Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rgs6 | Rat | 1,2-dichloroethane | increases expression | ISO | Rgs6 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of RGS6 mRNA | CTD | PMID:28960355 | Rgs6 | Rat | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of RGS6 mRNA | CTD | PMID:30723492 | Rgs6 | Rat | 2,2',5,5'-tetrachlorobiphenyl | increases expression | EXP | | 6480464 | 2,5,2',5'-tetrachlorobiphenyl results in increased expression of RGS6 mRNA | CTD | PMID:23829299 | Rgs6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RGS6 mRNA | CTD | PMID:32109520 | Rgs6 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of RGS6 mRNA | CTD | PMID:32109520 | Rgs6 | Rat | 2-palmitoylglycerol | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of RGS6 mRNA | CTD | PMID:37199045 | Rgs6 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of RGS6 mRNA | CTD | PMID:25825206 | Rgs6 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RGS6 mRNA | CTD | PMID:24780913 | Rgs6 | Rat | aflatoxin B1 | decreases methylation | ISO | RGS6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of RGS6 gene | CTD | PMID:27153756 | Rgs6 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | RGS6 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of RGS6 intron | CTD | PMID:30157460 | Rgs6 | Rat | amiodarone | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of RGS6 mRNA | CTD | PMID:19774075 | Rgs6 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RGS6 mRNA | CTD | PMID:16483693 | Rgs6 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of RGS6 gene | CTD | PMID:35440735 | Rgs6 | Rat | benzo[a]pyrene | decreases expression | ISO | Rgs6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of RGS6 mRNA | CTD | PMID:22228805 | Rgs6 | Rat | benzo[a]pyrene | affects methylation | ISO | RGS6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RGS6 3' UTR; Benzo(a)pyrene affects the methylation of RGS6 intron; more ... | CTD | PMID:27901495|PMID:30157460 | Rgs6 | Rat | benzo[a]pyrene | increases methylation | ISO | RGS6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RGS6 5' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Rgs6 | Rat | benzo[e]pyrene | increases methylation | ISO | RGS6 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of RGS6 intron | CTD | PMID:30157460 | Rgs6 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RGS6 mRNA | CTD | PMID:25181051 | Rgs6 | Rat | bisphenol A | multiple interactions | ISO | RGS6 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of RGS6 gene | CTD | PMID:31601247 | Rgs6 | Rat | bisphenol A | affects methylation | ISO | RGS6 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of RGS6 gene | CTD | PMID:31601247 | Rgs6 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RGS6 mRNA | CTD | PMID:30816183|PMID:34947998 | Rgs6 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of RGS6 mRNA | CTD | PMID:33453195 | Rgs6 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of RGS6 mRNA | CTD | PMID:27523638 | Rgs6 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of RGS6 mRNA | CTD | PMID:26577399 | Rgs6 | Rat | doxorubicin | decreases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RGS6 mRNA | CTD | PMID:29803840|PMID:30031762 | Rgs6 | Rat | doxorubicin | decreases expression | ISO | Rgs6 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of RGS6 mRNA | CTD | PMID:39631538 | Rgs6 | Rat | fulvestrant | multiple interactions | ISO | RGS6 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of RGS6 gene | CTD | PMID:31601247 | Rgs6 | Rat | genistein | decreases expression | ISO | Rgs6 (Mus musculus) | 6480464 | Genistein results in decreased expression of RGS6 mRNA | CTD | PMID:32186404 | Rgs6 | Rat | lead(0) | affects expression | ISO | RGS6 (Homo sapiens) | 6480464 | Lead affects the expression of RGS6 mRNA | CTD | PMID:28903495 | Rgs6 | Rat | manganese atom | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Manganese results in increased expression of RGS6 mRNA | CTD | PMID:17175027 | Rgs6 | Rat | manganese(0) | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Manganese results in increased expression of RGS6 mRNA | CTD | PMID:17175027 | Rgs6 | Rat | manganese(II) chloride | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | manganese chloride results in increased expression of RGS6 mRNA | CTD | PMID:17175027 | Rgs6 | Rat | methapyrilene | increases methylation | ISO | RGS6 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of RGS6 intron | CTD | PMID:30157460 | Rgs6 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of RGS6 gene | CTD | PMID:35440735 | Rgs6 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Rgs6 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of RGS6 mRNA | CTD | PMID:22401849 | Rgs6 | Rat | morphine | increases expression | ISO | Rgs6 (Mus musculus) | 6480464 | Morphine results in increased expression of RGS6 mRNA | CTD | PMID:21178816 | Rgs6 | Rat | morphine | decreases expression | ISO | Rgs6 (Mus musculus) | 597830059 | morphine decreases expression of Rgs6 mRNA in central gray substance of midbrain | RGD | | Rgs6 | Rat | morphine | multiple interactions | ISO | Rgs6 (Mus musculus) | 597830059 | naloxone cotreated with morphine decreases expression of Rgs6 mRNA in central gray substance of midbrain more ... | RGD | | Rgs6 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of RGS6 gene | CTD | PMID:33148267 | Rgs6 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RGS6 mRNA | CTD | PMID:20360939 | Rgs6 | Rat | nickel atom | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Nickel results in increased expression of RGS6 mRNA | CTD | PMID:23195993 | Rgs6 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of RGS6 mRNA | CTD | PMID:32680482 | Rgs6 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in increased expression of RGS6 mRNA | CTD | PMID:25812627 | Rgs6 | Rat | perfluorononanoic acid | increases expression | ISO | RGS6 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of RGS6 mRNA | CTD | PMID:25812627 | Rgs6 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of RGS6 gene | CTD | PMID:33148267 | Rgs6 | Rat | phenethyl caffeate | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RGS6 mRNA | CTD | PMID:20360939 | Rgs6 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of RGS6 mRNA | CTD | PMID:28374803 | Rgs6 | Rat | sodium arsenite | affects methylation | ISO | RGS6 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of RGS6 gene | CTD | PMID:28589171 | Rgs6 | Rat | sodium arsenite | increases expression | ISO | Rgs6 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of RGS6 mRNA | CTD | PMID:37682722 | Rgs6 | Rat | sunitinib | decreases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of RGS6 mRNA | CTD | PMID:31533062 | Rgs6 | Rat | titanium dioxide | decreases methylation | ISO | Rgs6 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of RGS6 gene | CTD | PMID:35295148 | Rgs6 | Rat | titanium dioxide | increases methylation | ISO | Rgs6 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of RGS6 gene | CTD | PMID:35295148 | Rgs6 | Rat | triclosan | decreases expression | ISO | RGS6 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of RGS6 mRNA | CTD | PMID:30510588 | Rgs6 | Rat | triphenyl phosphate | affects expression | ISO | RGS6 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RGS6 mRNA | CTD | PMID:37042841 | Rgs6 | Rat | zidovudine | multiple interactions | ISO | RGS6 (Homo sapiens) | 6480464 | [Zidovudine co-treated with IFNA1 protein] results in increased expression of RGS6 mRNA | CTD | PMID:20370541 | | 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