,605 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rpl6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11632,615,644 - 32,620,289 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rpl6
6 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:156
Interacting mature miRNAs:170
Transcripts:ENSRNOT00000034951, ENSRNOT00000050204
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122977552242298555Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)123424347543352593Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
RH133958  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,347,651 - 35,348,064 (+)MAPPERmRatBN7.2
mRatBN7.26123,976,641 - 123,976,828 (+)MAPPERmRatBN7.2
Rnor_6.06128,738,980 - 128,739,166NCBIRnor6.0
Rnor_6.01240,877,737 - 40,878,149NCBIRnor6.0
Rnor_5.01242,744,852 - 42,745,264UniSTSRnor5.0
Rnor_5.06137,936,060 - 137,936,246UniSTSRnor5.0
RGSC_v3.46129,221,394 - 129,221,580UniSTSRGSC3.4
RGSC_v3.41236,484,031 - 36,484,443UniSTSRGSC3.4
Celera6121,447,251 - 121,447,437UniSTS
Celera1237,012,104 - 37,012,516UniSTS
RH 3.4 Map12613.0UniSTS
RH 3.4 Map12615.8UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC061784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X87107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034951   ⟹   ENSRNOP00000038065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1241,008,142 - 41,025,733 (-)Ensembl
mRatBN7.2 Ensembl1235,347,497 - 35,351,921 (-)Ensembl
Rnor_6.0 Ensembl1240,877,613 - 40,881,124 (-)Ensembl
RefSeq Acc Id: NM_053971   ⟹   NP_446423
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,008,144 - 41,011,690 (-)NCBI
mRatBN7.21235,347,495 - 35,351,041 (-)NCBI
Rnor_6.01240,877,580 - 40,881,126 (-)NCBI
Rnor_5.01242,744,693 - 42,749,153 (-)NCBI
RGSC_v3.41236,483,874 - 36,487,420 (-)RGD
Celera1237,011,947 - 37,015,493 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249378   ⟹   XP_006249440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,008,142 - 41,012,756 (-)NCBI
mRatBN7.21235,347,493 - 35,352,011 (-)NCBI
Rnor_6.01240,877,578 - 40,882,032 (-)NCBI
Rnor_5.01242,744,693 - 42,749,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089033   ⟹   XP_038944961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,008,142 - 41,012,567 (-)NCBI
mRatBN7.21235,347,493 - 35,351,874 (-)NCBI
RefSeq Acc Id: XM_039089034   ⟹   XP_038944962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,008,142 - 41,012,323 (-)NCBI
mRatBN7.21235,347,493 - 35,351,484 (-)NCBI
RefSeq Acc Id: NP_446423   ⟸   NM_053971
- UniProtKB: Q64624 (UniProtKB/Swiss-Prot),   Q4QRA9 (UniProtKB/Swiss-Prot),   Q68G26 (UniProtKB/Swiss-Prot),   P21533 (UniProtKB/Swiss-Prot),   A6J1G1 (UniProtKB/TrEMBL),   Q6P790 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249440   ⟸   XM_006249378
- Peptide Label: isoform X2
- UniProtKB: Q64624 (UniProtKB/Swiss-Prot),   Q4QRA9 (UniProtKB/Swiss-Prot),   Q68G26 (UniProtKB/Swiss-Prot),   P21533 (UniProtKB/Swiss-Prot),   A6J1G1 (UniProtKB/TrEMBL),   Q6P790 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000038065   ⟸   ENSRNOT00000034951
RefSeq Acc Id: XP_038944961   ⟸   XM_039089033
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QIW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944962   ⟸   XM_039089034
- Peptide Label: isoform X2
- UniProtKB: Q64624 (UniProtKB/Swiss-Prot),   Q4QRA9 (UniProtKB/Swiss-Prot),   P21533 (UniProtKB/Swiss-Prot),   Q68G26 (UniProtKB/Swiss-Prot),   A6J1G1 (UniProtKB/TrEMBL),   Q6P790 (UniProtKB/TrEMBL)
Protein Domains
Large ribosomal subunit protein uL6 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P21533-F1-model_v2 AlphaFold P21533 1-298 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698659
Promoter ID:EPDNEW_R9184
Type:multiple initiation site
Name:Rpl6_1
Description:ribosomal protein L6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01240,881,058 - 40,881,118EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619826 AgrOrtholog
BioCyc Gene G2FUF-19203 BioCyc
Ensembl Genes ENSRNOG00000025936 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000034951 ENTREZGENE
Gene3D-CATH 2.30.30.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5623836 IMAGE-MGC_LOAD
  IMAGE:7123086 IMAGE-MGC_LOAD
  IMAGE:7446680 IMAGE-MGC_LOAD
InterPro 60S_ribosomal_L6E UniProtKB/Swiss-Prot
  KOW_RPL6 UniProtKB/Swiss-Prot
  Rib_L2_dom2 UniProtKB/Swiss-Prot
  Ribosomal_eL6_CS UniProtKB/Swiss-Prot
  Ribosomal_L6_N UniProtKB/Swiss-Prot
  Translation_prot_SH3-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:117042 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114280 IMAGE-MGC_LOAD
  MGC:72343 IMAGE-MGC_LOAD
  MGC:93267 IMAGE-MGC_LOAD
NCBI Gene 117042 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L6 UniProtKB/Swiss-Prot
  60S RIBOSOMAL PROTEIN L6 UniProtKB/Swiss-Prot
Pfam Ribosomal_L6e UniProtKB/Swiss-Prot
  Ribosomal_L6e_N UniProtKB/Swiss-Prot
PhenoGen Rpl6 PhenoGen
PROSITE RIBOSOMAL_L6E UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000025936 RatGTEx
Superfamily-SCOP SSF50104 UniProtKB/Swiss-Prot
UniProt A0A8L2QIW0 ENTREZGENE, UniProtKB/TrEMBL
  A6J1G1 ENTREZGENE, UniProtKB/TrEMBL
  P21533 ENTREZGENE
  Q4QRA9 ENTREZGENE
  Q64624 ENTREZGENE
  Q68G26 ENTREZGENE
  Q6P790 ENTREZGENE, UniProtKB/TrEMBL
  RL6_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q4QRA9 UniProtKB/Swiss-Prot
  Q64624 UniProtKB/Swiss-Prot
  Q68G26 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Rpl6  ribosomal protein L6      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rpl6  ribosomal protein L6      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 296 amino acids 633920
gene_transcript 7 to 10 copies of the gene 633920