Mobp (myelin-associated oligodendrocyte basic protein) - Rat Genome Database

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Pathways
Gene: Mobp (myelin-associated oligodendrocyte basic protein) Rattus norvegicus
Analyze
Symbol: Mobp
Name: myelin-associated oligodendrocyte basic protein
RGD ID: 3101
Description: A structural constituent of myelin sheath. Involved in central nervous system myelin formation. Predicted to be located in mitochondrion. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in frontotemporal dementia. Orthologous to human MOBP (myelin associated oligodendrocyte basic protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC105491; Mobp81; Mobp81p; myelin-associated oligodendrocytic basic protein; Myelin-associated/Oligodendrocytic Basic Protein-81; RNMOBP81P
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88128,747,117 - 128,777,238 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8128,747,232 - 128,777,936 (+)EnsemblGRCr8
mRatBN7.28119,869,504 - 119,899,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,869,626 - 119,899,563 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8125,449,916 - 125,475,469 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08123,648,952 - 123,674,506 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08121,489,423 - 121,515,242 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,824,420 - 128,854,492 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,824,508 - 128,850,358 (+)Ensemblrn6Rnor6.0
Rnor_5.08128,025,119 - 128,055,171 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48125,118,618 - 125,144,099 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8119,014,616 - 119,040,060 (+)NCBICelera
RGSC_v3.18125,138,354 - 125,163,833 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Selective effect of hypothyroidism on expression of myelin markers during development. Barradas PC, etal., J Neurosci Res. 2001 Oct 15;66(2):254-61. doi: 10.1002/jnr.1218.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Myelin-associated oligodendrocytic basic protein mRNAs reside at different subcellular locations. Gould RM, etal., J Neurochem 1999 Nov;73(5):1913-24.
4. Developmental expression of the myelin gene MOBP in the rat nervous system. Holz A and Schwab ME, J Neurocytol. 1997 Jul;26(7):467-77. doi: 10.1023/a:1018529323734.
5. Myelin-associated oligodendrocytic basic protein: identification of an encephalitogenic epitope and association with multiple sclerosis. Holz A, etal., J Immunol. 2000 Jan 15;164(2):1103-9. doi: 10.4049/jimmunol.164.2.1103.
6. Molecular and developmental characterization of novel cDNAs of the myelin-associated/oligodendrocytic basic protein. Holz A, etal., J Neurosci 1996 Jan 15;16(2):467-77.
7. Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia. Irwin DJ, etal., Neurology. 2014 Aug 5;83(6):502-9. doi: 10.1212/WNL.0000000000000668. Epub 2014 Jul 3.
8. Gene expression changes in a rat model of oxygen-induced retinopathy. Lee NE, etal., Korean J Ophthalmol. 2011 Feb;25(1):42-7. doi: 10.3341/kjo.2011.25.1.42. Epub 2011 Jan 17.
9. Alterations of myelin proteins in inflammatory demyelination of BALB/c mice caused by Angiostrongylus cantonensis. Lin KY, etal., Vet Parasitol. 2010 Jul 15;171(1-2):74-80. doi: 10.1016/j.vetpar.2010.03.019. Epub 2010 Mar 30.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
13. Cloning and expression of myelin-associated oligodendrocytic basic protein. A novel basic protein constituting the central nervous system myelin. Yamamoto Y, etal., J Biol Chem 1994 Dec 16;269(50):31725-30.
Additional References at PubMed
PMID:10077700   PMID:12477932   PMID:15489334   PMID:15625715   PMID:17634366   PMID:18614015   PMID:22871113  


Genomics

Comparative Map Data
Mobp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88128,747,117 - 128,777,238 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8128,747,232 - 128,777,936 (+)EnsemblGRCr8
mRatBN7.28119,869,504 - 119,899,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,869,626 - 119,899,563 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8125,449,916 - 125,475,469 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08123,648,952 - 123,674,506 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08121,489,423 - 121,515,242 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,824,420 - 128,854,492 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,824,508 - 128,850,358 (+)Ensemblrn6Rnor6.0
Rnor_5.08128,025,119 - 128,055,171 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48125,118,618 - 125,144,099 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8119,014,616 - 119,040,060 (+)NCBICelera
RGSC_v3.18125,138,354 - 125,163,833 (+)NCBI
Cytogenetic Map8q32NCBI
MOBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38339,467,680 - 39,529,497 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl339,467,172 - 39,529,479 (+)Ensemblhg38GRCh38
GRCh37339,509,171 - 39,570,988 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,484,074 - 39,542,863 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34339,518,557 - 39,540,989NCBI
Celera339,450,698 - 39,509,485 (+)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef339,552,592 - 39,614,603 (+)NCBIHuRef
CHM1_1339,460,108 - 39,522,029 (+)NCBICHM1_1
T2T-CHM13v2.0339,480,633 - 39,542,424 (+)NCBIT2T-CHM13v2.0
Mobp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,978,740 - 120,010,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,978,773 - 120,010,550 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389120,149,742 - 120,181,488 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,149,707 - 120,181,484 (+)Ensemblmm10GRCm38
MGSCv379120,058,860 - 120,085,209 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369119,998,440 - 120,030,182 (+)NCBIMGSCv36mm8
Celera9120,618,557 - 120,644,888 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map971.41NCBI
Mobp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542029,914,118 - 29,925,176 (-)Ensembl
ChiLan1.0NW_00495542029,902,036 - 29,957,364 (-)NCBIChiLan1.0ChiLan1.0
MOBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2239,427,476 - 39,494,355 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1339,432,238 - 39,499,116 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0339,372,102 - 39,450,066 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1339,651,728 - 39,715,632 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl339,688,104 - 39,699,486 (+)EnsemblpanPan2panpan1.1
MOBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1239,121,277 - 9,176,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl239,121,319 - 9,161,972 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha239,156,665 - 9,211,227 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0239,406,125 - 9,460,980 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl239,406,083 - 9,460,975 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1239,219,099 - 9,273,643 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0239,362,022 - 9,416,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0239,355,681 - 9,409,917 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mobp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,525,415 - 195,572,004 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647328,689,242 - 28,697,772 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647328,663,986 - 28,709,394 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11324,138,078 - 24,186,838 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21326,450,254 - 26,497,554 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MOBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1221,041,714 - 1,077,514 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl221,041,783 - 1,079,241 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041166,166,889 - 166,222,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mobp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473078,762,075 - 78,773,422 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473078,759,681 - 78,794,632 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mobp
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18111,373,832 - 111,391,941 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:415
Count of miRNA genes:236
Interacting mature miRNAs:277
Transcripts:ENSRNOT00000025279, ENSRNOT00000025343, ENSRNOT00000041868
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat

Markers in Region
D8Wox13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,893,153 - 119,893,319 (+)MAPPERmRatBN7.2
Rnor_6.08128,848,035 - 128,848,200NCBIRnor6.0
Rnor_5.08128,048,720 - 128,048,885UniSTSRnor5.0
RGSC_v3.48125,141,773 - 125,141,938UniSTSRGSC3.4
Celera8119,038,304 - 119,038,469UniSTS
Cytogenetic Map8q32UniSTS
RH127596  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88128,772,812 - 128,773,021 (+)Marker Load Pipeline
mRatBN7.28119,895,179 - 119,895,388 (+)MAPPERmRatBN7.2
Rnor_6.08128,850,061 - 128,850,269NCBIRnor6.0
Rnor_5.08128,050,746 - 128,050,954UniSTSRnor5.0
RGSC_v3.48125,143,799 - 125,144,007UniSTSRGSC3.4
Celera8119,039,760 - 119,039,968UniSTS
RH 3.4 Map81286.9UniSTS
Cytogenetic Map8q32UniSTS
RH144588  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,891,405 - 119,891,565 (+)MAPPERmRatBN7.2
Rnor_6.08128,846,289 - 128,846,448NCBIRnor6.0
Rnor_5.08128,046,974 - 128,047,133UniSTSRnor5.0
RGSC_v3.48125,140,027 - 125,140,186UniSTSRGSC3.4
Celera8119,036,558 - 119,036,717UniSTS
RH 3.4 Map81286.9UniSTS
Cytogenetic Map8q32UniSTS
BG376552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,887,635 - 119,887,782 (+)MAPPERmRatBN7.2
Rnor_6.08128,842,519 - 128,842,665NCBIRnor6.0
Rnor_5.08128,043,204 - 128,043,350UniSTSRnor5.0
RGSC_v3.48125,136,257 - 125,136,403UniSTSRGSC3.4
Celera8119,032,788 - 119,032,934UniSTS
RH 3.4 Map81287.0UniSTS
Cytogenetic Map8q32UniSTS
BI281206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,899,047 - 119,899,198 (+)MAPPERmRatBN7.2
Rnor_6.08128,853,929 - 128,854,079NCBIRnor6.0
Rnor_5.08128,054,614 - 128,054,764UniSTSRnor5.0
RGSC_v3.48125,147,667 - 125,147,817UniSTSRGSC3.4
Celera8119,043,628 - 119,043,778UniSTS
RH 3.4 Map81314.4UniSTS
Cytogenetic Map8q32UniSTS
Mobp  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,887,003 - 119,887,726 (+)MAPPERmRatBN7.2
Rnor_6.08128,841,887 - 128,842,609NCBIRnor6.0
Rnor_5.08128,042,572 - 128,043,294UniSTSRnor5.0
RGSC_v3.48125,135,625 - 125,136,347UniSTSRGSC3.4
Celera8119,032,156 - 119,032,878UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 9 32 141 60 58 28 42 28 6 186 104 9 115 37 65 30 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001389272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001389273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_356705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_594173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_594174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF157498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC161856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X87900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000025279   ⟹   ENSRNOP00000025279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8128,747,250 - 128,773,055 (+)Ensembl
mRatBN7.2 Ensembl8119,869,626 - 119,887,856 (+)Ensembl
Rnor_6.0 Ensembl8128,829,680 - 128,842,739 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000025343   ⟹   ENSRNOP00000025344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8119,869,628 - 119,894,869 (+)Ensembl
Rnor_6.0 Ensembl8128,824,508 - 128,850,358 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104512   ⟹   ENSRNOP00000080049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8128,747,274 - 128,777,196 (+)Ensembl
mRatBN7.2 Ensembl8119,869,644 - 119,899,563 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130926   ⟹   ENSRNOP00000112149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8128,747,232 - 128,777,236 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148240   ⟹   ENSRNOP00000105313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8128,747,232 - 128,777,936 (+)Ensembl
RefSeq Acc Id: NM_001389272   ⟹   NP_001376201
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,232 - 128,765,494 (+)NCBI
mRatBN7.28119,869,602 - 119,887,859 (+)NCBI
RefSeq Acc Id: NM_001389273   ⟹   NP_001376202
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,232 - 128,765,494 (+)NCBI
mRatBN7.28119,869,602 - 119,887,859 (+)NCBI
RefSeq Acc Id: NM_012720   ⟹   NP_036852
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,232 - 128,773,113 (+)NCBI
mRatBN7.28119,869,602 - 119,895,480 (+)NCBI
Rnor_6.08128,824,508 - 128,850,361 (+)NCBI
Rnor_5.08128,025,119 - 128,055,171 (+)NCBI
RGSC_v3.48125,118,618 - 125,144,099 (+)RGD
Celera8119,014,616 - 119,040,060 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080854   ⟹   XP_038936782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,117 - 128,777,238 (+)NCBI
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080855   ⟹   XP_038936783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,117 - 128,777,238 (+)NCBI
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080856   ⟹   XP_038936784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,117 - 128,777,238 (+)NCBI
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080857   ⟹   XP_038936785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,174 - 128,777,238 (+)NCBI
mRatBN7.28119,869,543 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080858   ⟹   XP_038936786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,117 - 128,777,238 (+)NCBI
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080859   ⟹   XP_038936787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,147 - 128,777,238 (+)NCBI
mRatBN7.28119,869,517 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080860   ⟹   XP_038936788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,117 - 128,777,238 (+)NCBI
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080861   ⟹   XP_038936789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,174 - 128,777,238 (+)NCBI
mRatBN7.28119,869,544 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080862   ⟹   XP_038936790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,137 - 128,777,238 (+)NCBI
mRatBN7.28119,869,513 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080863   ⟹   XP_038936791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,162 - 128,777,238 (+)NCBI
mRatBN7.28119,869,533 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_063264939   ⟹   XP_063121009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,148 - 128,777,238 (+)NCBI
RefSeq Acc Id: XM_063264940   ⟹   XP_063121010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88128,747,174 - 128,777,238 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001376201 (Get FASTA)   NCBI Sequence Viewer  
  NP_001376202 (Get FASTA)   NCBI Sequence Viewer  
  NP_036852 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936782 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936783 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936784 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936785 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936786 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936787 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936788 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936789 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936790 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936791 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121009 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121010 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD44968 (Get FASTA)   NCBI Sequence Viewer  
  AAH87694 (Get FASTA)   NCBI Sequence Viewer  
  AAI61856 (Get FASTA)   NCBI Sequence Viewer  
  BAA05657 (Get FASTA)   NCBI Sequence Viewer  
  BAA05658 (Get FASTA)   NCBI Sequence Viewer  
  CAA61151 (Get FASTA)   NCBI Sequence Viewer  
  CAA61795 (Get FASTA)   NCBI Sequence Viewer  
  CAA61796 (Get FASTA)   NCBI Sequence Viewer  
  CAA62039 (Get FASTA)   NCBI Sequence Viewer  
  EDL76871 (Get FASTA)   NCBI Sequence Viewer  
  EDL76873 (Get FASTA)   NCBI Sequence Viewer  
  EDL76876 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025279.3
  ENSRNOP00000025344.5
  ENSRNOP00000080049.1
  ENSRNOP00000105313
  ENSRNOP00000112149
GenBank Protein Q63327 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_036852   ⟸   NM_012720
- Peptide Label: isoform 1
- UniProtKB: A6I401 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025279   ⟸   ENSRNOT00000025279
Ensembl Acc Id: ENSRNOP00000025344   ⟸   ENSRNOT00000025343
RefSeq Acc Id: XP_038936786   ⟸   XM_039080858
- Peptide Label: isoform X1
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936782   ⟸   XM_039080854
- Peptide Label: isoform X1
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936783   ⟸   XM_039080855
- Peptide Label: isoform X1
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936784   ⟸   XM_039080856
- Peptide Label: isoform X1
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936788   ⟸   XM_039080860
- Peptide Label: isoform X2
- UniProtKB: A6I402 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936790   ⟸   XM_039080862
- Peptide Label: isoform X3
- UniProtKB: A6I401 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936787   ⟸   XM_039080859
- Peptide Label: isoform X1
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936791   ⟸   XM_039080863
- Peptide Label: isoform X3
- UniProtKB: A6I401 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936785   ⟸   XM_039080857
- Peptide Label: isoform X1
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936789   ⟸   XM_039080861
- Peptide Label: isoform X2
- UniProtKB: A6I402 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001376201   ⟸   NM_001389272
- Peptide Label: isoform 2
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001376202   ⟸   NM_001389273
- Peptide Label: isoform 2
- UniProtKB: Q64266 (UniProtKB/Swiss-Prot),   Q63519 (UniProtKB/Swiss-Prot),   Q63343 (UniProtKB/Swiss-Prot),   Q63328 (UniProtKB/Swiss-Prot),   Q63327 (UniProtKB/Swiss-Prot),   Q9QZV5 (UniProtKB/Swiss-Prot),   B1WBR5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080049   ⟸   ENSRNOT00000104512
RefSeq Acc Id: XP_063121009   ⟸   XM_063264939
- Peptide Label: isoform X2
- UniProtKB: A6I402 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121010   ⟸   XM_063264940
- Peptide Label: isoform X3
- UniProtKB: A6I401 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105313   ⟸   ENSRNOT00000148240
Ensembl Acc Id: ENSRNOP00000112149   ⟸   ENSRNOT00000130926
Protein Domains
FYVE-type zinc finger

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63327-F1-model_v2 AlphaFold Q63327 1-170 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696384
Promoter ID:EPDNEW_R6907
Type:multiple initiation site
Name:Mobp_1
Description:myelin-associated oligodendrocyte basic protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08128,824,482 - 128,824,542EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3101 AgrOrtholog
BioCyc Gene G2FUF-28751 BioCyc
Ensembl Genes ENSRNOG00000018700 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025279.6 UniProtKB/Swiss-Prot
  ENSRNOT00000025343.9 UniProtKB/Swiss-Prot
  ENSRNOT00000104512.1 UniProtKB/Swiss-Prot
  ENSRNOT00000130926 ENTREZGENE
  ENSRNOT00000148240 ENTREZGENE
IMAGE_CLONE IMAGE:7320248 IMAGE-MGC_LOAD
InterPro FYVE_2 UniProtKB/Swiss-Prot
  Intracell_Transport_Effector UniProtKB/Swiss-Prot
KEGG Report rno:25037 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187383 IMAGE-MGC_LOAD
NCBI Gene 25037 ENTREZGENE
PANTHER MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED UniProtKB/Swiss-Prot
  RAB EFFECTOR MYRIP UniProtKB/Swiss-Prot
Pfam FYVE_2 UniProtKB/Swiss-Prot
PhenoGen Mobp PhenoGen
RatGTEx ENSRNOG00000018700 RatGTEx
TIGR TC208077
UniProt A6I401 ENTREZGENE, UniProtKB/TrEMBL
  A6I402 ENTREZGENE, UniProtKB/TrEMBL
  B1WBR5 ENTREZGENE, UniProtKB/TrEMBL
  MOBP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q63328 ENTREZGENE
  Q63343 ENTREZGENE
  Q63519 ENTREZGENE
  Q64266 ENTREZGENE
  Q9QZV5 ENTREZGENE
UniProt Secondary Q63328 UniProtKB/Swiss-Prot
  Q63343 UniProtKB/Swiss-Prot
  Q63519 UniProtKB/Swiss-Prot
  Q64266 UniProtKB/Swiss-Prot
  Q9QZV5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Mobp  myelin-associated oligodendrocyte basic protein  Mobp  myelin-associated oligodendrocytic basic protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Mobp  myelin-associated oligodendrocytic basic protein  Mobp81  Myelin-associated/Oligodendrocytic Basic Protein-81  Symbol and Name updated 625702 APPROVED
2002-06-10 Mobp81  Myelin-associated/Oligodendrocytic Basic Protein-81      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expression restricted to the CNS myelin 633191
gene_product member of the central nervous system (CNS) myelin-constituting protein family 633191
gene_product member of the central nervous system (CNS) myelin-constituting proteins 633191