Symbol:
Ret
Name:
ret proto-oncogene
RGD ID:
3556
Description:
Predicted to enable calcium ion binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including innervation; positive regulation of neuron maturation; and retina development in camera-type eye. Located in several cellular components, including dendrite; early endosome; and neuronal cell body. Biomarker of Parkinsonism; brain ischemia; and pheochromocytoma. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; familial medullary thyroid carcinoma; multiple endocrine neoplasia type 2A; multiple endocrine neoplasia type 2B; and pheochromocytoma. Orthologous to human RET (ret proto-oncogene); PARTICIPATES IN endocytosis pathway; thyroid cancer pathway; INTERACTS WITH (+)-pilocarpine; (-)-anisomycin; 17alpha-ethynylestradiol.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
proto-oncogene tyrosine-protein kinase receptor Ret; receptor tyrosine kinase; Ret gene for receptor tyrosin; Ret proto-oncogene (multiple endocrine neoplasia MEN2A MEN2B and medullary thyroid carcinoma 1 Hirschsprung disease); Ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung disease)
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
RET (ret proto-oncogene)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Ret (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ret (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
RET (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
RET (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ret (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
RET (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
RET (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ret (ret proto-oncogene)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
GSE1 (Gse1 coiled-coil protein)
HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Ret (ret proto-oncogene)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
RET (ret proto-oncogene)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ret (ret proto-oncogene receptor tyrosine kinase)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Ret
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ret
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Candidate Gene For:
Ept5
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 4 152,998,344 - 153,040,556 (-) NCBI GRCr8 mRatBN7.2 4 151,325,969 - 151,368,176 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 4 151,326,431 - 151,368,176 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 4 157,589,266 - 157,631,480 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 4 153,373,235 - 153,415,450 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 4 151,996,254 - 152,038,470 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 4 150,202,170 - 150,249,196 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 4 150,202,058 - 150,244,372 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 4 216,130,142 - 216,177,139 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 4 154,448,179 - 154,491,103 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 4 154,693,019 - 154,735,944 (-) NCBI Celera 4 140,198,457 - 140,240,663 (-) NCBI Celera Cytogenetic Map 4 q42 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ret Rat (+)-pilocarpine multiple interactions EXP 6480464 [Lithium co-treated with Pilocarpine] results in increased expression of RET protein CTD PMID:12914250 Ret Rat (-)-anisomycin decreases expression EXP 6480464 Anisomycin results in decreased expression of RET protein CTD PMID:17555550 Ret Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Ret (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:17555550 Ret Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of RET mRNA CTD PMID:12075121 Ret Rat 17beta-estradiol multiple interactions ISO RET (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RET mRNA more ... CTD PMID:20823114 and PMID:24758408 Ret Rat 17beta-estradiol increases expression ISO RET (Homo sapiens) 6480464 Estradiol results in increased expression of RET mRNA CTD PMID:24758408 more ... Ret Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ret (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 Ret Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ret (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 Ret Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ret (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of RET mRNA CTD PMID:17337447 Ret Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RET mRNA CTD PMID:32109520 Ret Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RET (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of RET mRNA CTD PMID:22903824 Ret Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ret (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of RET mRNA CTD PMID:21570461 Ret Rat 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile affects expression ISO RET (Homo sapiens) 6480464 Verapamil affects the expression of RET protein CTD PMID:12388792 Ret Rat 4,4'-sulfonyldiphenol increases expression ISO Ret (Mus musculus) 6480464 bisphenol S results in increased expression of RET mRNA CTD PMID:30951980 Ret Rat 4-hydroxyphenyl retinamide decreases expression ISO Ret (Mus musculus) 6480464 Fenretinide results in decreased expression of RET mRNA CTD PMID:28973697 Ret Rat 5-azacytidine decreases expression ISO RET (Homo sapiens) 6480464 Azacitidine results in decreased expression of RET mRNA CTD PMID:20823114 Ret Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of RET mRNA and Propylthiouracil results in increased expression of RET protein CTD PMID:22504374 more ... Ret Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of RET mRNA CTD PMID:30047161 Ret Rat afimoxifene multiple interactions ISO RET (Homo sapiens) 6480464 afimoxifene inhibits the reaction [Estrogens results in increased expression of RET mRNA] CTD PMID:21233418 Ret Rat aflatoxin B1 decreases methylation ISO RET (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of RET intron CTD PMID:30157460 Ret Rat aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of RET mRNA CTD PMID:21818840 Ret Rat aldrin multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat all-trans-retinoic acid increases response to substance ISO RET (Homo sapiens) 6480464 RET protein results in increased susceptibility to Tretinoin CTD PMID:16849523 Ret Rat all-trans-retinoic acid decreases expression ISO RET (Homo sapiens) 6480464 Tretinoin results in decreased expression of RET mRNA CTD PMID:33167477 Ret Rat all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of RET mRNA CTD PMID:20488242 Ret Rat all-trans-retinoic acid increases phosphorylation ISO RET (Homo sapiens) 6480464 Tretinoin results in increased phosphorylation of RET protein CTD PMID:17431108 Ret Rat all-trans-retinoic acid multiple interactions ISO RET (Homo sapiens) 6480464 [Tretinoin results in increased secretion of GDNF protein] which results in increased activity of RET protein and Tretinoin results in increased expression of and results in increased phosphorylation of and results in increased activity of RET protein CTD PMID:16849523 Ret Rat all-trans-retinoic acid increases expression ISO RET (Homo sapiens) 6480464 Tretinoin results in increased expression of RET mRNA and Tretinoin results in increased expression of RET protein CTD PMID:16012519 more ... Ret Rat all-trans-retinol multiple interactions EXP 6480464 [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RET protein and [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter] CTD PMID:32526256 Ret Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RET mRNA CTD PMID:35163327 Ret Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of RET mRNA CTD PMID:30047161 Ret Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RET mRNA CTD PMID:16483693 Ret Rat arsane increases activity ISO RET (Homo sapiens) 6480464 Arsenic results in increased activity of RET protein and Arsenic results in increased activity of RET protein alternative form CTD PMID:21195159 Ret Rat arsane multiple interactions ISO RET (Homo sapiens) 6480464 [Arsenic co-treated with RET protein alternative form] results in increased secretion of MMP2 protein alternative form more ... CTD PMID:21195159 Ret Rat arsenic atom multiple interactions ISO RET (Homo sapiens) 6480464 [Arsenic co-treated with RET protein alternative form] results in increased secretion of MMP2 protein alternative form more ... CTD PMID:21195159 Ret Rat arsenic atom increases activity ISO RET (Homo sapiens) 6480464 Arsenic results in increased activity of RET protein and Arsenic results in increased activity of RET protein alternative form CTD PMID:21195159 Ret Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of RET gene CTD PMID:35440735 Ret Rat benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RET mRNA CTD PMID:21839799 Ret Rat benzo[a]pyrene increases methylation ISO RET (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of RET 5' UTR CTD PMID:27901495 Ret Rat benzo[a]pyrene affects methylation ISO RET (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of RET intron and Benzo(a)pyrene affects the methylation of RET promoter CTD PMID:27901495 and PMID:30157460 Ret Rat benzo[a]pyrene decreases expression ISO Ret (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of RET mRNA CTD PMID:22228805 Ret Rat benzo[e]pyrene increases methylation ISO RET (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of RET intron CTD PMID:30157460 Ret Rat bis(2-ethylhexyl) phthalate affects expression ISO Ret (Mus musculus) 6480464 Diethylhexyl Phthalate affects the expression of RET mRNA CTD PMID:37059381 Ret Rat bis(2-ethylhexyl) phthalate decreases expression ISO RET (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of RET mRNA CTD PMID:31163220 Ret Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RET mRNA CTD PMID:12075121 more ... Ret Rat bisphenol A increases expression ISO RET (Homo sapiens) 6480464 bisphenol A results in increased expression of RET mRNA CTD PMID:28711546 Ret Rat bisphenol A increases methylation ISO Ret (Mus musculus) 6480464 bisphenol A results in increased methylation of RET promoter CTD PMID:27312807 Ret Rat bisphenol A increases expression ISO Ret (Mus musculus) 6480464 bisphenol A results in increased expression of RET mRNA CTD PMID:27312807 more ... Ret Rat bisphenol A decreases methylation ISO Ret (Mus musculus) 6480464 bisphenol A results in decreased methylation of RET promoter CTD PMID:27312807 Ret Rat bisphenol F increases expression ISO Ret (Mus musculus) 6480464 bisphenol F results in increased expression of RET mRNA CTD PMID:30951980 Ret Rat bucladesine multiple interactions ISO RET (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RET mRNA CTD PMID:20823114 Ret Rat butanal increases expression ISO RET (Homo sapiens) 6480464 butyraldehyde results in increased expression of RET mRNA CTD PMID:26079696 Ret Rat cadmium dichloride multiple interactions ISO RET (Homo sapiens) 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of RET mRNA CTD PMID:12634122 Ret Rat calcitriol increases expression ISO RET (Homo sapiens) 6480464 Calcitriol results in increased expression of RET mRNA CTD PMID:16002434 Ret Rat camptothecin decreases expression EXP 6480464 Camptothecin results in decreased expression of RET protein CTD PMID:17555550 Ret Rat chlordecone decreases expression ISO Ret (Mus musculus) 6480464 Chlordecone results in decreased expression of RET mRNA CTD PMID:33711761 Ret Rat chlorpyrifos decreases expression ISO Ret (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of RET mRNA CTD PMID:20350560 Ret Rat cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of RET protein CTD PMID:17555550 Ret Rat clomiphene decreases expression ISO RET (Homo sapiens) 6480464 Clomiphene results in decreased expression of RET mRNA CTD PMID:26865669 Ret Rat copper(II) sulfate decreases expression ISO RET (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of RET mRNA CTD PMID:19549813 Ret Rat coumestrol multiple interactions ISO RET (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 Ret Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of RET mRNA CTD PMID:27523638 Ret Rat cycloheximide decreases expression EXP 6480464 Cycloheximide results in decreased expression of RET protein CTD PMID:17555550 Ret Rat D-glucose increases expression EXP 6480464 Glucose results in increased expression of RET mRNA CTD PMID:21818840 Ret Rat dabigatran multiple interactions EXP 6480464 Dabigatran inhibits the reaction [Rotenone results in decreased expression of RET protein] CTD PMID:28585189 Ret Rat DDD multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat DDE multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat DDT multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of RET mRNA CTD PMID:23914054 Ret Rat dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of RET mRNA CTD PMID:30359671 Ret Rat dexamethasone multiple interactions EXP 6480464 AGTR2 protein inhibits the reaction [Dexamethasone results in decreased expression of RET mRNA] and Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of RET mRNA] CTD PMID:30359671 Ret Rat diazinon affects expression EXP 6480464 Diazinon affects the expression of RET mRNA CTD PMID:22546817 Ret Rat dichromium trioxide multiple interactions ISO RET (Homo sapiens) 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of RET mRNA CTD PMID:12634122 Ret Rat diclofenac increases expression ISO Ret (Mus musculus) 6480464 Diclofenac results in increased expression of RET mRNA CTD PMID:26934552 Ret Rat dieldrin affects expression EXP 6480464 Dieldrin affects the expression of RET mRNA CTD PMID:22546817 Ret Rat dieldrin multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat diethylstilbestrol increases expression ISO RET (Homo sapiens) 6480464 Diethylstilbestrol results in increased expression of RET mRNA CTD PMID:26865669 Ret Rat dorsomorphin multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Ret Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of RET mRNA CTD PMID:29391264 Ret Rat endrin multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat Enterolactone multiple interactions ISO RET (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RET mRNA CTD PMID:19167446 Ret Rat entinostat increases expression ISO RET (Homo sapiens) 6480464 entinostat results in increased expression of RET mRNA CTD PMID:26272509 Ret Rat entinostat multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RET mRNA CTD PMID:27188386 Ret Rat estrone increases expression ISO RET (Homo sapiens) 6480464 Estrone results in increased expression of RET mRNA CTD PMID:26865669 Ret Rat ethanol affects expression ISO Ret (Mus musculus) 6480464 Ethanol affects the expression of RET mRNA CTD PMID:22198099 and PMID:30319688 Ret Rat ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of RET mRNA CTD PMID:29548890 and PMID:31039417 Ret Rat fonofos increases methylation ISO RET (Homo sapiens) 6480464 Fonofos results in increased methylation of RET promoter CTD PMID:22847954 Ret Rat fulvestrant decreases expression ISO RET (Homo sapiens) 6480464 fulvestrant results in decreased expression of RET mRNA CTD PMID:26865669 Ret Rat gamma-hexachlorocyclohexane multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat genistein increases expression EXP 6480464 Genistein results in increased expression of RET mRNA CTD PMID:12075121 Ret Rat genistein increases expression ISO RET (Homo sapiens) 6480464 Genistein results in increased expression of RET mRNA CTD PMID:26865669 Ret Rat glucose increases expression EXP 6480464 Glucose results in increased expression of RET mRNA CTD PMID:21818840 Ret Rat glyphosate increases expression ISO Ret (Mus musculus) 6480464 Glyphosate results in increased expression of RET mRNA CTD PMID:35897073 Ret Rat graphite affects expression EXP 6480464 Graphite affects the expression of RET mRNA CTD PMID:29933104 Ret Rat Indeno[1,2,3-cd]pyrene decreases expression ISO RET (Homo sapiens) 6480464 indeno(1 more ... CTD PMID:32251684 Ret Rat irbesartan increases expression ISO RET (Homo sapiens) 6480464 irbesartan results in increased expression of RET protein CTD PMID:16164579 Ret Rat ivermectin increases expression ISO RET (Homo sapiens) 6480464 Ivermectin results in increased expression of RET mRNA CTD PMID:33405908 Ret Rat ivermectin multiple interactions ISO RET (Homo sapiens) 6480464 ESR1 protein affects the reaction [Ivermectin results in increased expression of RET mRNA] CTD PMID:33405908 Ret Rat L-cysteine multiple interactions ISO RET (Homo sapiens) 6480464 Cysteine inhibits the reaction [[Arsenic co-treated with RET protein] results in increased secretion of MMP2 protein alternative form] CTD PMID:21195159 Ret Rat lead diacetate multiple interactions ISO RET (Homo sapiens) 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of RET mRNA CTD PMID:12634122 Ret Rat lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of RET mRNA CTD PMID:22641619 Ret Rat lipopolysaccharide multiple interactions ISO RET (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of RET mRNA CTD PMID:35811015 Ret Rat lithium atom multiple interactions EXP 6480464 [Lithium co-treated with Pilocarpine] results in increased expression of RET protein CTD PMID:12914250 Ret Rat lithium hydride multiple interactions EXP 6480464 [Lithium co-treated with Pilocarpine] results in increased expression of RET protein CTD PMID:12914250 Ret Rat manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of RET protein CTD PMID:17555550 Ret Rat Meclizine affects expression ISO RET (Homo sapiens) 6480464 Meclizine affects the expression of RET protein CTD PMID:12388792 Ret Rat medroxyprogesterone acetate multiple interactions ISO RET (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RET mRNA CTD PMID:20823114 Ret Rat megestrol affects expression ISO RET (Homo sapiens) 6480464 Megestrol affects the expression of RET protein CTD PMID:12388792 Ret Rat mercury dibromide decreases expression ISO RET (Homo sapiens) 6480464 mercuric bromide results in decreased expression of RET mRNA CTD PMID:26272509 Ret Rat mercury dibromide multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RET mRNA CTD PMID:27188386 Ret Rat mestranol increases expression ISO RET (Homo sapiens) 6480464 Mestranol results in increased expression of RET mRNA CTD PMID:26865669 Ret Rat methapyrilene increases methylation ISO RET (Homo sapiens) 6480464 Methapyrilene results in increased methylation of RET intron CTD PMID:30157460 Ret Rat Methazolamide affects expression ISO RET (Homo sapiens) 6480464 Methazolamide affects the expression of RET protein CTD PMID:12388792 Ret Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of RET mRNA and Methimazole results in increased expression of RET protein CTD PMID:22504374 Ret Rat methylmercury chloride decreases expression ISO RET (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of RET mRNA CTD PMID:28001369 Ret Rat methylphenidate decreases expression ISO Ret (Mus musculus) 6480464 Methylphenidate results in decreased expression of RET mRNA CTD PMID:22470460 Ret Rat mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of RET mRNA] CTD PMID:30359671 Ret Rat N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide affects expression ISO RET (Homo sapiens) 6480464 Methazolamide affects the expression of RET protein CTD PMID:12388792 Ret Rat N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of RET mRNA CTD PMID:16026605 Ret Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RET mRNA CTD PMID:20360939 Ret Rat nickel atom decreases expression ISO RET (Homo sapiens) 6480464 Nickel results in decreased expression of RET mRNA CTD PMID:24768652 and PMID:25583101 Ret Rat nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of RET mRNA CTD PMID:22546817 Ret Rat Nor-9-carboxy-delta9-THC multiple interactions ISO RET (Homo sapiens) 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of RET gene CTD PMID:30521419 Ret Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of RET mRNA CTD PMID:25729387 Ret Rat oxidopamine decreases response to substance ISO Ret (Mus musculus) 6480464 RET protein mutant form results in decreased susceptibility to Oxidopamine CTD PMID:19767128 Ret Rat p-chloromercuribenzoic acid decreases expression ISO RET (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of RET mRNA CTD PMID:26272509 Ret Rat p-chloromercuribenzoic acid multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RET mRNA CTD PMID:27188386 Ret Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of RET mRNA CTD PMID:30723492 Ret Rat parathion increases methylation ISO RET (Homo sapiens) 6480464 Parathion results in increased methylation of RET promoter CTD PMID:22847954 Ret Rat PCB138 multiple interactions ISO Ret (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 Ret Rat pentanal increases expression ISO RET (Homo sapiens) 6480464 pentanal results in increased expression of RET mRNA CTD PMID:26079696 Ret Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RET mRNA CTD PMID:35163327 Ret Rat phenethyl caffeate multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RET mRNA CTD PMID:20360939 Ret Rat phenylmercury acetate decreases expression ISO RET (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of RET mRNA CTD PMID:26272509 Ret Rat phenylmercury acetate multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RET mRNA CTD PMID:27188386 Ret Rat picene decreases expression ISO RET (Homo sapiens) 6480464 picene results in decreased expression of RET mRNA CTD PMID:32251684 Ret Rat pinostrobin increases expression ISO RET (Homo sapiens) 6480464 pinostrobin results in increased expression of RET mRNA CTD PMID:37777166 Ret Rat ponatinib decreases activity ISO RET (Homo sapiens) 6480464 ponatinib analog results in decreased activity of RET protein more ... CTD PMID:19878872 and PMID:21561767 Ret Rat propanal increases expression ISO RET (Homo sapiens) 6480464 propionaldehyde results in increased expression of RET mRNA CTD PMID:26079696 Ret Rat Ptaquiloside decreases expression ISO Ret (Mus musculus) 6480464 ptaquiloside results in decreased expression of RET mRNA CTD PMID:23274088 Ret Rat raloxifene multiple interactions ISO RET (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RET mRNA and [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA CTD PMID:19059307 Ret Rat raloxifene decreases expression ISO RET (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased expression of RET mRNA CTD PMID:26865669 Ret Rat resveratrol multiple interactions ISO RET (Homo sapiens) 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of RET mRNA and [Plant Extracts co-treated with Resveratrol] results in decreased expression of RET mRNA CTD PMID:19167446 and PMID:23557933 Ret Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of RET mRNA and Rotenone results in decreased expression of RET protein CTD PMID:17555550 more ... Ret Rat rotenone multiple interactions EXP 6480464 Dabigatran inhibits the reaction [Rotenone results in decreased expression of RET protein] CTD PMID:28585189 Ret Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RET (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of RET mRNA CTD PMID:35811015 Ret Rat SB 431542 multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Ret Rat simvastatin multiple interactions ISO RET (Homo sapiens) 6480464 [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 Ret Rat sodium arsenite multiple interactions ISO RET (Homo sapiens) 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of RET mRNA CTD PMID:12634122 Ret Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of RET mRNA CTD PMID:35314868 Ret Rat sodium arsenite increases expression ISO RET (Homo sapiens) 6480464 sodium arsenite results in increased expression of RET mRNA CTD PMID:38568856 Ret Rat sodium arsenite affects methylation ISO RET (Homo sapiens) 6480464 sodium arsenite affects the methylation of RET gene CTD PMID:28589171 Ret Rat Soman increases expression EXP 6480464 Soman results in increased expression of RET mRNA CTD PMID:19281266 Ret Rat sorafenib decreases activity ISO RET (Homo sapiens) 6480464 Sorafenib results in decreased activity of RET protein and Sorafenib results in decreased activity of RET protein mutant form CTD PMID:17664273 Ret Rat sorafenib increases degradation ISO RET (Homo sapiens) 6480464 sorafenib results in increased degradation of RET protein CTD PMID:17664273 Ret Rat staurosporine decreases expression EXP 6480464 Staurosporine results in decreased expression of RET protein CTD PMID:17555550 Ret Rat sulindac affects expression ISO RET (Homo sapiens) 6480464 Sulindac affects the expression of RET protein CTD PMID:12388792 Ret Rat tamoxifen multiple interactions ISO RET (Homo sapiens) 6480464 [Tamoxifen co-treated with ESR1 protein] results in increased expression of RET mRNA more ... CTD PMID:19059307 and PMID:24758408 Ret Rat tebuconazole decreases expression ISO RET (Homo sapiens) 6480464 tebuconazole results in decreased expression of RET mRNA CTD PMID:30458266 Ret Rat terbufos increases methylation ISO RET (Homo sapiens) 6480464 terbufos results in increased methylation of RET promoter CTD PMID:22847954 Ret Rat tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of RET mRNA CTD PMID:12734012 Ret Rat thapsigargin decreases expression ISO RET (Homo sapiens) 6480464 Thapsigargin results in decreased expression of RET mRNA CTD PMID:22378314 Ret Rat titanium dioxide decreases expression ISO Ret (Mus musculus) 6480464 titanium dioxide results in decreased expression of RET mRNA CTD PMID:29264374 Ret Rat titanium dioxide decreases methylation ISO Ret (Mus musculus) 6480464 titanium dioxide results in decreased methylation of RET gene CTD PMID:35295148 Ret Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of RET mRNA CTD PMID:25729387 Ret Rat trichostatin A increases expression ISO RET (Homo sapiens) 6480464 trichostatin A results in increased expression of RET mRNA CTD PMID:24935251 Ret Rat triclosan decreases expression ISO RET (Homo sapiens) 6480464 Triclosan results in decreased expression of RET mRNA CTD PMID:30510588 Ret Rat triptonide increases expression ISO Ret (Mus musculus) 6480464 triptonide results in increased expression of RET mRNA CTD PMID:33045310 Ret Rat tunicamycin decreases expression ISO RET (Homo sapiens) 6480464 Tunicamycin results in decreased expression of RET mRNA CTD PMID:22378314 Ret Rat valproic acid increases methylation ISO RET (Homo sapiens) 6480464 Valproic Acid results in increased methylation of RET gene CTD PMID:29154799 Ret Rat valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of RET mRNA CTD PMID:33150595 Ret Rat valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of RET promoter CTD PMID:33150595 Ret Rat valproic acid multiple interactions EXP 6480464 [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RET protein and [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter] CTD PMID:32526256 Ret Rat valproic acid multiple interactions ISO RET (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RET mRNA CTD PMID:27188386 Ret Rat valproic acid increases expression ISO RET (Homo sapiens) 6480464 Valproic Acid results in increased expression of RET mRNA CTD PMID:23179753 more ... Ret Rat valproic acid affects expression ISO RET (Homo sapiens) 6480464 Valproic Acid affects the expression of RET mRNA CTD PMID:25979313 Ret Rat valproic acid affects expression ISO Ret (Mus musculus) 6480464 Valproic Acid affects the expression of RET mRNA CTD PMID:17963808 Ret Rat vandetanib decreases phosphorylation ISO RET (Homo sapiens) 6480464 vandetanib results in decreased phosphorylation of RET protein CTD PMID:17431108 Ret Rat verapamil affects expression ISO RET (Homo sapiens) 6480464 Verapamil affects the expression of RET protein CTD PMID:12388792 Ret Rat vorinostat decreases expression ISO RET (Homo sapiens) 6480464 vorinostat results in decreased expression of RET mRNA CTD PMID:27188386
Imported Annotations - KEGG (archival)
(+)-pilocarpine (EXP) (-)-anisomycin (EXP) 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO) 17alpha-ethynylestradiol (EXP) 17beta-estradiol (ISO) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,2',5,5'-tetrachlorobiphenyl (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 5-azacytidine (ISO) 6-propyl-2-thiouracil (EXP) afimoxifene (ISO) aflatoxin B1 (ISO) aldehydo-D-glucose (EXP) aldrin (ISO) all-trans-retinoic acid (EXP,ISO) all-trans-retinol (EXP) alpha-Zearalanol (EXP) amitrole (EXP) ammonium chloride (EXP) arsane (ISO) arsenic atom (ISO) atrazine (EXP) benzo[a]pyrene (EXP,ISO) benzo[e]pyrene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO) bucladesine (ISO) butanal (ISO) cadmium dichloride (ISO) calcitriol (ISO) camptothecin (EXP) chlordecone (ISO) chlorpyrifos (ISO) cisplatin (EXP) clomiphene (ISO) copper(II) sulfate (ISO) coumestrol (ISO) Cuprizon (EXP) cycloheximide (EXP) D-glucose (EXP) dabigatran (EXP) DDD (ISO) DDE (ISO) DDT (ISO) decabromodiphenyl ether (EXP) dexamethasone (EXP) diazinon (EXP) dichromium trioxide (ISO) diclofenac (ISO) dieldrin (EXP,ISO) diethylstilbestrol (ISO) dorsomorphin (ISO) endosulfan (EXP) endrin (ISO) Enterolactone (ISO) entinostat (ISO) estrone (ISO) ethanol (EXP,ISO) fonofos (ISO) fulvestrant (ISO) gamma-hexachlorocyclohexane (ISO) genistein (EXP,ISO) glucose (EXP) glyphosate (ISO) graphite (EXP) Indeno[1,2,3-cd]pyrene (ISO) irbesartan (ISO) ivermectin (ISO) L-cysteine (ISO) lead diacetate (EXP,ISO) lipopolysaccharide (ISO) lithium atom (EXP) lithium hydride (EXP) manganese(II) chloride (EXP) Meclizine (ISO) medroxyprogesterone acetate (ISO) megestrol (ISO) mercury dibromide (ISO) mestranol (ISO) methapyrilene (ISO) Methazolamide (ISO) methimazole (EXP) methylmercury chloride (ISO) methylphenidate (ISO) mifepristone (EXP) N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide (ISO) N-methyl-4-phenylpyridinium (EXP) N-nitrosodiethylamine (EXP) nickel atom (ISO) nickel dichloride (EXP) Nor-9-carboxy-delta9-THC (ISO) oxaliplatin (EXP) oxidopamine (ISO) p-chloromercuribenzoic acid (ISO) paracetamol (EXP) parathion (ISO) PCB138 (ISO) pentanal (ISO) perfluorooctanoic acid (EXP) phenethyl caffeate (EXP) phenylmercury acetate (ISO) picene (ISO) pinostrobin (ISO) ponatinib (ISO) propanal (ISO) Ptaquiloside (ISO) raloxifene (ISO) resveratrol (ISO) rotenone (EXP) S-(1,2-dichlorovinyl)-L-cysteine (ISO) SB 431542 (ISO) simvastatin (ISO) sodium arsenite (EXP,ISO) Soman (EXP) sorafenib (ISO) staurosporine (EXP) sulindac (ISO) tamoxifen (ISO) tebuconazole (ISO) terbufos (ISO) tetrachloromethane (EXP) thapsigargin (ISO) titanium dioxide (ISO) topotecan (EXP) trichostatin A (ISO) triclosan (ISO) triptonide (ISO) tunicamycin (ISO) valproic acid (EXP,ISO) vandetanib (ISO) verapamil (ISO) vorinostat (ISO)
1.
Up-regulation of GDNFR-alpha and c-ret mRNA in facial motor neurons following facial nerve injury in the rat.
Burazin TC and Gundlach AL, Brain Res Mol Brain Res. 1998 Apr;55(2):331-6.
2.
Genetic mapping of the RET protooncogene on rat chromosome 4.
Canzian F, etal., Mamm Genome 1995 Jun;6(6):433-5.
3.
Time-course of GDNF and its receptor expression after brain injury in the rat.
Cheng Q, etal., Neurosci Lett. 2008 Jul 4;439(1):24-9. Epub 2008 May 1.
4.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
6.
The Shp-1 and Shp-2, tyrosine phosphatases, are recruited on cell membrane in two distinct molecular complexes including Ret oncogenes.
Incoronato M, etal., Cell Signal. 2004 Jul;16(7):847-56.
7.
Expression of glial cell line-derived neurotrophic factor family members and their receptors in pancreatic cancers.
Ito Y, etal., Surgery. 2005 Oct;138(4):788-94.
8.
Hirschsprung disease is linked to defects in neural crest stem cell function.
Iwashita T, etal., Science 2003 Aug 15;301(5635):972-6.
9.
Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth.
Jiao L, etal., Cell Res. 2011 Feb;21(2):327-37. doi: 10.1038/cr.2010.139. Epub 2010 Sep 28.
10.
Induction of glial cell line-derived neurotrophic factor receptor proteins in cerebral cortex and striatum after permanent middle cerebral artery occlusion in rats.
Kitagawa H, etal., Brain Res. 1999 Jul 10;834(1-2):190-5.
11.
Regulation of GDNF and its receptor components GFR-alpha1, -alpha2 and Ret during development and in the mature retino-collicular pathway.
Kretz A, etal., Brain Res. 2006 May 23;1090(1):1-14. Epub 2006 May 2.
12.
Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease.
Marco S, etal., J Neurobiol. 2002 Sep 15;52(4):343-51.
13.
cDNA sequence and genomic structure of the rat RET proto-oncogene.
Matera I, etal., DNA Seq 2000;11(5):405-17.
14.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
15.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
16.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
17.
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.
Pierchala BA, etal., J Neurosci. 2006 Mar 8;26(10):2777-87.
18.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
19.
Adrenergic differentiation and Ret expression in rat pheochromocytomas.
Powers JF, etal., Endocr Pathol. 2008 Spring;19(1):9-16.
20.
Up-regulation of ret by reserpine in the adult rat adrenal medulla.
Powers JF, etal., Neuroscience. 2005;132(3):605-12.
21.
GOA pipeline
RGD automated data pipeline
22.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
24.
Comprehensive gene review and curation
RGD comprehensive gene curation
25.
The long and short isoforms of Ret function as independent signaling complexes.
Tsui-Pierchala BA, etal., J Biol Chem 2002 Sep 13;277(37):34618-25. Epub 2002 Jun 28.
26.
Discordant expression of c-Ret and glial cell line-derived neurotrophic factor receptor alpha-1 mRNAs in response to motor nerve injury in neonate rats.
Tsujino H, etal., Brain Res Mol Brain Res. 1999 Jul 5;70(2):298-303.
27.
RET variants and haplotype analysis in a cohort of Czech patients with Hirschsprung disease.
Vaclavikova E, etal., PLoS One. 2014 Jun 4;9(6):e98957. doi: 10.1371/journal.pone.0098957. eCollection 2014.
28.
Upregulation of glial cell line-derived neurotrophic factor and artemin mRNA in the auditory nerve of deafened rats.
Wissel K, etal., Neuroreport. 2006 Jun 26;17(9):875-8.
29.
The relationship between overexpression of glial cell-derived neurotrophic factor and its RET receptor with progression and prognosis of human pancreatic cancer.
Zeng Q, etal., J Int Med Res. 2008 Jul-Aug;36(4):656-64.
30.
A common RET variant is associated with reduced newborn kidney size and function.
Zhang Z, etal., J Am Soc Nephrol. 2008 Oct;19(10):2027-34. doi: 10.1681/ASN.2007101098.
31.
Diagnosis and surgical treatment of multiple endocrine neoplasia.
Zhou GW, etal., Chin Med J (Engl). 2009 Jul 5;122(13):1495-500.
Ret (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 4 152,998,344 - 153,040,556 (-) NCBI GRCr8 mRatBN7.2 4 151,325,969 - 151,368,176 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 4 151,326,431 - 151,368,176 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 4 157,589,266 - 157,631,480 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 4 153,373,235 - 153,415,450 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 4 151,996,254 - 152,038,470 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 4 150,202,170 - 150,249,196 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 4 150,202,058 - 150,244,372 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 4 216,130,142 - 216,177,139 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 4 154,448,179 - 154,491,103 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 4 154,693,019 - 154,735,944 (-) NCBI Celera 4 140,198,457 - 140,240,663 (-) NCBI Celera Cytogenetic Map 4 q42 NCBI
RET (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 10 43,077,069 - 43,130,351 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 10 43,077,064 - 43,130,351 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 10 43,572,517 - 43,625,799 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 10 42,892,523 - 42,945,805 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 10 42,892,532 - 42,944,955 NCBI Celera 10 39,575,663 - 39,628,954 (+) NCBI Celera Cytogenetic Map 10 q11.21 NCBI HuRef 10 40,098,756 - 40,151,896 (+) NCBI HuRef CHM1_1 10 43,611,715 - 43,665,000 (+) NCBI CHM1_1 T2T-CHM13v2.0 10 43,954,542 - 44,007,848 (+) NCBI T2T-CHM13v2.0
Ret (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 6 118,128,709 - 118,174,705 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 6 118,128,706 - 118,174,679 (-) Ensembl GRCm39 Ensembl GRCm38 6 118,151,748 - 118,197,744 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 6 118,151,745 - 118,197,718 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 6 118,101,766 - 118,147,762 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 6 118,119,472 - 118,162,752 (-) NCBI MGSCv36 mm8 Celera 6 119,974,414 - 120,020,450 (-) NCBI Celera Cytogenetic Map 6 F1 NCBI cM Map 6 55.86 NCBI
Ret (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955546 1,221,995 - 1,253,946 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955546 1,221,995 - 1,252,147 (+) NCBI ChiLan1.0 ChiLan1.0
RET (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 8 55,790,324 - 55,866,889 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 10 55,795,492 - 55,848,773 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 10 40,050,396 - 40,103,629 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 10 43,256,437 - 43,286,340 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 10 43,249,468 - 43,284,331 (+) Ensembl panpan1.1 panPan2
RET (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 28 3,946,132 - 3,995,505 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 28 3,947,232 - 3,994,210 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 28 4,180,472 - 4,211,554 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 28 4,124,929 - 4,176,146 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 28 4,126,037 - 4,174,867 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 28 3,922,935 - 3,954,018 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 28 3,965,997 - 3,997,076 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 28 4,100,288 - 4,131,400 (-) NCBI UU_Cfam_GSD_1.0
Ret (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024407213 83,803,446 - 83,856,824 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936617 2,927,155 - 2,980,602 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936617 2,927,185 - 2,980,594 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
RET (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 14 61,305,841 - 61,361,412 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 14 61,305,818 - 61,361,416 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 14 66,136,477 - 66,192,220 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
RET (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 9 38,746,088 - 38,798,773 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 9 38,769,170 - 38,796,712 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666056 47,691,006 - 47,743,756 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Ret (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 445 Count of miRNA genes: 245 Interacting mature miRNAs: 296 Transcripts: ENSRNOT00000047685 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
6478754 Anxrr43 Anxiety related response QTL 43 0.14035 locomotor behavior trait (VT:0001392) distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493) 4 144639524 182687754 Rat 724558 Plsm2 Polydactyly-luxate syndrome (PLS) morphotypes QTL 2 0.0003 hindlimb integrity trait (VT:0010563) hind foot phalanges count (CMO:0001949) 4 132422778 177422778 Rat 1582237 Kidm34 Kidney mass QTL 34 4 0.0001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 4 148090542 168069246 Rat 61446 Coreg2 Compensatory renal growth QTL 2 3.5 kidney mass (VT:0002707) compensatory renal growth score (CMO:0001894) 4 148423102 157580971 Rat 6478693 Anxrr32 Anxiety related response QTL 32 0.00092 locomotor behavior trait (VT:0001392) measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957) 4 144639524 182687754 Rat 10755501 Bp390 Blood pressure QTL 390 2.5 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 4 26775591 168368347 Rat 6478763 Anxrr46 Anxiety related response QTL 46 0.07428 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 4 110870972 155870972 Rat 6478760 Anxrr45 Anxiety related response QTL 45 0.06717 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 4 110870972 155870972 Rat 631683 Bp116 Blood pressure QTL 116 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 4 124303370 169303370 Rat 61451 Ciaa4 CIA Autoantibody QTL 4 3.1 blood autoantibody amount (VT:0003725) calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281) 4 126395976 167139601 Rat 1331802 Srn5 Serum renin concentration QTL 5 3.045 renin activity (VT:0005581) plasma renin activity level (CMO:0000116) 4 119428175 157578333 Rat 1331738 Bp209 Blood pressure QTL 209 2.979 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 4 138503169 179293946 Rat 6478700 Anxrr33 Anxiety related response QTL 33 0.00896 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 4 144639524 182687754 Rat 1298524 Oia8 Oil induced arthritis QTL 8 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 4 138503169 173369699 Rat 738009 Sach4 Saccharine consumption QTL 4 4.9 0.000016 consumption behavior trait (VT:0002069) saccharin intake volume to total fluid intake volume ratio (CMO:0001601) 4 59948935 154902892 Rat 1549827 Scl46 Serum cholesterol level QTL 46 3.5 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 4 132396220 177396220 Rat 7207480 Bss105 Bone structure and strength QTL 105 8.1 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 4 109827074 154827074 Rat 634335 Anxrr16 Anxiety related response QTL 16 7.22 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 4 93308457 167139447 Rat 731165 Uae21 Urinary albumin excretion QTL 21 2.4 0.0001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 4 106649412 151649412 Rat 737821 Hcar9 Hepatocarcinoma resistance QTL 9 3.7 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 4 109866907 167139601 Rat 7411558 Bw133 Body weight QTL 133 13.84 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 4 125590636 170590636 Rat 6478778 Anxrr51 Anxiety related response QTL 51 0.25384 locomotor behavior trait (VT:0001392) measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957) 4 124778595 169778595 Rat 10401796 Kidm48 Kidney mass QTL 48 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 4 145568712 182687754 Rat 6478718 Anxrr34 Anxiety related response QTL 34 0.00896 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 4 144639524 182687754 Rat 61406 Scwia1 Streptococcal cell wall induced arthritis QTL 1 2.3 joint integrity trait (VT:0010548) experimental arthritis severity measurement (CMO:0001459) 4 106805662 151805662 Rat 631511 Pia7 Pristane induced arthritis QTL 7 4.3 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 4 131730738 167139601 Rat 1549832 Bss3 Bone structure and strength QTL 3 11 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 4 109827074 154827074 Rat 70177 Xhs1 X-ray hypersensitivity QTL 1 25.1 intestine integrity trait (VT:0010554) post-insult time to onset of moribundity (CMO:0001896) 4 82798864 152731274 Rat 634347 Hcar8 Hepatocarcinoma resistance QTL 8 5.8 liver integrity trait (VT:0010547) liver tumorous lesion area to total liver area ratio (CMO:0001075) 4 123143783 168143783 Rat 738031 Alc14 Alcohol consumption QTL 14 7.6 0.00003 consumption behavior trait (VT:0002069) ethanol drink intake rate to body weight ratio (CMO:0001616) 4 59948935 154902892 Rat 1576316 Ept5 Estrogen-induced pituitary tumorigenesis QTL 5 3.8 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 4 83428419 177635233 Rat 2303623 Vencon2 Ventilatory control QTL 2 3.8 respiration trait (VT:0001943) minute ventilation (CMO:0000132) 4 135204660 180204660 Rat 1576305 Emca6 Estrogen-induced mammary cancer QTL 6 5.8 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 4 44463720 155883716 Rat 1578674 Bmd12 Bone mineral density QTL 12 3.8 femur mineral mass (VT:0010011) compact volumetric bone mineral density (CMO:0001730) 4 135699135 180699135 Rat 738016 Alc16 Alcohol consumption QTL 16 3.6 0.00015 consumption behavior trait (VT:0002069) ethanol drink intake rate to body weight ratio (CMO:0001616) 4 59948935 154902892 Rat 1358202 Gluco11 Glucose level QTL 11 2.4 0.02 adipocyte glucose uptake trait (VT:0004185) absolute change in adipocyte glucose uptake (CMO:0000873) 4 85379421 167139601 Rat 61422 Cia13 Collagen induced arthritis QTL 13 4.5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 4 132642577 167139601 Rat 634342 Cia24 Collagen induced arthritis QTL 24 4.5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 4 146565735 175236377 Rat 737978 Pia23 Pristane induced arthritis QTL 23 5.3 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 4 131730738 167139601 Rat 61362 Oia2 Oil induced arthritis QTL 2 0.001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 4 138503169 173369699 Rat 631674 Iddm14 Insulin dependent diabetes mellitus QTL 14 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 4 64528739 157573521 Rat 12798519 Anxrr54 Anxiety related response QTL 54 2.54 0.05 locomotor behavior trait (VT:0001392) distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493) 4 114627026 159627026 Rat 2293659 Bmd35 Bone mineral density QTL 35 4.5 0.0001 femur strength trait (VT:0010010) femoral neck ultimate force (CMO:0001703) 4 137755016 181392681 Rat 1331759 Hrtrt13 Heart rate QTL 13 3.54628 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 4 110275411 168266883 Rat 724535 Cm18 Cardiac mass QTL 18 2.6 heart mass (VT:0007028) calculated heart weight (CMO:0000073) 4 118856416 163856416 Rat 2316958 Gluco58 Glucose level QTL 58 10 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 4 11320076 180699135 Rat 6478748 Anxrr42 Anxiety related response QTL 42 0.28008 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 4 144639524 182687754 Rat 12798525 Anxrr57 Anxiety related response QTL 57 3.21 0.05 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 4 147278504 167139601 Rat
AA859878
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 4 151,328,880 - 151,329,062 (+) MAPPER mRatBN7.2 Rnor_6.0 4 150,205,086 - 150,205,267 NCBI Rnor6.0 Rnor_5.0 4 216,133,054 - 216,133,235 UniSTS Rnor5.0 RGSC_v3.4 4 154,451,091 - 154,451,272 UniSTS RGSC3.4 Celera 4 140,201,369 - 140,201,550 UniSTS RH 3.4 Map 4 969.31 UniSTS Cytogenetic Map 4 q42 UniSTS
Ret
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 4 151,329,531 - 151,329,638 (+) MAPPER mRatBN7.2 Rnor_6.0 4 150,205,737 - 150,205,843 NCBI Rnor6.0 Rnor_5.0 4 216,133,705 - 216,133,811 UniSTS Rnor5.0 RGSC_v3.4 4 154,451,742 - 154,451,848 UniSTS RGSC3.4 Celera 4 140,202,020 - 140,202,126 UniSTS Cytogenetic Map 4 q42 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
85
84
53
25
53
6
210
97
93
43
60
31
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Ensembl Acc Id:
ENSRNOT00000047685 ⟹ ENSRNOP00000047793
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 4 151,326,431 - 151,368,176 (-) Ensembl Rnor_6.0 Ensembl 4 150,202,058 - 150,244,372 (-) Ensembl
RefSeq Acc Id:
NM_001110099 ⟹ NP_001103569
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 4 153,001,167 - 153,040,556 (-) NCBI mRatBN7.2 4 151,328,786 - 151,368,176 (-) NCBI Rnor_6.0 4 150,204,991 - 150,244,380 (-) NCBI Rnor_5.0 4 216,130,142 - 216,177,139 (-) NCBI RGSC_v3.4 4 154,448,179 - 154,491,103 (-) RGD Celera 4 140,201,274 - 140,240,663 (-) NCBI
Sequence:
GCGCGCACGGGCGATGGCGAAAGCGAGGTCCGGCGCCGCAGGGCTGGGGCTGAAGCTGTTTTTGCTGCTGCCGCTACTGGGAGAAGCCCCGCTGGGTCTCTACTTCTCAAGGGATGCTTACTGGGAGA GGCTGTATGTGGACCAGCCAGCTGGCACACCTCTGCTCTATGTCCATGCCCTACGGGATGCCCCTGGAGAAGTGCCCAGCTTCCGCCTGGGCCAGTATCTCTATGGCGTCTACCGCACGCGTCTGCAT GAGAATGACTGGATCCACATCGATTCGGGCACTGGCCTCCTCTACCTCAATCAGAGCCTGGACCATAGTTCCTGGGAGCAGCTCAGCATCCGCAATGGCGGCTTCCCCTTGCTCACCGTCTTCCTCCA GGTCTTCCTGGGGTCCACAGCCCAGAGAGAGGGAGAGTGTCATTGGCCAGGCTGTGCCCGTGTGTACTTCTCCTTCATCAACGACACCTTCCCAAATTGTAGCTCCTTCAAAGCCCGGGATCTCTGCA CCCCGGAGACGGGTGTGTCCTTCCGCATCAGGGAGAACAGGCCCCCTGGCACCTTCTACCAGTTCCGCATGCTACCTGTGCAGTTCCTTTGTCCTAACATCAGTGTGAAGTACAAACTCTTAGAAGGG GACGGTCTGCCCTTCCGTTGTGACCCCGACTGTCTGGAGGTGAGCACGCGGTGGGCGCTGGATCGGGAGCTTCAGGAGAAGTATGTGCTGGAGGCTGAGTGCGCAGTGGCAGGCCCTGGAGCCAACAA GGAGAAGGTGGCCGTGTCCTTCCCGGTGACGGTGTATGATGAAGACGACTCCCCGCCCACCTTCTCCGGAGGTGTGGGCACCGCCAGTGCTGTGGTGGAGTTTAAGCGGAAGGAGGGCACTGTGGTAG CCACTCTGCAGGTGTTTGATGCAGATGTGGTGCCAGCATCTGGGGAGCTGGTGAGGCGGTACACAAGCACACTACTCTCAGGGGATTCCTGGGCCCAGCAGACCTTCCGGGTGGAGCACACACCCAAC GAGACCTTGGTCCAGTCCAACAACAACTCCGTGCGGGCAACCATGCACAATTACAAGCTGGTTCTCAACAGGAGCCTGTCCATCTCAGAGAGCCGAGTCCTGCAGCTAGTAGTCCTGGTCAATGACTC AGACTTCCAGGGGCCTGGGTCAGGTGTTCTCTTCCTCCATTTCAACGTGTCTGTGCTGCCTGTCACCCTGAACCTACCCATGGCCTACTCCTTCCCAGTGAATAGGAGAGCCCGCCGTTATGCCCAGA TTGGGAAAGTTTGCGTGGAGAACTGCCAGGAGTTCAGCGGTGTCTCCATCCAGTACAAGCTGCAGCCCTCCAGCACCAACTGCAGTGCCCTAGGTGTGGTCACCTCAACAGAAGACACCTCAGGGACC CTATATGTAAATGACACGGAGGCCCTGCGGCGACCTGAGTGTACCGAGCTTCAGTACACAGTGGTAGCCACTGACCGGCAGACCCGCAGGCAGACCCAGGCTTCGTTAGTCGTCACAGTGGAGGGGAC ATACATTGCAGAAGAAGTGGGCTGCCCCAAGTCCTGTGCAGTAAACAAGAGGCGACCTGAGTGTGAGGAGTGTGGTGGCCTGGGTTCTCCAACTGGCAGATGTGAGTGGCGTCAGGGAGATGGTAAAG GGATCACCAGGAACTTCTCCACCTGTTCTCCTAGCACCAGGACCTGTCCTGATGGCCACTGTGATGCTCTGGAGAGCCGGGATATCAACATTTGCCCCCAGGACTGTCTCCGTGGCCCCATTGTTGGC GGGCATGAGCGAGGGGAGCGCCAGGGGATTAAAGCCGGCTATGGCATCTGCAACTGTTTCCCTGATGAGAAGAAGTGCTTCTGCGAGCCAGAGGACAGCCAGGGCCCATTGTGCGATGAGCTGTGCCG TACGGTCATCACAGCCGCTGTCCTCTTCTCCTTCATAATCTCTGTCCTGCTGTCCACCTTCTGCATCCACCGCTACCACAAGCATGCGCACAAGCCACCCATCGCGTCAGCCGAAATGACCTTCTGCC GGCCGGCCCAGGGCTTCCCAATCAGCTATTCTTCCTCGGGCACCCGCCGGCCCTCACTGGACTCCATGGAGAACCAGGTCTCTGTGGACTCTTTCAAGATCCCGGAGGATCCGAAGTGGGAATTTCCT CGGAAGAACTTAGTTCTTGGGAAAACCCTGGGAGAAGGCGAGTTTGGAAAAGTAGTCAAGGCCACAGCCTTCCGTCTGAAAGGCCGGGCAGGATACACCACAGTGGCTGTGAAAATGCTGAAAGAAAA CGCCTCCCAGAGTGAACTACGAGACCTGCTCTCTGAGTTCAACCTTCTGAAACAAGTCAACCATCCACATGTCATCAAGTTGTACGGGGCTTGCAGCCAGGATGGGCCACTTCTTCTCATTGTGGAGT ATGCAAAGTATGGATCCCTGCGGGGGTTCCTGCGGGACAGCCGCAAGATCGGGCCTGCCTATGTGAGCAGTGGAGGCAGCCGCAATTCCAGCTCCCTGGACCACCCAGACGAAAGGGTGCTGACCATG GGCGACCTCATCTCCTTCGCCTGGCAGATCTCGAGGGGTATGCAGTACTTGGCTGAAATGAAGCTCGTACATCGAGACTTAGCTGCCAGAAACATCTTGGTGGCAGAGGGACGGAAGATGAAGATCTC TGACTTTGGGCTGTCCCGAGATGTTTATGAAGAAGATTCCTATGTGAAGAAAAGCAAGGGCCGGATTCCCGTCAAATGGATGGCAATCGAGTCTCTCTTCGATCACATCTATACCACTCAAAGTGATG TGTGGTCCTTTGGAGTGCTGCTATGGGAGATTGTGACCCTGGGAGGCAACCCCTACCCTGGAATTCCTCCTGAACGACTCTTCAACCTTCTGAAGACAGGCCACAGGATGGAGAGGCCAGACAACTGC AGCGAGGAAATGTACCGCCTGATGCTGCAGTGCTGGAAGCAGGAGCCGGACAAGAGGCCAGTATTTGCTGACATCAGCAAGGATCTGGAGAAGATGATGGTCAAAAGCAGAGACTACTTGGACCTGGC TGCATCCACCCCTTCGGACTCACTGCTCTATGACGATGGGCTCTCGGAAGAGGAGACGCCCCTGGTGGACTGTAACAGTGCTCCCCTCCCGCGCTCCCTCCCTTCCACATGGATTGAAAACAAACTCT ATGGTAGAATTTCACATGCATTTACTAGATTCTAGCAACGCAGTCCCCTCTGCACCATCCCAACTGTCTGTAACGCTTTTTAAGAGTGTTTCCGATCCCACCGAAACCAAAGCCTCCTCTGAACCCTT TTCTTTGTAAATATCCGACTTTGCACCTAGTTTACACACATTCAGGCATTTTGCAGCTATGTCTTTCTAAAAGGATGTGAAAATAAAGTGTCACTACCACACAGCCCGGCAACTTAAGATGACACTGG AGAAGCAGATTAGAGCAGAATTCTCAGGGGCTGTTGGGAAGCAAATCATAGTACTTCTGACTTCGTTACTTAAATTTACCTGATCTGGGGAGGGAGGGAATTTTGCCAGGGAATGCTGGCACCCCCAA CTTGTAGTGACAGCATAGCTAGGGTATCCCCAGGCTGCTCCTAGGCTGGTGTGTGCCTCGTGGAAGCCGTCCATATTCACACTTCCAGCTCTGTGTCCACCGTCATGCAGTGTGGGGCAGCGGGGAAA CCACGTGGGCCCTGGGCAGACACCAAACTGCTGCTTTCACATCCTTTGCACCCTACCCCCCACATCATGATGATGTCACTCACGAAGCCAGTGCTAAATACTGAGCCAATGCTTTCTGAAAGAACATA GTCTGTGGTGCTGTGGCCTTGCAATGGACAGTAAACACGGTTCTTGCCAAAACTCCTCCTTTGTCTTGGATTAAATACTTGACATTTT
hide sequence
RefSeq Acc Id:
NM_012643 ⟹ NP_036775
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 4 152,998,350 - 153,040,556 (-) NCBI mRatBN7.2 4 151,325,969 - 151,368,176 (-) NCBI Rnor_6.0 4 150,202,174 - 150,244,380 (-) NCBI Rnor_5.0 4 216,130,142 - 216,177,139 (-) NCBI RGSC_v3.4 4 154,448,179 - 154,491,103 (-) RGD Celera 4 140,198,457 - 140,240,663 (-) RGD
Sequence:
GCGCGCACGGGCGATGGCGAAAGCGAGGTCCGGCGCCGCAGGGCTGGGGCTGAAGCTGTTTTTGCTGCTGCCGCTACTGGGAGAAGCCCCGCTGGGTCTCTACTTCTCAAGGGATGCTTACTGGGAGA GGCTGTATGTGGACCAGCCAGCTGGCACACCTCTGCTCTATGTCCATGCCCTACGGGATGCCCCTGGAGAAGTGCCCAGCTTCCGCCTGGGCCAGTATCTCTATGGCGTCTACCGCACGCGTCTGCAT GAGAATGACTGGATCCACATCGATTCGGGCACTGGCCTCCTCTACCTCAATCAGAGCCTGGACCATAGTTCCTGGGAGCAGCTCAGCATCCGCAATGGCGGCTTCCCCTTGCTCACCGTCTTCCTCCA GGTCTTCCTGGGGTCCACAGCCCAGAGAGAGGGAGAGTGTCATTGGCCAGGCTGTGCCCGTGTGTACTTCTCCTTCATCAACGACACCTTCCCAAATTGTAGCTCCTTCAAAGCCCGGGATCTCTGCA CCCCGGAGACGGGTGTGTCCTTCCGCATCAGGGAGAACAGGCCCCCTGGCACCTTCTACCAGTTCCGCATGCTACCTGTGCAGTTCCTTTGTCCTAACATCAGTGTGAAGTACAAACTCTTAGAAGGG GACGGTCTGCCCTTCCGTTGTGACCCCGACTGTCTGGAGGTGAGCACGCGGTGGGCGCTGGATCGGGAGCTTCAGGAGAAGTATGTGCTGGAGGCTGAGTGCGCAGTGGCAGGCCCTGGAGCCAACAA GGAGAAGGTGGCCGTGTCCTTCCCGGTGACGGTGTATGATGAAGACGACTCCCCGCCCACCTTCTCCGGAGGTGTGGGCACCGCCAGTGCTGTGGTGGAGTTTAAGCGGAAGGAGGGCACTGTGGTAG CCACTCTGCAGGTGTTTGATGCAGATGTGGTGCCAGCATCTGGGGAGCTGGTGAGGCGGTACACAAGCACACTACTCTCAGGGGATTCCTGGGCCCAGCAGACCTTCCGGGTGGAGCACACACCCAAC GAGACCTTGGTCCAGTCCAACAACAACTCCGTGCGGGCAACCATGCACAATTACAAGCTGGTTCTCAACAGGAGCCTGTCCATCTCAGAGAGCCGAGTCCTGCAGCTAGTAGTCCTGGTCAATGACTC AGACTTCCAGGGGCCTGGGTCAGGTGTTCTCTTCCTCCATTTCAACGTGTCTGTGCTGCCTGTCACCCTGAACCTACCCATGGCCTACTCCTTCCCAGTGAATAGGAGAGCCCGCCGTTATGCCCAGA TTGGGAAAGTTTGCGTGGAGAACTGCCAGGAGTTCAGCGGTGTCTCCATCCAGTACAAGCTGCAGCCCTCCAGCACCAACTGCAGTGCCCTAGGTGTGGTCACCTCAACAGAAGACACCTCAGGGACC CTATATGTAAATGACACGGAGGCCCTGCGGCGACCTGAGTGTACCGAGCTTCAGTACACAGTGGTAGCCACTGACCGGCAGACCCGCAGGCAGACCCAGGCTTCGTTAGTCGTCACAGTGGAGGGGAC ATACATTGCAGAAGAAGTGGGCTGCCCCAAGTCCTGTGCAGTAAACAAGAGGCGACCTGAGTGTGAGGAGTGTGGTGGCCTGGGTTCTCCAACTGGCAGATGTGAGTGGCGTCAGGGAGATGGTAAAG GGATCACCAGGAACTTCTCCACCTGTTCTCCTAGCACCAGGACCTGTCCTGATGGCCACTGTGATGCTCTGGAGAGCCGGGATATCAACATTTGCCCCCAGGACTGTCTCCGTGGCCCCATTGTTGGC GGGCATGAGCGAGGGGAGCGCCAGGGGATTAAAGCCGGCTATGGCATCTGCAACTGTTTCCCTGATGAGAAGAAGTGCTTCTGCGAGCCAGAGGACAGCCAGGGCCCATTGTGCGATGAGCTGTGCCG TACGGTCATCACAGCCGCTGTCCTCTTCTCCTTCATAATCTCTGTCCTGCTGTCCACCTTCTGCATCCACCGCTACCACAAGCATGCGCACAAGCCACCCATCGCGTCAGCCGAAATGACCTTCTGCC GGCCGGCCCAGGGCTTCCCAATCAGCTATTCTTCCTCGGGCACCCGCCGGCCCTCACTGGACTCCATGGAGAACCAGGTCTCTGTGGACTCTTTCAAGATCCCGGAGGATCCGAAGTGGGAATTTCCT CGGAAGAACTTAGTTCTTGGGAAAACCCTGGGAGAAGGCGAGTTTGGAAAAGTAGTCAAGGCCACAGCCTTCCGTCTGAAAGGCCGGGCAGGATACACCACAGTGGCTGTGAAAATGCTGAAAGAAAA CGCCTCCCAGAGTGAACTACGAGACCTGCTCTCTGAGTTCAACCTTCTGAAACAAGTCAACCATCCACATGTCATCAAGTTGTACGGGGCTTGCAGCCAGGATGGGCCACTTCTTCTCATTGTGGAGT ATGCAAAGTATGGATCCCTGCGGGGGTTCCTGCGGGACAGCCGCAAGATCGGGCCTGCCTATGTGAGCAGTGGAGGCAGCCGCAATTCCAGCTCCCTGGACCACCCAGACGAAAGGGTGCTGACCATG GGCGACCTCATCTCCTTCGCCTGGCAGATCTCGAGGGGTATGCAGTACTTGGCTGAAATGAAGCTCGTACATCGAGACTTAGCTGCCAGAAACATCTTGGTGGCAGAGGGACGGAAGATGAAGATCTC TGACTTTGGGCTGTCCCGAGATGTTTATGAAGAAGATTCCTATGTGAAGAAAAGCAAGGGCCGGATTCCCGTCAAATGGATGGCAATCGAGTCTCTCTTCGATCACATCTATACCACTCAAAGTGATG TGTGGTCCTTTGGAGTGCTGCTATGGGAGATTGTGACCCTGGGAGGCAACCCCTACCCTGGAATTCCTCCTGAACGACTCTTCAACCTTCTGAAGACAGGCCACAGGATGGAGAGGCCAGACAACTGC AGCGAGGAAATGTACCGCCTGATGCTGCAGTGCTGGAAGCAGGAGCCGGACAAGAGGCCAGTATTTGCTGACATCAGCAAGGATCTGGAGAAGATGATGGTCAAAAGCAGAGACTACTTGGACCTGGC TGCATCCACCCCTTCGGACTCACTGCTCTATGACGATGGGCTCTCGGAAGAGGAGACGCCCCTGGTGGACTGTAACAGTGCTCCCCTCCCGCGCTCCCTCCCTTCCACATGGATTGAAAACAAACTCT ATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCCGATGGCACTAGCACTGGGTTCCCAAGATATGCAAATGATAGTGTATATGCTAACTGGATGGTTTCACCCTCA GCGGCAAAATTAATGGACACATTTGATAGTTAACATTTCTTTGTGAACGGTAATGAACCTCCCAAGGGGGAAGAAACATGCCAAGAGCATCAAGTCCACCGACCACTTTGTGCACATCATACTGGCCA AGACCAGCCTCAGGTGGCAGACTTGTTTTCTGTAGTTTGTTTTAGCTGGTTTCCAAAGTGGTTTTACTTCAAGTAGCCAGTGATCCTCCCTCACGGTGGTCCTCCCTCCTAGCACATCTGCCCCACTG GGTGGGTGCTCTGAGTCTCTGGTTAGATCCCCTTTCCCTTCAGCATTGGGTAGCACCTCTGTTGGTCTGCTCATCAGTAACTACCATGAGCTCTTGTGTTCACATGTGTGGGGTCTGCCATTACAACT TGGATGAGAAATTGTACCTGAACTGTCTGATTTTCCTGGTTGATTAAAAAACTACCACGCACCCCCCCCAAATGTTTTTAACATGAAGCACACATACAAACAACATCAGTTGAAAAACCTGGCTGGAG TGACCTGCCCTTGTTTAGAATGAAAGCCCAGCATAAGTCTGGGCAGTTGGATCCAGCCAGGTCCACTAGGGTTGGAGGGGAGAAGGGAGCCTCAGGGCTGTCCTTGGCCCAGCATATGACATCCTGAA TATAGATTTTTTTTTTGAGTTTTTTTTTTTTTAACCATGTAGCCTTTTCTTAGGAAAACGTTGTTTCTGACGTGGTTAAGCGGCTCTTAGATTTAGCACAATTGAGAGATTGGGTGTTGCCCTTGCTT GTACAAGGCAGCTCGAAAGAAGTGGCCCCATAAGACACAGTCCCCCTGTTGAGCCCAGGGCATCATTCTCCTGTTCAGCGCTGCGTGACACCTACCCGCAGACCAGAACAGGGTGAAGAAGCAGGGCA TTTGGAGTGGAGCAGCCTTCAGGCCCAGAATTGCTGGCAGCAGAGGCCTTGAGCCACAAATGCTGCACCCCCAGCACAGCATTCCGCAGAACGCCCTACCCACCTGAGAGTGTGCTTGACCTCTGATG GGGCAGGCAGGTCTGCCTTGTTTTAATCACTACCTTGTCAGCTCATGCCCGGAGGGAAGGACAGTTCATCTAGTTGTATTAGAGGTTTCCCTGACAACGACTGAGGTGAGAGAATGAGGTTTTGGCTC TTATAGAGCTTGTGTGAAAGGCACATGGATCAGCTCTCCCCATCCGACATTTATGCTGCTGCTATGGTACGTGTTTTGGTCTCCTCCGTTCTGACCACGACTCCCGTGTAAGGTTCTTGTCTTTCTGT ACTGACGGTTGTAGCCTCAGACATTCTGCACTCCTCTGGGGTTTTAGGGGTGGCTCTTGGAAGTTTCTTTGGCTGTCTATGGACTTGTCACTTCCCACGAAAAGGTCACATTACCAAAACACTGCCTG GTCTTCAGACTTCAAGCACTGTGATAGGACTTTTAAATAGTCGTAATAAAATACTATATTTTATGGGCATTTCACAAACACAGTAAAATTGTGACATTTTATGTGGCTGAGAATGCTCAGATAAGTAC ACCGGATAGAGCCTTACGGAGTGTGTGTAATACTTGTGTGTGCACACAGCCAGACGGAAAGATGAAAAATGCTTATTTCAGCATATAATATGGCTTTAGTTTGGGCCATTTTTCTTTCAGATACACTG TGATAAGATTTTTTTTAATATAAATATCTCTAGTCATGGGATCCATTTTGTTTTTCAGATGTGCTTAATAATAGTTTTATTAAATGCAGAAATACAGATAAGTTCAAATTACTCAACATGCCTACACA GTATTGCTACAGCAGGTTTAGCTTCAAGGGCTGAGCTCCATGTCTAAATAGCTGACCCATCTGTGGGGAATTAACACTTGACTAATAACCATTTGTCTGTCTGTTCCTGAGATACAAAAGTACCCATA CTTGTTAAAAGTACCTATACCTGTTAGCACTATCAGACAGATTTTTCATCTACATATATGCAGAAGTTACCACATATTAAATATTACTGAGTATTAAGTAGCAATCTGTCAGCCACTAAAATTTGTAA GATCCATTTAAGAAAGGCTATTAAACCGTACCATGTTGACTTGTTTTTGTAATCAAGGTGACTAAGGAAATGATTTCAGCTGTGTAAATAAAATTATAAATC
hide sequence
RefSeq Acc Id:
XM_063285561 ⟹ XP_063141631
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 4 152,998,344 - 153,032,403 (-) NCBI
RefSeq Acc Id:
NP_036775 ⟸ NM_012643
- Peptide Label:
isoform a precursor
- UniProtKB:
G3V9H8 (UniProtKB/Swiss-Prot), Q9EPA1 (UniProtKB/Swiss-Prot), Q9EPC3 (UniProtKB/Swiss-Prot)
- Sequence:
MAKARSGAAGLGLKLFLLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAPGEVPSFRLGQYLYGVYRTRLHENDWIHIDSGTGLLYLNQSLDHSSWEQLSIRNGGFPLLTVFLQVFLG STAQREGECHWPGCARVYFSFINDTFPNCSSFKARDLCTPETGVSFRIRENRPPGTFYQFRMLPVQFLCPNISVKYKLLEGDGLPFRCDPDCLEVSTRWALDRELQEKYVLEAECAVAGPGANKEKVA VSFPVTVYDEDDSPPTFSGGVGTASAVVEFKRKEGTVVATLQVFDADVVPASGELVRRYTSTLLSGDSWAQQTFRVEHTPNETLVQSNNNSVRATMHNYKLVLNRSLSISESRVLQLVVLVNDSDFQG PGSGVLFLHFNVSVLPVTLNLPMAYSFPVNRRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSTNCSALGVVTSTEDTSGTLYVNDTEALRRPECTELQYTVVATDRQTRRQTQASLVVTVEGTYIAE EVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDALESRDINICPQDCLRGPIVGGHERGERQGIKAGYGICNCFPDEKKCFCEPEDSQGPLCDELCRTVIT AAVLFSFIISVLLSTFCIHRYHKHAHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQS ELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGL SRDVYEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTP SDSLLYDDGLSEEETPLVDCNSAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTRADGTSTGFPRYANDSVYANWMVSPSAAKLMDTFDS
hide sequence
RefSeq Acc Id:
NP_001103569 ⟸ NM_001110099
- Peptide Label:
isoform b precursor
- UniProtKB:
A6IL58 (UniProtKB/TrEMBL)
- Sequence:
MAKARSGAAGLGLKLFLLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAPGEVPSFRLGQYLYGVYRTRLHENDWIHIDSGTGLLYLNQSLDHSSWEQLSIRNGGFPLLTVFLQVFLG STAQREGECHWPGCARVYFSFINDTFPNCSSFKARDLCTPETGVSFRIRENRPPGTFYQFRMLPVQFLCPNISVKYKLLEGDGLPFRCDPDCLEVSTRWALDRELQEKYVLEAECAVAGPGANKEKVA VSFPVTVYDEDDSPPTFSGGVGTASAVVEFKRKEGTVVATLQVFDADVVPASGELVRRYTSTLLSGDSWAQQTFRVEHTPNETLVQSNNNSVRATMHNYKLVLNRSLSISESRVLQLVVLVNDSDFQG PGSGVLFLHFNVSVLPVTLNLPMAYSFPVNRRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSTNCSALGVVTSTEDTSGTLYVNDTEALRRPECTELQYTVVATDRQTRRQTQASLVVTVEGTYIAE EVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDALESRDINICPQDCLRGPIVGGHERGERQGIKAGYGICNCFPDEKKCFCEPEDSQGPLCDELCRTVIT AAVLFSFIISVLLSTFCIHRYHKHAHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQS ELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGL SRDVYEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTP SDSLLYDDGLSEEETPLVDCNSAPLPRSLPSTWIENKLYGRISHAFTRF
hide sequence
Ensembl Acc Id:
ENSRNOP00000047793 ⟸ ENSRNOT00000047685
RefSeq Acc Id:
XP_063141631 ⟸ XM_063285561
- Peptide Label:
isoform X1
BioCyc Gene
G2FUF-43236
BioCyc
Ensembl Genes
ENSRNOG00000014751
Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript
ENSRNOT00000047685.5
UniProtKB/Swiss-Prot
Gene3D-CATH
Cadherins
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Phosphorylase Kinase, domain 1
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Transferase(Phosphotransferase) domain 1
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro
Cadherin-like_dom
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Cadherin-like_sf
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Kinase-like_dom_sf
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Prot_kinase_dom
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Protein_kinase_ATP_BS
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ret_CLD1
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ret_CLD3
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RET_CLD4
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RET_CRD
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RTK
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ser-Thr/Tyr_kinase_cat_dom
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Tyr_kinase_AS
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Tyr_kinase_cat_dom
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Tyr_kinase_Ret_rcpt
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report
rno:24716
UniProtKB/Swiss-Prot
NCBI Gene
24716
ENTREZGENE
PANTHER
PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TYROSINE-PROTEIN KINASE RECEPTOR
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam
Cadherin
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PK_Tyr_Ser-Thr
UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
RET_CLD1
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RET_CLD3
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RET_CLD4
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RET_CRD
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen
Ret
PhenoGen
PIRSF
TyrPK_receptor_Ret
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS
TYRKINASE
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE
CADHERIN_2
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROTEIN_KINASE_ATP
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROTEIN_KINASE_DOM
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROTEIN_KINASE_TYR
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx
ENSRNOG00000014751
RatGTEx
SMART
TyrKc
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP
Cadherin-like
UniProtKB/TrEMBL
Protein kinase-like (PK-like)
UniProtKB/TrEMBL
SSF49313
UniProtKB/Swiss-Prot
SSF56112
UniProtKB/Swiss-Prot
UniProt
A6IL58
ENTREZGENE, UniProtKB/TrEMBL
G3V9H8
ENTREZGENE
Q63197_RAT
UniProtKB/TrEMBL
Q9EPA1
ENTREZGENE
Q9EPC3
ENTREZGENE
RET_RAT
UniProtKB/Swiss-Prot
UniProt Secondary
Q9EPA1
UniProtKB/Swiss-Prot
Q9EPC3
UniProtKB/Swiss-Prot
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2003-04-09
Ret
ret proto-oncogene
Ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung disease)
Name updated
629478
APPROVED
2002-06-10
Ret
Ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung disease)
Symbol and Name status set to approved
70586
APPROVED
Note Type
Note
Reference
gene_function
receptor for glial cell line-derived neurotrophic factor family ligands
1304247
gene_product
member of the receptor tyrosine kinase family
633884