Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Timm44 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TIMM44 mRNA] | CTD | PMID:31150632 | Timm44 | Rat | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in decreased expression of TIMM44 mRNA | CTD | PMID:27840820 | Timm44 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Timm44 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TIMM44 mRNA | CTD | PMID:22206623 | Timm44 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of TIMM44 mRNA | CTD | PMID:29097150 | Timm44 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Timm44 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TIMM44 mRNA | CTD | PMID:21570461 | Timm44 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TIMM44 mRNA | CTD | PMID:34747641 | Timm44 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TIMM44 mRNA | CTD | PMID:30851411 | Timm44 | Rat | acrolein | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Timm44 | Rat | acrylamide | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TIMM44 mRNA | CTD | PMID:32763439 | Timm44 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | TIMM44 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of TIMM44 promoter | CTD | PMID:30157460 | Timm44 | Rat | all-trans-retinoic acid | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TIMM44 mRNA | CTD | PMID:33167477 | Timm44 | Rat | alpha-pinene | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Timm44 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TIMM44 mRNA | CTD | PMID:38685447 | Timm44 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of TIMM44 mRNA | CTD | PMID:16483693 | Timm44 | Rat | antirheumatic drug | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of TIMM44 mRNA | CTD | PMID:24449571 | Timm44 | Rat | aristolochic acid A | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TIMM44 mRNA | CTD | PMID:33212167 | Timm44 | Rat | arsane | affects methylation | ISO | TIMM44 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TIMM44 gene | CTD | PMID:25304211 | Timm44 | Rat | arsane | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Timm44 | Rat | arsenic atom | affects methylation | ISO | TIMM44 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TIMM44 gene | CTD | PMID:25304211 | Timm44 | Rat | arsenic atom | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Timm44 | Rat | benzo[a]pyrene | increases methylation | ISO | TIMM44 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TIMM44 3' UTR | CTD | PMID:27901495 | Timm44 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Timm44 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of TIMM44 mRNA | CTD | PMID:34319233 | Timm44 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TIMM44 mRNA | CTD | PMID:25181051 | Timm44 | Rat | bisphenol A | decreases expression | ISO | Timm44 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TIMM44 mRNA | CTD | PMID:33221593 | Timm44 | Rat | bisphenol A | affects expression | ISO | TIMM44 (Homo sapiens) | 6480464 | bisphenol A affects the expression of TIMM44 mRNA | CTD | PMID:30903817 | Timm44 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TIMM44 mRNA | CTD | PMID:29097150 | Timm44 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TIMM44 gene | CTD | PMID:28505145 | Timm44 | Rat | bisphenol AF | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of TIMM44 protein | CTD | PMID:34186270 | Timm44 | Rat | Bisphenol B | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of TIMM44 protein | CTD | PMID:34186270 | Timm44 | Rat | bisphenol F | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of TIMM44 protein | CTD | PMID:34186270 | Timm44 | Rat | butan-1-ol | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... | CTD | PMID:29432896 | Timm44 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of TIMM44 promoter | CTD | PMID:22457795 | Timm44 | Rat | cadmium dichloride | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TIMM44 mRNA | CTD | PMID:38568856 | Timm44 | Rat | cisplatin | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of TIMM44 mRNA | CTD | PMID:27392435 | Timm44 | Rat | cyclosporin A | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TIMM44 mRNA | CTD | PMID:20106945 | Timm44 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of TIMM44 mRNA | CTD | PMID:23914054 | Timm44 | Rat | dorsomorphin | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Timm44 | Rat | doxorubicin | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TIMM44 mRNA | CTD | PMID:29803840 | Timm44 | Rat | entinostat | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | entinostat results in increased expression of TIMM44 mRNA | CTD | PMID:26272509 | Timm44 | Rat | entinostat | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Timm44 | Rat | epoxiconazole | decreases expression | ISO | Timm44 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of TIMM44 mRNA | CTD | PMID:35436446 | Timm44 | Rat | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of TIMM44 mRNA | CTD | PMID:17920746 | Timm44 | Rat | ethanol | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... | CTD | PMID:29432896 | Timm44 | Rat | folic acid | multiple interactions | ISO | Timm44 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TIMM44 mRNA | CTD | PMID:22206623 | Timm44 | Rat | FR900359 | increases phosphorylation | ISO | TIMM44 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TIMM44 protein | CTD | PMID:37730182 | Timm44 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TIMM44 mRNA | CTD | PMID:33387578 | Timm44 | Rat | hypochlorous acid | decreases expression | ISO | Timm44 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of TIMM44 mRNA | CTD | PMID:19376150 | Timm44 | Rat | ivermectin | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TIMM44 protein | CTD | PMID:32959892 | Timm44 | Rat | leflunomide | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of TIMM44 mRNA | CTD | PMID:28988120|PMID:29427785 | Timm44 | Rat | manganese atom | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Timm44 | Rat | manganese(0) | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Timm44 | Rat | manganese(II) chloride | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Timm44 | Rat | ozone | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Timm44 | Rat | paracetamol | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TIMM44 mRNA | CTD | PMID:25704631 | Timm44 | Rat | perfluorononanoic acid | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of TIMM44 mRNA | CTD | PMID:32588087 | Timm44 | Rat | pirinixic acid | increases expression | ISO | Timm44 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TIMM44 mRNA | CTD | PMID:18301758 | Timm44 | Rat | propiconazole | decreases expression | ISO | Timm44 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TIMM44 mRNA | CTD | PMID:21278054 | Timm44 | Rat | rac-lactic acid | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TIMM44 mRNA | CTD | PMID:30851411 | Timm44 | Rat | resveratrol | increases expression | ISO | Timm44 (Mus musculus) | 6480464 | resveratrol results in increased expression of TIMM44 protein | CTD | PMID:25505154 | Timm44 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of TIMM44 protein | CTD | PMID:35544339 | Timm44 | Rat | SB 431542 | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of TIMM44 more ... | CTD | PMID:27188386|PMID:37664457 | Timm44 | Rat | silicon dioxide | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of TIMM44 mRNA | CTD | PMID:25895662 | Timm44 | Rat | sodium arsenite | multiple interactions | ISO | TIMM44 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Timm44 | Rat | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TIMM44 protein | CTD | PMID:38266420 | Timm44 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of TIMM44 mRNA | CTD | PMID:19281266 | Timm44 | Rat | sunitinib | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TIMM44 mRNA | CTD | PMID:31533062 | Timm44 | Rat | testosterone | increases expression | ISO | Timm44 (Mus musculus) | 6480464 | Testosterone results in increased expression of TIMM44 mRNA | CTD | PMID:21669218 | Timm44 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TIMM44 mRNA] | CTD | PMID:31150632 | Timm44 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TIMM44 mRNA | CTD | PMID:31150632 | Timm44 | Rat | thapsigargin | decreases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of TIMM44 mRNA | CTD | PMID:19442820 | Timm44 | Rat | thapsigargin | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of TIMM44 mRNA | CTD | PMID:22378314 | Timm44 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TIMM44 mRNA | CTD | PMID:34492290 | Timm44 | Rat | titanium dioxide | decreases methylation | ISO | Timm44 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TIMM44 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Timm44 | Rat | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to TIMM44 protein | CTD | PMID:19783845 | Timm44 | Rat | triptonide | decreases expression | ISO | Timm44 (Mus musculus) | 6480464 | triptonide results in decreased expression of TIMM44 mRNA | CTD | PMID:33045310 | Timm44 | Rat | tunicamycin | increases expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of TIMM44 mRNA | CTD | PMID:22378314|PMID:29453283 | Timm44 | Rat | valproic acid | increases methylation | ISO | TIMM44 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TIMM44 gene | CTD | PMID:29154799 | Timm44 | Rat | valproic acid | affects expression | ISO | TIMM44 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TIMM44 mRNA | CTD | PMID:25979313 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















