Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Timm23 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TIMM23 mRNA | CTD | PMID:22206623 | Timm23 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Timm23 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TIMM23 mRNA | CTD | PMID:17555576 | Timm23 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of TIMM23 mRNA | CTD | PMID:16174780 | Timm23 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TIMM23 mRNA | CTD | PMID:16174780|PMID:17942748 | Timm23 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TIMM23 mRNA | CTD | PMID:17942748 | Timm23 | Rat | 17beta-estradiol | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | Estradiol results in increased expression of TIMM23 mRNA | CTD | PMID:39298647 | Timm23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TIMM23 mRNA | CTD | PMID:17942748 | Timm23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Timm23 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TIMM23 mRNA | CTD | PMID:18343893 | Timm23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TIMM23 mRNA | CTD | PMID:17942748 | Timm23 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | ISO | Timm23 (Mus musculus) | 6480464 | 2,3,7,8-tetrachlorodibenzofuran affects the expression of TIMM23 mRNA | CTD | PMID:18343893 | Timm23 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of TIMM23 mRNA | CTD | PMID:21346803 | Timm23 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TIMM23 mRNA | CTD | PMID:30851411 | Timm23 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | bisphenol S results in increased expression of TIMM23 mRNA | CTD | PMID:39298647 | Timm23 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Timm23 | Rat | 4-hydroxyphenyl retinamide | affects expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Fenretinide affects the expression of TIMM23 mRNA | CTD | PMID:16570282 | Timm23 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Decitabine affects the expression of TIMM23 mRNA | CTD | PMID:23300844 | Timm23 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TIMM23 mRNA | CTD | PMID:30047161 | Timm23 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of TIMM23 mRNA | CTD | PMID:28959563 | Timm23 | Rat | afimoxifene | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of TIMM23 mRNA] | CTD | PMID:21233418 | Timm23 | Rat | aflatoxin B1 | decreases methylation | ISO | TIMM23 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TIMM23 gene | CTD | PMID:27153756 | Timm23 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of TIMM23 mRNA | CTD | PMID:30047161 | Timm23 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of TIMM23 mRNA | CTD | PMID:16483693 | Timm23 | Rat | arsenite(3-) | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | EIF2S1 protein mutant form inhibits the reaction [arsenite results in decreased expression of TIMM23 protein] | CTD | PMID:24315374 | Timm23 | Rat | arsenite(3-) | decreases expression | ISO | Timm23 (Mus musculus) | 6480464 | arsenite results in decreased expression of TIMM23 protein | CTD | PMID:24315374 | Timm23 | Rat | arsenite(3-) | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [TIMM17A protein binds to TIMM23 protein]; YME1L1 mutant form inhibits the more ... | CTD | PMID:24315374 | Timm23 | Rat | arsenous acid | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of TIMM23 mRNA | CTD | PMID:35676786 | Timm23 | Rat | atrazine | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of TIMM23 mRNA | CTD | PMID:22378314 | Timm23 | Rat | benzo[a]pyrene | decreases expression | ISO | Timm23 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TIMM23 mRNA | CTD | PMID:27195522 | Timm23 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | [Diethylhexyl Phthalate co-treated with Carbonyl Cyanide m-Chlorophenyl Hydrazone] results in increased degradation of TIMM23 protein | CTD | PMID:33161305 | Timm23 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TIMM23 mRNA | CTD | PMID:25181051 | Timm23 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TIMM23 mRNA | CTD | PMID:41034487 | Timm23 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Timm23 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TIMM23 mRNA | CTD | PMID:34947998 | Timm23 | Rat | bisphenol A | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TIMM23 mRNA | CTD | PMID:29275510 | Timm23 | Rat | bisphenol F | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | bisphenol F results in increased expression of TIMM23 mRNA | CTD | PMID:38685157 | Timm23 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Timm23 | Rat | cadmium atom | increases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Cadmium results in increased expression of TIMM23 mRNA | CTD | PMID:24376830 | Timm23 | Rat | cadmium atom | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMM23 more ... | CTD | PMID:37236586 | Timm23 | Rat | cadmium dichloride | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMM23 more ... | CTD | PMID:37236586 | Timm23 | Rat | carbon nanotube | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of TIMM23 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681|PMID:25620056 | Timm23 | Rat | CCCP | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of TIMM23 protein | CTD | PMID:29371327 | Timm23 | Rat | CCCP | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | [Diethylhexyl Phthalate co-treated with Carbonyl Cyanide m-Chlorophenyl Hydrazone] results in increased degradation of TIMM23 protein; more ... | CTD | PMID:33161305 | Timm23 | Rat | CGP 52608 | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TIMM23 gene] | CTD | PMID:28238834 | Timm23 | Rat | chlorpyrifos | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Chlorpyrifos results in decreased expression of TIMM23 protein | CTD | PMID:26070385 | Timm23 | Rat | chromium(6+) | affects expression | ISO | Timm23 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of TIMM23 mRNA | CTD | PMID:28472532 | Timm23 | Rat | cisplatin | affects expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Cisplatin affects the expression of TIMM23 mRNA | CTD | PMID:23300844 | Timm23 | Rat | cobalt dichloride | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TIMM23 mRNA | CTD | PMID:19376846 | Timm23 | Rat | cyclosporin A | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TIMM23 mRNA | CTD | PMID:22147139 | Timm23 | Rat | diarsenic trioxide | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of TIMM23 mRNA | CTD | PMID:35676786 | Timm23 | Rat | Dibutyl phosphate | affects expression | ISO | TIMM23 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TIMM23 mRNA | CTD | PMID:37042841 | Timm23 | Rat | dioxygen | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of TIMM23 mRNA | CTD | PMID:24236059 | Timm23 | Rat | ethanol | affects splicing | ISO | Timm23 (Mus musculus) | 6480464 | Ethanol affects the splicing of TIMM23 mRNA | CTD | PMID:30319688 | Timm23 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of TIMM23 mRNA | CTD | PMID:34044035 | Timm23 | Rat | folic acid | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TIMM23 mRNA | CTD | PMID:22206623 | Timm23 | Rat | hydrogen peroxide | affects expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of TIMM23 mRNA | CTD | PMID:20044591 | Timm23 | Rat | isobutanol | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic more ... | CTD | PMID:29432896 | Timm23 | Rat | isotretinoin | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of TIMM23 mRNA | CTD | PMID:20436886 | Timm23 | Rat | ivermectin | increases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Ivermectin results in increased expression of TIMM23 protein | CTD | PMID:32959892 | Timm23 | Rat | lamivudine | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA | CTD | PMID:18313992 | Timm23 | Rat | menadione | affects expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of TIMM23 mRNA | CTD | PMID:20044591 | Timm23 | Rat | mercury atom | increases expression | EXP | | 6480464 | Mercury results in increased expression of TIMM23 mRNA | CTD | PMID:22688007 | Timm23 | Rat | mercury(0) | increases expression | EXP | | 6480464 | Mercury results in increased expression of TIMM23 mRNA | CTD | PMID:22688007 | Timm23 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of TIMM23 mRNA | CTD | PMID:30047161 | Timm23 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Carbonyl Cyanide m-Chlorophenyl Hydrazone] results in increased degradation of TIMM23 protein; Acetylcysteine more ... | CTD | PMID:33161305 | Timm23 | Rat | N-acetyl-L-cysteine | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | Acetylcysteine inhibits the reaction [[mono-(2-ethylhexyl)phthalate co-treated with Carbonyl Cyanide m-Chlorophenyl Hydrazone] results in increased degradation more ... | CTD | PMID:33161305 | Timm23 | Rat | nitrates | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of TIMM23 more ... | CTD | PMID:35964746 | Timm23 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of TIMM23 mRNA | CTD | PMID:32680482 | Timm23 | Rat | perfluorooctanoic acid | increases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of TIMM23 protein | CTD | PMID:26879310 | Timm23 | Rat | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of TIMM23 mRNA | CTD | PMID:12082028 | Timm23 | Rat | piroxicam | increases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Piroxicam results in increased expression of TIMM23 mRNA | CTD | PMID:21858171 | Timm23 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of TIMM23 mRNA | CTD | PMID:30047161 | Timm23 | Rat | rac-lactic acid | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TIMM23 mRNA | CTD | PMID:30851411 | Timm23 | Rat | resveratrol | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | resveratrol results in decreased expression of TIMM23 protein | CTD | PMID:18089832 | Timm23 | Rat | resveratrol | multiple interactions | ISO | TIMM23 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TIMM23 mRNA | CTD | PMID:23557933 | Timm23 | Rat | sodium arsenite | increases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TIMM23 mRNA | CTD | PMID:28595984|PMID:34032870 | Timm23 | Rat | tamoxifen | affects expression | ISO | Timm23 (Mus musculus) | 6480464 | Tamoxifen affects the expression of TIMM23 mRNA | CTD | PMID:17555576 | Timm23 | Rat | thapsigargin | decreases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of TIMM23 mRNA | CTD | PMID:22378314 | Timm23 | Rat | triptonide | increases expression | ISO | Timm23 (Mus musculus) | 6480464 | triptonide results in increased expression of TIMM23 mRNA | CTD | PMID:33045310 | Timm23 | Rat | valproic acid | increases expression | ISO | TIMM23 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TIMM23 mRNA | CTD | PMID:23179753 | Timm23 | Rat | zidovudine | multiple interactions | ISO | Timm23 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA | CTD | PMID:18313992 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















