Rgs6 (regulator of G-protein signaling 6) - Rat Genome Database

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Gene: Rgs6 (regulator of G-protein signaling 6) Rattus norvegicus
Analyze
Symbol: Rgs6
Name: regulator of G-protein signaling 6
RGD ID: 3569
Description: Enables protein domain specific binding activity. Involved in positive regulation of neuron differentiation. Part of protein-containing complex. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human RGS6 (regulator of G protein signaling 6); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86107,875,883 - 108,527,472 (+)NCBIGRCr8
mRatBN7.26102,264,451 - 102,796,311 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6102,264,447 - 102,824,753 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6102,420,755 - 102,953,980 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06102,719,975 - 103,253,217 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06102,089,444 - 102,622,685 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06106,310,442 - 106,598,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6106,496,992 - 106,602,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06114,636,387 - 114,736,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46106,470,420 - 106,964,581 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16106,940,142 - 106,967,896 (+)NCBI
Celera6100,100,895 - 100,625,650 (+)NCBICelera
Cytogenetic Map6q24-q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rgs6Ratalcohol dependence  ISORGS6 (Homo sapiens)405650603associated with other drug dependencies and DNA:SNPs:CDS: (rs11621871)RGD 
Rgs6Ratmorphine dependence treatmentISORgs6 (Mus musculus)597830059 RGD 

1 to 20 of 54 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rgs6Rat1,2-dichloroethane increases expressionISORgs6 (Mus musculus)6480464ethylene dichloride results in increased expression of RGS6 mRNACTDPMID:28960355
Rgs6Rat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of RGS6 mRNACTDPMID:30723492
Rgs6Rat2,2',5,5'-tetrachlorobiphenyl increases expressionEXP 64804642 more ...CTDPMID:23829299
Rgs6Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of RGS6 mRNACTDPMID:32109520
Rgs6Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Rgs6Rat2-palmitoylglycerol increases expressionISORGS6 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of RGS6 mRNACTDPMID:37199045
Rgs6Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of RGS6 mRNACTDPMID:25825206
Rgs6Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of RGS6 mRNACTDPMID:24780913
Rgs6Rataflatoxin B1 decreases methylationISORGS6 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of RGS6 geneCTDPMID:27153756
Rgs6RatAflatoxin B2 alpha increases methylationISORGS6 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of RGS6 intronCTDPMID:30157460
Rgs6Ratamiodarone increases expressionISORGS6 (Homo sapiens)6480464Amiodarone results in increased expression of RGS6 mRNACTDPMID:19774075
Rgs6Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of RGS6 mRNACTDPMID:16483693
Rgs6Ratatrazine affects methylationEXP 6480464Atrazine affects the methylation of RGS6 geneCTDPMID:35440735
Rgs6Ratbenzo[a]pyrene decreases expressionISORgs6 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of RGS6 mRNACTDPMID:22228805
Rgs6Ratbenzo[a]pyrene affects methylationISORGS6 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of RGS6 3' UTR more ...CTDPMID:27901495 and PMID:30157460
Rgs6Ratbenzo[a]pyrene increases methylationISORGS6 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of RGS6 5' UTR and Benzo(a)pyrene results in increased methylation of RGS6 promoterCTDPMID:27901495
Rgs6Ratbenzo[e]pyrene increases methylationISORGS6 (Homo sapiens)6480464benzo(e)pyrene results in increased methylation of RGS6 intronCTDPMID:30157460
Rgs6Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of RGS6 mRNACTDPMID:25181051
Rgs6Ratbisphenol A multiple interactionsISORGS6 (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in increased methylation of RGS6 geneCTDPMID:31601247
Rgs6Ratbisphenol A affects methylationISORGS6 (Homo sapiens)6480464bisphenol A affects the methylation of RGS6 geneCTDPMID:31601247

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rgs6RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR0362841600115GO_REF:0000002InterProGO_REF:0000002
Rgs6RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR015898 and InterPro:IPR0362841600115GO_REF:0000002InterProGO_REF:0000002
Rgs6Ratintracellular signal transduction involved_inIEAInterPro:IPR0005911600115GO_REF:0000002InterProGO_REF:0000002
Rgs6Ratnegative regulation of signal transduction involved_inIEAUniProtKB-KW:KW-07341600115GO_REF:0000043UniProtGO_REF:0000043
Rgs6Ratpositive regulation of GTPase activity involved_inISSUniProtKB:P497581600115GO_REF:0000024UniProtGO_REF:0000024
Rgs6Ratpositive regulation of GTPase activity involved_inISORGS6 (Homo sapiens)1624291 PMID:10521509RGDPMID:10521509
Rgs6Ratpositive regulation of neuron differentiation  IDA 737642 RGD 
Rgs6Ratregulation of G protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR0470161600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rgs6Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Rgs6Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rgs6Ratcytosol located_inIEAUniProtKB:P49758 and ensembl:ENSP000004510301600115GO_REF:0000107EnsemblGO_REF:0000107
Rgs6Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Rgs6Ratcytosol located_inISORGS6 (Homo sapiens)1624291 PMID:10521509RGDPMID:10521509
Rgs6Ratcytosol located_inISSUniProtKB:P497581600115GO_REF:0000024UniProtGO_REF:0000024
Rgs6Ratmembrane located_inISORGS6 (Homo sapiens)1624291 PMID:10521509RGDPMID:10521509
Rgs6Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Rgs6Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Rgs6Ratmembrane located_inIEAUniProtKB:P49758 and ensembl:ENSP000004510301600115GO_REF:0000107EnsemblGO_REF:0000107
Rgs6Ratmembrane located_inISSUniProtKB:P497581600115GO_REF:0000024UniProtGO_REF:0000024
Rgs6Ratnucleolus located_inISORGS6 (Homo sapiens)1624291 RGDGO_REF:0000052
Rgs6Ratnucleoplasm located_inISORGS6 (Homo sapiens)1624291 RGDGO_REF:0000052
Rgs6Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Rgs6Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Rgs6Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Rgs6Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Rgs6Ratprotein-containing complex  IDA 737642 RGD 
1 to 18 of 18 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rgs6Ratacetylcholine signaling pathway via muscarinic acetylcholine receptor   ISORgs6 (Mus musculus)8549594 RGD 

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#
Reference Title
Reference Citation
1. An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count. Chen G, etal., Addict Biol. 2017 Nov;22(6):1475-1485. doi: 10.1111/adb.12402. Epub 2016 May 5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. Gold SJ, etal., J Neurosci 1997 Oct 15;17(20):8024-37.
5. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Koelle MR and Horvitz HR, Cell 1996 Jan 12;84(1):115-25.
6. RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6. Liu Z, etal., J Biol Chem 2002 Oct 4;277(40):37832-9. Epub 2002 Jul 24.
7. Expression of neural RGS-R7 and Gbeta5 Proteins in Response to Acute and Chronic Morphine. López-Fando A, etal., Neuropsychopharmacology. 2005 Jan;30(1):99-110. doi: 10.1038/sj.npp.1300515.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. RGS Proteins in Heart: Brakes on the Vagus. Stewart A, etal., Front Physiol. 2012 Apr 13;3:95. doi: 10.3389/fphys.2012.00095. eCollection 2012.
1 to 13 of 13 rows
PMID:10521509  



Rgs6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86107,875,883 - 108,527,472 (+)NCBIGRCr8
mRatBN7.26102,264,451 - 102,796,311 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6102,264,447 - 102,824,753 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6102,420,755 - 102,953,980 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06102,719,975 - 103,253,217 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06102,089,444 - 102,622,685 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06106,310,442 - 106,598,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6106,496,992 - 106,602,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06114,636,387 - 114,736,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46106,470,420 - 106,964,581 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16106,940,142 - 106,967,896 (+)NCBI
Celera6100,100,895 - 100,625,650 (+)NCBICelera
Cytogenetic Map6q24-q31NCBI
RGS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381471,867,335 - 72,630,029 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1471,932,429 - 72,566,530 (+)EnsemblGRCh38hg38GRCh38
GRCh371472,398,888 - 73,033,238 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361471,469,539 - 72,102,991 (+)NCBINCBI36Build 36hg18NCBI36
Build 341471,469,585 - 72,100,407NCBI
Celera1452,462,976 - 53,096,417 (+)NCBICelera
Cytogenetic Map14q24.2NCBI
HuRef1452,565,478 - 53,199,765 (+)NCBIHuRef
CHM1_11472,336,952 - 72,971,253 (+)NCBICHM1_1
T2T-CHM13v2.01466,072,765 - 66,835,660 (+)NCBIT2T-CHM13v2.0
Rgs6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391282,663,325 - 83,208,835 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1282,635,066 - 83,208,830 (+)EnsemblGRCm39 Ensembl
GRCm381282,616,551 - 83,162,061 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1282,588,292 - 83,162,056 (+)EnsemblGRCm38mm10GRCm38
MGSCv371283,718,025 - 84,259,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361283,535,886 - 84,077,669 (+)NCBIMGSCv36mm8
Celera1284,069,722 - 84,604,177 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1238.14NCBI
Rgs6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555232,762,987 - 3,335,474 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555232,763,143 - 3,366,851 (-)NCBIChiLan1.0ChiLan1.0
RGS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21573,042,379 - 73,677,406 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11472,258,892 - 72,893,920 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01452,511,846 - 53,146,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11471,377,567 - 72,012,766 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1471,409,701 - 72,008,988 (+)Ensemblpanpan1.1panPan2
RGS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1845,392,246 - 45,975,073 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl845,438,239 - 46,009,049 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha845,077,684 - 45,656,669 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0845,630,187 - 46,197,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl845,654,256 - 46,194,458 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1845,301,232 - 45,866,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0845,329,999 - 45,882,332 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0845,692,998 - 46,272,644 (+)NCBIUU_Cfam_GSD_1.0
Rgs6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864030,144,323 - 30,732,878 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364881,361,310 - 1,921,353 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364881,336,075 - 1,924,635 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl795,365,939 - 95,930,034 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1795,365,212 - 95,930,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RGS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12449,161,466 - 49,803,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2449,591,815 - 49,775,653 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605337,367,918 - 37,991,218 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473428,829,698 - 29,411,779 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473428,830,254 - 29,436,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rgs6
3311 total Variants

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:56
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000058181
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat

1 to 10 of 35 rows
RH140792  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,792,686 - 102,792,927 (+)MAPPERmRatBN7.2
Rnor_6.06106,598,200 - 106,598,440NCBIRnor6.0
Rnor_5.06114,736,322 - 114,736,562UniSTSRnor5.0
RGSC_v3.46106,987,770 - 106,988,010UniSTSRGSC3.4
Celera6100,625,182 - 100,625,422UniSTS
RH 3.4 Map6732.5UniSTS
Cytogenetic Map6q24UniSTS
RH143195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,792,822 - 102,793,075 (+)MAPPERmRatBN7.2
Rnor_6.06106,598,336 - 106,598,588NCBIRnor6.0
Rnor_5.06114,736,458 - 114,736,710UniSTSRnor5.0
RGSC_v3.46106,987,906 - 106,988,158UniSTSRGSC3.4
Celera6100,625,318 - 100,625,570UniSTS
RH 3.4 Map6738.0UniSTS
Cytogenetic Map6q24UniSTS
RH143409  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr86108,423,622 - 108,423,874 (+)Marker Load Pipeline
mRatBN7.26102,692,460 - 102,692,712 (+)MAPPERmRatBN7.2
Rnor_6.06106,499,816 - 106,500,067NCBIRnor6.0
Rnor_5.06114,639,079 - 114,639,330UniSTSRnor5.0
RGSC_v3.46106,876,517 - 106,876,768UniSTSRGSC3.4
Celera6100,526,473 - 100,526,724UniSTS
RH 3.4 Map6738.0UniSTS
Cytogenetic Map6q24UniSTS
BF398997  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,773,210 - 102,773,402 (+)MAPPERmRatBN7.2
Rnor_6.06106,578,724 - 106,578,915NCBIRnor6.0
Rnor_5.06114,716,846 - 114,717,037UniSTSRnor5.0
RGSC_v3.46106,968,294 - 106,968,485UniSTSRGSC3.4
Celera6100,605,596 - 100,605,787UniSTS
RH 3.4 Map6738.0UniSTS
Cytogenetic Map6q24UniSTS
fc10a03.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,616,986 - 102,618,290 (+)MAPPERmRatBN7.2
Rnor_6.06107,944,860 - 107,946,163NCBIRnor6.0
Rnor_5.06117,600,272 - 117,601,576NCBIRnor5.0
RGSC_v3.46106,800,999 - 106,802,302UniSTSRGSC3.4
Celera6100,451,085 - 100,452,388UniSTS
Cytogenetic Map6q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000058181   ⟹   ENSRNOP00000054984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,155 (+)Ensembl
Rnor_6.0 Ensembl6106,497,125 - 106,598,668 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086136   ⟹   ENSRNOP00000069089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,693,478 - 102,773,706 (+)Ensembl
Rnor_6.0 Ensembl6106,496,992 - 106,602,139 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095987   ⟹   ENSRNOP00000082201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,631 - 102,824,753 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100420   ⟹   ENSRNOP00000077898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,733,221 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103061   ⟹   ENSRNOP00000079796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,689,770 - 102,770,177 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107970   ⟹   ENSRNOP00000091378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,773,304 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109319   ⟹   ENSRNOP00000079945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112595   ⟹   ENSRNOP00000092991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113156   ⟹   ENSRNOP00000091512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114544   ⟹   ENSRNOP00000085795
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,824,753 (+)Ensembl
RefSeq Acc Id: NM_019342   ⟹   NP_062215
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,996,495 - 108,524,316 (+)NCBI
mRatBN7.26102,265,295 - 102,793,155 (+)NCBI
Rnor_6.06106,310,442 - 106,598,668 (+)NCBI
Rnor_5.06114,636,387 - 114,736,790 (+)NCBI
Celera6100,100,895 - 100,625,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112783   ⟹   XP_038968711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,996,666 - 108,527,472 (+)NCBI
mRatBN7.26102,265,483 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112784   ⟹   XP_038968712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,996,881 - 108,527,472 (+)NCBI
mRatBN7.26102,265,679 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112785   ⟹   XP_038968713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,996,460 - 108,527,472 (+)NCBI
mRatBN7.26102,265,264 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112787   ⟹   XP_038968715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,504,530 (+)NCBI
mRatBN7.26102,293,910 - 102,777,665 (+)NCBI
RefSeq Acc Id: XM_039112789   ⟹   XP_038968717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,523,530 (+)NCBI
mRatBN7.26102,293,910 - 102,792,406 (+)NCBI
RefSeq Acc Id: XM_039112790   ⟹   XP_038968718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,488,421 (+)NCBI
mRatBN7.26102,293,910 - 102,759,765 (+)NCBI
RefSeq Acc Id: XM_063262367   ⟹   XP_063118437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,527,472 (+)NCBI
RefSeq Acc Id: XM_063262368   ⟹   XP_063118438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,527,472 (+)NCBI
RefSeq Acc Id: XM_063262369   ⟹   XP_063118439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,527,472 (+)NCBI
RefSeq Acc Id: XM_063262370   ⟹   XP_063118440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,996,608 - 108,527,472 (+)NCBI
RefSeq Acc Id: XR_005505572
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86107,875,883 - 108,523,504 (+)NCBI
mRatBN7.26102,293,910 - 102,792,343 (+)NCBI
1 to 5 of 21 rows
1 to 5 of 21 rows
RefSeq Acc Id: NP_062215   ⟸   NM_019342
- UniProtKB: F1LS67 (UniProtKB/TrEMBL),   A0A8I6GJP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054984   ⟸   ENSRNOT00000058181
Ensembl Acc Id: ENSRNOP00000069089   ⟸   ENSRNOT00000086136
RefSeq Acc Id: XP_038968713   ⟸   XM_039112785
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL),   A0A8I6GJP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968711   ⟸   XM_039112783
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL),   A0A8I6GJP9 (UniProtKB/TrEMBL)
DEP   RGS

Name Modeler Protein Id AA Range Protein Structure
AF-P49801-F1-model_v2 AlphaFold P49801 1-66 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-36866 BioCyc
Ensembl Genes ENSRNOG00000008082 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000058181 ENTREZGENE
  ENSRNOT00000086136 ENTREZGENE
  ENSRNOT00000107970 ENTREZGENE
  ENSRNOT00000109319 ENTREZGENE
  ENSRNOT00000113156 ENTREZGENE
  ENSRNOT00000114544 ENTREZGENE
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot
InterPro RGS UniProtKB/Swiss-Prot
  RGS6/7/9/11 UniProtKB/Swiss-Prot
  RGS_sf UniProtKB/Swiss-Prot
  RGS_subdomain_2 UniProtKB/Swiss-Prot
NCBI Gene 54295 ENTREZGENE
PANTHER LP21163P UniProtKB/Swiss-Prot
  REGULATOR OF G-PROTEIN SIGNALING 6 UniProtKB/Swiss-Prot
Pfam RGS UniProtKB/Swiss-Prot
PhenoGen Rgs6 PhenoGen
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot
PROSITE RGS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008082 RatGTEx
Superfamily-SCOP SSF48097 UniProtKB/Swiss-Prot
UniProt A0A0G2JUG4_RAT UniProtKB/TrEMBL
  A0A8I5YC31_RAT UniProtKB/TrEMBL
  A0A8I5ZPB7_RAT UniProtKB/TrEMBL
  A0A8I5ZTQ5_RAT UniProtKB/TrEMBL
  A0A8I6A357_RAT UniProtKB/TrEMBL
  A0A8I6AIT2_RAT UniProtKB/TrEMBL
  A0A8I6G3X7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJP9 ENTREZGENE, UniProtKB/TrEMBL
  F1LS67 ENTREZGENE, UniProtKB/TrEMBL
  P49801 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Rgs6  regulator of G-protein signaling 6      Name updated 70584 APPROVED

Note Type Note Reference
gene_physical_interaction human homolog binds neuronal growth associated protein SCG10 737642