Timm17a (translocase of inner mitochondrial membrane 17A) - Rat Genome Database

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Gene: Timm17a (translocase of inner mitochondrial membrane 17A) Rattus norvegicus
Analyze
Symbol: Timm17a
Name: translocase of inner mitochondrial membrane 17A
RGD ID: 3862
Description: Predicted to contribute to protein transmembrane transporter activity. Involved in positive regulation of protein processing. Located in mitochondrial inner membrane. Orthologous to human TIMM17A (translocase of inner mitochondrial membrane 17A); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inner membrane preprotein translocase Tim17a; MGC72274; mitochondrial import inner membrane translocase subunit Tim17-A; Tim17; Timm17; translocase of inner mitochondrial membrane 17 homolog A; translocase of inner mitochondrial membrane 17 homolog A (yeast); translocator of inner mitochondrial membrane 17 kDa; translocator of inner mitochondrial membrane 17 kDa a; translocator of inner mitochondrial membrane 17 kDa, a; translocator of inner mitochondrial membrane 17a; translocator of inner mitochondrial membrane 17a (yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Timm17al1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,282,918 - 49,296,363 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1349,282,918 - 49,307,904 (-)EnsemblGRCr8
mRatBN7.21346,731,117 - 46,742,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,730,660 - 46,742,655 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1349,337,908 - 49,349,396 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,625,983 - 50,637,472 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,890,625 - 47,902,136 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,124,641 - 52,136,127 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,124,635 - 52,136,127 (-)Ensemblrn6Rnor6.0
Rnor_5.01357,174,172 - 57,185,658 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41348,297,516 - 48,309,303 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1347,051,694 - 47,063,180 (-)NCBICelera
RGSC_v3.11348,311,558 - 48,323,346 (-)NCBI
Cytogenetic Map13q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,10-phenanthroline  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
ATP  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
glafenine  (EXP)
hydrogen peroxide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
mifepristone  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
nobiletin  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
phenol  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes. Hinojos CA, etal., Hypertension 2005 Apr;45(4):698-704. Epub 2005 Feb 14.
4. Identification of the protein import components of the rat mitochondrial inner membrane, rTIM17, rTIM23, and rTIM44. Ishihara N and Mihara K, J Biochem (Tokyo) 1998 Apr;123(4):722-32.
5. Characterization of the initial steps of precursor import into rat liver mitoplasts. Ishihara N, etal., J Biochem. 1998 Oct;124(4):824-34.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Unlocking the presequence import pathway. Schulz C, etal., Trends Cell Biol. 2015 May;25(5):265-75. doi: 10.1016/j.tcb.2014.12.001. Epub 2014 Dec 23.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
13. Cooperation of protein machineries in mitochondrial protein sorting. Wenz LS, etal., Biochim Biophys Acta. 2015 May;1853(5):1119-29. doi: 10.1016/j.bbamcr.2015.01.012. Epub 2015 Jan 26.
Additional References at PubMed
PMID:10339406   PMID:12477932   PMID:14651853   PMID:18614015   PMID:20053669  


Genomics

Comparative Map Data
Timm17a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,282,918 - 49,296,363 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1349,282,918 - 49,307,904 (-)EnsemblGRCr8
mRatBN7.21346,731,117 - 46,742,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,730,660 - 46,742,655 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1349,337,908 - 49,349,396 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,625,983 - 50,637,472 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,890,625 - 47,902,136 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,124,641 - 52,136,127 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,124,635 - 52,136,127 (-)Ensemblrn6Rnor6.0
Rnor_5.01357,174,172 - 57,185,658 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41348,297,516 - 48,309,303 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1347,051,694 - 47,063,180 (-)NCBICelera
RGSC_v3.11348,311,558 - 48,323,346 (-)NCBI
Cytogenetic Map13q13NCBI
TIMM17A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381201,955,503 - 201,970,664 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1201,955,476 - 201,970,664 (+)Ensemblhg38GRCh38
GRCh371201,924,631 - 201,939,792 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,191,271 - 200,206,412 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341198,656,304 - 198,671,444NCBI
Celera1175,048,350 - 175,063,536 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,090,472 - 173,105,672 (+)NCBIHuRef
CHM1_11203,346,842 - 203,362,018 (+)NCBICHM1_1
T2T-CHM13v2.01201,213,194 - 201,228,387 (+)NCBIT2T-CHM13v2.0
Timm17a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,229,273 - 135,241,475 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,222,951 - 135,241,516 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381135,301,535 - 135,313,737 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,295,213 - 135,313,778 (-)Ensemblmm10GRCm38
MGSCv371137,198,112 - 137,210,314 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361137,117,946 - 137,130,148 (-)NCBIMGSCv36mm8
Celera1137,926,600 - 137,940,154 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.48NCBI
Timm17a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,020,850 - 38,031,651 (+)Ensembl
ChiLan1.0NW_00495540638,020,886 - 38,031,651 (+)NCBIChiLan1.0ChiLan1.0
TIMM17A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2147,412,600 - 47,427,100 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1147,377,315 - 47,391,712 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,552,399 - 177,567,148 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,854,424 - 181,868,960 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1181,854,412 - 181,868,960 (+)EnsemblpanPan2panpan1.1
TIMM17A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.171,002,710 - 1,015,803 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl71,003,236 - 1,015,694 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha71,054,363 - 1,067,437 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.071,010,536 - 1,023,620 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl71,010,178 - 1,023,535 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17998,561 - 1,011,620 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.071,106,754 - 1,119,814 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.071,130,770 - 1,143,830 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Timm17a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934473,301,779 - 73,313,520 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365672,537,236 - 2,548,070 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365672,536,454 - 2,548,138 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIMM17A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,200,368 - 24,211,786 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11024,200,345 - 24,211,790 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TIMM17A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12527,436,066 - 27,450,512 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605528,218,698 - 28,232,886 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Timm17a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,814,582 - 8,826,622 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248078,814,584 - 8,826,649 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Timm17a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v110408,089 - 419,875 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Timm17a
98 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:153
Count of miRNA genes:118
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000009398
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134627292251216694Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134599007750392939Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134778041850392939Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
D13Hmgc62  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,740,002 - 46,740,211 (+)MAPPERmRatBN7.2
Rnor_6.01352,133,526 - 52,133,734NCBIRnor6.0
Rnor_5.01357,183,057 - 57,183,265UniSTSRnor5.0
RGSC_v3.41348,306,701 - 48,306,909UniSTSRGSC3.4
Celera1347,060,579 - 47,060,787UniSTS
Cytogenetic Map13q13UniSTS
RH127788  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,731,205 - 46,731,389 (+)MAPPERmRatBN7.2
Rnor_6.01352,124,730 - 52,124,913NCBIRnor6.0
Rnor_5.01357,174,261 - 57,174,444UniSTSRnor5.0
RGSC_v3.41348,297,605 - 48,297,788UniSTSRGSC3.4
Celera1347,051,783 - 47,051,966UniSTS
RH 3.4 Map10194.1UniSTS
Cytogenetic Map13q13UniSTS
RH136499  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2679,637,593 - 79,637,802 (+)MAPPERmRatBN7.2
mRatBN7.21346,731,287 - 46,731,496 (+)MAPPERmRatBN7.2
Rnor_6.01352,124,812 - 52,125,020NCBIRnor6.0
Rnor_6.0683,252,719 - 83,252,927NCBIRnor6.0
Rnor_5.01357,174,343 - 57,174,551UniSTSRnor5.0
Rnor_5.0692,772,158 - 92,772,366UniSTSRnor5.0
RGSC_v3.4682,484,770 - 82,484,978UniSTSRGSC3.4
RGSC_v3.41348,297,687 - 48,297,895UniSTSRGSC3.4
Celera1347,051,865 - 47,052,073UniSTS
Celera678,292,310 - 78,292,518UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map6q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009398   ⟹   ENSRNOP00000009398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,282,918 - 49,294,404 (-)Ensembl
mRatBN7.2 Ensembl1346,731,127 - 46,742,623 (-)Ensembl
Rnor_6.0 Ensembl1352,124,635 - 52,136,127 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099219   ⟹   ENSRNOP00000094804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,282,918 - 49,307,904 (-)Ensembl
mRatBN7.2 Ensembl1346,730,660 - 46,742,655 (-)Ensembl
RefSeq Acc Id: NM_019351   ⟹   NP_062224
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81349,282,918 - 49,294,404 (-)NCBI
mRatBN7.21346,731,117 - 46,742,604 (-)NCBI
Rnor_6.01352,124,641 - 52,136,127 (-)NCBI
Rnor_5.01357,174,172 - 57,185,658 (-)NCBI
RGSC_v3.41348,297,516 - 48,309,303 (-)RGD
Celera1347,051,694 - 47,063,180 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272562   ⟹   XP_063128632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81349,282,925 - 49,296,363 (-)NCBI
Protein Sequences
Protein RefSeqs NP_062224 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128632 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH61982 (Get FASTA)   NCBI Sequence Viewer  
  BAA21818 (Get FASTA)   NCBI Sequence Viewer  
  EDM09699 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009398
GenBank Protein O35092 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062224   ⟸   NM_019351
- UniProtKB: O35092 (UniProtKB/Swiss-Prot),   A6ICE7 (UniProtKB/TrEMBL),   A0A8I6ANA6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009398   ⟸   ENSRNOT00000009398
Ensembl Acc Id: ENSRNOP00000094804   ⟸   ENSRNOT00000099219
RefSeq Acc Id: XP_063128632   ⟸   XM_063272562
- Peptide Label: isoform X1
- UniProtKB: O35092 (UniProtKB/Swiss-Prot),   A6ICE7 (UniProtKB/TrEMBL),   A0A8I6ANA6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35092-F1-model_v2 AlphaFold O35092 1-171 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698842
Promoter ID:EPDNEW_R9366
Type:multiple initiation site
Name:Timm17a_1
Description:translocase of inner mitochondrial membrane 17A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01352,136,141 - 52,136,201EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3862 AgrOrtholog
BioCyc Gene G2FUF-18211 BioCyc
Ensembl Genes ENSRNOG00000007040 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000009398 ENTREZGENE
IMAGE_CLONE IMAGE:5598788 IMAGE-MGC_LOAD
InterPro Tim17 UniProtKB/Swiss-Prot
KEGG Report rno:54311 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72274 IMAGE-MGC_LOAD
NCBI Gene 54311 ENTREZGENE
PANTHER MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 UniProtKB/Swiss-Prot
  MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A UniProtKB/Swiss-Prot
Pfam Tim17 UniProtKB/Swiss-Prot
PhenoGen Timm17a PhenoGen
RatGTEx ENSRNOG00000007040 RatGTEx
TIGR TC228848
UniProt A0A8I6ANA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q460_RAT UniProtKB/TrEMBL
  A6ICE7 ENTREZGENE, UniProtKB/TrEMBL
  O35092 ENTREZGENE
  Q6P6W9_RAT UniProtKB/TrEMBL
  TI17A_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-01 Timm17a  translocase of inner mitochondrial membrane 17A  Timm17a  translocase of inner mitochondrial membrane 17 homolog A (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Timm17a  translocase of inner mitochondrial membrane 17 homolog A (yeast)  Timm17a  translocase of inner mitochondrial membrane 17a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Timm17a  translocase of inner mitochondrial membrane 17a  Timm17a  translocator of inner mitochondrial membrane 17a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Timm17a  translocator of inner mitochondrial membrane 17a    translocator of inner mitochondrial membrane 17a (yeast)  Name updated 1299863 APPROVED
2002-06-10 Timm17a  translocator of inner mitochondrial membrane 17a (yeast)      Name updated 70584 APPROVED
2001-12-06 Timm17a  translocator of inner mitochondrial membrane 17 kDa, a      Symbol updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression is decreased 1.3 fold in SHR compared with WKY rats 1357414